Adolescent Health Medicine and Therapeutics最新文献_第4页

Rape Survivors' Sorrow: Major Depressive Symptoms and Sexually Transmitted Infection Among Adolescent Girls, Southwest Ethiopia. 强奸幸存者的悲伤:埃塞俄比亚西南部青春期女孩的严重抑郁症状和性传播感染。

IF 1.8

Adolescent Health Medicine and Therapeutics Pub Date : 2021-10-29 eCollection Date: 2021-01-01 DOI: 10.2147/AHMT.S331843

Eyob Asefa Belay, Beshea Gelana Deressa

{"title":"Rape Survivors' Sorrow: Major Depressive Symptoms and Sexually Transmitted Infection Among Adolescent Girls, Southwest Ethiopia.","authors":"Eyob Asefa Belay, Beshea Gelana Deressa","doi":"10.2147/AHMT.S331843","DOIUrl":"https://doi.org/10.2147/AHMT.S331843","url":null,"abstract":"Purpose: Rape is one of the sexual violence acts against women globally. Adolescent girls are vulnerable to this event and experience more severe and long-standing adverse effects. Thus, this study aimed to examine major depressive symptoms and associated factors and the level of sexually transmitted infection among female adolescents evaluated for rape cases at Jimma Medical Center.Patients and methods: Institutional-based cross-sectional study was conducted among adolescent girls assessed for rape cases in Jimma Medical Center. Data were collected using structured questionnaire and entered into Epi Data version 3.1 then exported to SPSS version 21.0 for analysis. Descriptive statistics and regression analyses were carried out.Results: A total of 174 raped adolescent females took part in the study. Of the total participants, 155 (89.1%) of these individuals had major depressive symptoms (95 CI %, 84.5-93.7%), while 85 (48.9%) of them had an STI (95% CI, 41.1-56.9%). From logistic regression, place of residence (AOR 14.65, 95%, (p=0.002)), attending school currently (AOR 9.01, 95%, p=0.004), raped by hitting (AOR 17.67, 95%, p<0.001) and unwanted pregnancy (AOR 14.68, 95%, p=0.001) were the variables associated with major depression.Conclusion: This study indicates that adolescents were suffering from several encumbrances like major depressive symptoms, sexually transmitted diseases and unwanted pregnancy. It also indicated that place of residence, school attending, and unwanted pregnancy had an association with major depressive symptoms. Therefore, the need for a comprehensive approach while treating this vulnerable group is highly recommended.","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"12 ","pages":"91-98"},"PeriodicalIF":1.8,"publicationDate":"2021-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/95/f9/ahmt-12-91.PMC8568697.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39871209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Reliability and Validity of Ethiopian Amharic Version of the PedsQL^TM 4.0 Generic Core Scales and PedsQL^TM 3.0 Diabetes Module. 埃塞俄比亚阿姆哈拉语版PedsQLTM 4.0通用核心量表和PedsQLTM3.0糖尿病模块的可靠性和有效性。

IF 1.7

Adolescent Health Medicine and Therapeutics Pub Date : 2021-06-22 eCollection Date: 2021-01-01 DOI: 10.2147/AHMT.S312323

Desalegn Girma, Zinie Abita, Alemnew Wale, Semahagn Tilahun

{"title":"Reliability and Validity of Ethiopian Amharic Version of the PedsQLTM 4.0 Generic Core Scales and PedsQLTM 3.0 Diabetes Module.","authors":"Desalegn Girma, Zinie Abita, Alemnew Wale, Semahagn Tilahun","doi":"10.2147/AHMT.S312323","DOIUrl":"10.2147/AHMT.S312323","url":null,"abstract":"Background: The PedsQLTM 4.0 generic core scales (GCS) assess the generic health by integrating with disease-specific PedsQLTM 3.0 diabetes module (DM). The PedsQLTM 3.0 DM measures the health-related quality of life (HrQoL) specific to diabetes. Even though there is no translation to Ethiopian Amharic, the instruments had translated to different languages and validated. The study is aimed to assess the validity and reliability of the Amharic version of the PedsQLTM 4.0 GCS and the PedsQLTM 3.0 DM in children and adolescents with diabetes.Methods: PedsQLTM 4.0 GCS and the PedsQLTM 3.0 DM were administered on 193 children and adolescents with diabetes and their parents. The validity was examined by the exploratory factor analysis, multitrait/multi-item scaling analysis, and multitrait-multimethod and monotrait-multimethod analysis. Cronbach's alpha coefficient checked the reliability.Results: Cronbach's alpha coefficient for the total PedsQLTM 4.0 GCS (α child self-report= 0.96; α parent proxy report= 0.95) and for total PedsQLTM 3.0 DM (α child self-report= 0.96; α parent proxy report=0.93) were acceptable at individual patient-level analysis. The monotrait-multimethod correlations were higher than multitrait-multimethod correlations. In multitrait/multi-item scale analysis, both total PedsQLTM 4.0 GCS and PedsQLTM 3.0 DM had an excellent item convergent and discriminatory validity success rate.Conclusion: The Amharic versions of the PedsQLTM 4.0 GCS and the PedsQLTM 3.0 DM were valid and reliable instruments to measure the HrQoL of children and adolescents with diabetes.","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"12 ","pages":"77-89"},"PeriodicalIF":1.7,"publicationDate":"2021-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5b/29/ahmt-12-77.PMC8236244.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39053130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preliminary Evidence for Anhedonia as a Marker of Sexual Trauma in Female Adolescents. 快感缺乏作为女性青少年性创伤标志的初步证据。

IF 1.8

Adolescent Health Medicine and Therapeutics Pub Date : 2021-06-14 eCollection Date: 2021-01-01 DOI: 10.2147/AHMT.S300150

Ayse Irem Sonmez, Charles P Lewis, Arjun P Athreya, Julia Shekunov, Paul E Croarkin

{"title":"Preliminary Evidence for Anhedonia as a Marker of Sexual Trauma in Female Adolescents.","authors":"Ayse Irem Sonmez, Charles P Lewis, Arjun P Athreya, Julia Shekunov, Paul E Croarkin","doi":"10.2147/AHMT.S300150","DOIUrl":"https://doi.org/10.2147/AHMT.S300150","url":null,"abstract":"Introduction: Major depressive disorder (MDD) is a common condition with heterogeneous presentations that often include predominant anhedonia. Previous studies have revealed that childhood trauma is a potent risk factor for the development of MDD; however, the clinical implications of this finding are not fully understood.Methods: Participants were adolescents (age 13-21 years) with a diagnosis of moderate-to-severe major depressive disorder and healthy controls. We used generalized linear models to assess the relationship between anhedonia severity and trauma severity in a cross-sectional dataset.Results: This cross-sectional analysis of an adolescent sample that underwent clinical evaluations and a trauma assessment, suggested that anhedonia was associated with historical trauma severity. The association between anhedonia and sexual abuse was greater in female participants compared to male participants.Discussion: Our results were partially in line with the reported literature in adult samples. Future studies aiming to characterize the trauma-anhedonia relationship in adolescents should utilize scales designed specifically to measure these constructs in young populations, and scales that assess specific subtypes of anhedonia.","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"12 ","pages":"67-75"},"PeriodicalIF":1.8,"publicationDate":"2021-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e0/29/ahmt-12-67.PMC8213949.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39099097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Natural History and Disease Burden of Neurofibromatosis Type 1 with Plexiform Neurofibromas: A Systematic Literature Review. 1型神经纤维瘤病伴丛状神经纤维瘤的自然病史和疾病负担:系统文献综述。

IF 1.8

Adolescent Health Medicine and Therapeutics Pub Date : 2021-05-19 eCollection Date: 2021-01-01 DOI: 10.2147/AHMT.S303456

Catherine Copley-Merriman, Xiaoqin Yang, Melissa Juniper, Suvina Amin, Hyun Kyoo Yoo, Shuvayu S Sen

{"title":"Natural History and Disease Burden of Neurofibromatosis Type 1 with Plexiform Neurofibromas: A Systematic Literature Review.","authors":"Catherine Copley-Merriman, Xiaoqin Yang, Melissa Juniper, Suvina Amin, Hyun Kyoo Yoo, Shuvayu S Sen","doi":"10.2147/AHMT.S303456","DOIUrl":"https://doi.org/10.2147/AHMT.S303456","url":null,"abstract":"Neurofibromatosis type 1 (NF1) is an incurable genetic condition that frequently includes the development of plexiform neurofibromas (PNs) in patients. A systematic literature review was conducted to identify data on the natural history, disease burden, and treatment patterns among patients diagnosed with NF1 and PN, as well as to identify evidence gaps in these areas. MEDLINE and MEDLINE In-Process, Embase, and Cochrane Library Searches were searched using predefined terms. Potential references underwent two phases of screening by two independent researchers. A total of 39 references focusing on populations of patients with both NF1 and PN were included in this review. The wide range of PN-related complications creates a substantial quality-of-life (QOL) burden for patients, including pain, social functioning, physical function impact, stigma, and emotional distress. The severe burden of NF1 with PN on the QOL of patients demonstrates the high unmet need for an effective treatment option that can reduce tumor burden and improve QOL. The heterogeneity of measurement tools used to evaluate QOL and the gap in data evaluating the health economic burden of PN should be the focus of future research.","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"12 ","pages":"55-66"},"PeriodicalIF":1.8,"publicationDate":"2021-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3a/54/ahmt-12-55.PMC8141405.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39022361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Adolescent Hepatitis C: Prevalence, Impact, and Management Challenges. 青少年丙型肝炎:流行、影响和管理挑战。

IF 1.8

Adolescent Health Medicine and Therapeutics Pub Date : 2021-05-07 eCollection Date: 2021-01-01 DOI: 10.2147/AHMT.S263864

Paula Chaves Mari, Reema Gulati, Philip Fragassi

{"title":"Adolescent Hepatitis C: Prevalence, Impact, and Management Challenges.","authors":"Paula Chaves Mari, Reema Gulati, Philip Fragassi","doi":"10.2147/AHMT.S263864","DOIUrl":"https://doi.org/10.2147/AHMT.S263864","url":null,"abstract":"The prevalence of Hepatitis C virus infection (HCV), a leading cause of chronic liver disease worldwide, is rising in the United States (US) and other high-income countries, especially among youth and young adults. This surge in cases is closely associated with the opioid crisis and intravenous drug use (IVDU). However, its prevalence and impact on the adolescent population have not been thoroughly studied and therefore is poorly understood. The pediatric population tends to have milder liver disease and progression when compared to adults; however, there is a risk of developing liver cirrhosis, in addition to facing decreased quality of life and stigmatization from the disease. The recent approval of direct-acting antiviral (DAA) regimens for all HCV genotypes and age greater than 3 years has revolutionized its management. Therapy has shifted from the prolonged interferon-based regimens, to shorter duration, once daily oral pills that are highly effective, curative and with fewer side effects. Therapy is now indicated for all adolescents with hepatitis C virus infection, regardless of stage of liver disease, recent IVDU, or coinfection with HIV, therefore eliminating a lifetime risk of chronic liver disease, cirrhosis and hepatocarcinoma. Nonetheless, adolescents are rarely tested or treated for hepatitis C infection, and very few adolescents complete therapy. Implementation of point of care (POC) testing of high-risk youth at drug treatment centers or other juvenile facilities may be a good strategy to increase testing, diagnosis and therapy. This review article aims to educate pediatricians and other primary care providers to help decrease the existing knowledge gap on the subject.","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"12 ","pages":"45-53"},"PeriodicalIF":1.8,"publicationDate":"2021-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/87/dd/ahmt-12-45.PMC8112853.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38998511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Virtual Consultations: Young People and Their Parents' Experience. 虚拟咨询:年轻人和他们父母的经验。

IF 1.8

Adolescent Health Medicine and Therapeutics Pub Date : 2021-04-28 eCollection Date: 2021-01-01 DOI: 10.2147/AHMT.S292977

Stephanie Proulx-Cabana, Terry Yvonne Segal, Anna Gregorowski, Dougal Hargreaves, Halina Flannery

{"title":"Virtual Consultations: Young People and Their Parents' Experience.","authors":"Stephanie Proulx-Cabana, Terry Yvonne Segal, Anna Gregorowski, Dougal Hargreaves, Halina Flannery","doi":"10.2147/AHMT.S292977","DOIUrl":"https://doi.org/10.2147/AHMT.S292977","url":null,"abstract":"Purpose: Evaluate the experience of virtual consultations for young people and their families and assess whether young people are being offered a confidential space as part of these virtual encounters.Patients and methods: An anonymous online survey was sent to young people age 10-18 y.o. who had experienced at least one virtual consultation with an adolescent medicine tertiary service in the United Kingdom between March 13th and June 13th 2020 mostly associated with, but not exclusively, management of chronic fatigue syndrome or medically unexplained symptoms. Responses from the survey were analysed by two authors who independently coded the common themes reported by the participants.Results: Fifty young people and their families participated in the survey. Eighty-eight percent reported feeling prepared for virtual appointments, 90% found them helpful, 88% felt that they were private and 86% reported they would find further virtual appointments helpful. Positive impacts reported were no need to travel (38%) and the continuity of care (36%). Many of our participants reported no negative impact (39%) and felt that nothing needed to be improved (56%). The most frequent improvement reported was the provision of a quality video call (34%). Only 36% of young people had the opportunity to speak in confidence to the health care provider without their parents' presence.Conclusion: Virtual appointments are perceived as safe and helpful by the young people and their families. Professionals should offer a confidential remote space for young people to speak without their parents.","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"12 ","pages":"37-43"},"PeriodicalIF":1.8,"publicationDate":"2021-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/36/74/ahmt-12-37.PMC8088977.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38963518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

In the Name of Prevention: Maternal Perspectives on School-Based HPV Vaccination in Rural Southern Chile. 以预防的名义:在智利南部农村以学校为基础的HPV疫苗接种的母亲观点。

IF 1.8

Adolescent Health Medicine and Therapeutics Pub Date : 2021-04-21 eCollection Date: 2021-01-01 DOI: 10.2147/AHMT.S299600

Ryan Arams, Rachel E Weinstock, Emma Satterthwaite Muresianu, Stasha O'Callaghan, Elizabeth Tubridy, Yumarlin Torres Maita, Siobhan M Dolan

{"title":"In the Name of Prevention: Maternal Perspectives on School-Based HPV Vaccination in Rural Southern Chile.","authors":"Ryan Arams, Rachel E Weinstock, Emma Satterthwaite Muresianu, Stasha O'Callaghan, Elizabeth Tubridy, Yumarlin Torres Maita, Siobhan M Dolan","doi":"10.2147/AHMT.S299600","DOIUrl":"https://doi.org/10.2147/AHMT.S299600","url":null,"abstract":"Purpose: Since the introduction of the HPV vaccine in Chile in 2014, there have been few studies exploring community perspectives on the vaccine, specifically of parents of adolescents. This study sought to identify maternal factors and family dynamics that affect HPV vaccination behavior.Participants and methods: Participants were recruited at an OB/GYN clinic in Linares, Chile. Participation was voluntary, and eligibility required 1) having an adolescent daughter between 9 and19 years-old and 2) demonstrating a willingness to discuss HPV-related topics. Thirty semi-structured interviews were conducted to generate qualitative data analyzed using Grounded Theory methodology.Results: Three thematic constructs emerged from the interviews. Mothers' motivations to vaccinate centered on disease prevention and trust in the medical system but were influenced by notions of sexual liberalism and promiscuity. Second, participants desired, but often had trouble finding, adequate information about vaccine safety and turned to the internet. Third, joint decision making in the family about vaccination led to open family discussions about sex and sexuality.Conclusion: Chile's school-based opt-out HPV vaccination program engenders a unique landscape of maternal decision-making, risk-benefit analysis, information-seeking, and at-home discussion. More studies are needed around the variable role of fathers in the decision-making process.","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"12 ","pages":"27-36"},"PeriodicalIF":1.8,"publicationDate":"2021-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ac/61/ahmt-12-27.PMC8071695.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38918776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Sexual Assault Profile in Jimma University Medical Center, Southwest Ethiopia. 埃塞俄比亚西南部吉马大学医学中心的性侵犯档案。

IF 1.8

Adolescent Health Medicine and Therapeutics Pub Date : 2021-03-29 eCollection Date: 2021-01-01 DOI: 10.2147/AHMT.S292110

Yibeltal Siraneh, Abonesh Taye, Fanta Asefa, Abraraw Tesfaye, Yesuf Ahmed

{"title":"Sexual Assault Profile in Jimma University Medical Center, Southwest Ethiopia.","authors":"Yibeltal Siraneh, Abonesh Taye, Fanta Asefa, Abraraw Tesfaye, Yesuf Ahmed","doi":"10.2147/AHMT.S292110","DOIUrl":"https://doi.org/10.2147/AHMT.S292110","url":null,"abstract":"Background: Sexual assault cases are increasingly reported in Ethiopia and worldwide. However, in Ethiopia, sexual assaults' profile was not investigated well, regardless of its social, physical, and psychological impacts on survivors. Hence, this study assessed the survivors' characteristics, circumstances of the victims, and treatment offered with the view of describing the management process, and service responsiveness.Methods: A descriptive study with 3 years retrospective chart review was conducted in Jimma University Medical Center (JUMC). Samples of 187 charts/medical records were selected using a systematic random sampling technique from the medical unit. The selected survivors' records were reviewed using a structured checklist. Data were analyzed using SPSS Version 21.0.Results: Out of the 187 cases of sexual assaults during the study period, 67.4% were rape cases. Among these, 58.8% were below 14 years, and 85.6% knew their assailants. Above 30% of the victims were assaulted during the daytime, and 51.9% developed perennial laceration. Threat and physical force were mostly used to coerce victims during the violence. All of the survivors were not investigated for vaginal/anal swab (for sperm analysis), and 96.8% of the victims were not tested for HIV screening. Only 8% of the victims received emergency contraception.Conclusion and recommendation: Children and adolescents remain the most sexually assaulted group of the population, requiring protection and appropriate medical services to ensure their well-being and reduce their suffering. Appropriate and timely intervention is needed to care for such survivors. The findings have highlighted the need for closer monitoring and better follow-up of the care and support provided in the Medical Center to sexual assault victims.","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"12 ","pages":"17-25"},"PeriodicalIF":1.8,"publicationDate":"2021-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/67/b1/ahmt-12-17.PMC8018553.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25565807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Leptin is Associated with the Tri-Ponderal Mass Index in Children: A Cross-Sectional Study. 瘦素与儿童三脑质量指数相关:一项横断面研究。

IF 1.8

Adolescent Health Medicine and Therapeutics Pub Date : 2021-03-09 eCollection Date: 2021-01-01 DOI: 10.2147/AHMT.S289973

Brianna Empringham, William J Jennings, Raeesha Rajan, Adam J Fleming, Carol Portwine, Donna L Johnston, Shayna M Zelcer, Shahrad Rod Rassekh, Victoria Tran, Sarah Burrow, Lehana Thabane, M Constantine Samaan

{"title":"Leptin is Associated with the Tri-Ponderal Mass Index in Children: A Cross-Sectional Study.","authors":"Brianna Empringham, William J Jennings, Raeesha Rajan, Adam J Fleming, Carol Portwine, Donna L Johnston, Shayna M Zelcer, Shahrad Rod Rassekh, Victoria Tran, Sarah Burrow, Lehana Thabane, M Constantine Samaan","doi":"10.2147/AHMT.S289973","DOIUrl":"https://doi.org/10.2147/AHMT.S289973","url":null,"abstract":"Background: Obesity is characterized by the disproportionate expansion of the fat mass and is most commonly diagnosed using the Body Mass Index (BMI) z-score or percentile in children. However, these measures associate poorly with the fat mass. This is important, as adiposity is a more robust predictor of cardiometabolic risk than BMI-based measures, but there are limited clinical measures of adiposity in children. A new measure, the Tri-ponderal Mass Index (TMI, kg/m3) has recently demonstrated robust prediction of adiposity in children. The aim of this study is to explore the association of leptin, a validated biomarker of the fat mass, with TMI.Methods: One hundred and eight children and adolescents were included in this cross-sectional study. Height and weight were used to calculate TMI. Plasma leptin was measured using ELISA. Multivariable regression analysis was applied to determine the predictors of TMI.Results: The age range of participants included in this study was 8.00-16.90 years (female n=48, 44%). Leptin correlated with BMI percentile (r=0.64, p-value <0.0001) and TMI (r=0.71, p-value <0.0001). The multivariable regression analysis revealed that BMI percentile (Estimated Beta-coefficient 0.002, 95% CI 0.002-0.003, p-value <0.0001) and Leptin (Estimated Beta-coefficient 0.05, 95% CI 0.02-0.07, p-value 0.013) were associated with TMI.Conclusion: Leptin is associated with TMI in healthy children. The TMI is a feasible clinical measure of adiposity that may be used to stratify children and adolescents for further assessments and interventions to manage and attempt to prevent cardiometabolic comorbidities.","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"12 ","pages":"9-15"},"PeriodicalIF":1.8,"publicationDate":"2021-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/29/28/ahmt-12-9.PMC7955735.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25485049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A Comparison of the Process and Content of Sexual Communications Among African American Adolescent Children Living in Parent and Grandparent Headed Families. 非裔美国青少年父母与祖父母家长家庭性交流的过程与内容比较。

IF 1.8

Adolescent Health Medicine and Therapeutics Pub Date : 2021-01-07 eCollection Date: 2021-01-01 DOI: 10.2147/AHMT.S281662

Judith B Cornelius, Florence Okoro, Crystal N Piper

{"title":"A Comparison of the Process and Content of Sexual Communications Among African American Adolescent Children Living in Parent and Grandparent Headed Families.","authors":"Judith B Cornelius, Florence Okoro, Crystal N Piper","doi":"10.2147/AHMT.S281662","DOIUrl":"https://doi.org/10.2147/AHMT.S281662","url":null,"abstract":"Introduction: The process of parental sexual communication has been shown to delay the sexual debut of adolescents; however, few studies have focused on extended family members such as grandparents. The purpose of this study was to compare the process and content of sexual communications among African-American adolescent children living in parent or grandparent headed families.Methods: A secondary analysis of two de-identified datasets from 80 African-American adolescents was conducted.Results: Findings indicated that there were no significant differences in the sexual communication process in relation to facilitators p= 0.38 and barriers p =0.23 with the discussions. There were however significant differences with adolescents' attitudes (p = 0.04) and feelings regarding sexual abstinence (p =0.01), HIV prevention (p= 0.002) and teen pregnancy (p= 0.010).Discussion: Researchers can use the results of this study as a beginning point in examining the sexual communication process in grandparent-headed families.","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"12 ","pages":"1-8"},"PeriodicalIF":1.8,"publicationDate":"2021-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/84/66/ahmt-12-1.PMC7800460.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39153553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0