Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology最新文献

{"title":"Para-Hisian Accessory Pathway: Mapping Using Open-Window and Ablation From the Aortic Cusp.","authors":"Serkan Çay, Özcan Özeke, Fırat Özcan, Meryem Kara, Serkan Topaloğlu","doi":"10.5543/tkda.2022.08791","DOIUrl":"10.5543/tkda.2022.08791","url":null,"abstract":"A 28-year-old male with palpitations and a Wolff-Parkinson-White electrocardiographic pattern was referred to our division for ablation. The previous 3 ablation attempts from the right atrioventricular annular side performed at different times in the last year were unsuccessful. His conventional 12-lead surface ECG showed highly possible para-Hisian accessory pathway (AP) localization (Figure 1, Panel A). Prior to mapping, a decapolar catheter was advanced into the coronary sinus for intracardiac reference during activation mapping if orthodromic tachycardia developed. During baseline conditions and also after isoproterenol infusion, no sustainable atrioventricular reentrant tachycardia was induced. The AP effective refractory period was 220 milli seconds during programmed atrial stimulation under isoproterenol infusion. Localization and ablation of APs using a 3D electroanatomic mapping (EAM) system and open-window strategy have been previously defined. 1 The open-window strategy using a 3D EAM system (Carto®3, Biosense Webster Inc., Diamond Bar, Calif, USA) was performed during sinus rhythm. A 20-electrode multipolar mapping catheter with 2 mm inter-electrode distance (Pentaray™ Nav, Biosense Webster Inc.) was used for high-density mapping of the right atrium, tricuspid annulus, and right ventricular. For the open-window strategy, the window-of-interest (WOI) was set according to the surface electrocardiography QRS reference including QRS duration and estimated location of atrial and ventricular intracardiac signals obtained from the multielectrode","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9813987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Systolic Dysfunction on Clinical and Diagnostic Parameters in Pediatric Patients with Isolated Left Ventricular Non-compaction.","authors":"Fatma Sevinc Şengul, Pelin Ayyıldız, Sezen Ugan Atik, Sinem Aydin, Alper Güzeltaş, Yakup Ergül","doi":"10.5543/tkda.2023.09648","DOIUrl":"10.5543/tkda.2023.09648","url":null,"abstract":"<p><strong>Objective: </strong>Left ventricular non-compaction is a rare cardiomyopathy following an early arrest in endomyocardial morphogenesis. This study aimed to present the clinical and electrocardiographic characteristics, diagnostic features, treatment strategies, effects of systolic dysfunction on clinical and diagnostic parameters, and follow-up of pediatric patients diagnosed with left ventricular non-compaction.</p><p><strong>Methods: </strong>We retrospectively reviewed children with isolated left ventricular non-compaction at Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital from January 2010 to June 2020.</p><p><strong>Results: </strong>Fifty-five children were diagnosed with left ventricular non-compaction. Thirty-two patients (58.2%) were male, and the median age of presentation was 8.5 years (1 month-17.9 years). The median follow-up of the study was 19 months (1-121 months). Fourteen (25.5%) presented with systolic dysfunction (ejection fraction < 45%), and 2 presented with resuscitated/aborted cardiac arrest. Electrocardiographic abnormalities were present in 78.2%. Fragmented QRS was observed in 6 patients, and QTc duration was 450 milliseconds and above in 17 patients (30.9%). Electrocardiographic abnormalities, low QRS voltage, fragmented QRS, and thrombus were common in patients with ejection fraction < 45% group. Atrial and ventricular arrhythmias (including ventricular fibrillation-VF) were found with similar frequency in both ejection fraction < 45% and ≥45% groups. One patient with a complete atrioventricular block and 1 with long QT syndrome and severe bradycardia underwent permanent pacemaker implantation. Five (9.1%) patients died.</p><p><strong>Conclusions: </strong>Left ventricular non-compaction has heterogeneous clinical findings in childhood. It is essential to follow-up with the patients closely for the development of ventricular dysfunction or arrhythmias due to the progressive course of the disease. Further studies are needed since life-threatening ventricular arrhythmias can be seen, even in patients with preserved ejection fraction.</p>","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9813988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Plaque Components on Fractional Flow Reserve-Derived Computed Tomography in Severe Coronary Stenosis.","authors":"Toshimitsu Tsugu, Kaoru Tanaka, Yuji Nagatomo, Michel De Maeseneer, Johan De Mey","doi":"10.5543/tkda.2022.57522","DOIUrl":"10.5543/tkda.2022.57522","url":null,"abstract":"<p><p>Fractional flow reserve derived from computed tomography decreases across severe coronary stenosis. The diagnostic accuracy of fractional flow reserve-derived computed tomography is high for severe coronary stenosis. In this report, we present a case of no significant fractional flow reserve-derived computed tomography changes even in severe coronary stenosis. A 75-year-old man showed severe stenosis (85% diameter stenosis) in the distal segment of the right coronary artery on both computed tomography angiography and invasive coronary angiography. However, fractional flow reserve-derived from computed tomography showed no significant changes from the proximal (0.97) to the distal (0.95) segments despite the presence of severe stenotic lesion. This patient had different features including the presence of a large acute marginal branch and significantly lower plaque components in the stenotic lesion compared with another patient who had coronary stenosis in the same segment. A large bifurcation branch and/or proportion of plaque components can affect fractional flow reserve-derived from computed tomography hemodynamics.</p>","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9823519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Observational Study of the Isolated Ostial Diagonal Stenosis in Patients with Chronic Coronary Syndrome.","authors":"Akın Torun, Burak Acar, Göksel Kahraman, Ertan Ural, Teoman Kılıç, Umut Çelikyurt, Aysen Ağır","doi":"10.5543/tkda.2023.74422","DOIUrl":"10.5543/tkda.2023.74422","url":null,"abstract":"<p><strong>Objective: </strong>Isolated ostial diagonal stenoses are very rare lesions in which percutaneous intervention could cause significant vessel compromise, and the long-term results have been reported in a few studies. This study sought the characteristics and long-term follow-up of the patients with isolated osteal diagonal stenosis regarding percutaneous coronary intervention and presence of angina.</p><p><strong>Methods: </strong>The study was an observational retrospective study conducted between January 2014 and December 2020. A total of 9769 patients who underwent coronary angiography were analyzed, and 87 patients had isolated diagonal stenosis. The patients were evaluated according to treatment modality and angina severity in long-term pattern.</p><p><strong>Results: </strong>Median follow-up time was 36 months. A total of 54 (83.1%) patients were followed up with only medical treatment, and 11 (16.9%) patients underwent revascularization in addition to medical treatment. The degree of stenosis of the diagonal artery was significantly higher in the percutaneous coronary intervention group than medical group (P = 0.002) and the patients with wider reference diameter of diagonal artery complaint of more angina (P = 0.007). Class I angina was significantly higher in percutaneous coronary intervention group than medical and the patients with no angina were significantly higher in medical group than percutaneous coronary intervention group.</p><p><strong>Conclusion: </strong>Percutaneous coronary intervention was mainly performed for diagonal arteries with a higher degree of stenosis; however, the patients who underwent percutaneous coronary intervention had angina more than 50% rates. Furthermore, the patients with ongoing angina had a larger diameter of the diagonal artery regardless of the type of treatment.</p>","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9823525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Vitamin D on Myocardial Function Demonstrated by Speckle-Tracking Echocardiography in Children with Beta Thalassemia.","authors":"Ayça Koca Yozgat, Emine Azak, Dilek Kaçar, Melek Işık, Özlem Arman Bilir, Zeliha Güzelküçük, İbrahim İlker Çetin, Namık Yaşar Özbek, Neşe Yaralı","doi":"10.5543/tkda.2023.85265","DOIUrl":"10.5543/tkda.2023.85265","url":null,"abstract":"<p><strong>Objective: </strong>Beta thalassemia major is an inherited hemoglobin disorder resulting in chronic hemolytic anemia. Cardiac involvement is the main cause of death in patients. Speckle-tracking echocardiography is a feasible method for the evaluation of cardiac function via an assessment of the longitudinal deformation of the myocardium through the cardiac cycle. The aim of our study is to evaluate the association between vitamin D deficiency and deformation of the left ventricular myocardium measured by speckle-tracking echocardiography in children with thalassemia major.</p><p><strong>Methods: </strong>In this prospective study, 33 thalassemic patients with vitamin D deficiency were enrolled. Cardiac magnetic resonance T2* value, conventional echocardiography, and speckle tracking, and also left ventricular longitudinal and circumferential strain values were measured. Myocardial functions of the patients with vitamin D deficiency or insufficiency were evaluated by speckle-tracking echocardiography before and after vitamin D replacement.</p><p><strong>Results: </strong>The mean age of the patients was 15.4 ± 3.09 years. Vitamin D level was deficient in 30 (90%) and insufficient in 3 (10%) of them. Speckle-tracking analysis showed a significantly decreased absolute value of the left ventricular global longitudinal strain before vitamin D replacement. A significant improvement in the global longitudinal strain was detected after vitamin D replacement (P < 0.05). A statistically significant increase was observed in parameters showing left ventricular systolic and diastolic functions after vitamin D replacement.</p><p><strong>Conclusion: </strong>Vitamin D deficiency is frequently observed and causes decreased contractility in thalassemic patients. In our study, we observed that our patients' cardiac functions had improved after vitamin D replacement therapy.</p>","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9823521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Focusing on Cardio-Hepatic Syndrome in Heart Failure and Cardiovascular Interventions: Time to Update the Prognostic Risk Scores?","authors":"Oğuz Karaca","doi":"10.5543/tkda.2023.25425","DOIUrl":"10.5543/tkda.2023.25425","url":null,"abstract":"H eart failure (HF) is a multifactorial, heterogeneous disease characterized by congestion and/or reduced cardiac output, leading to unmet metabolic demands of vital organs. Regardless of the etiology or phenotypic features (ischemic vs. non-ischemic, reduced or preserved ejection fraction, severe valvular stenosis or regurgitation), the “inevitable consequence” of the HF syndrome is the progressive end-organ dysfunction. Failure of one or more organ systems (heart itself, lungs, kidneys, liver, intestine, brain, skeletal muscle) has been the main determinant of survival in HF. 1,2 Integration of new pharmacologic agents (saqubitril/valsartan, sodium-glucose cotransporter-2 (SGLT-2) inhibitors) into guideline-directed medical therapy and advancements in interventional and surgical procedures (complex coronary interventions, transcatheter aortic valve implantation (TAVI), Mitra-clip, left ventricular assist devices) have led to a significant improvement in HF mortality in selected patients. 3-7 However, HF still remains a global health problem associated with reduced survival, frequent hospitalizations, and impaired quality of life.","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10199587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to Manage Implantable Cardiac Defibrillator Protection in an Implantable Cardiac Defibrillator-Dependent Patient Undergoing Palliative Radiotherapy?","authors":"Cihan Öztürk, Efe Yılmaz, Gökay Taylan, Murat Gök, Kenan Yalta","doi":"10.5543/tkda.2022.45062","DOIUrl":"10.5543/tkda.2022.45062","url":null,"abstract":"A 61-year-old female patient underwent left breast segmental mastectomy for invasive ductal carcinoma in 2011. Thereafter, trastuzumab therapy was initiated as an adjuvant chemotherapy. However, trastuzumab-related cardiotoxicity developed leading to a left ventricular ejection fraction (LVEF) value of 25% in the patient. Notably, LVEF did not improve with optimal medical treatment on follow-up. Therefore, decision-making for an implantable cardiac defibrillator (ICD) therapy (for primary prevention) was implemented. Implantable cardiac defibrillator was implanted in the right pectoral region due to left mastectomy and lymph node excision. On follow-up, positron emission computed tomography revealed metastatic lesions involving the anterior upper lobe of the right lung and right infraclavicular lymph nodes. The patient was referred to our clinics due to the fact that she had an ICD generator in the vicinity of the metastatic sites (Figure 1A). This might substantially reduce the effectiveness of planned radiotherapy on this region. Moreover, radiotherapy with a cumulative dose of >5 Gy might potentially hamper the ICD generator. Notably, the calculated dose was seemingly over this threshold according to the American Association of Physicists in Medicine Task Group 203. Based on the abovementioned challenges, temporary removal of the ICD generator, leaving the leads in place, and reimplantation of the generator in the same region following radiotherapy were considered. However, even though the patient was not dependent on cardiac pacing by the device, the patient might be","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9813991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Cardiac CT and Circulating Biomarkers in Coronary Artery Disease: Recent Advances for Expanding Cardiac Imaging Access.","authors":"İbrahim Altun","doi":"10.5543/tkda.2023.00557","DOIUrl":"https://doi.org/10.5543/tkda.2023.00557","url":null,"abstract":"","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10049700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Curcumin on Mechanical Functions and Cardiac Contractility in Isolated Rat Hearts.","authors":"Özden Kutlay,&nbsp;Bilgin Kaygısız,&nbsp;Arzu Keskin Aktan","doi":"10.5543/tkda.2022.69765","DOIUrl":"https://doi.org/10.5543/tkda.2022.69765","url":null,"abstract":"<p><strong>Objective: </strong>Curcumin is a bioactive compound that has well-known pharmacological activities. Numerous studies have shown that curcumin provides potential cardiovascular benefits through a variety of mechanisms.The present study aims to discuss different concentrations of curcumin's impact on mechanical functions and cardiac contractility in isolated perfused rat hearts.</p><p><strong>Methods: </strong>The hearts were isolated under sodium thiopental (50 mg/kg) anesthesia and perfused with a modified Krebs-Henseleit solution (mK-Hs). After stabilization, curcumin was applied in concentrations of 0.1, 1, and 10 µM. In isolated rat hearts, indexes of + dP / dt max, LVDP, MAP, and LVEDP were evaluated for cardiac contractility and ventricular function.</p><p><strong>Results: </strong>All curcumin concentrations reduced +dP/dtmax and LVDP. Ten µM curcumin also significantly decreased heart rate. Curcumin (1 and 10 µM) increased LVEDP and reduced MAP amplitude with a concomitant increase in MAP duration. Curcumin at all concentrations did not affect dMAPdtmax and dMAPdtmin.</p><p><strong>Conclusion: </strong>Our results might suggest that curcumin at higher concentrations (≥ 1 µM) increases LVEDP with a negative chronotropic effect and decreases MAP amplitude with an increase in MAP duration. There is sufficient evidence from this study that Curcumin possesses an adverse inotropic action. Different disease models should support the pathophysiological role of Curcumin on cardiac contraction.</p>","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10049699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Comments on Cardiology].","authors":"Ertan Ural","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10032098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}