Ghasem Yazdanpanah, Kevin Heinze, Raine Solarin, Thasarat Sutabutr Vajaranant, Pete Setabutr, Ann Q Tran
{"title":"Social vulnerability and reliability to attend clinic appointments in an urban oculoplastic surgery clinic.","authors":"Ghasem Yazdanpanah, Kevin Heinze, Raine Solarin, Thasarat Sutabutr Vajaranant, Pete Setabutr, Ann Q Tran","doi":"10.1080/01676830.2025.2514723","DOIUrl":"https://doi.org/10.1080/01676830.2025.2514723","url":null,"abstract":"<p><strong>Purpose: </strong>The social vulnerability index (SVI) is a community-level scoring system based on US Census tract, designed to assess vulnerability during disasters. Here, we evaluate the relationship of CDC-defined SVI with office visit compliance in an urban oculoplastic surgery clinic.</p><p><strong>Methods: </strong>In this single-center retrospective study, age, gender, race/ethnicity, electronic accessibility status, residential address, and number of completed and no-show visits were collected of individuals treated at an oculoplastic clinic from Sept 2020 to Sept 2023. The 2020 Census Tract SVI scores were obtained using the residential addresses for the overall SVI, four thematic SVIs, and 16 social factors' SVIs. A greater SVI (range 0-1) indicates higher social vulnerability. Categorical, numerical, and logistic regression statistical tests were performed to determine factors predictive of unreliable visit attendance, defined as failure to attend >25% of scheduled appointments.</p><p><strong>Results: </strong>The final analysis included 3,287 patients with a mean age of 52 ± 21 years, 61% of whom were female. In the study period, 787 patients (24%) were found to have unreliable attendance at their scheduled appointments. Having an overall SVI of 0.75 or higher was associated with an increased likelihood of unreliable visit attendance (OR 2.7, 95% CI 2.1-3.5, <i>p</i> < 0.001). Additionally, a thematic SVI of 0.75 or higher regarding racial and ethnic minority status resulted in an increased likelihood of unreliable attendance (OR 2.1, 95% CI 1.2-3.4, <i>p</i> = 0.008).</p><p><strong>Conclusions: </strong>This is the first study showing that living in communities with high SVI scores is associated with poor oculoplastic surgery office visit attendance.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-8"},"PeriodicalIF":0.9,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aline R da Silva, Gabriel M de Oliveira, Patricia M S Akaishi
{"title":"Iatrogenic Horner's syndrome in pediatric patients: a report of two cases and a literature review.","authors":"Aline R da Silva, Gabriel M de Oliveira, Patricia M S Akaishi","doi":"10.1080/01676830.2025.2514724","DOIUrl":"https://doi.org/10.1080/01676830.2025.2514724","url":null,"abstract":"<p><p>Horner's syndrome (HS) is a condition characterized by ptosis, miosis, and facial anhidrosis. The causes include trauma and surgical procedures in the cervical, thoracic, or cranial regions, which can impair sympathetic fibers. In the cases presented, both patients - a infant and an adolescent - developed HS after cervical manipulations. In the first case, a child presented with ptosis and miosis in the right eye following venous puncture in the cervical region, with spontaneous resolution. In the second case, an adolescent developed HS after the removal of the submandibular gland and lymph nodes, presenting with ptosis that required surgical correction. These cases highlight the importance of a comprehensive diagnostic evaluation, including pharmacological tests and imaging studies, to confirm Horner's syndrome and rule out underlying severe causes. The therapeutic approach should be individualized, considering the clinical characteristics of each patient and the potential for recovery from the condition.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-7"},"PeriodicalIF":0.9,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Connor Zuraski, Jin Sook Yoon, Alexander C Lieu, Nicole Topilow, Don Pizzo, Bobby S Korn, Don O Kikkawa, Cole Ferguson, Catherine Y Liu
{"title":"Periostin: a promising biomarker in nonspecific orbital inflammation and orbit-involving IgG4 disease.","authors":"Connor Zuraski, Jin Sook Yoon, Alexander C Lieu, Nicole Topilow, Don Pizzo, Bobby S Korn, Don O Kikkawa, Cole Ferguson, Catherine Y Liu","doi":"10.1080/01676830.2025.2505510","DOIUrl":"https://doi.org/10.1080/01676830.2025.2505510","url":null,"abstract":"<p><strong>Purpose: </strong>To demonstrate crisp, specific immunohistochemistry (IHC) for periostin and document its utility as a biomarker for nonspecific orbital inflammation (NSOI) and immunoglobulin G4-related orbital disease (IgG4-RD).</p><p><strong>Methods: </strong>A multi-institutional retrospective study of both NSOI and IgG4-RD patients. Demographics, clinical disease location, and severity were recorded. Routine histologic sections of affected NSOI and IgG4-RD tissue and fibrocollagenous control tissue were interrogated with an anti-periostin antibody.</p><p><strong>Results: </strong>Ten NSOI patients had orbital manifestations of variable severity involving the lacrimal gland, extraocular muscle, and diffuse or focal orbital tissue. 12 IgG4-RD disease patients had involvement of the lacrimal gland, multifocal orbital disease, or extra-orbital extension. Periostin IHC showed strong, diffuse positivity restricted to pathological fibrotic zones, sparing inflammatory and epithelial elements. This was observed in both the NSOI and IgG4 cases.</p><p><strong>Conclusion: </strong>Periostin is highly expressed in zones of pathologic fibrosis, indicating its potential role in NSOI and IgG4 disease pathogenesis and as a disease biomarker.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-8"},"PeriodicalIF":0.9,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Upasana Pokal, Vijitha S Vempuluru, Saumya Jakati, Swathi Kaliki
{"title":"An unusual cause of a sub-brow lesion.","authors":"Upasana Pokal, Vijitha S Vempuluru, Saumya Jakati, Swathi Kaliki","doi":"10.1080/01676830.2025.2515593","DOIUrl":"https://doi.org/10.1080/01676830.2025.2515593","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1"},"PeriodicalIF":0.9,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Extreme manifestation of congenital nasolacrimal duct obstruction in a neonate.","authors":"Mohammad Javed Ali, Lekshmy Sankar","doi":"10.1080/01676830.2025.2515601","DOIUrl":"https://doi.org/10.1080/01676830.2025.2515601","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1"},"PeriodicalIF":0.9,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vijitha S Vempuluru, Lekshmy Sankar, Swathi Kaliki
{"title":"Vitamin K deficiency resulting in orbital subperiosteal hematoma with massive proptosis.","authors":"Vijitha S Vempuluru, Lekshmy Sankar, Swathi Kaliki","doi":"10.1080/01676830.2025.2515591","DOIUrl":"https://doi.org/10.1080/01676830.2025.2515591","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1"},"PeriodicalIF":0.9,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sierra K Ha, Lisa Y Lin, Min Shi, Mengyu Wang, Ji Yun Han, Nahyoung Grace Lee
{"title":"Deep learning model for differentiating thyroid eye disease and orbital myositis on computed tomography (CT) imaging.","authors":"Sierra K Ha, Lisa Y Lin, Min Shi, Mengyu Wang, Ji Yun Han, Nahyoung Grace Lee","doi":"10.1080/01676830.2025.2510587","DOIUrl":"https://doi.org/10.1080/01676830.2025.2510587","url":null,"abstract":"<p><strong>Purpose: </strong>To develop a deep learning model using orbital computed tomography (CT) imaging to accurately distinguish thyroid eye disease (TED) and orbital myositis, two conditions with overlapping clinical presentations.</p><p><strong>Methods: </strong>Retrospective, single-center cohort study spanning 12 years including normal controls, TED, and orbital myositis patients with orbital imaging and examination by an oculoplastic surgeon. A deep learning model employing a Visual Geometry Group-16 network was trained on various binary combinations of TED, orbital myositis, and controls using single slices of coronal orbital CT images.</p><p><strong>Results: </strong>A total of 1628 images from 192 patients (110 TED, 51 orbital myositis, 31 controls) were included. The primary model comparing orbital myositis and TED had accuracy of 98.4% and area under the receiver operating characteristic curve (AUC) of 0.999. In detecting orbital myositis, it had a sensitivity, specificity, and F1 score of 0.964, 0.994, and 0.984, respectively.</p><p><strong>Conclusions: </strong>Deep learning models can differentiate TED and orbital myositis based on a single, coronal orbital CT image with high accuracy. Their ability to distinguish these conditions based not only on extraocular muscle enlargement but also other salient features suggests potential applications in diagnostics and treatment beyond these conditions.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-9"},"PeriodicalIF":0.9,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Orbital cysticercosis masquerading as trochleodynia.","authors":"Sukhdeep Bains, Yogesh Preet Singh","doi":"10.1080/01676830.2025.2512550","DOIUrl":"https://doi.org/10.1080/01676830.2025.2512550","url":null,"abstract":"<p><p>Trochleodynia is described as a headache caused by peritrochlear inflammation. It presents with tenderness in the trochlear area with exacerbation of vertical eye movements. It is principally idiopathic, but sometimes it is seen in association with other causes like sinusitis or rarely with immune mediated diseases.Cysticercosis is a tissue infection caused by the larval form of the parasite, Taenia solium. The parasite can infect the brain, muscle, eye and other tissues. The presenting features vary according to the site of lodgement of the larva. The extraocular muscles of the eye are the most common site of orbital form of cysticercosis.We report a case in which the lodgement of the cysticercus in the orbit, adjacent to the trochlea caused clinical features suggestive of trochleodynia. Neuroimaging was instrumental in arriving at the true diagnosis of cysticercosis.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-4"},"PeriodicalIF":0.9,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aline Ramos da Silva, Antonio Augusto Cruz, Fernando Chahud, Persio Roxo-Junior
{"title":"Bilateral sino-nasal-orbital fungal necrosis associated with hemophagocytic lymphohistiocytosis.","authors":"Aline Ramos da Silva, Antonio Augusto Cruz, Fernando Chahud, Persio Roxo-Junior","doi":"10.1080/01676830.2025.2509238","DOIUrl":"https://doi.org/10.1080/01676830.2025.2509238","url":null,"abstract":"<p><p>Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory condition caused by hyperactive T cells and macrophages, which release pro-inflammatory cytokines. The diagnosis is based on eight criteria: fever, bi- or tri-lineage cytopenias, splenomegaly, hyperferritinemia, hypofibrinogenemia or hypertriglyceridemia, elevated soluble CD25 levels, low or absent NK cell cytotoxicity, and hemophagocytosis. We report a 1-month-old male infant who was being treated in the pediatric intensive care unit for neonatal infection when he developed six of the eight criteria for HLH, along with bilateral upper eyelid edema that progressed to bilateral sino-nasal-orbital necrosis. MRI revealed a large area of contrast loss involving the nose and both orbits, consistent with fungal necrosis. Biopsy and culture identified <i>Aspergillus fumigatus</i>. Despite antifungal and immunosuppressive treatment, the infant died one week later. We emphasize the need to consider opportunistic fungal infections in HLH patients, particularly when there is rapid and severe clinical deterioration.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-4"},"PeriodicalIF":0.9,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tomographic ultrasound imaging of the anophthalmic socket for future 3D printing of ocular prostheses.","authors":"Linn Engqvist, Ulf Dahlstrand, Olof Neumann, Dyonne Hartong, Jelmer Remmers, Magdalena Naumovska, Rafi Sheikh, Aboma Merdasa, Malin Malmsjö","doi":"10.1080/01676830.2024.2432419","DOIUrl":"10.1080/01676830.2024.2432419","url":null,"abstract":"<p><strong>Purpose: </strong>There is a need for a simple, non-invasive, and easily accessible 3D imaging technique for the anophthalmic socket to create imaging data for future 3D printing of prostheses. This study aimed to investigate the feasibility of using a novel handheld tomographic ultrasound for 3D mapping of the anophthalmic socket.</p><p><strong>Methods: </strong>Ten anophthalmic sockets were scanned using a tomographic ultrasound system and the results were compared to CT scanned impression molds from the same sockets.</p><p><strong>Results: </strong>The tomographic ultrasound provided detailed 3D maps of the anophthalmic sockets. The mean difference between the ultrasound-mapped socket and the CT-scanned imprints was within clinically acceptable limits for most patients. Specifically, the minimum separation distance was less than 3 mm in most cases. In three patients, larger deviations were noted as a result of uneven socket surfaces, indicating the need for further refinement in these cases.</p><p><strong>Conclusions: </strong>Tomographic ultrasound shows promise for 3D imaging of the posterior surface of the anophthalmic socket and may, in the future, support 3D printing of prostheses. However, further refinement is needed to make the technique clinically applicable.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"281-288"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}