British Journal of PainPub Date : 2023-08-01Epub Date: 2023-02-23DOI: 10.1177/20494637231159502
Laura Scott, Eamon Dolan, Nita Baker, Yvonne Melia
{"title":"Exploring attitudes of healthcare professionals towards those with fibromyalgia: A Q-methodological approach.","authors":"Laura Scott, Eamon Dolan, Nita Baker, Yvonne Melia","doi":"10.1177/20494637231159502","DOIUrl":"10.1177/20494637231159502","url":null,"abstract":"<p><p>Fibromyalgia remains a difficult condition to diagnose and treat. Research suggests that this leads to frustrating experiences for service users and healthcare professionals. This has led to negative healthcare professional attitudes towards working with those with fibromyalgia. The research to date reports negative attitudes and predominantly investigates attitudes of primary care physicians. This study explores the attitudes of a range of healthcare professionals towards those diagnosed with fibromyalgia. Using Q-methodology, 27 healthcare professionals completed a sorting task and questionnaire to prioritise statements relating to a range of different attitudes towards service users. All participants significantly loaded onto three factors that explained a total of 64% of the data variance. Factor 1 reflected the attitude 'Service users with fibromyalgia are no different to other service users and I enjoy working with them'. Factor 2 reflected the attitude 'Service users with fibromyalgia are inaccurate informants of their own condition due to lack of understanding of their condition and are not likely to engage in treatments'. Factor 3 reflected the attitude 'Service users with fibromyalgia are trustworthy with a lot of clinical problems [but I lack confidence in specialist skills to support them]'. Contrary to the current literature, there appears to be supportive attitudes from healthcare professionals towards service users diagnosed with fibromyalgia. Increased specialised training, clinical exposure to working with fibromyalgia and reflective practice spaces were identified as elements that could improve healthcare professional attitudes.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"17 4","pages":"352-365"},"PeriodicalIF":1.3,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10305881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
British Journal of PainPub Date : 2023-08-01Epub Date: 2023-02-02DOI: 10.1177/20494637231153364
Ella Weik, Regula Neuenschwander, Brinn Edgington, Karin Jensen, Christine M Tipper, Tim F Oberlander
{"title":"Conditioning induced placebo-like and nocebo-like effects of thermal discomfort in adults but not in youth.","authors":"Ella Weik, Regula Neuenschwander, Brinn Edgington, Karin Jensen, Christine M Tipper, Tim F Oberlander","doi":"10.1177/20494637231153364","DOIUrl":"10.1177/20494637231153364","url":null,"abstract":"<p><strong>Introduction: </strong>Conditioning can be used to modulate the perception of pain, in the form of placebo and nocebo effects. Previous studies show inconsistent results as to whether adolescents show similar, weaker, or non-significant conditioned placebo and nocebo effects compared to effects found in adults. There are suggestions that such differences (if any) may dependent on the cues used in the thermal conditioning paradigms. Therefore, in this current study, we utilized novel, neutral 3D-shaped visual cues to implicitly induce conditioned placebo-like and nocebo-like effects in adolescents and adults.</p><p><strong>Methods: </strong>During the conditioning paradigm, distinct cues (Fribbles) were paired with low and high temperatures in 24 adults and 20 adolescents (mean age = 25.5 years). In the testing phase, these conditioned cues as well as a neutral (unconditioned) cue were presented with moderate temperatures.</p><p><strong>Results: </strong>Thermal discomfort of moderate temperatures was lower when presented with the conditioned low heat cue (placebo-like effect) and higher when thermal stimuli were presented with the high heat cue (nocebo-like effect) compared to the neutral cue. The effects were driven by adults, as neither the placebo-like nor the nocebo-like effect was significant in adolescents. The difference between adolescents and adults was not explained by differences in temperature or discomfort levels, as adults and adolescents had comparable calibrated temperatures and levels of discomfort during heat stimuli.</p><p><strong>Conclusion: </strong>Our findings suggest that thermal perception in adolescents is less influenced by conditioning to an engaging novel visual cue, compared to adults. Our work may have implications for better understanding the scope and limitations of conditioning as a key mechanism of placebo and nocebo effects in youth.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"17 4","pages":"342-351"},"PeriodicalIF":1.3,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10305885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
British Journal of PainPub Date : 2023-08-01Epub Date: 2023-03-09DOI: 10.1177/20494637231161915
Suchithra Sampath Kumar, Sidra Bano, Jagan P
{"title":"Placebo hypoalgesic and nocebo hyperalgesic effects in post-extraction patients-A cross sectional study.","authors":"Suchithra Sampath Kumar, Sidra Bano, Jagan P","doi":"10.1177/20494637231161915","DOIUrl":"10.1177/20494637231161915","url":null,"abstract":"<p><strong>Background and objectives: </strong>Pain is an unpleasant sensory and emotional experience that affects people's physical, mental, and social health. Patients at times present with postoperative pain with no clinical signs after the surgical dental procedures and adequate pharmacological management. This can be due to the amplified emotional component of the individual in their postoperative period. Hence, this study aimed to estimate the association between placebo, nocebo effects, and postoperative pain associated with tooth extraction procedures.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 301 patients attending the Department of Oral and Maxillofacial Surgery for tooth extraction. Preoperatively, the expected postoperative pain score was recorded using the \"Numerical Rating Scale\" (NRS), Anxiety and Depression were assessed using the \"Hospital Anxiety and Depression Scale\" (HADS), and Patients' expectancy regarding the treatment outcome was assessed using the \"Credibility Expectancy Questionnaire\" (CEQ). Observed postoperative pain scores at the 6th hour, 24th hour, and peak pain score of the day were recorded using the NRS.</p><p><strong>Results: </strong>There were statistically significant associations (<i>p</i> < 0.05) found between expected and observed postoperative pain, preoperative anxiety and observed postoperative pain, preoperative depression and observed postoperative pain, placebo, nocebo effects, and observed postoperative pain.</p><p><strong>Interpretation and conclusion: </strong>Our study showed a strong association between these variables suggesting that post-extraction pain is a multifaceted condition wherein pain expectation, preoperative anxiety, depression, and expectancy regarding the treatment outcome should be scrutinized before the extraction procedure.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"17 4","pages":"366-374"},"PeriodicalIF":1.3,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10304683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
British Journal of PainPub Date : 2023-08-01Epub Date: 2023-02-08DOI: 10.1177/20494637231152967
Seyyed Morteza Kazemi, Emad Kouhestani, Seyyed Mehdi Hosseini
{"title":"The effect of pregabalin on postoperative pain after anterior cruciate ligament reconstruction: A systematic review of randomized clinical trials.","authors":"Seyyed Morteza Kazemi, Emad Kouhestani, Seyyed Mehdi Hosseini","doi":"10.1177/20494637231152967","DOIUrl":"10.1177/20494637231152967","url":null,"abstract":"<p><strong>Background: </strong>Despite the enormous success of anterior cruciate ligament (ACL) reconstruction, acute neuropathic pain can develop postoperatively and is both distressing and difficult to treat once established. Pregabalin, an anticonvulsant agent that selectively affects the nociceptive process, has been used as a pain relief agent. The purpose of this systematic review of randomized controlled trials (RCTs) was to evaluate the pain control effect of pregabalin versus placebo after ACL reconstruction.</p><p><strong>Method: </strong>A search of the literature was performed from inception to June 2022, using PubMed, Scopus, Google Scholar, Web of Science, Cochrane and EBSCO. Studies considered for inclusion were RCTs that reported relevant outcomes (postoperative pain scores, cumulative opioid consumption, adverse events) following administration of pregabalin in patients undergoing ACL reconstruction.</p><p><strong>Result: </strong>Five placebo-controlled RCTs involving 272 participants met the inclusion criteria. 75 mg and 150 mg oral pregabalin was used in included trials. Two studies used a single dose of pregabalin one hour before anesthesia induction. Two studies used pregabalin 1 hour before anesthesia induction and 12 hours after. One study used daily pregabalin 7 days before and 7 days after surgery. Out of five papers, three papers found significantly lower pain intensity and cumulative opioid consumption in pregabalin group compared with placebo group. However, a decrease in pain scores was found in all trials. Pregabalin administration was associated with dizziness and nausea.</p><p><strong>Conclusion: </strong>The use of pregabalin may be a valuable asset in pain management after ACL reconstruction. However, future studies with larger sample size and longer follow-up period are required.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"17 4","pages":"332-341"},"PeriodicalIF":1.3,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10301546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
British Journal of PainPub Date : 2023-08-01Epub Date: 2023-04-26DOI: 10.1177/20494637231172674
Parmis Vafapour, Esther Murray
{"title":"Exploring the lived experiences of debilitating period pain management in the UK.","authors":"Parmis Vafapour, Esther Murray","doi":"10.1177/20494637231172674","DOIUrl":"10.1177/20494637231172674","url":null,"abstract":"<p><strong>Background: </strong>Five to ten percent of women experience period pains that disrupt their lives yet 4 in 5 women believe that their claims for their dysmenorrhea are not taken seriously. Within the process of seeking support and understanding about their pain, they face various barriers that prevent them from finding the answers they deserve.</p><p><strong>Methods: </strong>Semi-structured interviews were conducted with 8 women aged 20-28 to discuss their experiences with dysmenorrhea throughout their time since menarche.</p><p><strong>Results: </strong>Using Scheper-Hughes and Lock understanding of the mindful body, this research explores women's experiences of dysmenorrhea through their physical body (relationship with the body and needing control), the social body (cultural concepts and comparisons to others) and the body politic (medicalisation, the medical team and the transvaginal ultrasound).</p><p><strong>Conclusions: </strong>The impact of these aspects of their mindful bodies developed arguments showing how different actors had an impact on preventing them obtaining the patient-centred care they required without resistance. More must be done to honour the experience of pain women have regarding their periods, especially by healthcare professionals. There must be consistency in the way women are approached for their dysmenorrhea to prevent discrepancies of support. This must be done with clearer guidance on what is offered to women with dysmenorrhea, especially in the primary care setting.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"17 4","pages":"408-419"},"PeriodicalIF":1.3,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10305886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is England facing an opioid epidemic?","authors":"Antonia-Olivia Roberts, Georgia C Richards","doi":"10.1177/20494637231160684","DOIUrl":"https://doi.org/10.1177/20494637231160684","url":null,"abstract":"<p><p>The opioid crisis in the United States (US) is one of the most high-profile public health scandals of the 21st century with millions of people unknowingly becoming dependent on opioids. The United Kingdom (UK) had the world's highest rate of opioid consumption in 2019, and opiate-related drug poisoning deaths have increased by 388% since 1993 in England and Wales. This article explores the epidemiological definitions of public health emergencies and epidemics in the context of opioid use, misuse, and mortality in England, to establish whether England is facing an opioid crisis.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"17 3","pages":"320-324"},"PeriodicalIF":1.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10646911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
British Journal of PainPub Date : 2023-06-01Epub Date: 2023-05-30DOI: 10.1177/20494637231180485
Cassandra Macgregor, Christopher Seenan, David N Blane
{"title":"Delivering equitable pain care: Lessons from the Scottish Service Model for Chronic Pain.","authors":"Cassandra Macgregor, Christopher Seenan, David N Blane","doi":"10.1177/20494637231180485","DOIUrl":"10.1177/20494637231180485","url":null,"abstract":"","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"17 3","pages":"222-225"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10646905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
British Journal of PainPub Date : 2023-06-01Epub Date: 2022-12-23DOI: 10.1177/20494637221147185
Ryan Gl Koh, Tracy M Paul, Karlo Nesovic, Daniel West, Dinesh Kumbhare, Richard D Wilson
{"title":"Reliability and minimal detectable difference of pressure pain thresholds in a pain-free population.","authors":"Ryan Gl Koh, Tracy M Paul, Karlo Nesovic, Daniel West, Dinesh Kumbhare, Richard D Wilson","doi":"10.1177/20494637221147185","DOIUrl":"10.1177/20494637221147185","url":null,"abstract":"<p><p>The objective of this work was to evaluate the inter-rater and intra-rater reliability and minimal detectable difference (MDD) of pressure pain thresholds (PPTs) in pain-free participants with two examiners over two consecutive days in a cross-sectional study design. Examiners used a standardized method to measure and locate a specific testing site over tibialis anterior for PPT testing with a hand-held algometer. The mean of each examiner's three PPT measurements was used to calculate the intraclass correlation coefficient, inter-rater reliability, and intra-rater reliability. The minimal detectable difference (MDD) was calculated. Eighteen participants were recruited (11 female). The inter-rater reliability was 0.94 and 0.96 on day 1 and day 2, respectively. Intra-rater reliability for the examiners was 0.96 and 0.92 on day 1 and day 2, respectively. The MDD on day 1 was 1.24 kg/cm<sup>2</sup> (CI: 0.76-2.03) and the MDD on day 2 was 0.88 kg/cm<sup>2</sup> (CI: 0.54-1.43). This study demonstrates high inter- and intra-rater reliability and the MDD values for this method of pressure algometry.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"17 3","pages":"239-243"},"PeriodicalIF":1.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10646906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
British Journal of PainPub Date : 2023-06-01Epub Date: 2023-01-03DOI: 10.1177/20494637221150333
Constantino Toufexis, Molly Macgregor, Aidan Lewis, Andrew Flood
{"title":"The effects of high-definition transcranial direct current stimulation on pain modulation and stress-induced hyperalgesia.","authors":"Constantino Toufexis, Molly Macgregor, Aidan Lewis, Andrew Flood","doi":"10.1177/20494637221150333","DOIUrl":"10.1177/20494637221150333","url":null,"abstract":"<p><strong>Background: </strong>The dorsolateral prefrontal cortex (DLPFC) has been implicated in the modulation of pain-related signals. Given this involvement, manipulation of the DLPFC through transcranial direct current stimulation (tDCS) may influence internal pain modulation and decrease pain sensitivity. Acute stress is also thought to affect pain, with increased pain sensitivity observed following the presentation of an acute stressor.</p><p><strong>Methods: </strong>A total of 40 healthy adults (50% male), ranging in age from 19 to 28 years (<i>M</i> = 22.13, <i>SD</i> = 1.92), were randomly allocated to one of two stimulation conditions (active and sham). High-definition tDCS (HD-tDCS) was applied for 10 min at 2 mA, with the anode placed over the left DLPFC. Stress was induced after HD-tDCS administration using a modified version of the Trier Social Stress Test. Pain modulation and sensitivity were assessed through the conditioned pain modulation paradigm and pressure pain threshold measurements, respectively.</p><p><strong>Results: </strong>Compared to sham stimulation, active stimulation produced a significant increase in pain modulation capacity. No significant change in pain sensitivity and stress-induced hyperalgesia was observed following active tDCS.</p><p><strong>Conclusion: </strong>This research shows novel evidence that anodal HD-tDCS over the DLPFC significantly enhances pain modulation. However, HD-tDCS had no effect on pain sensitivity or stress-induced hyperalgesia. The observed effect on pain modulation after a single dose of HD-tDCS over the DLPFC is a novel finding that informs further research into the utility of HD-tDCS in the treatment of chronic pain by presenting the DLPFC as an alternative target site for tDCS-induced analgesia.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"17 3","pages":"244-254"},"PeriodicalIF":1.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10646912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A systematic review of screening diagnostic tools for trigeminal neuralgia.","authors":"Thn Teshima, J M Zakrzewska, R Potter","doi":"10.1177/20494637221146854","DOIUrl":"https://doi.org/10.1177/20494637221146854","url":null,"abstract":"<p><strong>Background and objective: </strong>Trigeminal neuralgia (TN) is a rare chronic neuropathic pain condition of sudden and severe pain, often described as an electric shock. Diagnosis is challenging for non-expert clinicians, particularly in primary care settings. We wanted to identify and assess the diagnostic accuracy of existing screening tools for TN and orofacial pain that could be used to support the diagnosis of TN in primary care.</p><p><strong>Databases and data treatment: </strong>We searched key databases (MEDLINE, ASSIA, Embase, and Web of Knowledge and PsycINFO) supplemented by citation tracking from January 1988 to 2021. We used an adapted version of the Quality of Diagnostic Accuracy Studies (QUADAS-2) to assess the methodological quality of each study.</p><p><strong>Results: </strong>Searches identified five studies, from the UK, USA and Canada; three validated self-report questionnaires; and two artificial neural networks. All screened for multiple orofacial pain diagnoses, including dentoalveolar pain, musculoskeletal pain (temporomandibular disorders) and neurological pain (trigeminal neuralgia, headache, atypical facial pain and postherpetic neuralgia). The overall quality assessment was low for one study.</p><p><strong>Conclusions: </strong>Diagnosis of TN can be challenging for non-expert clinicians. Our review found few existing screening tools to diagnose TN, and none is currently suitable to be used in primary care settings. This evidence supports the need to adapt an existing tools or to create a new tool for this purpose. The development of an appropriate screening questionnaire could assist non-expert dental and medical clinicians to identify TN more effectively and empower them to manage or refer patients for treatment more effectively.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"17 3","pages":"255-266"},"PeriodicalIF":1.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2b/d3/10.1177_20494637221146854.PMC10278451.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10646904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}