Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery最新文献

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Human papilloma virus (HPV) presence in primary tumors of the lacrimal sac: a case series and review of the literature. 泪囊原发性肿瘤中的人乳头状瘤病毒(HPV):病例系列和文献综述。
IF 0.9
Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-04-01 Epub Date: 2024-06-24 DOI: 10.1080/01676830.2024.2370056
Rafael Boucher, Oscar Haigh, Emmanuel Racy, Corinne Bordonne, Emmanuel Barreau, Antoine Rousseau, Marc Labetoulle
{"title":"Human papilloma virus (HPV) presence in primary tumors of the lacrimal sac: a case series and review of the literature.","authors":"Rafael Boucher, Oscar Haigh, Emmanuel Racy, Corinne Bordonne, Emmanuel Barreau, Antoine Rousseau, Marc Labetoulle","doi":"10.1080/01676830.2024.2370056","DOIUrl":"10.1080/01676830.2024.2370056","url":null,"abstract":"<p><p>Primary tumors of the lacrimal sac (PTLS) are a rare subtype of ocular adnexa tumors, with potentially life-threatening clinical course. There has been growing evidence of human papilloma virus (HPV) as an etiological agent in these tumors.In this retrospective observational case series, we report three cases of PTLS. All three underwent an initial dacryocystorhinostomy revealing a tissular mass in the lacrimal sac. Histological findings were respectively epithelial papilloma, epithelial Malpighian papilloma, and undifferentiated epidermoid carcinoma. PCR evaluation identified HPV serotype 6 in the first case and 16 in the third, and high p16 expression was found in the second case.These three cases of PTLS with HPV detection complement 36 other cases identified in the literature, further incriminating HPV in the pathogenesis of these neoplasms. Ophthalmologists must remain wary of chronic lacrimal occlusion symptoms, and resort to CT scan and orbital Doppler sonography whenever first-line treatment fails.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"236-245"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141447348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unusual orbital, scleral and choroidal findings in Erdheim-Chester disease: a case report. Erdheim-Chester 病的眼眶、巩膜和脉络膜异常发现:病例报告。
IF 0.9
Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-04-01 Epub Date: 2024-07-08 DOI: 10.1080/01676830.2024.2373791
M Meyers, I Vermeiren, A Dendooven, N Lauwers, J Goemaere
{"title":"Unusual orbital, scleral and choroidal findings in Erdheim-Chester disease: a case report.","authors":"M Meyers, I Vermeiren, A Dendooven, N Lauwers, J Goemaere","doi":"10.1080/01676830.2024.2373791","DOIUrl":"10.1080/01676830.2024.2373791","url":null,"abstract":"<p><p>This case report highlights a unique presentation of Erdheim-Chester Disease (ECD) with bilateral scleral lesions, choroidal infiltration, and extensive sinus involvement. It is the first case report where the diagnosis was confirmed through a scleral biopsy after an initial presentation of a unilateral nodular scleritis. There was a gradual disease progression and ocular examination later revealed bilateral subconjunctival hyperemic lesions and mild exophthalmos, ophthalmoplegia, and extensive choroidal infiltration. Infiltration of the frontal and maxillary sinus was present and extended into the nasal cavity and both orbits. The diagnostic work-up is described in detail. Current treatment options are analyzed. It is emphasized that the ophthalmologist can play a crucial role in the diagnosis of ECD, given the substantial prevalence of orbital and ocular symptoms. The overall prognosis for ECD remains unfavorable, particularly in cases with orbital involvement. This case underscores the complexity and importance of a multidisciplinary approach in managing ECD.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"246-251"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Orbital-centric invasive aspergillosis with infraorbital nerve enlargement in an immunocompetent patient: a case report.
IF 0.9
Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-03-26 DOI: 10.1080/01676830.2025.2481930
Abdulmajeed S Alkharashi, Ali Yaseen, Hind M Alkatan, Mostafa M Diab, Adel H Alsuhaibani
{"title":"Orbital-centric invasive aspergillosis with infraorbital nerve enlargement in an immunocompetent patient: a case report.","authors":"Abdulmajeed S Alkharashi, Ali Yaseen, Hind M Alkatan, Mostafa M Diab, Adel H Alsuhaibani","doi":"10.1080/01676830.2025.2481930","DOIUrl":"https://doi.org/10.1080/01676830.2025.2481930","url":null,"abstract":"<p><p>Orbital aspergillosis is a rare but potentially life- and sight-threatening fungal infection that can affect both immunocompromised and healthy individuals. We present a case of orbital aspergillosis with infraorbital nerve enlargement in a healthy 30-year-old male who presented with progressive proptosis, diplopia, and vision decline. Nasal endoscopy was unremarkable. CT imaging revealed an ill-defined, infiltrative, hyperdense mass in the left inferior orbital region with presumed enlargement of the infraorbital nerve (ION) and expansion of the ION canal, along with pterygopalatine fossa involvement, while the sinuses were almost clear. MRI showed similar findings. Histopathological analysis confirmed <i>Aspergillus fumigatus</i>. Treatment with voriconazole led to significant clinical improvement. This case underscores the diagnostic challenges of orbital aspergillosis and highlights that ION enlargement should be cautiously interpreted as a specific sign of IgG4-related disease. It is crucial to maintain a high index of suspicion in cases of progressive proptosis, even in the absence of clear sinonasal involvement.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-5"},"PeriodicalIF":0.9,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oculoplastic complications in patients with adenoviral keratoconjunctivitis.
IF 0.9
Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-03-26 DOI: 10.1080/01676830.2025.2481935
Niko J Viskari, Minna H Vesaluoma, Juho O Wedenoja, Marita S Uusitalo
{"title":"Oculoplastic complications in patients with adenoviral keratoconjunctivitis.","authors":"Niko J Viskari, Minna H Vesaluoma, Juho O Wedenoja, Marita S Uusitalo","doi":"10.1080/01676830.2025.2481935","DOIUrl":"https://doi.org/10.1080/01676830.2025.2481935","url":null,"abstract":"<p><strong>Purpose: </strong>Adenoviruses and other viral superficial eye infections may cause long-lasting complications, including conjunctival scarring, synechiae, and lacrimal system obstructions. However, their incidence is not established. Here, we set out to assess possible oculoplastic complications and need for surgical procedures in patients with adenoviral conjunctivitis.</p><p><strong>Methods: </strong>This Finnish register-based retrospective study includes patients with adenoviral conjunctivitis treated at Helsinki University Hospital eye clinic, Finland, during adenoviral outbreak in the winter 2017-2018. Of these identified 168 patients, with median age of 43 years (range 0-83 years), 92 were female and 76 were male. 134 patients presented with a bilateral and 34 with a unilateral disease. Viral cell cultures revealed adenovirus serotypes 4 and 8. The medical records were reviewed in 2021-2022 to assess any oculoplastic complications and related surgical procedures.</p><p><strong>Result: </strong>After adenoviral infection, two patients presented with chronic tearing and were diagnosed with canalicular obstruction. One was primarily treated with silicone tube intubation. The canalicular obstruction of the other patient was released by lacrimal irrigation only, after which the patient remained symptom free. No other oculoplastic complications were found.</p><p><strong>Conclusions: </strong>Adenoviral conjunctivitis with even severe inflammation of the anterior segment rarely causes oculoplastic complications requiring surgical interventions.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-5"},"PeriodicalIF":0.9,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on the innovation of surgery for recurrent naso-orbital mucous cysts. 对复发性鼻眶粘液囊肿手术创新的评论。
IF 0.9
Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-03-21 DOI: 10.1080/01676830.2025.2479743
Ran Xiong, Long Chen
{"title":"Comment on the innovation of surgery for recurrent naso-orbital mucous cysts.","authors":"Ran Xiong, Long Chen","doi":"10.1080/01676830.2025.2479743","DOIUrl":"https://doi.org/10.1080/01676830.2025.2479743","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1"},"PeriodicalIF":0.9,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of bilateral orbital haemorrhages following periocular acupuncture.
IF 0.9
Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-03-21 DOI: 10.1080/01676830.2025.2479745
Amelia E Davidson, Haya Al-Ani, Richard Hart
{"title":"A case of bilateral orbital haemorrhages following periocular acupuncture.","authors":"Amelia E Davidson, Haya Al-Ani, Richard Hart","doi":"10.1080/01676830.2025.2479745","DOIUrl":"https://doi.org/10.1080/01676830.2025.2479745","url":null,"abstract":"<p><p>Acupuncture has been practised for more than 2500 years in the Western Pacific Region and has become an important component of complementary medicine. Acupuncture technique involves the insertion of fine needles into the body at specific points to affect functional changes in internal organ systems. Periocular acupuncture is increasingly used to treat ophthalmologic and non-ophthalmologic conditions. Although there are reported benefits, there is a lack of high-quality evidence supporting its efficacy. There are also increasing reports of complications, including orbital haemorrhage, globe perforation, retinal detachment and endophthalmitis. Here, we present a case of bilateral orbital haemorrhages from periocular acupuncture, highlighting the potential dangers of this practice.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-5"},"PeriodicalIF":0.9,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hybrid neurofibroma-schwannoma of the orbit: a case report and review of the literature.
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Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-03-17 DOI: 10.1080/01676830.2025.2475828
Modupe O Adetunji, Nishita T Sheth, Irene T Lee, Emily T Smith, Jessica L Houk, Julie A Woodward, Thomas J Cummings, Christopher R Dermarkarian
{"title":"Hybrid neurofibroma-schwannoma of the orbit: a case report and review of the literature.","authors":"Modupe O Adetunji, Nishita T Sheth, Irene T Lee, Emily T Smith, Jessica L Houk, Julie A Woodward, Thomas J Cummings, Christopher R Dermarkarian","doi":"10.1080/01676830.2025.2475828","DOIUrl":"https://doi.org/10.1080/01676830.2025.2475828","url":null,"abstract":"<p><p>Hybrid peripheral nerve sheath tumor is a rare tumor subtype that infrequently occurs within the orbit. A 50-year-old male presented with a 6-year history of worsening left-sided proptosis and hypoglobus. Magnetic resonance imaging of the orbits revealed a left superior extraconal, muti-lobulated orbital lesion with extension into the left orbital apex originating from the left frontal nerve. The patient underwent surgical resection of the mass via a left orbito-cranial approach. Histopathologic examination was positive for orbital hybrid neurofibroma-schwannoma. Postoperatively, the patient had improvement in proptosis, resolution of symptoms, and improved cosmesis. This case represents the eleventh reported occurrence of orbital hybrid neurofibroma-schwannoma.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-6"},"PeriodicalIF":0.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nationwide orbital decompression volume, surgical approach, and subspecialty distribution patterns within the center for medicare and medicaid services population in the era of teprotumumab.
IF 0.9
Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-03-13 DOI: 10.1080/01676830.2025.2475844
Daniel B Azzam, Alicia Casella, Yi Ling Dai, M Reza Vagefi
{"title":"Nationwide orbital decompression volume, surgical approach, and subspecialty distribution patterns within the center for medicare and medicaid services population in the era of teprotumumab.","authors":"Daniel B Azzam, Alicia Casella, Yi Ling Dai, M Reza Vagefi","doi":"10.1080/01676830.2025.2475844","DOIUrl":"https://doi.org/10.1080/01676830.2025.2475844","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate nationwide practice patterns in orbital decompression surgery for thyroid eye disease (TED) after approval of teprotumumab in January 2020.</p><p><strong>Methods: </strong>This retrospective study analyzed the Centers for Medicare and Medicaid Services (CMS) database before (2016-2019) and after teprotumumab approval (2020-2023). External (CPT codes 67414 and 67445) and endoscopic (CPT 31292 and 31293) approaches were included. Controls were cataract surgery (CPT 66984) and upper blepharoplasty (CPT 15822 and 15823). Main outcomes were orbital decompression volume, surgical approach, and subspecialty distribution.</p><p><strong>Results: </strong>In total 4,534 orbital decompressions were billed to CMS from 2016 to 2023. Nationwide orbital decompression volume significantly declined (-37%, <i>p</i> < 0.001) in the post-teprotumumab period, even when controlling relative to cataract surgery (<i>p</i> < 0.001) or upper blepharoplasty (<i>p</i> = 0.010). This was attributed to decreased external orbital decompressions (-41%, <i>p</i> < 0.001), while endoscopic approach was less impacted (-28%, <i>p</i> = 0.007). Specialty distribution trended away from oculofacial plastic surgeons (-10%) toward otolaryngologists (+18%) (<i>p</i> < 0.001). The proportion of endoscopic approach significantly grew (+13%, <i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>A nationwide evolution in surgical patterns for TED was observed after teprotumumab approval. Notable trends included decreased orbital decompressions, otolaryngologists performing proportionately more decompressions, and increased endoscopic approaches.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-8"},"PeriodicalIF":0.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Total meibomian gland loss in Parkinson's disease.
IF 0.9
Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-03-13 DOI: 10.1080/01676830.2025.2475840
Prajakta Dandekar, Swati Singh
{"title":"Total meibomian gland loss in Parkinson's disease.","authors":"Prajakta Dandekar, Swati Singh","doi":"10.1080/01676830.2025.2475840","DOIUrl":"https://doi.org/10.1080/01676830.2025.2475840","url":null,"abstract":"<p><p>Parkinson's disease is characterized by motor dysfunction, affecting blink frequency in the eyes. Reduced blinking and use of anticholinergic medications result in dry eye disease (DED) in these patients. This unique case had complete meibomian gland loss seen on meibography with reduced blinking and lacrimal gland function as well attributed to Parkinson's and its treatment. The autoimmune workup was negative, and the final diagnosis of drug-induced DED was made. The patient was managed with ocular lubricants and anti-inflammatory eye drops.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-3"},"PeriodicalIF":0.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The von Gräfe sign measurement. von Gräfe 信号测量。
IF 0.9
Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-03-13 DOI: 10.1080/01676830.2025.2475823
Juliana A Guimaraes, Denny M Garcia, Antonio Augusto V Cruz
{"title":"The von Gräfe sign measurement.","authors":"Juliana A Guimaraes, Denny M Garcia, Antonio Augusto V Cruz","doi":"10.1080/01676830.2025.2475823","DOIUrl":"https://doi.org/10.1080/01676830.2025.2475823","url":null,"abstract":"<p><strong>Purpose: </strong>To measure the amplitude of upper eyelid saccadic movements in patients with Graves' retraction.</p><p><strong>Methods: </strong>The amplitude and velocity of lid saccades were quantified using customized software in 36 patients with Graves' upper eyelid retraction (GO) and in 32 subjects of a control group (CG). All patients were in the chronic phase of the disease and had a controlled thyroid status. Eyelid retraction was measured using the software ImageJ. Levator palpebrae superioris muscle (LPSM) dimensions were measured through orbital computed tomography (CT).</p><p><strong>Results: </strong>The mean MRD1 was 6.5 mm and 3.9 mm in the GO and CG groups, respectively. The LPSM was radiologically enlarged in patients. The absolute values of both amplitude and velocity of lid movement did not differ between the two groups. However, considering the final position of the lid margin in relation to the pupil in downgaze, the margin-reflex distance of the patients was significantly higher than that of the controls.</p><p><strong>Conclusion: </strong>In patients with upper eyelid retraction in inactive GO the relaxation of the LPSM are not affected, despite the muscle enlargement. However, the amplitude of the downward lid movement of the patients does not compensate for the lid retraction. The final position of the lid margin of the patients in downgaze is significantly higher than in controls, indicating the inability of the LPMS relaxation to overcome lid retraction. The von Gräfe sign is thus a relative phenomenon and not an absolute indication of loss of the lid elastic properties.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-6"},"PeriodicalIF":0.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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