G. Ballout, R. Berge Ramos, L. Gómez-López, M. López-Baamonde
{"title":"Vía aérea difícil por fibromas esclerosantes múltiples en paciente con síndrome de Cowden","authors":"G. Ballout, R. Berge Ramos, L. Gómez-López, M. López-Baamonde","doi":"10.1016/j.redar.2024.03.002","DOIUrl":"10.1016/j.redar.2024.03.002","url":null,"abstract":"","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"72 3","pages":"Article 101622"},"PeriodicalIF":0.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141055091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Martins de Carvalho, P. Costa Antunes, A. Nunes Miranda, J. Marques Vinagre
{"title":"Neumoencéfalo tras técnica espinal-epidural combinada: informe de caso","authors":"I. Martins de Carvalho, P. Costa Antunes, A. Nunes Miranda, J. Marques Vinagre","doi":"10.1016/j.redar.2024.03.008","DOIUrl":"10.1016/j.redar.2024.03.008","url":null,"abstract":"<div><div>Pneumocephalus refers to the presence of air within the intracranial cavity, and albeit its occurrence following neuraxial techniques is rare, it is commonly associated with a loss of resistance to air technique.</div><div>This case report describes a parturient who underwent neuraxial analgesia for pain management during labour. Epidural space identification with loss of resistance to saline technique was used and she went on to develop a symptomatic pneumocephalus.</div><div>The pneumocephalus had an atypical presentation without immediate headache but with a sudden change in consciousness, likely due to an increase in intracranial pressure following migration of air into the intracranial cavity through the ventricular system.</div><div>Although in most cases it is benign, asymptomatic, and self-limiting, early diagnosis is helpful as treatment with supplemental oxygen can speed recovery. In this case, due to its atypical and sudden presentation, supportive treatment was essential for the prognosis of both mother and baby.</div></div>","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"72 3","pages":"Article 101628"},"PeriodicalIF":0.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141394578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Ripollés-Melchor , A.V. Espinosa , P. Fernández-Valdes-Bango , R. Navarro-Pérez , A. Abad-Motos , J.V. Lorente , M.J. Colomina , A. Abad-Gurumeta , M.I. Monge-García
{"title":"Terapia hemodinámica guiada por objetivos intraoperatoria focalizada en parámetros de presión arterial y flujo mediante técnicas no calibradas de contorno del pulso: metaanálisis de ensayos controlados aleatorizados","authors":"J. Ripollés-Melchor , A.V. Espinosa , P. Fernández-Valdes-Bango , R. Navarro-Pérez , A. Abad-Motos , J.V. Lorente , M.J. Colomina , A. Abad-Gurumeta , M.I. Monge-García","doi":"10.1016/j.redar.2024.501653","DOIUrl":"10.1016/j.redar.2024.501653","url":null,"abstract":"<div><h3>Background</h3><div>Goal-directed haemodynamic therapy (GDHT) aims to optimize haemodynamic variables. However, its effectiveness in reducing postoperative complications in major abdominal surgery, particularly when targeting both arterial pressure and flow variables, remains unclear. This meta-analysis addresses this by evaluating GDHT using uncalibrated pulse contour (uPC) methods.</div></div><div><h3>Methods</h3><div>We conducted a systematic review and meta-analysis of randomized controlled trials (RCT) in adult patients undergoing major abdominal surgery who received GDHT using uncalibrated pulse contour (uPC) methods for cardiac output monitoring, with predefined targets for both blood flow and blood pressure. The primary outcome was postoperative complications; secondary outcomes included postoperative acute kidney injury (AKI), hospital length of stay (EH), intraoperative fluid administration and mortality.</div></div><div><h3>Results</h3><div>Initial search retrieved 860 reports, with 12 RCTs (1367 patients) meeting the inclusion criteria. Our meta-analysis showed a significant reduction in postoperative complications (RR: 0.78; 95%<!--> <!-->CI: 0.68-0.90), AKI (RR: 0.7; 95%<!--> <!-->CI: 0.51-0.97), and hospital LOS (SMD: −0.30; 95%<!--> <!-->CI: −0.54 to −0.06) with uPC-guided GDHT. No significant differences were observed in intraoperative fluid volume and mortality.</div></div><div><h3>Conclusions</h3><div>Implementing GDHT in major abdominal surgery with predefined arterial pressure and blood flow targets significantly reduces postoperative morbidity and hospital EH without increasing intraoperative fluid administration.</div></div>","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"72 3","pages":"Article 501653"},"PeriodicalIF":0.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Freitas Martín, J. Veganzones Ramos, S. Díaz Carrasco, L. Suárez Gonzalo
{"title":"Hipoxemia refractaria durante la terapia de eliminación extracorpórea de CO2: informe de un caso y revisión de la literatura","authors":"S. Freitas Martín, J. Veganzones Ramos, S. Díaz Carrasco, L. Suárez Gonzalo","doi":"10.1016/j.redar.2025.501769","DOIUrl":"10.1016/j.redar.2025.501769","url":null,"abstract":"<div><div>Extracorporeal carbon dioxide removal is increasingly used in clinical practice as a means of facilitating protective mechanical ventilation and reducing the risk of ventilator-induced lung injury in patients with acute respiratory distress syndrome. In some cases, however, extracorporeal carbon dioxide removal can worsen hypoxaemia due to various pathophysiological mechanisms that need to be taken into consideration. We report a case of refractory hypoxaemia that required interruption of extracorporeal carbon dioxide removal therapy.</div></div>","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"72 5","pages":"Article 501769"},"PeriodicalIF":0.9,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Varela Durán , R. Navarro Pérez , O. de la Varga Martínez , S. Montesinos Fadrique , E. Tamayo Gómez , R. Badenes Quiles
{"title":"Estudio de cohorte multicéntrico sobre la prevalencia del delirium postoperatorio a las 48 h de la cirugía: protocolo de «estudio DELPO»","authors":"M. Varela Durán , R. Navarro Pérez , O. de la Varga Martínez , S. Montesinos Fadrique , E. Tamayo Gómez , R. Badenes Quiles","doi":"10.1016/j.redar.2025.501727","DOIUrl":"10.1016/j.redar.2025.501727","url":null,"abstract":"","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"72 5","pages":"Article 501727"},"PeriodicalIF":0.9,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Herrero García , S.E. Denis Filippini , A. de la Fuente , E. Choolani Bhojwani , J. Sánchez González , M. Bailón Cuadrado , S. Veleda Belanche , V. Simó Fernández , J.A. García Erce , C. Aldecoa Álvarez-Santullano
{"title":"Hemoglobina preoperatoria como factor predictivo de morbilidad intrahospitalaria y mortalidad a 5 años en el cáncer colorrectal","authors":"A. Herrero García , S.E. Denis Filippini , A. de la Fuente , E. Choolani Bhojwani , J. Sánchez González , M. Bailón Cuadrado , S. Veleda Belanche , V. Simó Fernández , J.A. García Erce , C. Aldecoa Álvarez-Santullano","doi":"10.1016/j.redar.2024.501723","DOIUrl":"10.1016/j.redar.2024.501723","url":null,"abstract":"<div><h3>Background</h3><div>Colorectal cancer (CRC) is the third most diagnosed cancer worldwide. Preoperative anaemia is common in CRC patients undergoing surgery.</div></div><div><h3>Objective</h3><div>This study assesses the prevalence of preoperative anaemia and its impact on postoperative outcomes, and aims to establish a cut-off point for increased morbidity and mortality in a large prospective single centre cohort.</div></div><div><h3>Methods</h3><div>We conducted a retrospective cohort study of 1105 CRC patients (2014-2021). Anaemia was defined as per WHO criteria. Multivariate logistic regression and Kaplan-Meier survival analyses were used. The statistical significance level was set at <<!--> <!-->.05.</div></div><div><h3>Results</h3><div>Preoperative anaemia was present in 45.3% of patients, and was associated with a higher incidence of perioperative complications (OR: 2.76; <em>P</em> <!-->=<!--> <!-->.011) and lower 5-year survival (73% vs 87%, p<!--> <!--><<!--> <!-->.001.</div></div><div><h3>Discussion/conclusions</h3><div>Preoperative anaemia, even when mild, is associated with a higher rate of complications, longer hospital stay, and a greater risk of 5-year mortality.</div></div>","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"72 5","pages":"Article 501723"},"PeriodicalIF":0.9,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Consideraciones anestésicas en el manejo perioperatorio del paciente con angioedema hereditario FXII","authors":"P. García Robledo , J.C. García Ortiz","doi":"10.1016/j.redar.2025.501732","DOIUrl":"10.1016/j.redar.2025.501732","url":null,"abstract":"<div><div>Hereditary angioedema (HAE) is of interest to anaesthesiologists due to its impact on perioperative management. HAE manifests as episodic, self-limiting oedema in the deep subcutaneous or submucosal tissue that can be fatal if it involves the airway. It is usually caused by C1 esterase inhibitor deficiency. HAE episodes can be triggered by trauma, including surgical and medical procedures associated with mechanical trauma. Our understanding of HAE has evolved in recent years following the development of new genetic sequencing technologies that have made it possible to differentiate variants with normal C1 esterase inhibitor levels. In Spain, the most frequent of these is HAE due to a mutation in FXII, previously known as HAE type <span>iii</span>. There are as yet no good quality studies on perioperative management and treatment of these patients. The admission of a patient with FXII-HAE for labour induction has given us the opportunity to review the perioperative management of these cases.</div></div>","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"72 5","pages":"Article 501732"},"PeriodicalIF":0.9,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impacto medioambiental de los anestésicos volátiles en un hospital docente de alta complejidad de 2019 a 2022: análisis cuantitativo","authors":"A.M. Obando Rondón , C.A. Triana-Schöonewolff , J.D. Guerra Toro , J.F. Parada-Márquez , N.A. Avila Ardila , A.F. Zuluaga Zuluaga , M.C. Cardona-Lozano","doi":"10.1016/j.redar.2024.501659","DOIUrl":"10.1016/j.redar.2024.501659","url":null,"abstract":"<div><h3>Background</h3><div>The healthcare sector emits 5% of greenhouse gases worldwide, inhaled anesthetic agents have contributed to this effect for years. Other countries measured and limited their use, leading to positive environmental changes. There is a lack of data on Colombia. This project aims to evaluate the environmental impact of desflurane, isoflurane, and sevoflurane between 2019 and 2022 in a hospital in Bogota.</div></div><div><h3>Methods</h3><div>A retrospective exploration of inhaled anesthetic agents use was conducted using our hospital's pharmacy inventory between 2019 and 2022. Oracle software tools were used, along with the amount of anesthetics dispensed by the pharmacy. The CO<sub>2</sub> equivalent was calculated in kilograms using the global warming potential at 20 and 100 years.</div></div><div><h3>Results</h3><div>A total of 743<!--> <!-->kg of inhaled anesthetic agents was administered between 2019 and 2022. Sevoflurane accounted for 265.7<!--> <!-->kg, desflurane for 473.9<!--> <!-->kg, while isoflurane was used in smaller quantities. There was a change in the trend between 2019/2020 and 2021/2022, with an increase of 69.3<!--> <!-->kg in sevoflurane use and a decrease of 86.2<!--> <!-->kg in desflurane use. The CO<sub>2</sub> emissions from desflurane decreased from 190.7 to 131.9<!--> <!-->t over 20 years and from 711 to 492<!--> <!-->t over 100 years.</div></div><div><h3>Conclusions</h3><div>The use of sevoflurane increased by 70%, whereas that of desflurane decreased by 31%. CO<sub>2</sub> emissions were reduced by 557<!--> <!-->t in 20 years and 210<!--> <!-->t in 100 years. The environmental impact of sevoflurane is 97% lower than desflurane in our OR's.</div></div>","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"72 2","pages":"Article 501659"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143167727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. González-Delgado , M. Vives , P. Monedero , A. Aldaz
{"title":"Uso de vancomicina y lesión renal aguda en pacientes críticos con sepsis o shock séptico: cohorte observacional retrospectiva","authors":"D. González-Delgado , M. Vives , P. Monedero , A. Aldaz","doi":"10.1016/j.redar.2024.501657","DOIUrl":"10.1016/j.redar.2024.501657","url":null,"abstract":"<div><h3>Introduction</h3><div>The independent association of vancomycin with Acute Kidney Injury (AKI) in the critically ill patient with sepsis or septic Shock is controversial.</div><div>The aim of this study was to evaluate the incidence of AKI in a cohort of patients with sepsis or septic Shock with an adequate and strict monitoring of vancomycin, guided by the area under the concentration-time curve in relation to the minimum inhibitory concentration (AUC/MIC ratio).</div></div><div><h3>Material and methods</h3><div>Retrospective cohort study on 106 patients admitted to the ICU with a diagnosis of sepsis or septic shock with vancomycin treatment, consecutively from January 2017 to December 2019.</div><div>AKI was defined according to Kidney Disease Improving Global Outcomes criteria. Risk factors associated with AKI were determined by multivariable logistic regression analysis.</div></div><div><h3>Results</h3><div>In our cohort, 28 patients out of 106 (26%) developed AKI. ICU and 30-day mortality were 18% and 22%, respectively. After multivariable logistic regression adjusted analysis, chronic liver disease was associated with AKI.</div></div><div><h3>Conclusion</h3><div>In our retrospective cohort study on critical patients with sepsis and septic shock, treated with vancomycin adjusting the dose guided by a pharmacokinetic/pharmacodynamic monitoring to achieve the target AUC<sub>0-24</sub>/CMI ratio, the incidence of AKI was 26%.</div></div>","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"72 2","pages":"Article 501657"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143167729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Velasco , A. Calle , J. Coronel , A. Gallo , A. Reyes , M. Portas , L. Bermejo , A. Giménez , A. Ribed , M. Zaballos
{"title":"Estudio de cohortes para evaluar el patrón de prescripción analgésica en pacientes adultos intervenidos en cirugía mayor ambulatoria","authors":"L. Velasco , A. Calle , J. Coronel , A. Gallo , A. Reyes , M. Portas , L. Bermejo , A. Giménez , A. Ribed , M. Zaballos","doi":"10.1016/j.redar.2024.501664","DOIUrl":"10.1016/j.redar.2024.501664","url":null,"abstract":"<div><h3>Introduction</h3><div>Postoperative pain in ambulatory surgery (AS) continues to be a recurrent problem despite anesthetic and surgical advances. Analgesic prescription and follow-up by patients at home may be a determining factor. Our objective was to evaluate analgesic prescription and its impact on the intensity of postoperative pain at 24<!--> <!-->h and 7<!--> <!-->days in an AS unit.</div></div><div><h3>Methods</h3><div>Retrospective cohort study of patients undergoing AS. Anthropometric data, ASA classification, surgery, anesthesia, analgesic prescription and postoperative pain. A telephone call was made by nurses to evaluate the DAP at 24<!--> <!-->h and one week after surgery.</div></div><div><h3>Results</h3><div>A total of 875 patients, 62% women, aged 50<!--> <!-->±<!--> <!-->17 years, were studied. Orthopedic (45.4%); head and neck (19.5%); general (10.6%); vascular (11.9%); plastic (2.4%) and gynecological (10.2%) surgery was performed. Multimodal analgesia was prescribed: 83.7%, combination of nonsteroidal anti-inflammatory drug (NSAID) +<!--> <!-->paracetamol +<!--> <!-->metamizole: 70.79%; opioid +<!--> <!-->paracetamol or NSAID or in monotherapy: 13.1%; monotherapy with paracetamol (15%) or NSAID (1.15%). Some 62.45% were prescribed «if pain» and 61.87% had rescue analgesia. At 24<!--> <!-->h the median (IQR) of pain on the self-assessing verbal scale was 3 (2 to 5) and at one week 2 (0 to 4). The presence of moderate-severe pain was 46% at 24<!--> <!-->h and 31% at one week after surgery.</div></div><div><h3>Conclusions</h3><div>Our results show great variability in analgesic prescription with insufficient control of postoperative pain in ambulatory surgery. Although the multimodal analgesic strategy has been widely used, opioid prescription has been insufficient in surgeries associated with moderate to severe pain.</div></div>","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"72 2","pages":"Article 501664"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143167734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}