{"title":"Letter to the editor regarding the article \"The effect of traction force on eyelid blood perfusion during closure of defects\".","authors":"Fernando Procianoy","doi":"10.1080/01676830.2024.2371005","DOIUrl":"10.1080/01676830.2024.2371005","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"252"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Wiktorin, Elin Bohman, John Albinsson, Rafi Sheikh, Malin Malmsjö
{"title":"Cryosurgery of eyelid actinic keratosis and the effect of adrenaline in local anesthetics - temperature mapping using IR thermography.","authors":"Anna Wiktorin, Elin Bohman, John Albinsson, Rafi Sheikh, Malin Malmsjö","doi":"10.1080/01676830.2024.2403464","DOIUrl":"10.1080/01676830.2024.2403464","url":null,"abstract":"<p><strong>Purpose: </strong>The efficacy of cryosurgery is believed to depend on the thaw time. The presence of adrenaline in local anesthetics affects blood perfusion, and may thus also affect the thaw time. The aim of the present study was to use IR thermography to monitor the tissue temperature during cryosurgery of actinic keratosis, and to assess the effect of adrenaline in local anesthetics.</p><p><strong>Methods: </strong>Twelve patients with actinic keratosis in the periorbital region underwent cryosurgery. The temperature was continuously mapped using a high-precision IR camera and was also visually assessed by the surgeon. The results obtained when employing local anesthetics with and without adrenaline were compared.</p><p><strong>Results: </strong>The temperature change during thawing showed a triphasic pattern. The thaw time was significantly longer when using an anesthetic with adrenaline. This was observed with both IR thermography and by visual observation.</p><p><strong>Conclusions: </strong>The findings indicate that a longer freezing time may be needed when using a local anesthetic without adrenaline to achieve the same cryo-effect as when using a local anesthetic with adrenaline. A larger clinical trial is needed on the effects of using local anesthetics with and without adrenaline to treat actinic keratosis, for example, the clearance rate, before recommendations can be made concerning their use.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"171-177"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara L Hojjatie, Nicholas Radulovich, Alexa Van Brummen, Christopher Chambers, Roxana Fu, Rhonda Mittenzwei, Matthew M Zhang
{"title":"A case of necrotizing fasciitis of the orbit secondary to <i>Aspergillus fumigatus</i> and mixed flora.","authors":"Sara L Hojjatie, Nicholas Radulovich, Alexa Van Brummen, Christopher Chambers, Roxana Fu, Rhonda Mittenzwei, Matthew M Zhang","doi":"10.1080/01676830.2024.2353235","DOIUrl":"10.1080/01676830.2024.2353235","url":null,"abstract":"<p><p>A 79-year-old female presented to the emergency department for sudden-onset ocular pain, edema, and erythema around her left eye. She also had a left-sided migraine and frontal fullness for 2 weeks. She had attentive care for the diagnosis of orbital cellulitis and prompt recognition of necrotizing fasciitis. Wound cultures were positive for over 5 strains of bacteria in addition to <i>Aspergillus</i>. In a combined effort by our institution's Ophthalmology and Otolaryngology departments, the patient was successfully treated with debridement, porcine bladder matrix, antibiotics, and antifungals. The authors describe the first reported case of eyelid and periorbital necrotizing fasciitis, caused by mixed flora and <i>Aspergillus fumigatus</i>, that showed promising wound healing with the outlined treatment paradigm.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"207-210"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael K Yoon, Victor D Liou, Mišo Gostimir, Makayla M McCoskey
{"title":"Foreign body suture granuloma in canthal surgery: association with suture type.","authors":"Michael K Yoon, Victor D Liou, Mišo Gostimir, Makayla M McCoskey","doi":"10.1080/01676830.2024.2404678","DOIUrl":"10.1080/01676830.2024.2404678","url":null,"abstract":"<p><strong>Purpose: </strong>Foreign body suture reaction (\"suture granuloma\") is a complication faced by all surgeons. The purpose of this study was to examine the incidence and risk factors of suture granulomas in canthal surgery.</p><p><strong>Methods: </strong>An IRB-approved retrospective review of medical records identified patients who had canthal surgery. Statistical analysis was performed on multiple data points to determine associations with granuloma formation. Summary statistics were reported as a mean and standard deviation for continuous variables, and as frequencies or proportions for categorical variables. Effect estimates were reported as odds ratios. A <i>p</i>-value of less than .05 was deemed statistically significant.</p><p><strong>Results: </strong>A total of 758 procedures were included. Seven commonly used suture materials were encountered including uncoated polyester, polyester coated with polytetramethylene adipate (PTMA), nylon, polydioxanone, polyester coated with polytetrafluoroethylene (PTFE), polypropylene, and polyglactin 910. Eighteen total granulomas were observed (2.4%). Fifteen granulomas were associated with uncoated polyester, two with polyester coated with PTFE, and one with polypropylene. The odds of developing a suture granuloma with uncoated polyester were 25.4 times as likely as polyglactin 910 (<i>p</i> = .04). The odds of developing a suture granuloma with a non-absorbable, braided suture were 23.2 times as likely as absorbable, braided suture (<i>p</i> = .04). There was no significant association identified between the other collected variables.</p><p><strong>Conclusions: </strong>Foreign body suture granulomas occur at a low rate following canthal surgery and can be largely avoided through careful selection of resorbable or monofilament sutures.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"185-189"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142336894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jessica X L Li, Eve Slavich, Raymond Sacks, Minas Coroneo, Geoffrey Wilcsek
{"title":"Retrospective cohort study of self-reported outcomes after unilateral dacryocystorhinostomy in patients with bilateral epiphora and suspected nasolacrimal obstruction.","authors":"Jessica X L Li, Eve Slavich, Raymond Sacks, Minas Coroneo, Geoffrey Wilcsek","doi":"10.1080/01676830.2024.2404671","DOIUrl":"10.1080/01676830.2024.2404671","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to quantify the proportion of patients with bilateral epiphora and suspected nasolacrimal obstruction who self-reported improved epiphora bilaterally following unilateral dacryocystorhinostomy and investigate predictive factors.</p><p><strong>Methods: </strong>A retrospective cohort study of patients from an Australian lacrimal clinic was performed. Eligible patients were at least 18 years of age, complained of bilateral epiphora, underwent unilateral dacryocystorhinostomy between 2012 and 2022 and followed-up. Outcome groups were created by grouping self-reported epiphora improvement levels for each eye. Two-sided confidence intervals were calculated for the proportion of participants in each outcome group. Ordinal elastic net regression identified clinical features associated with outcome groups and estimated their effect sizes.</p><p><strong>Results: </strong>Of 243 patients, the median post-operative follow-up duration was 3 months. Fifty-eight percent (95% CI 52-64%, <i>n</i> = 141) reported significant improvement (≥50% ipsilateral and any contralateral improvement), 5% (95% CI 3-9%, <i>n</i> = 13) reported small improvement (<50% ipsilateral and any contralateral improvement) and 26% (95% CI 20-31%, <i>n</i> = 62) reported ipsilateral improvement only. Eleven percent had functional or anatomical failure. Older age (OR 1.01), contralateral nasolacrimal duct narrowing (OR 1.37), contralateral nasolacrimal duct obstruction (OR 0.93) and longer follow-up time (OR 0.85) predicted outcome groups.</p><p><strong>Conclusions: </strong>After unilateral DCR, many patients with bilateral epiphora and suspected nasolacrimal obstruction report an improvement of their symptoms bilaterally in the early postoperative period. Contralateral nasolacrimal system diagnosis, patient age and follow-up duration were associated with outcomes. Further study using validated epiphora assessment tools may quantify this observation, and we suggest a potential underlying mechanism of contralateral effects after unilateral treatment.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"178-184"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142336895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sandy Zhang-Nunes, Joy Li, Jill Foster, Cameron Nabavi, Daniel Straka, Kenneth Cahill, Vishal Patel
{"title":"Ultrahigh field (7T) MRI for assessment of orbitofacial structures.","authors":"Sandy Zhang-Nunes, Joy Li, Jill Foster, Cameron Nabavi, Daniel Straka, Kenneth Cahill, Vishal Patel","doi":"10.1080/01676830.2021.2011327","DOIUrl":"10.1080/01676830.2021.2011327","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":"1 1","pages":"254"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59751298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adam R Sweeney, Christopher R Dermarkarian, Katherine J Williams, Richard C Allen, Michael T Yen
{"title":"Recurrence following ptosis repair surgery: a multivariate analysis of risk factors.","authors":"Adam R Sweeney, Christopher R Dermarkarian, Katherine J Williams, Richard C Allen, Michael T Yen","doi":"10.1080/01676830.2024.2396373","DOIUrl":"10.1080/01676830.2024.2396373","url":null,"abstract":"<p><strong>Purpose: </strong>To identify and evaluate the risk factors for ptosis repair failure.</p><p><strong>Methods: </strong>Retrospective, case-controlled study evaluating adult patients with ptosis who underwent ptosis surgery by external levator advancement/resection (ELR) or Müller muscle conjunctival resection (MMCR) with at least 3 months postoperative follow-up. Regression analyses were performed of ptosis repair outcomes comparing preoperative and perioperative risk factors for failure.</p><p><strong>Results: </strong>A total of 240 patients (404 eyelids) met the inclusion criteria for the study. Surgical outcomes were measured categorically by success rate and measured quantitively over time using Kaplan-Meier survival analysis. Success was categorically achieved in 101/112 (90%) eyelids after MMCR and 231/292 (79%) eyelids after ELR (<i>p</i> = .0088). Success as measured over 5 years of follow-up was significantly better in eyelids following MMCR compared to ELR (<i>p</i> = .0469). In terms of surgical failure, the following variables were found to be predictive in order of decreasing risk: chronic topical prostaglandin use, chronic topical corticosteroid use, surgical approach, lower preoperative margin reflex distance 1, prior intraocular surgery, age, lower preoperative levator function, concomitant blepharoplasty, presence of a glaucoma filtering bleb, and female gender.</p><p><strong>Conclusions: </strong>Ptosis repair surgery is a complex and challenging procedure. This study provides the largest comparative analysis of ELR versus MMCR to date with findings suggesting MMCR to be more a successful surgery than ELR. Topical prostaglandin analogue use appears to be the highest known risk factor for MMCR and ELR ptosis repair failure.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"154-162"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142120907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eyelid skin and fibroadipose tissue MMP-1, MMP-3, TNF-α, and IL-6 levels in patients with inactive moderate-to-severe Graves' orbitopathy.","authors":"Nilay Yuksel, Ummuhani Ozel-Turkcu, Muslum Gok, Ozge Saritas, Bulent Yazici","doi":"10.1080/01676830.2024.2414770","DOIUrl":"10.1080/01676830.2024.2414770","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate matrix metalloprotease-1 (MMP-1), matrix metalloprotease-3 (MMP-3), tumor necrosis factor alpha (TNF-α), and interleukin-6 (IL-6) levels in the eyelid skin and fibroadipose tissue in patients with inactive moderate-to-severe Graves' orbitopathy (GO).</p><p><strong>Methods: </strong>This prospective study included 23 patients with inactive moderate-to-severe GO who underwent upper blepharoplasty and medial fat excision, and 22 age- and sex-matched healthy subjects. MMP-1, MMP-3, TNF-α, and IL-6 levels in the skin and fibroadipose tissue obtained during surgery were measured using the ELISA method.</p><p><strong>Results: </strong>The mean MMP-1 level in the eyelid skin (<i>p</i> = .003) and the mean MMP-3 level in the fibroadipose tissue (<i>p</i> = .04) were significantly lower in the GO group compared to the healthy control group. There were no differences in other mediators in both tissues between the two groups (<i>p</i> > .05).</p><p><strong>Conclusions: </strong>The lower levels of proteolytic enzymes such as MMP-1 and MMP-3 in the eyelid skin and orbital fibroadipose tissue of patients with chronic inactive GO may play a role in the increase of collagen and glycosaminoglycans in orbital soft tissues.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"190-195"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jens Nääv Ottosson, Johanna V Berggren, Kajsa Tenland, Elin Bohman, Rafi Sheikh, Malin Malmsjö, Aboma Merdasa
{"title":"Reply Re: \"The effect of traction force on eyelid blood perfusion during closure of defects\".","authors":"Jens Nääv Ottosson, Johanna V Berggren, Kajsa Tenland, Elin Bohman, Rafi Sheikh, Malin Malmsjö, Aboma Merdasa","doi":"10.1080/01676830.2024.2375305","DOIUrl":"10.1080/01676830.2024.2375305","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"253"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fatty infiltration of extraocular muscles on magnetic resonance imaging.","authors":"Khizar Rana, Shubham Tiwari, Liwen Seto, Amber Kraczkowska, Sandy Patel, Minh-Son To, Dinesh Selva","doi":"10.1080/01676830.2024.2391909","DOIUrl":"10.1080/01676830.2024.2391909","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the prevalence of fatty infiltration in normal orbits using magnetic resonance imaging (MRI) and its impact on muscle diameters.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on normal orbits in patients who underwent coronal T1-weighted MRI. Fatty infiltration was defined by a hyperintense signal within the extraocular muscle. Fatty infiltration area was calculated by dividing the cross-sectional fat area by the sum of the muscle and fat area in the coronal plane. Muscle diameters were measured perpendicular to the muscle belly at their maximum and the mean diameters of the infiltrated muscles were compared with the non-infiltrated muscles.</p><p><strong>Results: </strong>Seventy-six orbits from 76 participants with a mean age of 55.7 ± 18 years were included. Fatty infiltration in at least one muscle was seen in 57 (75%) of participants. When infiltration was present, inferior rectus was most commonly involved (98%). The area of fatty infiltration ranged from 6% to 42%, with 5 participants in the <10% group, 36 in the 10-20% group, 20 in the 20-30% group, 9 in the 30-40% group and 2 in the 40-50% group. Participants with fatty infiltration were significantly older (mean 61 ± 15 years vs 40 ± 16 years, <i>p</i> < .01) and had a higher proportion of males (56% vs 16%, <i>p</i> < .01). No significant difference in muscle diameters were found between infiltrated and healthy muscles.</p><p><strong>Conclusion: </strong>Fatty infiltration of the extraocular muscles is a reasonably common finding in normal orbits, most commonly involves the inferior rectus muscle and is associated with increasing age.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"145-149"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}