Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology最新文献

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Cardiac Tamponade Induced by Malignancy-Associated Chylopericardium. 恶性肿瘤相关Chylo心包引起的心脏坦帕。
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Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology Pub Date : 2023-09-01 DOI: 10.5543/tkda.2022.65645
Nazmiye Serap Biçer, Rıdvan Yurt, Cihan Uysal, Nihat Kalay, Oktay Bozkurt, İsmail Koçyiğit
{"title":"Cardiac Tamponade Induced by Malignancy-Associated Chylopericardium.","authors":"Nazmiye Serap Biçer, Rıdvan Yurt, Cihan Uysal, Nihat Kalay, Oktay Bozkurt, İsmail Koçyiğit","doi":"10.5543/tkda.2022.65645","DOIUrl":"10.5543/tkda.2022.65645","url":null,"abstract":"","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10523451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Anesthesia Type Applied in Transcatheter Aortic Valve Implantation. 麻醉类型在经导管主动脉瓣植入术中的应用效果。
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Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology Pub Date : 2023-09-01 DOI: 10.5543/tkda.2023.38920
Şahin Yılmaz, Gönül Zeren, İlhan İlker Avcı, Mustafa Azmi Sungur, Fatma Can, Mehmet Fatih Yılmaz, Barış Şimşek, Ozan Tezen, Can Yücel Karabay
{"title":"The Effect of Anesthesia Type Applied in Transcatheter Aortic Valve Implantation.","authors":"Şahin Yılmaz,&nbsp;Gönül Zeren,&nbsp;İlhan İlker Avcı,&nbsp;Mustafa Azmi Sungur,&nbsp;Fatma Can,&nbsp;Mehmet Fatih Yılmaz,&nbsp;Barış Şimşek,&nbsp;Ozan Tezen,&nbsp;Can Yücel Karabay","doi":"10.5543/tkda.2023.38920","DOIUrl":"10.5543/tkda.2023.38920","url":null,"abstract":"<p><strong>Objective: </strong>Different results have been obtained in studies on the effect of anesthesia type applied during transcatheter aortic valve implantation on in-hospital outcomes. In this study, we aimed to investigate the association of the type of anesthesia with the lenght of stay in the intensive care unit and the need for inotropes in patients undergoing transcatheter aortic valve implantation.</p><p><strong>Methods: </strong>A total of 140 patients who underwent transcatheter aortic valve implantation between January 2016 and January 2022 were retrospectively analyzed. The patients were divided into 2 groups as deep sedation and general anesthesia according to the type of anesthesia.</p><p><strong>Results: </strong>The mean age of all patients was 78.5 ± 8.6 years, and 69 of the patients (49.3%) were female. Length of stay in intensive care unit, midazolam dosage, use of inotropic agents, and procedural hypotension were significantly lower in the deep sedation group than in the general anesthesia group [(1[1-2] vs. 1[1-2.5] days, P = 0.03), (2.1 ± 0.4 mg/kg vs. 2.3 ± 05, P = 0.02), (39 (37.9%) vs. 22 (59.5%), P = 0.02), (41 (39.8%) vs. 25 (67.6%), P = 0.004)]. General anesthesia was associated with increased use of inotropic agents during transcatheter aortic valve implantation compared to deep sedation (odds ratio = 2.93 95% CI = 1.18-7.30, P = 0.02).</p><p><strong>Conclusion: </strong>The use of inotropes is less in transcatheter aortic valve implantation procedures performed under deep sedation and length of stay in intensive care unit is shorter.</p>","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10541264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Myocardial Infarction Caused by Spasm of the Right and Left Coronary Ostia and Discontinuation of Hyperthyroidism Treatment. 一例因左、右冠状动脉狭窄引起的心肌梗死及甲状腺功能亢进症治疗中止。
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Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology Pub Date : 2023-09-01 DOI: 10.5543/tkda.2023.39679
Eri Morita, Yusuke Oba, Hiroshi Funayama, Hisaya Kobayashi, Takahiro Watanabe, Kazuomi Kario
{"title":"A Case of Myocardial Infarction Caused by Spasm of the Right and Left Coronary Ostia and Discontinuation of Hyperthyroidism Treatment.","authors":"Eri Morita,&nbsp;Yusuke Oba,&nbsp;Hiroshi Funayama,&nbsp;Hisaya Kobayashi,&nbsp;Takahiro Watanabe,&nbsp;Kazuomi Kario","doi":"10.5543/tkda.2023.39679","DOIUrl":"10.5543/tkda.2023.39679","url":null,"abstract":"","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10541263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive Value of the SCORE, SCORE2, and Pooled Cohort Risk Equation Systems in Patients with Hypertension. SCORE、SCORE2和合并队列风险方程系统对高血压患者的预测价值。
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Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology Pub Date : 2023-09-01 DOI: 10.5543/tkda.2023.74249
Muammer Karakayalı, Hamdi Püşüroğlu, Mehmet Altunova, Emre Yılmaz, Ayşenur Güllü
{"title":"Predictive Value of the SCORE, SCORE2, and Pooled Cohort Risk Equation Systems in Patients with Hypertension.","authors":"Muammer Karakayalı,&nbsp;Hamdi Püşüroğlu,&nbsp;Mehmet Altunova,&nbsp;Emre Yılmaz,&nbsp;Ayşenur Güllü","doi":"10.5543/tkda.2023.74249","DOIUrl":"10.5543/tkda.2023.74249","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study is to assess and compare the accuracy of old and new versions of the European Society of Cardiology Systematic Coronary Risk Evaluation (SCORE and SCORE2) American Heart Association/American College of Cardiology Pooled Cohort Risk Assessment Evaluation (PCE) in predicting long-term cardiovascular events in patients with hypertension.</p><p><strong>Methods: </strong>This retrospective study consisted of 788 patients diagnosed with hypertension between 2009 and 2018. The absolute risk for 10-year cardiovascular events was calculated with SCORE, SCORE2, SCORE-OP, and PCE systems based on patients' data obtained on the date of hypertension diagnosis. The study group was followed for the occurrence of major adverse cardiac and cerebrovascular events. The differences between observed and predicted risk calculated using SCORE, SCORE2, and PCE systems and their prognostic value were assessed.</p><p><strong>Results: </strong>The mean age of the 788 patients included in the study, of whom 426 (54.1%) were female, was 54 ± 9 years. During a mean follow-up of 6 years, 173 (22.0%) patients experienced a major adverse cardiac and cerebrovascular event. In predicting the occurrence of major adverse cardiac and cerebrovascular events in hypertension patients over the long-term, PCE had a predictive power comparable and slightly superior to 'SCORE2-SCORE-OP (AUC 0.732 vs. 0.724, respectively)' whereas SCORE (AUC 0.689) was inferior to 'SCORE2-SCORE-OP.'</p><p><strong>Conclusion: </strong>In this study, the Pooled Cohort Risk Assessment Equation risk-scoring system was superior to the old and new versions of Systematic Coronary Risk Evaluation risk system in predicting the cardiovascular and cerebrovascular events that developed in patients with hypertension.</p>","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10225852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Variation of Computed Tomography-Derived Fractional Flow Reserve Related to Different Vessel Morphology. 与不同血管形态相关的计算机断层扫描衍生的分数流量储备的变化。
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Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology Pub Date : 2023-09-01 DOI: 10.5543/tkda.2023.60930
Toshimitsu Tsugu, Kaoru Tanaka, Yuji Nagatomo, Michel De Maeseneer, Johan De Mey
{"title":"Variation of Computed Tomography-Derived Fractional Flow Reserve Related to Different Vessel Morphology.","authors":"Toshimitsu Tsugu,&nbsp;Kaoru Tanaka,&nbsp;Yuji Nagatomo,&nbsp;Michel De Maeseneer,&nbsp;Johan De Mey","doi":"10.5543/tkda.2023.60930","DOIUrl":"10.5543/tkda.2023.60930","url":null,"abstract":"<p><p>A total of 1492 outpatients with suspected coronary artery disease and who underwent computed tomography-derived fractional flow reserve analysis were examined. To investigate the effects of vessel morphology such as lumen diameter or volume on computed tomography-derived fractional flow reserve, nearly the same or subthreshold values affecting computed tomography-derived fractional flow reserve hemodynamics vessels were compared. Case 1 and 2 present almost the same vessel length (case 1 vs. case 2; 135.0 mm vs. 133.6 mm), low-attenuation plaque volume (0 mm3 vs. 0 mm3), intermediate attenuation plaque volume (12.5 mm3 vs. 35.5 mm3), and calcified plaque volume (4.7 mm3 vs. 0 mm3) in the right coronary artery. However, lumen volume (877.8 mm3 vs. 2443.7 mm3) and distal computed tomography-derived fractional flow reserve (0.79 vs. 0.96) were markedly different between the 2 patients. Computed tomography-derived fractional flow reserve depends not only on vessel length or plaque characteristics but also on lumen volume or vessel morphology.</p>","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10168868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aortic Elasticity Evaluation: Ongoing Assertion of M-Mode Measurements. 主动脉弹性评估:M型测量的持续断言。
IF 0.8
Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology Pub Date : 2023-09-01 DOI: 10.5543/tkda.2023.24850
Gamze Babur Güler
{"title":"Aortic Elasticity Evaluation: Ongoing Assertion of M-Mode Measurements.","authors":"Gamze Babur Güler","doi":"10.5543/tkda.2023.24850","DOIUrl":"10.5543/tkda.2023.24850","url":null,"abstract":"A therosclerosis, a chronic inflammatory disease, is a leading cause of cardiovascular diseases (CVDs) and requires early detection for effective prevention. 1 Arterial stiffness, characterized by the imbalance of elastin and collagen content in the vessel wall, is an early indicator of atherosclerosis. 2 While arterial stiffness is a useful measure for the prediction of stiffness level of all arteries, the concept of aortic stiffness is frequently used in the clinical assessment of it. In clinical practice, it is an important issue to understand the relationship between aortic stiffness and cardiovascular risk factors. Possible mechanisms linking aortic stiffness and atherosclerosis include common risk factors, mechanical stress on arterial walls, altestress, modynamics, vascular remodeling, and impaired endothelial repair mechanisms. 2 Hypertension, diabetes, dyslipidemia and smoking, which are risk factors for aortic stiffness and atherosclerosis, induce both conditions and lead to endothelial dysfunction, oxidative stress and chronic inflammation. As aortic stiffness increases, it exerts mechanical pressure on the endothelium, impairs its function, increases inflammation and causes plaque formation. 3 Altered hemodynamics due to aortic stiffness raises blood pressure and pulse wave velocity, thereby accelerating atherosclerotic processes in smaller vessels. 4 Arterial stiffness also induces vascular remodeling, stimulating smooth muscle cell proliferation, collagen deposition, and structural changes that promotes plaque formation and aortic stiffness. 2,5 Moreover, aortic stiffness affects endothelial progenitor cells by reducing their mobilization and impairing repair capacity. 6 Knowing these mechanisms focus on the importance of considering aortic stiffness as a modifiable","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10231249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Aortic Elasticity Parameters Measured by Transthoracic Echocardiography in a Normotensive Population: A Single-Center Study. 经胸超声心动图对正常人群主动脉弹性参数的评估:一项单中心研究。
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Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology Pub Date : 2023-09-01 DOI: 10.5543/tkda.2023.88717
Betül Cengiz Elçioglu, Alparslan Kılıç, Onur Baydar, Şükrü Taylan Şahin, Hülya Gamze Çelik, Vedat Aytekin, Saide Aytekin
{"title":"Evaluation of Aortic Elasticity Parameters Measured by Transthoracic Echocardiography in a Normotensive Population: A Single-Center Study.","authors":"Betül Cengiz Elçioglu,&nbsp;Alparslan Kılıç,&nbsp;Onur Baydar,&nbsp;Şükrü Taylan Şahin,&nbsp;Hülya Gamze Çelik,&nbsp;Vedat Aytekin,&nbsp;Saide Aytekin","doi":"10.5543/tkda.2023.88717","DOIUrl":"10.5543/tkda.2023.88717","url":null,"abstract":"<p><strong>Objective: </strong>Impaired arterial elastic features is one of the earliest manifestations of atherosclerosis in the vessel wall and is associated with the development of cardiovascular disease and increased mortality and morbidity. In this study, we aimed to investigate the mean values of aortic elasticity parameters in a normotensive population with transthoracic echocardiography and to evaluate these values in different age groups and their relationship with other risk factors.</p><p><strong>Methods: </strong>This retrospective study included 405 subjects who met the inclusion criteria among 2880 individuals screened between 2020 and 2022. The study population was divided into 5 groups according to their age. Aortic elasticity parameters (aortic strain, aortic stiffness index, and aortic distensibility) were calculated from the associated formulas by measurements made from the ascending aorta in the parasternal long axis.</p><p><strong>Results: </strong>In 405 subjects (mean age 42.18 ± 10.39, 54.3% female), the mean aortic strain value was 15.14 ± 3.56%, the mean aortic stiffness index was 3.24 ± 1.05, and the mean aortic distensibility was 7.48 ± 2.36 cm2/dyn1/103. It was observed that aortic strain and distensibility values significantly decreased with increasing age groups, while aortic stiffness significantly increased. All 3 aortic elasticity parameters were strongly correlated to age. In the multivariate linear regression analysis, age was found to be an independent factor for all aortic elasticity parameters.</p><p><strong>Conclusion: </strong>Aortic elasticity parameters can be evaluated with transthoracic echocardiography in daily practice. Comparing these measurements with normal values in similar age groups may help to detect patients with increased cardiovascular risk in the early period, regardless of the other risk factors.</p>","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10523449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Heart Failure with Reduced Ejection Fraction: A Historical and Theoretical Essay on Evaluation of Pharmacological Treatment]. [射血分数降低的心力衰竭:药理学治疗评价的历史和理论论文]。
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Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology Pub Date : 2023-09-01 DOI: 10.5543/tkda.2023.37807
Serdar Aksöyek
{"title":"[Heart Failure with Reduced Ejection Fraction: A Historical and Theoretical Essay on Evaluation of Pharmacological Treatment].","authors":"Serdar Aksöyek","doi":"10.5543/tkda.2023.37807","DOIUrl":"10.5543/tkda.2023.37807","url":null,"abstract":"","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10284091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Vasospasm Presenting with Acute Coronary Syndrome and Leading to Total Occlusion. 一例罕见的血管痉挛伴急性冠状动脉综合征并导致完全闭塞。
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Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology Pub Date : 2023-09-01 DOI: 10.5543/tkda.2023.73858
Tuncay Güzel
{"title":"A Rare Case of Vasospasm Presenting with Acute Coronary Syndrome and Leading to Total Occlusion.","authors":"Tuncay Güzel","doi":"10.5543/tkda.2023.73858","DOIUrl":"10.5543/tkda.2023.73858","url":null,"abstract":"<p><p>Coronary vasospasm is characterized by transient and reversible vasoconstriction that can cause myocardial ischemia. Patients with acute coronary syndrome may present to the emergency department with various clinical features, including mortal arrhythmias and cardiac arrest. Coronary angiography was performed in a 61-year-old male patient with the diagnosis of acute coronary syndrome due to recurrent angina attacks and dynamic changes in electrocardiography. In the patient whose critical stenosis was not detected in the first imaging, angina attack developed before the procedure was terminated. On control imaging, we detected total occlusion of the left anterior descending artery due to coronary vasospasm. After the administration of intracoronary nitroglycerin, the total occlusion of the left anterior descending artery due to vasospasm completely resolved and the angina attack relieved. It is uncommon for total stenosis to develop immediately after the coronary angiography observes open coronary arteries. However, if total stenosis is detected in patients with recurrent angina attacks without risk factors, intracoronary nitroglycerin can be administered to appropriate patients before intervention.</p>","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10541260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antihypertensive Efficacy Of Nebivolol And Low Dose Spironolactone In Patients With Resistant Hypertension. 奈比洛尔和小剂量螺内酯对顽固性高血压患者的降压疗效。
IF 0.8
Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology Pub Date : 2023-09-01 DOI: 10.5543/tkda.2023.60464
Hamdi Püşüroğlu, Ender Özal, Ahmet Yaşar Çizgici, Yalçın Avcı, Ali Rıza Demir, İsmail Bıyık
{"title":"Antihypertensive Efficacy Of Nebivolol And Low Dose Spironolactone In Patients With Resistant Hypertension.","authors":"Hamdi Püşüroğlu,&nbsp;Ender Özal,&nbsp;Ahmet Yaşar Çizgici,&nbsp;Yalçın Avcı,&nbsp;Ali Rıza Demir,&nbsp;İsmail Bıyık","doi":"10.5543/tkda.2023.60464","DOIUrl":"10.5543/tkda.2023.60464","url":null,"abstract":"<p><strong>Objective: </strong>Resistant hypertension is associated with increased mortality and morbidity. The optimal medical therapy is not fully elucidated in resistant hypertension. There are relatively few studies in the literature on the treatment of resistant hypertension. In this study, we compared the effectiveness of nebivolol 5 mg, a third generation beta-blocker, with spironolactone 25 mg in patients with resistant hypertension.</p><p><strong>Methods: </strong>A total of 81 patients with resistant hypertension were included in the study. The spironolactone group was composed of 38 patients while the nebivolol group was composed of 43 patients. Resistant hypertension was defined as having office blood pressure ≥ 140/90 mmHg while the patients were under 3 or more antihypertensive agents treatment which included diuretic agents. Office and ambulatory blood pressure at basal and after 8 weeks of treatment were recorded.</p><p><strong>Results: </strong>Office systolic blood pressure and diastolic blood pressure in 24-hour ambulatory blood  pressure monitoring were significantly lower when compared to basal values in both nebivolol and spironolactone groups. The decrease in 24-hour mean systolic and diastolic blood pressure in nebivolol group was 14.9 ± 19.8 mmHg and 9.3 ± 12.7 mmHg compared to 19.5 ± 16.4 mmHg and 13.7 ± 10.8 mmHg in the spironolactone group, respectively. The decrease in 24-hour mean systolic and diastolic blood pressure was not significantly different between the nebivolol and spironolactone groups (P = 0.338 and P = 0.153).</p><p><strong>Conclusion: </strong>Nebivolol is an effective treatment option for resistant hypertension and the antihypertensive effect of nebivolol is similar to low-dose spironolactone.</p>","PeriodicalId":46993,"journal":{"name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10541262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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