Mikayla J Baker, Alisha Kamboj, Amanda C Maltry, Raymond G Areaux, Andrew R Harrison, Ali Mokhtarzadeh
{"title":"Bilateral orbital inflammation in a pediatric patient with eosinophilic granulomatosis with polyangiitis.","authors":"Mikayla J Baker, Alisha Kamboj, Amanda C Maltry, Raymond G Areaux, Andrew R Harrison, Ali Mokhtarzadeh","doi":"10.1080/01676830.2024.2448813","DOIUrl":"10.1080/01676830.2024.2448813","url":null,"abstract":"<p><p>A 5-year-old female presented to the ophthalmology clinic with one month of left upper eyelid ptosis and three months of intermittent wheezing and coughing. MRI of the brain and orbits revealed infiltrative enhancement involving both orbits, including the retro-maxillary space, maxillary sinus walls, greater wing of the sphenoid, and possibly the left cavernous sinus. She experienced acute respiratory decompensation in the setting of pansinusitis and tree-in-bud nodular pulmonary opacifications. Laboratory workup revealed anemia, thrombocytosis, and elevated inflammatory markers. An orbitotomy with biopsy demonstrated an eosinophil-rich granulomatous infiltrate, consistent with eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss syndrome. The patient was placed on high-dose steroids and mepolizumab. To our knowledge, this patient represents the youngest case of EGPA with orbital involvement. Further, this case illustrates the importance of prompt orbital biopsy to provide a timely, unified diagnosis, enabling specialists to initiate appropriate disease management to reduce morbidity and mortality.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"588-591"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Niko J Viskari, Minna H Vesaluoma, Juho O Wedenoja, Marita S Uusitalo
{"title":"Oculoplastic complications in patients with adenoviral keratoconjunctivitis.","authors":"Niko J Viskari, Minna H Vesaluoma, Juho O Wedenoja, Marita S Uusitalo","doi":"10.1080/01676830.2025.2481935","DOIUrl":"10.1080/01676830.2025.2481935","url":null,"abstract":"<p><strong>Purpose: </strong>Adenoviruses and other viral superficial eye infections may cause long-lasting complications, including conjunctival scarring, synechiae, and lacrimal system obstructions. However, their incidence is not established. Here, we set out to assess possible oculoplastic complications and need for surgical procedures in patients with adenoviral conjunctivitis.</p><p><strong>Methods: </strong>This Finnish register-based retrospective study includes patients with adenoviral conjunctivitis treated at Helsinki University Hospital eye clinic, Finland, during adenoviral outbreak in the winter 2017-2018. Of these identified 168 patients, with median age of 43 years (range 0-83 years), 92 were female and 76 were male. 134 patients presented with a bilateral and 34 with a unilateral disease. Viral cell cultures revealed adenovirus serotypes 4 and 8. The medical records were reviewed in 2021-2022 to assess any oculoplastic complications and related surgical procedures.</p><p><strong>Result: </strong>After adenoviral infection, two patients presented with chronic tearing and were diagnosed with canalicular obstruction. One was primarily treated with silicone tube intubation. The canalicular obstruction of the other patient was released by lacrimal irrigation only, after which the patient remained symptom free. No other oculoplastic complications were found.</p><p><strong>Conclusions: </strong>Adenoviral conjunctivitis with even severe inflammation of the anterior segment rarely causes oculoplastic complications requiring surgical interventions.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"530-534"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James Diller Murphy, Almila Sarıgül Sezenöz, Federica Mingardo, Victor M Elner, Hakan Demirci
{"title":"Ectopic orbital brain tissue with perineural cerebrospinal fluid leakage: a case report.","authors":"James Diller Murphy, Almila Sarıgül Sezenöz, Federica Mingardo, Victor M Elner, Hakan Demirci","doi":"10.1080/01676830.2025.2483351","DOIUrl":"10.1080/01676830.2025.2483351","url":null,"abstract":"<p><p>A newborn girl presented with perinatal left periorbital swelling and was treated with antibiotics for 7 days, without improvement. At 9-days-old, ophthalmic examination showed an inferomedial soft, palpable, mobile mass with prominent dilated overlying conjunctival vessels and a morning glory optic disc anomaly of the left eye. Magnetic resonance imaging (MRI) revealed a complex, multilobulated mass displacing the globe superolaterally. Subtotal excision revealed benign ectopic brain tissue. Subsequently, swelling and proptosis recurred. Computed tomography (CT) with cisternogram showed cerebrospinal fluid (CSF) leakage from the optic nerve sheath into the mass. The mass was successfully excised resulting in a satisfactory outcome. This case highlights an association between ectopic brain tissue and CSF leakage, which may be found using CT cisternogram for diagnosis and surgical planning.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"649-653"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrograde circular intubation for the failed passage of a pigtail lacrimal probe in the management of non-specific inflammatory punctum occlusion.","authors":"Hesham A Ibrahim, Heba Nabil Sabry","doi":"10.1080/01676830.2025.2469318","DOIUrl":"10.1080/01676830.2025.2469318","url":null,"abstract":"<p><strong>Purpose: </strong>to describe the role of Retrograde Circular Intubation (RCI) technique in the management of non-specific inflammatory punctum occlusion (NIPO).</p><p><strong>Methods: </strong>patients with NIPO who failed conservative treatment underwent 3-snip mini rectangular punctoplasty with adjunctive use of circular canalicular intubation. When the use of the pigtail lacrimal probe was not safely possible, circular intubation was accomplished by the RCI technique. A loop of 6/0 polypropylene suture was introduced into the upper lacrimal drainage system in a retrograde manner from the nose by pulling its two ends up from the puncta with 2/0 polypropylene sutures. The latter were placed between the punctum and the nose by a canulated probe or a Ritleng lacrimal probe (https://youtu.be/n31NKdWIUJM).</p><p><strong>Results: </strong>Thirty-two patients (64 eyes) underwent circular intubation as an adjunct to the 3-snip mini rectangular punctoplasty. In 9 eyes (14%) the pigtail lacrimal probe couldn't pass safely across the upper lacrimal drainage system. Circular tube insertion was still possible with the RCI technique. Circular tubes were removed after two months. Over two years of follow-up, 27 patients (84%) maintained a patent punctum.</p><p><strong>Conclusion: </strong>NIPO not responding to conservative measures can be managed surgically under an umbrella of medications. Circular canalicular intubation with its excellent stability and low morbidity is a valuable adjunctive to the 3-snip mini rectangular punctoplasty. When the passage of the pigtail lacrimal probe fails, circular tubes can be inserted with the RCI technique.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"607-613"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amee D Azad, Lisa Y Lin, Carolina Chiou, Douglas Dembinski, Christopher D Dwyer, Dane Slentz, Natalie Wolkow
{"title":"A case presentation of a pressurized diesel injury to the orbit, face, and neck.","authors":"Amee D Azad, Lisa Y Lin, Carolina Chiou, Douglas Dembinski, Christopher D Dwyer, Dane Slentz, Natalie Wolkow","doi":"10.1080/01676830.2025.2465487","DOIUrl":"10.1080/01676830.2025.2465487","url":null,"abstract":"<p><p>High-pressure diesel soft tissue injuries are uncommon, especially in the orbit. These injuries can initially have a deceivingly benign clinical appearance and may radiographically mimic soft tissue emphysema but can rapidly progress with vision-threatening outcomes; cases of complete vision loss and loss of eye have been reported. Early diagnosis and intervention are essential to minimize chemical injury to soft tissues and vital structures. We present a case of a severe injury from compressed diesel to the orbit, face, and neck requiring multidisciplinary management, serial debridements, high-dose corticosteroids, and staged reconstruction with an excellent visual outcome.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"602-606"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frank Mei, Liane O Dallalzadeh, Preston Choi, Munevver Duran, Jennifer H Cao, Phillip A Tenzel, Ronald Mancini
{"title":"Adjunct botulinum toxin for cicatricial pemphigoid.","authors":"Frank Mei, Liane O Dallalzadeh, Preston Choi, Munevver Duran, Jennifer H Cao, Phillip A Tenzel, Ronald Mancini","doi":"10.1080/01676830.2025.2470988","DOIUrl":"10.1080/01676830.2025.2470988","url":null,"abstract":"<p><p>Cicatricial changes secondary to conjunctivitis associated with pemphigoid can include subconjunctival fibrosis, forniceal shortening, symblepharon with resultant entropion and trichiasis. This can ultimately lead to limbal stem cell deficiency and irreversible corneal keratopathy. Herein, we present a case series of three patients at a single academic institution between 2022 and 2024 that underwent botulinum toxin-A injection for lower eyelid cicatricial entropion as a temporizing treatment due to active cicatrizing conjunctivitis. All patients reported subjective improvement in ocular irritation following injection. All patients demonstrated improvement in their eyelid margin position with decreased orbicularis override and improved anterior trajectory of lashes. No patient experienced exacerbation of their pemphigoid and all patients opted for serial injections (mean of 4.3 treatments). This series demonstrates that botulinum toxin-A is an effective tool in the limited armamentum of treatment options for patients with cicatrizing entropion during phases of active cicatrizing conjunctivitis when more definitive conjunctival incisional surgeries are contraindicated.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"614-618"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel B Azzam, Alicia Casella, Yi Ling Dai, M Reza Vagefi
{"title":"Nationwide orbital decompression volume, surgical approach, and subspecialty distribution patterns within the center for medicare and medicaid services population in the era of teprotumumab.","authors":"Daniel B Azzam, Alicia Casella, Yi Ling Dai, M Reza Vagefi","doi":"10.1080/01676830.2025.2475844","DOIUrl":"10.1080/01676830.2025.2475844","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate nationwide practice patterns in orbital decompression surgery for thyroid eye disease (TED) after approval of teprotumumab in January 2020.</p><p><strong>Methods: </strong>This retrospective study analyzed the Centers for Medicare and Medicaid Services (CMS) database before (2016-2019) and after teprotumumab approval (2020-2023). External (CPT codes 67414 and 67445) and endoscopic (CPT 31292 and 31293) approaches were included. Controls were cataract surgery (CPT 66984) and upper blepharoplasty (CPT 15822 and 15823). Main outcomes were orbital decompression volume, surgical approach, and subspecialty distribution.</p><p><strong>Results: </strong>In total 4,534 orbital decompressions were billed to CMS from 2016 to 2023. Nationwide orbital decompression volume significantly declined (-37%, <i>p</i> < 0.001) in the post-teprotumumab period, even when controlling relative to cataract surgery (<i>p</i> < 0.001) or upper blepharoplasty (<i>p</i> = 0.010). This was attributed to decreased external orbital decompressions (-41%, <i>p</i> < 0.001), while endoscopic approach was less impacted (-28%, <i>p</i> = 0.007). Specialty distribution trended away from oculofacial plastic surgeons (-10%) toward otolaryngologists (+18%) (<i>p</i> < 0.001). The proportion of endoscopic approach significantly grew (+13%, <i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>A nationwide evolution in surgical patterns for TED was observed after teprotumumab approval. Notable trends included decreased orbital decompressions, otolaryngologists performing proportionately more decompressions, and increased endoscopic approaches.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"522-529"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bicanalicular canaliculitis.","authors":"Mohammad Javed Ali","doi":"10.1080/01676830.2025.2454357","DOIUrl":"10.1080/01676830.2025.2454357","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"685"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on the innovation of surgery for recurrent naso-orbital mucous cysts.","authors":"Ran Xiong, Long Chen","doi":"10.1080/01676830.2025.2479743","DOIUrl":"10.1080/01676830.2025.2479743","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"656"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Subperiosteal abscess of the orbit with multiple abscesses in the brain and body due to <i>Chromobacterium violaceum</i> sepsis in an infant: a case report and review of the literature.","authors":"Uprimporn Suthiwong, Patcharaporn Chandraparnik","doi":"10.1080/01676830.2025.2462623","DOIUrl":"10.1080/01676830.2025.2462623","url":null,"abstract":"<p><p><i>Chromobacterium violaceum</i> is a rare pathogen known to cause severe, life-threatening infections in humans. Its typical clinical presentations include skin and soft tissue infections, fulminant septicemia, multiple visceral abscesses, and diarrhea. We report the case of a 2-month-old male infant who initially presented with acute fever and subsequently developed acute proptosis of the right eye, accompanied by a palpable mass in the right mastoid area. Computed tomography (CT) scans of the orbits, paranasal sinuses and brain revealed a subperiosteal abscess at the right sphenoid wing, right otomastoiditis, and multiple intracerebral abscesses. Moreover, ultrasonography of the whole abdomen showed multiple liver abscesses. Blood culture analysis confirmed the presence of <i>Chromobacterium violaceum</i>, while comprehensive testing for underlying immunodeficiency returned negative results. The patient's condition was effectively managed through timely surgical intervention, including lateral orbitotomy for pus drainage, combined with appropriate antibiotic treatment. After completing the prescribed course of prophylactic antibiotics, the patient remained free from disease recurrence and showed sustained clinical recovery.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"598-601"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}