Variation of Computed Tomography-Derived Fractional Flow Reserve Related to Different Vessel Morphology.

IF 0.9 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology Pub Date : 2023-09-01 DOI:10.5543/tkda.2023.60930

Toshimitsu Tsugu, Kaoru Tanaka, Yuji Nagatomo, Michel De Maeseneer, Johan De Mey

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Abstract

A total of 1492 outpatients with suspected coronary artery disease and who underwent computed tomography-derived fractional ﬂow reserve analysis were examined. To investigate the eﬀects of vessel morphology such as lumen diameter or volume on computed tomography-derived fractional ﬂow reserve, nearly the same or subthreshold values aﬀecting computed tomography-derived fractional ﬂow reserve hemodynamics vessels were compared. Case 1 and 2 present almost the same vessel length (case 1 vs. case 2; 135.0 mm vs. 133.6 mm), low-attenuation plaque volume (0 mm3 vs. 0 mm3), intermediate attenuation plaque volume (12.5 mm3 vs. 35.5 mm3), and calciﬁed plaque volume (4.7 mm3 vs. 0 mm3) in the right coronary artery. However, lumen volume (877.8 mm3 vs. 2443.7 mm3) and distal computed tomography-derived fractional ﬂow reserve (0.79 vs. 0.96) were markedly diﬀerent between the 2 patients. Computed tomography-derived fractional ﬂow reserve depends not only on vessel length or plaque characteristics but also on lumen volume or vessel morphology.

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与不同血管形态相关的计算机断层扫描衍生的分数流量储备的变化。

共有1492名疑似冠状动脉疾病的门诊患者接受了计算机断层扫描衍生的流量储备分数分析。为了研究血管形态（如管腔直径或体积）对计算机断层扫描得出的血流储备分数的影响，对影响计算机断层扫描得到的血流储备血流动力学分数血管的几乎相同或低于阈值的值进行了比较。病例1和2在右冠状动脉中呈现几乎相同的血管长度（病例1与病例2；135.0 mm与133.6 mm）、低衰减斑块体积（0 mm3与0 mm3）、中等衰减斑块容量（12.5 mm3与35.5 mm3）和钙化斑块体积（4.7 mm3与零mm3）。然而，两名患者的管腔容积（877.8 mm3 vs.2443.7 mm3）和远端计算机断层扫描得出的流量储备分数（0.79 vs.0.96）明显不同。计算机断层扫描得出的血流储备分数不仅取决于血管长度或斑块特征，还取决于管腔体积或血管形态。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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