Seminars in Cardiothoracic and Vascular Anesthesia最新文献

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Length of Hospital Stay as a Performance Metric-Is That a Fair Assessment? 住院时间作为绩效指标——这是一个公平的评估吗?
IF 1.4
Seminars in Cardiothoracic and Vascular Anesthesia Pub Date : 2023-03-01 DOI: 10.1177/10892532231159723
Siddharth Pahwa, Miklos D Kertai, Benjamin Abrams, Jiapeng Huang
{"title":"Length of Hospital Stay as a Performance Metric-Is That a Fair Assessment?","authors":"Siddharth Pahwa, Miklos D Kertai, Benjamin Abrams, Jiapeng Huang","doi":"10.1177/10892532231159723","DOIUrl":"https://doi.org/10.1177/10892532231159723","url":null,"abstract":"In a healthcare sector that is constantly evolving, quality improvement has become one of the main areas of focus. Often tough to measure, the three pillars of quality improvement—structure, process, and outcome—provide the cornerstone on which advances in quality can be achieved. Length of stay (LOS) is one such often talked about outcome metric. It is desirable to have shorter lengths of stay since a longer LOS would generally indicate less efficient care and possibly higher complication rate and would in turn be less economical to the healthcare system. However, the relationship between the best possible care and LOS is seldom straightforward. This current issue of Seminars in Cardiothoracic and Vascular Anesthesia (SCVA) delves a bit into the strategies to predict and reduce hospital LOS. Two original research articles discuss predictive variables and therapeutic interventions to reduce hospital LOS, respectively. This is followed by two review articles to analyze the prevention and management of neurocognitive disorders after cardiac surgery and the management of perioperative diastolic dysfunction. A comprehensive review discusses biventricular repair from the perspective of the congenital cardiac anesthesiologist. The issue is rounded off by two interesting case reports that discuss challenging perioperative hemodynamic situations in thoracic surgery. In our firstOriginal Research article, Wang and colleagues analyzed the role of perioperative serum albumin and the albumin–bilirubin (ALBI) grade in predicting post-liver transplant LOS. In a single-institution study, they looked at 663 liver transplant recipients and concluded that a higher pre-operative serum albumin level was associated with a shorter hospital LOS. They also concluded that a lower ALBI grade, which is possibly a marker of greater hepatic synthetic activity, was associated with shorter hospital and intensive care unit (ICU) LOS in patients with a low Model for End Stage Liver Disease–sodium (MELD-Na) score. However, there was no difference in operative mortality across the ALBI grades. Higher MELD-Na scores are known to be associated with worse postoperative outcomes and would alert clinicians to the possibility of longer hospital and ICU LOS. The ability to risk stratify patients that are otherwise “low risk”with lowerMELD-Na scores based on ALBI grade makes this paper pertinent and may pave the way for future trials to investigate the role of ALBI in this subset of patients. Minimally invasive valve surgery has continued to evolve and can now be performed safely with shorter ICU and hospital LOS, while keeping the quality of the operation similar to that performed through a full sternotomy. Postoperative pain has been one of the barriers to a faster recovery and earlier discharge following minimally invasive valve surgery, and this may be because of extensive rib retraction and division of intercostal muscles associated with the surgical procedure. In the second Original","PeriodicalId":46500,"journal":{"name":"Seminars in Cardiothoracic and Vascular Anesthesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10848481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Retrospective Study of the Role of Perioperative Serum Albumin and the Albumin-Bilirubin Grade in Predicting Post-Liver Transplant Length of Stay. 围手术期血清白蛋白及白蛋白-胆红素分级预测肝移植术后住院时间的回顾性研究。
IF 1.4
Seminars in Cardiothoracic and Vascular Anesthesia Pub Date : 2023-03-01 DOI: 10.1177/10892532221141138
Ryan Wang, Daniel Katz, Hung-Mo Lin, Yuxia Ouyang, Jonathan Gal, Sumanth Suresh, Ismail Labgaa, Parissa Tabrizian, Samuel Demaria, Jeron Zerillo, Natalie K Smith
{"title":"A Retrospective Study of the Role of Perioperative Serum Albumin and the Albumin-Bilirubin Grade in Predicting Post-Liver Transplant Length of Stay.","authors":"Ryan Wang,&nbsp;Daniel Katz,&nbsp;Hung-Mo Lin,&nbsp;Yuxia Ouyang,&nbsp;Jonathan Gal,&nbsp;Sumanth Suresh,&nbsp;Ismail Labgaa,&nbsp;Parissa Tabrizian,&nbsp;Samuel Demaria,&nbsp;Jeron Zerillo,&nbsp;Natalie K Smith","doi":"10.1177/10892532221141138","DOIUrl":"https://doi.org/10.1177/10892532221141138","url":null,"abstract":"<p><strong>Introduction: </strong>Serum albumin's association with liver transplant outcomes has been investigated with mixed findings. This study aimed to evaluate perioperative albumin level, independently and as part of the albumin-bilirubin (ALBI) grade, as a predictor of post-liver transplant hospital and intensive care unit (ICU) length of stay (LOS).</p><p><strong>Methods: </strong>Adult liver-only transplant recipients at our institution from September 2011 to May 2019 were included in this retrospective study. Repeat transplants were excluded. Demographic, laboratory, and hospital course data were extracted from an institutional data warehouse. Negative binomial regression was used to assess the association of LOS with ALBI grade, age, BMI, ASA score, Elixhauser comorbidity index, MELD-Na, warm ischemia time, units of platelets and cryoprecipitate transfused, and preoperative serum albumin.</p><p><strong>Results: </strong>Six hundred and sixty-three liver transplant recipients met inclusion criteria. The median preoperative serum albumin was 3.1 [2.6-3.6] g/dL. The median postoperative ICU and hospital LOS were 3.8 [2.4-6.8] and 12 [8-20] days, respectively. Preoperative serum albumin predicted hospital but not ICU LOS (ratio .9 [95% confidence interval (CI) .84-.99], <i>P</i> = .03, hospital LOS vs ratio .92 [95% CI 0.84-1.02], <i>P</i> = .10, ICU LOS). For patients with MELD-Na ≤ 20, ALBI grade-3 predicted longer hospital and ICU LOS (ratio 1.40 [95% CI 1.18-1.66], <i>P</i> < .001, hospital LOS vs ratio 1.62 [95% CI 1.32-1.99], <i>P</i> < .001, ICU LOS). These associations were not significant for patients with MELD-Na > 20.</p><p><strong>Conclusions: </strong>Serum albumin predicted post-liver transplant hospital LOS. ALBI grade-3 predicted increased hospital and ICU LOS in low MELD-Na recipients.</p>","PeriodicalId":46500,"journal":{"name":"Seminars in Cardiothoracic and Vascular Anesthesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9339394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Thoracic Interfascial Plane Blocks and Outcomes After Minithoracotomy for Valve Surgery. 小开胸主动脉瓣手术后胸筋膜间平面阻滞及预后。
IF 1.4
Seminars in Cardiothoracic and Vascular Anesthesia Pub Date : 2023-03-01 DOI: 10.1177/10892532221136386
Sreekanth R Cheruku, Amanda A Fox, Hooman Heravi, Neelan Doolabh, Jennifer Davis, Jenny He, Christopher Deonarine, Lauren Bereuter, Joan Reisch, Farzin Ahmed, Lisa Skariah, Anthony Machi
{"title":"Thoracic Interfascial Plane Blocks and Outcomes After Minithoracotomy for Valve Surgery.","authors":"Sreekanth R Cheruku,&nbsp;Amanda A Fox,&nbsp;Hooman Heravi,&nbsp;Neelan Doolabh,&nbsp;Jennifer Davis,&nbsp;Jenny He,&nbsp;Christopher Deonarine,&nbsp;Lauren Bereuter,&nbsp;Joan Reisch,&nbsp;Farzin Ahmed,&nbsp;Lisa Skariah,&nbsp;Anthony Machi","doi":"10.1177/10892532221136386","DOIUrl":"https://doi.org/10.1177/10892532221136386","url":null,"abstract":"<p><p><i>Introduction.</i> Thoracic interfascial plane blocks are increasingly used for pain management after minimally invasive thoracotomy for valve repair and replacement procedures. We hypothesized that the addition of these blocks to the intercostal nerve block injected by the surgeon would further reduce pain scores and opioid utilization. <i>Methods.</i> In this retrospective cohort study, 400 consecutive patients who underwent minimally invasive thoracotomy for mitral or aortic valve replacement and were extubated within 2 hours of surgery were enrolled. The maximum pain score and opioid utilization on the day of surgery and other outcome variables were compared between patients who received interfascial plane blocks and those who did not. <i>Results.</i>193 (48%) received at least one interfascial plane block while 207 (52%) received no interfascial plane block. Patients who received a thoracic interfascial plane block had a maximum VAS score on the day of surgery (mean 7.4 ± 2.5) after the block was administered which was significantly lower than patients in the control group who did not receive the block (mean 7.9 ± 2.2) (<i>P</i> = .02). Opioid consumption in the interfascial plane block group on the day of surgery was not significantly different from the control group. <i>Conclusion.</i> Compared to intercostal blocks alone, the addition of thoracic interfascial plane blocks was associated with a modest reduction in maximum VAS score on the day of surgery. However, no difference in opioid consumption was noted. Patients who received interfascial plane blocks also had decreased blood transfusion requirements and a shorter hospital length of stay.</p>","PeriodicalId":46500,"journal":{"name":"Seminars in Cardiothoracic and Vascular Anesthesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10775789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Perioperative Neurocognitive Disorders in Adults Requiring Cardiac Surgery: Screening, Prevention, and Management. 需要心脏手术的成人围手术期神经认知障碍:筛查、预防和管理。
IF 1.4
Seminars in Cardiothoracic and Vascular Anesthesia Pub Date : 2023-03-01 DOI: 10.1177/10892532221127812
Kimberly F Rengel, Christina S Boncyk, Daniella DiNizo, Christopher G Hughes
{"title":"Perioperative Neurocognitive Disorders in Adults Requiring Cardiac Surgery: Screening, Prevention, and Management.","authors":"Kimberly F Rengel,&nbsp;Christina S Boncyk,&nbsp;Daniella DiNizo,&nbsp;Christopher G Hughes","doi":"10.1177/10892532221127812","DOIUrl":"https://doi.org/10.1177/10892532221127812","url":null,"abstract":"<p><p>Neurocognitive changes are the most common complication after cardiac surgery, ranging from acute postoperative delirium to prolonged postoperative neurocognitive disorder. Changes in cognition are distressing to patients and families and associated with worse outcomes overall. This review outlines definitions and diagnostic criteria, risk factors for, and mechanisms of Perioperative Neurocognitive Disorders and offers strategies for preoperative screening and perioperative prevention and management of neurocognitive complications.</p>","PeriodicalId":46500,"journal":{"name":"Seminars in Cardiothoracic and Vascular Anesthesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10776098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Airway and Hemodynamic Considerations for the Anesthetic Management of an Intraluminal Tracheal Plasmacytoma. 腔内气管浆细胞瘤麻醉处理的气道和血流动力学考虑。
IF 1.4
Seminars in Cardiothoracic and Vascular Anesthesia Pub Date : 2023-03-01 DOI: 10.1177/10892532221140235
Joseph E Morabito, Colby G Simmons, Giorgio Zanotti, John D Mitchell, Karsten Bartels, Barbara J Wilkey
{"title":"Airway and Hemodynamic Considerations for the Anesthetic Management of an Intraluminal Tracheal Plasmacytoma.","authors":"Joseph E Morabito,&nbsp;Colby G Simmons,&nbsp;Giorgio Zanotti,&nbsp;John D Mitchell,&nbsp;Karsten Bartels,&nbsp;Barbara J Wilkey","doi":"10.1177/10892532221140235","DOIUrl":"https://doi.org/10.1177/10892532221140235","url":null,"abstract":"<p><p>Central airway obstruction due to tracheal tumors presents unique challenges to the anesthesiologist. We present the case of a 44-year-old male taken to the OR for biopsy and resection of an undiagnosed tracheal mass. Intraoperative management was complicated by bleeding and significant hemodynamic instability, necessitating rapid surgical and anesthetic intervention. This ultimately led to abortion of surgical resection. Pathologic examination revealed a primary tracheal plasmacytoma, a rare type of tracheal tumor. Here, we describe anesthetic and hemodynamic considerations for a tracheal plasmacytoma. We discuss the approach to airway management in variable intrathoracic tracheal obstruction and the unpredictability of tracheal tumors.</p>","PeriodicalId":46500,"journal":{"name":"Seminars in Cardiothoracic and Vascular Anesthesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10781422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Managing Diastolic Dysfunction Perioperatively. 围手术期舒张功能不全的处理。
IF 1.4
Seminars in Cardiothoracic and Vascular Anesthesia Pub Date : 2023-03-01 DOI: 10.1177/10892532221142441
Theodore J Cios, John C Klick, S Michael Roberts
{"title":"Managing Diastolic Dysfunction Perioperatively.","authors":"Theodore J Cios,&nbsp;John C Klick,&nbsp;S Michael Roberts","doi":"10.1177/10892532221142441","DOIUrl":"https://doi.org/10.1177/10892532221142441","url":null,"abstract":"<p><p>Preoperative cardiac evaluation is a cornerstone of the practice of anesthesiology. This consists of a thorough history and physical attempting to elucidate signs and symptoms of heart failure, angina or anginal equivalents, and valvular heart disease. Current guidelines rarely recommend preoperative echocardiography in the setting of an adequate functional capacity. Many patients may have poor functional capacity and/or have medical history such that echocardiographic data is available for review. Much focus is often placed on evaluating major valvular abnormalities and systolic function as measured by ejection fraction, but a key impactful component is often overlooked-diastolic function. A diagnosis of diastolic heart failure is an independent predictor of mortality and is not uncommon in patients with normal systolic function. This narrative review addresses the clinical relevance and management of diastolic dysfunction in the perioperative setting.</p>","PeriodicalId":46500,"journal":{"name":"Seminars in Cardiothoracic and Vascular Anesthesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/66/82/10.1177_10892532221142441.PMC9968995.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10793848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Perioperative Circulatory Support and Management for Lung Transplantation: A Case-Based Review. 肺移植围手术期循环支持和管理:一项基于病例的回顾。
IF 1.4
Seminars in Cardiothoracic and Vascular Anesthesia Pub Date : 2023-03-01 DOI: 10.1177/10892532221134574
Hong Liang, Ashley V Fritz, Archer K Martin
{"title":"Perioperative Circulatory Support and Management for Lung Transplantation: A Case-Based Review.","authors":"Hong Liang,&nbsp;Ashley V Fritz,&nbsp;Archer K Martin","doi":"10.1177/10892532221134574","DOIUrl":"https://doi.org/10.1177/10892532221134574","url":null,"abstract":"<p><p>Lung transplantation (LTx) historically was performed with cardiopulmonary bypass (CPB) or Off-pump. Recent data suggest an increased interest in extracorporeal membrane oxygenation (ECMO) as perioperative circulatory support by many lung transplantation centers worldwide. However, there are no established guidelines for anesthetic management for LTx. We present a patient with a history of systemic sclerosis and interstitial lung disease complicated by acute onset of systemic pulmonary hypertension and right heart failure undergoing LTx. We aim to discuss perioperative circulatory support, including ECMO bridge to LTx, and how best to consider the varied intraoperative strategies of CPB vs ECMO vs off-pump during LTx, intraoperative maintenance, and coagulation management.</p>","PeriodicalId":46500,"journal":{"name":"Seminars in Cardiothoracic and Vascular Anesthesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10775777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Review of Biventricular Repair for the Congenital Cardiac Anesthesiologist. 先天性心脏麻醉师双心室修复术综述。
IF 1.4
Seminars in Cardiothoracic and Vascular Anesthesia Pub Date : 2023-03-01 DOI: 10.1177/10892532221143880
Sean J Davies, James A DiNardo, Sitaram M Emani, Morgan L Brown
{"title":"A Review of Biventricular Repair for the Congenital Cardiac Anesthesiologist.","authors":"Sean J Davies,&nbsp;James A DiNardo,&nbsp;Sitaram M Emani,&nbsp;Morgan L Brown","doi":"10.1177/10892532221143880","DOIUrl":"https://doi.org/10.1177/10892532221143880","url":null,"abstract":"<p><p>The management of children with a borderline ventricle has been debated for many years. The pursuit of a biventricular repair in these children aims to avoid the long-term sequelae of single ventricle palliation. There is a lack of anesthesia literature relating to the care of this complex heterogenous patient population. Anesthesiologists caring for these patients should have an understanding on the many different forms of physiology and the impact on provision of anesthesia and hemodynamic parameters, the goals of biventricular staging and completion as well as the pre-operative, intra-operative, and post-operative considerations relating to this high-risk group of patients.</p>","PeriodicalId":46500,"journal":{"name":"Seminars in Cardiothoracic and Vascular Anesthesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10781922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Bleeding Complications from Transesophageal Echocardiography for Liver Transplantation: A Systematic Review. 经食管超声心动图检查肝移植出血并发症的系统回顾。
IF 1.4
Seminars in Cardiothoracic and Vascular Anesthesia Pub Date : 2022-12-01 Epub Date: 2022-08-20 DOI: 10.1177/10892532221122666
W Jonathan Dunkman, David A Williams, Michael W Manning
{"title":"Bleeding Complications from Transesophageal Echocardiography for Liver Transplantation: A Systematic Review.","authors":"W Jonathan Dunkman,&nbsp;David A Williams,&nbsp;Michael W Manning","doi":"10.1177/10892532221122666","DOIUrl":"https://doi.org/10.1177/10892532221122666","url":null,"abstract":"<p><p>Transesophageal echocardiography (TEE) for liver transplant has historically been avoided due to concern it may cause bleeding from esophageal varices. However, several recent studies, as well as increasing clinical experience, have indicated that it may be safe in many circumstances. We performed a systematic review of the literature to identify and summarize studies reporting complications in patients having TEE during liver transplant. Studies were identified by searching relevant key terms on PubMed as well as citation searching in relevant reviews. We identified 6 studies between 1996 and 2015 which evaluated complications of TEE during liver transplant. They reported an overall bleeding complication rate between .3% and 2.8% and a major bleeding complication rate between .0% and .8%. Most of the major bleeds had identifiable high-risk features such as recent variceal bleeding or banding. Review of the literature suggests that TEE may be safely used in patients undergoing liver transplantation, even with known varices, with a complication rate similar to that of all patients undergoing TEE. However, the risks of TEE may outweigh the potential benefits among patients undergoing liver transplant with particular high-risk features.</p>","PeriodicalId":46500,"journal":{"name":"Seminars in Cardiothoracic and Vascular Anesthesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40716174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
A Randomized Pilot Study Assessing if SEDLine Monitoring During Induction of Surgical Patients is Associated With Reduced Dosage of Administered Induction Agents. 一项评估外科患者诱导过程中SEDLine监测是否与诱导药物剂量减少相关的随机试验研究。
IF 1.4
Seminars in Cardiothoracic and Vascular Anesthesia Pub Date : 2022-12-01 Epub Date: 2022-10-05 DOI: 10.1177/10892532221130660
Martin Krause, Albert Nguyen, Orestes O'Brien, Swapnil Khoche, Ulrich Schmidt
{"title":"A Randomized Pilot Study Assessing if SEDLine Monitoring During Induction of Surgical Patients is Associated With Reduced Dosage of Administered Induction Agents.","authors":"Martin Krause,&nbsp;Albert Nguyen,&nbsp;Orestes O'Brien,&nbsp;Swapnil Khoche,&nbsp;Ulrich Schmidt","doi":"10.1177/10892532221130660","DOIUrl":"https://doi.org/10.1177/10892532221130660","url":null,"abstract":"<p><p><i>Background</i>. Intubations, especially in emergent settings, carry a high risk of hemodynamic instability with potentially catastrophic outcomes. Weight-based dosing of induction drugs can be inappropriately high for elective or emergent intubations and lead to hemodynamic instability. We hypothesized that monitoring the patient state index of SEDLine monitors (Masimo, Irvine, CA) would decrease the dose of induction drugs in the operating room during elective intubations.<i>Methods</i>. In this randomized study, SEDLine monitoring was provided to the intervention group but not to the control group during the induction of anesthesia in the operating room. Anesthesia providers in the intervention group were advised to titrate induction drugs to a Patient State Index of <50 before proceeding with intubation. The primary outcome was the induction dose of propofol and etomidate per kilogram normalized to propofol dose equivalents. Secondary outcomes included supplemental doses of ketamine, midazolam, fentanyl, phenylephrine, and ephedrine per kg, time from induction to intubation, administration of additional propofol or vasopressors after induction, mean arterial pressure <b>≥</b> or <65 mmHg, and lowest mean arterial pressure post-induction.<i>Results</i>. We found no significant difference in propofol equivalents between groups (<i>P</i> = .41). Using a SEDLine decreased the odds that a patient would require vasopressors during induction (odds ratio of .39 [95% confidence interval, .15-.98]).<i>Conclusion</i>. SEDLine monitoring during induction did not decrease dosing of the induction drugs etomidate and propofol but decreased the odds of receiving vasopressors. Further studies are warranted to assess the utility of processed electroencephalography in emergent intubations outside of the operating room.</p>","PeriodicalId":46500,"journal":{"name":"Seminars in Cardiothoracic and Vascular Anesthesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33505568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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