Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery最新文献_第4页

Corneal perforation secondary to medial canthal fistula in cocaine-induced midline destructive lesions.

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Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-03-13 DOI: 10.1080/01676830.2025.2477637

Simerdip Kaur, Meydan Ben Ishai, Saul Rajak, Huw Oliphant, Mayank Nanavaty

引用次数: 0

Artificial intelligence based semi-automatic segmentation for orbital tumor preoperative modeling.

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Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-02-28 DOI: 10.1080/01676830.2025.2470359

Margaret B Mitchell, Ryan Bartholomew, Angela Zhu, Benjamin Bleier, Barak Ringel

{"title":"Artificial intelligence based semi-automatic segmentation for orbital tumor preoperative modeling.","authors":"Margaret B Mitchell, Ryan Bartholomew, Angela Zhu, Benjamin Bleier, Barak Ringel","doi":"10.1080/01676830.2025.2470359","DOIUrl":"https://doi.org/10.1080/01676830.2025.2470359","url":null,"abstract":"Purpose: With the increasing utilization of endoscopic approaches for primary benign orbital tumor (PBOT) surgery, otolaryngologists and ophthalmologists are challenged with determining candidacy for endoscopic resection based on preoperative imaging. Our objective was to develop a semi-automatic modality for three-dimensional reconstruction of primary benign orbital tumors to shed light on their resectability.Methods: Patients with tumors from each ORBIT (Orbital Resection by Intranasal Technique) class were identified. Patients' preoperative imaging was obtained, and 3D slicer was utilized to segment the tumor with key anatomical structures, creating a three-dimensional model for each patient.Results: A model was generated for all five ORBIT classes. These models demonstrated the key findings differentiating classes such as whether a tumor is intraconal vs. extraconal, anterior or posterior to the intersection of the ophthalmic artery and optic nerve, or extends into the pterygopalatine and/or infratemporal fossa through inferior orbital fissure or through the superior orbital fissure.Conclusion: Our study utilized 3DSlicer to semi-automatically develop three-dimensional reconstructions of each class of benign orbital tumors as designated by ORBIT criteria. These reconstructions may provide additional quantitative and qualitative data regarding these tumors, their resectability, and the potential surgical approaches required.","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-5"},"PeriodicalIF":0.9,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety and feasibility of performing sentinel lymph node biopsy for periorbital malignancies at freestanding outpatient surgical centers.

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Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-02-28 DOI: 10.1080/01676830.2025.2453972

Alexander A Dennis, Delaram Mirzania, Zhenyang Zhao, Scott A McLean, Hakan Demirci, Vinay Aakalu, Christine C Nelson

{"title":"Safety and feasibility of performing sentinel lymph node biopsy for periorbital malignancies at freestanding outpatient surgical centers.","authors":"Alexander A Dennis, Delaram Mirzania, Zhenyang Zhao, Scott A McLean, Hakan Demirci, Vinay Aakalu, Christine C Nelson","doi":"10.1080/01676830.2025.2453972","DOIUrl":"https://doi.org/10.1080/01676830.2025.2453972","url":null,"abstract":"Purpose: Sentinel lymph node biopsy (SLNB) is vital for stratifying and treating facial and periorbital malignancies, but data on SLNB performed in freestanding outpatient surgical centers (OSC) is scarce.Methods: A retrospective review was conducted on 79 consecutive SLNB procedures from September 2014 to November 2022 at an academic hospital (46 cases) and OSCs (33 cases) affiliated with our institution. We compared demographics, clinical characteristics, wait time, operative time, estimated blood loss (EBL), and complications.Results: Patients at OSCs were younger (mean age 62 vs. 73, p < 0.001) and had lower perioperative risk (ASA score 2.18 vs. 2.71, p < 0.001) than those in a hospital setting. SLNB procedures at OSCs were shorter (73 vs. 113 minutes, p < 0.001) with significantly less EBL (11.48 mL vs. 45.53 mL, p = 0.03), and no complications.Conclusions: SLNB procedures for eligible patients are safe and effective when performed at freestanding outpatient surgical centers affiliated with our institution.","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-6"},"PeriodicalIF":0.9,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adjunct botulinum toxin for cicatricial pemphigoid.

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Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-02-28 DOI: 10.1080/01676830.2025.2470988

Frank Mei, Liane O Dallalzadeh, Preston Choi, Munevver Duran, Jennifer H Cao, Phillip A Tenzel, Ronald Mancini

{"title":"Adjunct botulinum toxin for cicatricial pemphigoid.","authors":"Frank Mei, Liane O Dallalzadeh, Preston Choi, Munevver Duran, Jennifer H Cao, Phillip A Tenzel, Ronald Mancini","doi":"10.1080/01676830.2025.2470988","DOIUrl":"https://doi.org/10.1080/01676830.2025.2470988","url":null,"abstract":"Cicatricial changes secondary to conjunctivitis associated with pemphigoid can include subconjunctival fibrosis, forniceal shortening, symblepharon with resultant entropion and trichiasis. This can ultimately lead to limbal stem cell deficiency and irreversible corneal keratopathy. Herein, we present a case series of three patients at a single academic institution between 2022 and 2024 that underwent botulinum toxin-A injection for lower eyelid cicatricial entropion as a temporizing treatment due to active cicatrizing conjunctivitis. All patients reported subjective improvement in ocular irritation following injection. All patients demonstrated improvement in their eyelid margin position with decreased orbicularis override and improved anterior trajectory of lashes. No patient experienced exacerbation of their pemphigoid and all patients opted for serial injections (mean of 4.3 treatments). This series demonstrates that botulinum toxin-A is an effective tool in the limited armamentum of treatment options for patients with cicatrizing entropion during phases of active cicatrizing conjunctivitis when more definitive conjunctival incisional surgeries are contraindicated.","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-5"},"PeriodicalIF":0.9,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case presentation of a pressurized diesel injury to the orbit, face, and neck.

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Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-02-28 DOI: 10.1080/01676830.2025.2465487

Amee D Azad, Lisa Y Lin, Carolina Chiou, Douglas Dembinski, Christopher D Dwyer, Dane Slentz, Natalie Wolkow

引用次数: 0

Selumetinib use as targeted therapy for plexiform neurofibroma: a comprehensive review of the literature.

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Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-02-28 DOI: 10.1080/01676830.2025.2470989

Hammam A Alotaibi, Hunter Kl Yuen, Askar K Alshaibani, Eman A Alibrahim

引用次数: 0

Retrograde circular intubation for the failed passage of a pigtail lacrimal probe in the management of non-specific inflammatory punctum occlusion.

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Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-02-27 DOI: 10.1080/01676830.2025.2469318

Hesham A Ibrahim, Heba Nabil Sabry

{"title":"Retrograde circular intubation for the failed passage of a pigtail lacrimal probe in the management of non-specific inflammatory punctum occlusion.","authors":"Hesham A Ibrahim, Heba Nabil Sabry","doi":"10.1080/01676830.2025.2469318","DOIUrl":"https://doi.org/10.1080/01676830.2025.2469318","url":null,"abstract":"Purpose: to describe the role of Retrograde Circular Intubation (RCI) technique in the management of non-specific inflammatory punctum occlusion (NIPO).Methods: patients with NIPO who failed conservative treatment underwent 3-snip mini rectangular punctoplasty with adjunctive use of circular canalicular intubation. When the use of the pigtail lacrimal probe was not safely possible, circular intubation was accomplished by the RCI technique. A loop of 6/0 polypropylene suture was introduced into the upper lacrimal drainage system in a retrograde manner from the nose by pulling its two ends up from the puncta with 2/0 polypropylene sutures. The latter were placed between the punctum and the nose by a canulated probe or a Ritleng lacrimal probe (https://youtu.be/n31NKdWIUJM).Results: Thirty-two patients (64 eyes) underwent circular intubation as an adjunct to the 3-snip mini rectangular punctoplasty. In 9 eyes (14%) the pigtail lacrimal probe couldn't pass safely across the upper lacrimal drainage system. Circular tube insertion was still possible with the RCI technique. Circular tubes were removed after two months. Over two years of follow-up, 27 patients (84%) maintained a patent punctum.Conclusion: NIPO not responding to conservative measures can be managed surgically under an umbrella of medications. Circular canalicular intubation with its excellent stability and low morbidity is a valuable adjunctive to the 3-snip mini rectangular punctoplasty. When the passage of the pigtail lacrimal probe fails, circular tubes can be inserted with the RCI technique.","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-7"},"PeriodicalIF":0.9,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immunotherapy for orbital squamous cell carcinoma.

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Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-02-27 DOI: 10.1080/01676830.2025.2469305

Khizar Rana, Mark Beecher, Jessica Y Tong, Tejaswi Bommireddy, Katja Ullrich, Richard Hart, Jwu Jin Khong, Geoffrey Wilcsek, Thomas Hardy, Phung Vu, Dinesh Selva

{"title":"Immunotherapy for orbital squamous cell carcinoma.","authors":"Khizar Rana, Mark Beecher, Jessica Y Tong, Tejaswi Bommireddy, Katja Ullrich, Richard Hart, Jwu Jin Khong, Geoffrey Wilcsek, Thomas Hardy, Phung Vu, Dinesh Selva","doi":"10.1080/01676830.2025.2469305","DOIUrl":"https://doi.org/10.1080/01676830.2025.2469305","url":null,"abstract":"Purpose: To evaluate the demographics, clinical features and response of orbital squamous cell carcinoma treated with immunotherapy in an Australian and New Zealand cohort.Methods: This is a multi-institutional, retrospective case series. Data was collected on patient demographics, clinical presentation, imaging findings, treatment course and outcomes. Details of post-immunotherapy surgical interventions were documented along with their histological findings.Results: Ten patients were included. All patients had invasive orbital squamous cell carcinoma. Perineural spread was present in six patients. Seven patients received Cemiplimab, while three patients received Pembrolizumab. No patients experienced side effects requiring cessation of immunotherapy. One patient died during follow up due to an unrelated cause. Eight (80%) patients had measurable radiological response, whereas one (10%) patient had progressive disease. Two patients had orbital exenteration: one due to progressive disease and one due to residual disease on MRI. One patient had orbital mapping biopsies. Two (66%) patients that had tissue analysis following immunotherapy showed complete pathologic response.Conclusion: Our findings support the emerging role of immunotherapy in the management of invasive orbital squamous cell carcinoma.","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-7"},"PeriodicalIF":0.9,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral orbital inflammation in a pediatric patient with eosinophilic granulomatosis with polyangiitis.

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Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-02-24 DOI: 10.1080/01676830.2024.2448813

Mikayla J Baker, Alisha Kamboj, Amanda C Maltry, Raymond G Areaux, Andrew R Harrison, Ali Mokhtarzadeh

{"title":"Bilateral orbital inflammation in a pediatric patient with eosinophilic granulomatosis with polyangiitis.","authors":"Mikayla J Baker, Alisha Kamboj, Amanda C Maltry, Raymond G Areaux, Andrew R Harrison, Ali Mokhtarzadeh","doi":"10.1080/01676830.2024.2448813","DOIUrl":"https://doi.org/10.1080/01676830.2024.2448813","url":null,"abstract":"A 5-year-old female presented to the ophthalmology clinic with one month of left upper eyelid ptosis and three months of intermittent wheezing and coughing. MRI of the brain and orbits revealed infiltrative enhancement involving both orbits, including the retro-maxillary space, maxillary sinus walls, greater wing of the sphenoid, and possibly the left cavernous sinus. She experienced acute respiratory decompensation in the setting of pansinusitis and tree-in-bud nodular pulmonary opacifications. Laboratory workup revealed anemia, thrombocytosis, and elevated inflammatory markers. An orbitotomy with biopsy demonstrated an eosinophil-rich granulomatous infiltrate, consistent with eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss syndrome. The patient was placed on high-dose steroids and mepolizumab. To our knowledge, this patient represents the youngest case of EGPA with orbital involvement. Further, this case illustrates the importance of prompt orbital biopsy to provide a timely, unified diagnosis, enabling specialists to initiate appropriate disease management to reduce morbidity and mortality.","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-4"},"PeriodicalIF":0.9,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intra-operative visualization of the superior ophthalmic vein in carotid-cavernous fistula.

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Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-02-12 DOI: 10.1080/01676830.2025.2460168

Michael Han, Teresa Chen, Lilangi Ediriwickrema

引用次数: 0