Paulina Truong, Saif Aldeen Alryalat, Osama Al Deyabat, Andrew G Lee, Patricia Chévez-Barrios, Amina Malik
{"title":"Necrosis of pleomorphic adenoma of the lacrimal gland with acute and chronic arteriolar occlusion.","authors":"Paulina Truong, Saif Aldeen Alryalat, Osama Al Deyabat, Andrew G Lee, Patricia Chévez-Barrios, Amina Malik","doi":"10.1080/01676830.2025.2449988","DOIUrl":"10.1080/01676830.2025.2449988","url":null,"abstract":"<p><p>Pleomorphic adenoma of the lacrimal gland (PALG) is a benign neoplasm typically presenting with gradual, painless globe displacement and/or lid swelling. We report an atypical case of PALG in a 53-year old male presenting acutely, mimicking orbital cellulitis. Imaging demonstrated an extraconal rim-enhancing soft-tissue lesion medial to the left lacrimal gland, involving superior rectus and levator palpebrae superioris. Surgical excision and histopathology revealed PALG with central infarction, necrosis, and chronic and acute pseudocapsular arteriolar occlusion. These findings correlated with the fluctuating symptoms and suggested a multifactorial mechanism involving both underlying vasculopathy, thrombosis, and tumor growth. Infarction in PALG may occur iatrogenically or from spontaneous tumor infarction, and can cause an acute inflammatory presentation. We discuss unique histopathologic features of necrotic PALG and mechanisms of infarction. Recognition of these features and the varied presentations of PALG is crucial for proper diagnosis. Complete resection is necessary to prevent recurrence or malignant transformation.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"592-597"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Margaret B Mitchell, Ryan Bartholomew, Angela Zhu, Benjamin Bleier, Barak Ringel
{"title":"Artificial intelligence based semi-automatic segmentation for orbital tumor preoperative modeling.","authors":"Margaret B Mitchell, Ryan Bartholomew, Angela Zhu, Benjamin Bleier, Barak Ringel","doi":"10.1080/01676830.2025.2470359","DOIUrl":"10.1080/01676830.2025.2470359","url":null,"abstract":"<p><strong>Purpose: </strong>With the increasing utilization of endoscopic approaches for primary benign orbital tumor (PBOT) surgery, otolaryngologists and ophthalmologists are challenged with determining candidacy for endoscopic resection based on preoperative imaging. Our objective was to develop a semi-automatic modality for three-dimensional reconstruction of primary benign orbital tumors to shed light on their resectability.</p><p><strong>Methods: </strong>Patients with tumors from each ORBIT (Orbital Resection by Intranasal Technique) class were identified. Patients' preoperative imaging was obtained, and 3D slicer was utilized to segment the tumor with key anatomical structures, creating a three-dimensional model for each patient.</p><p><strong>Results: </strong>A model was generated for all five ORBIT classes. These models demonstrated the key findings differentiating classes such as whether a tumor is intraconal vs. extraconal, anterior or posterior to the intersection of the ophthalmic artery and optic nerve, or extends into the pterygopalatine and/or infratemporal fossa through inferior orbital fissure or through the superior orbital fissure.</p><p><strong>Conclusion: </strong>Our study utilized 3DSlicer to semi-automatically develop three-dimensional reconstructions of each class of benign orbital tumors as designated by ORBIT criteria. These reconstructions may provide additional quantitative and qualitative data regarding these tumors, their resectability, and the potential surgical approaches required.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"511-515"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexander A Dennis, Delaram Mirzania, Zhenyang Zhao, Scott A McLean, Hakan Demirci, Vinay Aakalu, Christine C Nelson
{"title":"Safety and feasibility of performing sentinel lymph node biopsy for periorbital malignancies at freestanding outpatient surgical centers.","authors":"Alexander A Dennis, Delaram Mirzania, Zhenyang Zhao, Scott A McLean, Hakan Demirci, Vinay Aakalu, Christine C Nelson","doi":"10.1080/01676830.2025.2453972","DOIUrl":"10.1080/01676830.2025.2453972","url":null,"abstract":"<p><strong>Purpose: </strong>Sentinel lymph node biopsy (SLNB) is vital for stratifying and treating facial and periorbital malignancies, but data on SLNB performed in freestanding outpatient surgical centers (OSC) is scarce.</p><p><strong>Methods: </strong>A retrospective review was conducted on 79 consecutive SLNB procedures from September 2014 to November 2022 at an academic hospital (46 cases) and OSCs (33 cases) affiliated with our institution. We compared demographics, clinical characteristics, wait time, operative time, estimated blood loss (EBL), and complications.</p><p><strong>Results: </strong>Patients at OSCs were younger (mean age 62 vs. 73, <i>p</i> < 0.001) and had lower perioperative risk (ASA score 2.18 vs. 2.71, <i>p</i> < 0.001) than those in a hospital setting. SLNB procedures at OSCs were shorter (73 vs. 113 minutes, <i>p</i> < 0.001) with significantly less EBL (11.48 mL vs. 45.53 mL, <i>p</i> = 0.03), and no complications.</p><p><strong>Conclusions: </strong>SLNB procedures for eligible patients are safe and effective when performed at freestanding outpatient surgical centers affiliated with our institution.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"498-503"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdulmajeed S Alkharashi, Ali Yaseen, Hind M Alkatan, Mostafa M Diab, Adel H Alsuhaibani
{"title":"Orbital-centric invasive aspergillosis with infraorbital nerve enlargement in an immunocompetent patient: a case report.","authors":"Abdulmajeed S Alkharashi, Ali Yaseen, Hind M Alkatan, Mostafa M Diab, Adel H Alsuhaibani","doi":"10.1080/01676830.2025.2481930","DOIUrl":"10.1080/01676830.2025.2481930","url":null,"abstract":"<p><p>Orbital aspergillosis is a rare but potentially life- and sight-threatening fungal infection that can affect both immunocompromised and healthy individuals. We present a case of orbital aspergillosis with infraorbital nerve enlargement in a healthy 30-year-old male who presented with progressive proptosis, diplopia, and vision decline. Nasal endoscopy was unremarkable. CT imaging revealed an ill-defined, infiltrative, hyperdense mass in the left inferior orbital region with presumed enlargement of the infraorbital nerve (ION) and expansion of the ION canal, along with pterygopalatine fossa involvement, while the sinuses were almost clear. MRI showed similar findings. Histopathological analysis confirmed <i>Aspergillus fumigatus</i>. Treatment with voriconazole led to significant clinical improvement. This case underscores the diagnostic challenges of orbital aspergillosis and highlights that ION enlargement should be cautiously interpreted as a specific sign of IgG4-related disease. It is crucial to maintain a high index of suspicion in cases of progressive proptosis, even in the absence of clear sinonasal involvement.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"638-642"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Henry Bair, Narmien Murdock, Karine Shebaclo, Mansi Shah, Jacqueline R Carrasco
{"title":"A simplified sutureless Müllerectomy for ptosis repair: a case series.","authors":"Henry Bair, Narmien Murdock, Karine Shebaclo, Mansi Shah, Jacqueline R Carrasco","doi":"10.1080/01676830.2025.2516740","DOIUrl":"10.1080/01676830.2025.2516740","url":null,"abstract":"<p><strong>Purpose: </strong>Müller's muscle-conjunctival resection (MMCR) is a well-established posterior approach to correct mild to moderate ptosis. Traditional methods involve resection of a measured segment of Müller's muscle and conjunctiva, followed by the approximation of resected edges with sutures. In recent years, various sutureless MMCR techniques have been reported. Here, we describe and evaluate a modified sutureless approach that eliminates the need for specialized instruments.</p><p><strong>Methods: </strong>A retrospective case series was conducted to evaluate outcomes of patients who underwent sutureless MMCR ptosis repair. All surgeries were performed by one surgeon. For the procedure itself, curved hemostats were used to delineate and clamp the measured amount of Müller's muscle and conjunctiva, which were then resected and cauterized. Surgical outcomes, including margin reflex distance (MRD1) improvement, symmetry, and complications, were analyzed.</p><p><strong>Results: </strong>A total of 105 eyelids from 66 adult patients who underwent sutureless MMCR were included in this study. Fifty eyelids (47.6%) underwent concurrent procedures such as blepharoplasty and internal browpexy. The mean increase in MRD1 was 3.31 mm in the entire cohort and 2.76 mm in the MMCR-alone cohort. Symmetry within 1 mm was achieved in 96% of bilateral cases. Post-operative complications were limited to foreign body sensation in five patients and pyogenic granuloma in one patient. One patient required revision with external ptosis repair.</p><p><strong>Conclusions: </strong>The modified sutureless MMCR described here is a simple, effective, and safe technique for ptosis repair, either in isolation or with concomitant eyelid and brow procedures, providing excellent outcomes with minimal potential complications.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"578-583"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tiffany S Cheng, Tatyana Milman, Charlotte L Marous
{"title":"Symblepharon induced giant conjunctival cyst.","authors":"Tiffany S Cheng, Tatyana Milman, Charlotte L Marous","doi":"10.1080/01676830.2025.2565803","DOIUrl":"https://doi.org/10.1080/01676830.2025.2565803","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145207800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Judy Gaffar, Victoria Leung, André Chollet, Elie Boghossian, Vijayabalan Balasingam, Pascal Lavergne, Evan Kalin-Hajdu
{"title":"Eyelid and conjunctiva sparing exenteration followed by microvascular free flap reconstruction - report of two cases.","authors":"Judy Gaffar, Victoria Leung, André Chollet, Elie Boghossian, Vijayabalan Balasingam, Pascal Lavergne, Evan Kalin-Hajdu","doi":"10.1080/01676830.2025.2566458","DOIUrl":"https://doi.org/10.1080/01676830.2025.2566458","url":null,"abstract":"<p><p>Eyelid and conjunctiva sparing exenteration (ECSE) allows for the extirpation of pathologies that lie deep within the orbit without disrupting the anatomy of the eyelids. Despite the cosmetic benefits of maintaining the eyelids, few cases of ECSE have been reported, and reconstruction following the procedure has only been detailed in the form of primary closure or a temporalis muscle transfer. The authors present two patients with deep orbital pathologies that extended into the intracranial space. Each patient underwent an extended ECSE followed by reconstruction with a microvascular free flap. The combination of ECSE plus microvascular free flap reconstruction offers an alternative approach to previously published techniques and may improve esthetic outcomes when exenteration is required for deep orbital pathologies.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-5"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145207817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Modupe O Adetunji, Nishita T Sheth, Irene T Lee, Emily T Smith, Jessica L Houk, Julie A Woodward, Thomas J Cummings, Christopher R Dermarkarian
{"title":"Hybrid neurofibroma-schwannoma of the orbit: a case report and review of the literature.","authors":"Modupe O Adetunji, Nishita T Sheth, Irene T Lee, Emily T Smith, Jessica L Houk, Julie A Woodward, Thomas J Cummings, Christopher R Dermarkarian","doi":"10.1080/01676830.2025.2475828","DOIUrl":"10.1080/01676830.2025.2475828","url":null,"abstract":"<p><p>Hybrid peripheral nerve sheath tumor is a rare tumor subtype that infrequently occurs within the orbit. A 50-year-old male presented with a 6-year history of worsening left-sided proptosis and hypoglobus. Magnetic resonance imaging of the orbits revealed a left superior extraconal, muti-lobulated orbital lesion with extension into the left orbital apex originating from the left frontal nerve. The patient underwent surgical resection of the mass via a left orbito-cranial approach. Histopathologic examination was positive for orbital hybrid neurofibroma-schwannoma. Postoperatively, the patient had improvement in proptosis, resolution of symptoms, and improved cosmesis. This case represents the eleventh reported occurrence of orbital hybrid neurofibroma-schwannoma.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"619-624"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A very rare case: superior rectus intramuscular orbital adnexal lipoma.","authors":"Shruthi Tara V, Rajesh Prabhu V, Pallavi M P, Rishikesh Balvalli","doi":"10.1080/01676830.2025.2483337","DOIUrl":"10.1080/01676830.2025.2483337","url":null,"abstract":"<p><p>Lipomas are common benign mesenchymal tumors, often found in the subcutaneous plane. Deeper lipomas situated in intramuscular or retroperitoneal locations are seen less frequently. Orbital lipomas are sporadic, with an incidence varying from 0% to 11%, whereas extraocular muscle lipoma is rare and accounts for only 0.6%. Despite their infiltrative nature and tendency to recur locally, intramuscular lipomas do not have malignant potential. A review of literature revealed only four cases of extraocular muscle lipomas worldwide. Through this paper, we report an indolent case of superior rectus lipoma and its presentation, appearance, histopathology, differential diagnosis, and management.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"643-648"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Increased severity of ocular and oculofacial injuries in major league baseball after implementation of a pitch clock.","authors":"Sean Teebagy, Grayson Armstrong, Kevin Heinze","doi":"10.1080/01676830.2025.2496764","DOIUrl":"10.1080/01676830.2025.2496764","url":null,"abstract":"<p><strong>Purpose: </strong>Ocular and oculofacial injuries in baseball can lead to significant morbidity, particularly from high-velocity impacts. In 2023, Major League Baseball (MLB) introduced a pitch clock to accelerate the pace of play. This study evaluates whether these rule changes influenced the frequency and severity of oculofacial injuries among MLB players.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on MLB players who sustained ocular and oculofacial trauma resulting in missed games between the 2019 and 2024 seasons. Injuries were categorized anatomically and assessed for association with pitching. Injury severity was measured by the number of days missed. Statistical comparisons between pre-rule (2019-2022) and post-rule (2023-2024) periods were performed using Mann-Whitney U, Chi-square, and Kruskal-Wallis tests.</p><p><strong>Results: </strong>Fifty-six injuries were analyzed. Injury frequency did not significantly change between the pre-rule (8.25 injuries/season, SD ± 2.95) and post-rule periods (11.5 injuries/season, SD ± 1.50; <i>p</i> = .481). Pitching-related injury severity increased significantly, with time missed rising from 3.25 days/injury (SD ± 4.89) pre-rule to 34.64 days/injury (SD ± 73.10; <i>p</i> = 0.001). Periorbital injury severity also increased from 3.31 days/injury (SD ± 5.09) pre-rule to 42.40 days/injury (SD ± 84.98; <i>p</i> = 0.005).</p><p><strong>Conclusion: </strong>While the frequency of oculofacial injuries remained stable, the severity of pitching-related injuries significantly increased following the rule change. Reduced recovery time between plays may contribute to higher-impact trauma. Further investigation and enhanced protective measures are warranted to mitigate potential safety risks.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"561-566"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}