Adolescent Health Medicine and Therapeutics最新文献

{"title":"Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) in Adolescents: Practical Guidance and Management Challenges.","authors":"Katherine Rowe","doi":"10.2147/AHMT.S317314","DOIUrl":"https://doi.org/10.2147/AHMT.S317314","url":null,"abstract":"<p><p>This paper reviews the current understanding of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and whether any treatment strategies have been effective. ME/CFS is a condition of as yet unknown etiology that commonly follows an infective process. It includes a new onset of fatigue (of more than 3-6 month duration and not relieved by rest), post-exertional malaise, cognitive difficulties and unrefreshing sleep, and frequently orthostatic intolerance, somatic symptoms and pain. Long COVID has renewed interest in the condition and stimulated research with findings suggestive of a multisystem neuroimmune disease. There are no definitively effective treatments. Despite earlier recommendations regarding graded exercise therapy and cognitive behavior therapy, the current recommendations are managing symptoms, with lifestyle management and supportive care. This paper provides an outline of strategies that young people and their families have reported as helpful in managing a chronic illness that impacts their life socially, physically, emotionally, cognitively and educationally. As the illness frequently occurs at a time of rapid developmental changes, reducing these impacts is reported to be as important as managing the physical symptoms. Young people face a mean duration of 5 years illness (range 1-16 years) with a likely residual 20% having significant restrictions after 10 years. Their feedback has suggested that symptom management, self-management strategies, advocacy and educational liaison have been the most helpful. They value professionals who will listen and take them seriously, and after excluding alternative diagnoses, they explain the diagnosis, are supportive and assist in monitoring their progress. Remaining engaged in education was the best predictor of later functioning. This allowed for social connections, as well as potential independence and fulfilling some aspirations. The need to consider the impact of this chronic illness on all aspects of adolescent development, as part of management, is highlighted.</p>","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"14 ","pages":"13-26"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c4/a2/ahmt-14-13.PMC9827635.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10515899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of Sexual and Reproductive Health Rights Among University Students: A Cross-Sectional Study in Southeast Ethiopia.","authors":"Chala Kene,&nbsp;Girma Geta,&nbsp;Neway Ejigu,&nbsp;Fikreab Desta","doi":"10.2147/AHMT.S394883","DOIUrl":"https://doi.org/10.2147/AHMT.S394883","url":null,"abstract":"<p><strong>Background: </strong>In many situations, it can still be challenging to talk about sexual and reproductive health rights, and the little scientific research available indicates that university students have a poor understanding of these issues. Therefore, the aim of this study was to assess the knowledge of sexual and reproductive health rights among university students in southeast Ethiopia.</p><p><strong>Methodology: </strong>From February to March 2022, 483 study participants took part in an institutionally based cross-sectional study. The study participants were chosen using a SRS method. EpiData version 4.6.2.0 was used to enter data, and SPSS version 26.0 was used to analyze it. A bivariate and multivariable binary logistic regression model was used to identify factors associated with SRHR knowledge. The odds ratio and a 95% confidence interval were used to calculate the significance level.</p><p><strong>Results: </strong>The optimal level of knowledge on SRHR was discovered to be 52.1% [95% CI (47.32-55.08)] among university students in southeast Ethiopia. The multivariate binary logistic analysis indicated that being urban in the origin of residency [AOR=1.52, 95% CI (1.02-1.14)], being a health student [AOR= 12.21, 95% CI (7.27-14.88)], attending secondary school in private [AOR=6.12, 95% CI (1.02-1.14)], accessibility of a RH club on campus [AOR=6.12, 95% CI (1.02-1.14)] and participating in RH club [AOR=3.95, 95% CI (3.47-5.90)] to be variables that are strongly related to the optimal level of knowledge.</p><p><strong>Conclusion and recommendation: </strong>Four out of ten students had poor knowledge of SRHR. The variables associated with a high level of knowledge about SRHR were urban residency, health students, attending a private secondary school, the availability of a RH club on campus, and participation in a RH club. Including sexual education in the non-health department's course, establishing RH clubs on campus, and encouraging participation of students in these clubs are recommended.</p>","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"14 ","pages":"1-12"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bd/f2/ahmt-14-1.PMC9829977.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10519509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Associated with the Human Papillomavirus Vaccine Coverage in Gulu District, Uganda.","authors":"Isaac Odongo Ojok,&nbsp;John Baptist Ogwal,&nbsp;Brian Wwesige,&nbsp;Felix Bongomin,&nbsp;Franceska Akello","doi":"10.2147/AHMT.S397734","DOIUrl":"https://doi.org/10.2147/AHMT.S397734","url":null,"abstract":"<p><strong>Background: </strong>Human papillomavirus (HPV) vaccination is an effective public health measure for the prevention of cancer of the cervix. We aimed to assess HPV vaccine coverage and associated factors in Gulu, Uganda.</p><p><strong>Methods: </strong>In October 2021, we conducted a cross-sectional study among girls aged 9 to 13 years residing in Pece-Laroo Division, Gulu City, Uganda. HPV vaccine coverage was defined as receipt of at least a dose of the HPV vaccine.</p><p><strong>Results: </strong>A total of 197 girls, with a mean age of 11±1.4 years, were enrolled. Most participants were of the Acholi tribe (89.3%, n=176), catholic (58.4%, n=115), and in primary 5 level of education (36%, n=71). Overall, 68(35%) participants had received the HPV vaccine. Factors associated with HPV vaccine utilization were, good knowledge of the HPV vaccine (adjusted odds ratio (aOR) =0.233, 95% confidence interval (95CI): 0.037-0.640, p=0.101), methods of HPV prevention (OR=0.320, 95CI: 0.112-0.914, p = 0.033), good knowledge of the importance of HPV vaccination (OR=0.458, 95% CI: 0.334-0.960, p=0.021), knowledge on frequency of HPV vaccination (OR=0.423, 95CI:0.173-0.733, p=0.059), and good mobilization (OR=0.443, 95% CI: 0.023-0.923, p=0.012).</p><p><strong>Conclusion: </strong>In this community-based study, only one third of eligible girls received the HPV vaccine. Public health interventions are recommended exponentially to enhance the utilization of the HPV vaccine in this community.</p>","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"14 ","pages":"87-96"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/72/f9/ahmt-14-87.PMC10083017.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9290223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing Dermatologic Effects of Gender-Affirming Therapy in Transgender Adolescents.","authors":"Christina Huang, Sarah Gold, Rakan Radi, Seth Amos, Howa Yeung","doi":"10.2147/AHMT.S344078","DOIUrl":"10.2147/AHMT.S344078","url":null,"abstract":"<p><p>Transgender adolescents seek gender-affirming medical care to address gender identity and incongruence. Improved understanding of the dermatologic impact of gender-affirming medical care such as pubertal suppression, hormone therapy, and surgeries can enhance patient outcome. Pubertal suppression treats dysphoria associated with development of secondary sex characteristics, including androgen-driven acne. Gender-affirming hormone therapy influences acne and hair development in transgender adolescents. Dermatologists can help manage skin effects associated with chest binding and gender-affirming hormone therapy and surgery. Provision of patient-centered gender-affirming care in dermatologic and multidisciplinary settings is essential to improve skin and overall outcomes of gender-affirming therapy.</p>","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"13 ","pages":"93-106"},"PeriodicalIF":1.7,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/df/3b/ahmt-13-93.PMC9552673.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9474875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual and Reproductive Health Problems and Needs of Street Youths in East Gojjam Zone Administrative Towns, Ethiopia: Exploratory Qualitative Study","authors":"Atsede Alle Ewunetie, Mulunesh Alemayehu, Bekalu Endalew, Hailemariam Abiye, Getnet Gedif, Muluye Molla Simieneh","doi":"10.2147/AHMT.S358140","DOIUrl":"https://doi.org/10.2147/AHMT.S358140","url":null,"abstract":"Background About 600,000 children are estimated to depend on street life in Ethiopia. Estimates conclude that about 65% of street children hardly have any access to sexual and reproductive health (SRH) services. However, sexually transmitted infections including HIV/AIDS among street children have been reported as being very high and some studies showed that it can be higher than that of female sex workers, truck drivers and prisoners. Objective The aim of this study is to explore the sexual and reproductive health problems of street youths and their need in East Gojjam Zone, Ethiopia, 2019. Methods An explanatory qualitative study design was conducted on street youths residing in East Gojjam Zone town administrations from February to March, 2019. Purposively selected street youths and positioned individuals who were residing in East Gojjam Zone town administrates were included in the study. The data were collected through focus group discussion and in-depth interview and analyzed thematically. Result A total of 85 street youths and 8 individuals who were working with street children participated in this study. Most street youths had no clear information towards sexual and reproductive health. The existing reproductive health problems were sexual violence, sexually transmitted infection, unplanned pregnancy, abortion and substance abuse. Most street youths were interested in getting sexual and reproductive health information and other services by concerned bodies similar to the general population. Accessibility of job opportunities was also one of their needs to prevent the existing sexual and reproductive health problems. Conclusion and Recommendation Most street youths were sexually active and attempted unsafe sexual practice which exposed them to sexually transmitted infections, unplanned pregnancies and abortions. So a special reproductive health service is needed to avert these problems.","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"13 1","pages":"55 - 66"},"PeriodicalIF":1.8,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45821988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Telehealth in the Management of Adolescent Eating Disorders: Patient Perspectives and Future Directions Suggested from the COVID-19 Pandemic","authors":"S. Gorrell, Erin E. Reilly, L. Brosof, D. Le Grange","doi":"10.2147/AHMT.S334977","DOIUrl":"https://doi.org/10.2147/AHMT.S334977","url":null,"abstract":"Abstract Efforts to increase accessibility of eating disorder (ED) treatment via telemedicine have been ongoing for the past decades. However, there has been a recent surge in research focused on remote delivery of interventions since the onset of the novel coronavirus pandemic (COVID-19) in 2020, the related lockdowns, and an exponential increase in ED symptoms in youth secondary to the pandemic worldwide. In the current review, we provide a focused summary of existing literature regarding telehealth for the treatment of EDs in adolescents using a frame of past, present, and future work. Specifically, we begin with a brief overview of research in remote delivery for EDs in youth prior to 2020. Then, we detail more recent studies in this domain, with a focus on research conducted during the COVID-19 pandemic. We close by outlining limitations of the existing data and future steps necessary to expand the rigor and impact of this work. Overall, there are considerable limitations associated with research conducted during the pandemic, but an increase in the acceptability of remote delivery methods and interest in hybrid care appears to be feasible, and likely to be lasting. Future work must replicate more recent research in non-pandemic contexts and prioritize evaluation of factors that will aid in matching patients to the most efficient and effective modalities of care moving forward.","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"13 1","pages":"45 - 53"},"PeriodicalIF":1.8,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49335006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum: Perspectives on Adolescent Pregnancy Prevention Strategies in the United States: Looking Back, Looking Forward [Corrigendum].","authors":"","doi":"10.2147/AHMT.S402218","DOIUrl":"https://doi.org/10.2147/AHMT.S402218","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.2147/AHMT.S219949.].</p>","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"13 ","pages":"107-108"},"PeriodicalIF":1.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/de/b2/ahmt-13-107.PMC9805729.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10477076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-Sectional Analysis of Nutritional Status, Knowledge and Uptake of Nutritional Services Among Adolescent Girls in Western India.","authors":"Somen Saha,&nbsp;Apurvakumar Pandya,&nbsp;Yogini Kandre,&nbsp;Devang Raval,&nbsp;Deepak Saxena","doi":"10.2147/AHMT.S336071","DOIUrl":"https://doi.org/10.2147/AHMT.S336071","url":null,"abstract":"<p><strong>Purpose: </strong>Malnutrition status of adolescent girls remains a major public health problem in India. The present study assessed nutritional status, associated factors contributing to malnutrition and their access to health-care services in Dev Bhumi Dwarka district of Gujarat situated in western part of India.</p><p><strong>Materials and methods: </strong>The study was carried out using descriptive cross-sectional design. A total of 1252 adolescent girls from all four blocks of Dev Bhumi Dwarka district were interviewed by field investigators. The data were collected on socio-demographic characteristics, physical activities, diet, and anthropometry. The WHO classification for body mass index (BMI) was used to assess underweight, overweight, and obesity among adolescent girls. Chi-square analyses were performed to identify significant determinants of under-nutrition.</p><p><strong>Results: </strong>Mean age of the study population was 13.82±2.31. Of the total, around 34% of the adolescent girls were out-of-school. The prevalence of underweight (<-2SD) was 19.6%, 8.9% were overweight, and 2.6% were obese. The mean BMI was 19.77±2.42 kg/m², and height was 149.15 (2.23m²). In terms of knowledge, almost 79.6% were unaware of iron-deficiency anaemia, about 70% were not aware of haemoglobin test, and 44% did not know the benefit of using sanitary napkins. In addition, uptake of nutritional and health services was limited. The study found a statistically significant association of age (p = 0.00), the number of family members (p = 0.016), knowledge (p = 0.05), and use of toilet (0.041) with low-BMI.</p><p><strong>Conclusion: </strong>Existing nutritional interventions need to focus on nutrition, health and hygiene education. It also reinforces a need for implementation research to understand barriers in uptake of health and nutrition services.</p>","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"12 ","pages":"117-125"},"PeriodicalIF":1.8,"publicationDate":"2021-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3e/62/ahmt-12-117.PMC8684370.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39607541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cervicogenic Dizziness in an 11-Year-Old Girl: A Case Report.","authors":"Eric Chun-Pu Chu,&nbsp;Arnold Yu-Lok Wong","doi":"10.2147/AHMT.S341069","DOIUrl":"https://doi.org/10.2147/AHMT.S341069","url":null,"abstract":"<p><p>Cervicogenic dizziness (CGD) is a syndrome of neck pain accompanied by a false sensation of unsteadiness and dizziness due to neck pathology. An 11-year-old girl presented with neck pain and dizziness for four months. According to the patient's statement, her complaints were likely related to the prolonged smartphone use for texting. Sagittal radiograph showed cervical kyphosis, anterior wedging of several vertebrae, and mild anterolisthesis of C2 on C3 and C3 on C4. These findings might be present in as physiological variants in children. However, continuous static stress in the minor variants could aggravate biomechanical problems, such as cervicogenic dizziness. After ruling out other neurological or vestibular problems, a multicomponent approach consisted of thermal ultrasound therapy, cervical manipulation, and intermittent motorized cervicothoracic traction to release cervical complaints. Three months later, the patient reported a resolution of neck pain and dizziness. At 12-month follow-up, all radiographic metrics showed improvement, including restoration of cervical alignment and lordotic curvature. The immature growing cervical spine has unique anatomic, physiologic and biomechanical features. A static neck flexion can lead to typical injury patterns seen in this age group. This article aims to raise awareness of the potential harms of excessive smartphone use by children.</p>","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"12 ","pages":"111-116"},"PeriodicalIF":1.8,"publicationDate":"2021-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0a/b9/ahmt-12-111.PMC8636150.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39806374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of Overweight Among Primary School Children in Arba Minch Town, Southern Ethiopia, 2021.","authors":"Elias Ezo,&nbsp;Biruk Gashawbeza","doi":"10.2147/AHMT.S339671","DOIUrl":"https://doi.org/10.2147/AHMT.S339671","url":null,"abstract":"<p><strong>Background: </strong>The condition of being overweight is the abnormal excessive accumulation of fat in the body. Globally, it is a serious public health issue in both developing and developed countries.</p><p><strong>Objective: </strong>This study aims to identify determinants of overweight among primary school children in Arba Minch town, Southern Ethiopia, 2021.</p><p><strong>Methods: </strong>A school-based unmatched case control study was conducted from June 20 to 30, 2021. The total sample size was 285 (95 cases and 190 controls). Multistage sampling technique was used. Data were entered using Epi data 3.1 version and analyzed using SPSS version 24 software. Frequency, tables and figures were used. Bivariable analysis was done and variables with p <0.025 were entered to multivariable logistic regression analysis. Statistical significance was declared at p <0.05 with 95% confidence interval (CI).</p><p><strong>Results: </strong>The odds of overweight increased 19.8 times more in children whose fathers work in private business [AOR: 19.82, 95% CI: 6.21, 63.25], increased 4.8 times more in children who consume meat on more than 2 days per week [AOR: 4.75, 95% CI: 1.61, 14.03], increased 5 times more in children who consume milk on more than 2 days per week [AOR: 5.02, 95% CI: 1.80, 13.98], increased 11.9 times more in children who spend more than 6 hours sitting per day [AOR: 11.89, 95% CI: 4.13, 34.28]. And also, odds decreased by 84% in children who consume fruit on more than 2 days per week [AOR: 0.07, 95% CI: 0.03, 0.19], decreased 93% in children who consume vegetables on more than 2 days per week [AOR: 0.16, 95% CI: 0.06, 0.42], decreased 67% in children who consume cereals on more than 2 days per week [AOR: 0.33, 95% CI: 0.13, 0.84].</p><p><strong>Conclusion: </strong>Fathers working in private business, consuming fruit, vegetables, cereals, meat and milk on more than 2 days per week and sitting for more than 6 hours per day were determinants for overweight in this study. Therefore, it is better to include fruit, vegetables and cereals in dietary habits, decrease consumption of meat and milk and minimize sitting to less than 6 hours per day including school learning time.</p>","PeriodicalId":46639,"journal":{"name":"Adolescent Health Medicine and Therapeutics","volume":"12 ","pages":"99-110"},"PeriodicalIF":1.8,"publicationDate":"2021-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/20/ahmt-12-99.PMC8612828.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39680478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}