Rambam Maimonides Medical Journal最新文献

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Changes in the Management of Common Bile Duct Stones: 1980 to Date. 胆总管结石治疗的变化:1980年至今。
IF 1.5
Rambam Maimonides Medical Journal Pub Date : 2024-04-28 DOI: 10.5041/RMMJ.10521
Ruth Stalnikowicz, Jochanan Benbassat
{"title":"Changes in the Management of Common Bile Duct Stones: 1980 to Date.","authors":"Ruth Stalnikowicz, Jochanan Benbassat","doi":"10.5041/RMMJ.10521","DOIUrl":"10.5041/RMMJ.10521","url":null,"abstract":"<p><strong>Objective: </strong>To compare the results of treating patients with common bile duct (CBD) stones by endoscopic sphincterotomy (ES), surgical exploration, or a combination of ES and surgical CBD exploration (the rendezvous technique).</p><p><strong>Methods: </strong>A narrative review of the literature.</p><p><strong>Summary of data: </strong>Before 1990, 17 cohort studies indicated that ES cleared CBD stones in 92.0% of patients, with a mortality rate of 1.5%. Surgery removed CBD stones in 90.2% of patients, with a 2.1% mortality rate. A single randomized controlled trial in 1987 showed that ES removed CBD stones in 91% of 55 patients, with a 3.6% mortality rate and a 27% complication rate, whereas surgical CBD exploration removed CBD stones in 92%, with a 1.8% mortality rate and a 22% complication rate. Since 1991, 26 randomized controlled trials have shown that laparoscopic-ES rendezvous is as effective as ES alone and laparoscopic surgery alone but is associated with fewer complications, a reduced need for additional procedures, and a shorter hospital stay.</p><p><strong>Conclusions: </strong>A laparoscopic-ES rendezvous appears to be the optimal approach to the treatment of CBD stones in younger and fit patients. The choice between ES alone and laparoscopic-ES rendezvous in older or high-risk patients remains uncertain.</p>","PeriodicalId":46408,"journal":{"name":"Rambam Maimonides Medical Journal","volume":"15 2","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11065094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Current State of Knowledge on Osteoporosis in Holocaust Survivors and Their Descendants. 大屠杀幸存者及其后代骨质疏松症的知识现状。
IF 1.5
Rambam Maimonides Medical Journal Pub Date : 2024-04-28 DOI: 10.5041/RMMJ.10523
Malvina Hoxha, Visar Malaj
{"title":"The Current State of Knowledge on Osteoporosis in Holocaust Survivors and Their Descendants.","authors":"Malvina Hoxha, Visar Malaj","doi":"10.5041/RMMJ.10523","DOIUrl":"10.5041/RMMJ.10523","url":null,"abstract":"<p><strong>Objective: </strong>Starvation in early life can cause poor bone health and metabolic aberrations in bone minerals, leading to abnormal bone development. Holocaust survivors have been exposed to starvation and malnutrition before and during World War II. This paper aims to provide the current state of knowledge on the osteoporosis risk in Holocaust survivors and their descendants.</p><p><strong>Methods: </strong>The PubMed and Scopus databases were searched. Papers that reported original data on the risk of osteoporosis in Holocaust survivors and in their offspring were included in the study.</p><p><strong>Results: </strong>Ten studies were included in this review. The majority of studies were case-control ones (n=7) versus two self-reported and one longitudinal study. Despite the limited cohort numbers and the small number of studies in the literature, the data showed a potential increased risk of osteoporosis in Holocaust survivors and especially in their descendants.</p><p><strong>Conclusions: </strong>The review of these studies showed a higher prevalence of osteoporosis among Holocaust survivors and their offspring. Knowledge of the trans-generational inheritance of osteoporosis in the descendants of Holocaust survivors should increase the awareness of primary care health workers on osteoporosis screening and early diagnosis and implementation of preventive measures, including adequate vitamin D and calcium supplementation, and pharmacological treatment.</p>","PeriodicalId":46408,"journal":{"name":"Rambam Maimonides Medical Journal","volume":"15 2","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11065091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coronary Artery Surgery: Past, Present, and Future. 冠状动脉手术:过去、现在和未来。
IF 1.5
Rambam Maimonides Medical Journal Pub Date : 2024-01-19 DOI: 10.5041/RMMJ.10515
Elizabeth C Ghandakly, Gabriele M Iacona, Faisal G Bakaeen
{"title":"Coronary Artery Surgery: Past, Present, and Future.","authors":"Elizabeth C Ghandakly, Gabriele M Iacona, Faisal G Bakaeen","doi":"10.5041/RMMJ.10515","DOIUrl":"10.5041/RMMJ.10515","url":null,"abstract":"<p><p>Coronary artery bypass grafting (CABG) is the most commonly performed and studied major cardiac operation worldwide. An understanding of the evolution of CABG, including the early days of cardiac surgery, the first bypass operation, continuous improvements in techniques, and streamlining of the operation, is important to inform current trends and future innovations. This article will examine how CABG evolved (from techniques to conduits), describe current trends in the field, and explore what lies on the horizon for the future of CABG.</p>","PeriodicalId":46408,"journal":{"name":"Rambam Maimonides Medical Journal","volume":"15 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10807854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Familial Occurrence of Isolated Late-onset Nasolacrimal Duct Obstruction in Two Unrelated Families. 在两个无血缘关系的家族中出现孤立的晚发性鼻泪管阻塞。
IF 1.5
Rambam Maimonides Medical Journal Pub Date : 2024-01-19 DOI: 10.5041/RMMJ.10519
Anat Bahat Dinur, Ortal Buchbut, Libe Gradstein, Baker Elsana, Ofek Freund, Ohad S Birk, Erez Tsumi
{"title":"Familial Occurrence of Isolated Late-onset Nasolacrimal Duct Obstruction in Two Unrelated Families.","authors":"Anat Bahat Dinur, Ortal Buchbut, Libe Gradstein, Baker Elsana, Ofek Freund, Ohad S Birk, Erez Tsumi","doi":"10.5041/RMMJ.10519","DOIUrl":"10.5041/RMMJ.10519","url":null,"abstract":"<p><p>Late-onset nasolacrimal duct obstruction (NLDO) as a result of inflammatory processes causing dacryo-stenosis is a common entity affecting mostly women. While a few mechanisms have been suggested as contributors to the expression of NLDO, the trigger for the inflammation remains mostly unknown. Familial predilection for this condition has not been previously reported. We present two families with multiple individuals affected with congenital or late-onset NLDO, describe the signs and symptoms of the affected individuals, and explore their medical history for any contributing factors. Family A, spanning four generations, included 7 female patients affected by late-onset NLDO. Family B, spanning two generations, included 8 individuals affected by either congenital or late-onset NLDO. This case series suggests a familial predisposition to NLDO, apparently with an autosomal dominant inheritance pattern. Further studies are needed to elucidate the molecular basis of this genetic predisposition.</p>","PeriodicalId":46408,"journal":{"name":"Rambam Maimonides Medical Journal","volume":"15 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10807852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgery for Cardiac Arrhythmias: Past, Present, Future. 心律失常手术:过去、现在和未来。
IF 1.5
Rambam Maimonides Medical Journal Pub Date : 2024-01-19 DOI: 10.5041/RMMJ.10516
Stephen D Waterford, Niv Ad
{"title":"Surgery for Cardiac Arrhythmias: Past, Present, Future.","authors":"Stephen D Waterford, Niv Ad","doi":"10.5041/RMMJ.10516","DOIUrl":"10.5041/RMMJ.10516","url":null,"abstract":"<p><p>There is a rich history of surgery for cardiac arrhythmias, spanning from atrial fibrillation and Wolff-Parkinson-White syndrome to inappropriate sinus tachycardia and ventricular tachycardia. This review describes the history of these operations, their evolution over time, and the current state of practice. We devote considerable time to the discussion of atrial fibrillation, the most common cardiac arrhythmia addressed by surgeons. We discuss ablation of atrial fibrillation as a stand-alone operation and as a concomitant operation performed at the time of cardiac surgery. We also discuss the emergence of newer procedures to address atrial fibrillation in the past decade, such as the convergent procedure and totally thoracoscopic ablation, and their outcomes relative to historic approaches such as the Cox maze procedure.</p>","PeriodicalId":46408,"journal":{"name":"Rambam Maimonides Medical Journal","volume":"15 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10807855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimally Invasive Pectus Excavatum Correction and Endoscopic Port Access Mitral Valve Surgery. 微创胸大肌矫正术和内窥镜入孔二尖瓣手术。
IF 1.5
Rambam Maimonides Medical Journal Pub Date : 2024-01-19 DOI: 10.5041/RMMJ.10517
Johan van der Merwe, Filip Casselman, Ivan Degrieck, Frank Van Praet
{"title":"Minimally Invasive Pectus Excavatum Correction and Endoscopic Port Access Mitral Valve Surgery.","authors":"Johan van der Merwe, Filip Casselman, Ivan Degrieck, Frank Van Praet","doi":"10.5041/RMMJ.10517","DOIUrl":"10.5041/RMMJ.10517","url":null,"abstract":"<p><p>This case study describes the successful short-term outcome of staged minimally invasive pectus excavatum correction and endoscopic mitral valve repair in a patient with severe mitral valve regurgitation and pectus excavatum.</p>","PeriodicalId":46408,"journal":{"name":"Rambam Maimonides Medical Journal","volume":"15 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10807853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Against Over-reliance on PRISMA Guidelines for Meta-analytical Studies. 反对过度依赖《元分析研究 PRISMA 指南》。
IF 1.5
Rambam Maimonides Medical Journal Pub Date : 2024-01-19 DOI: 10.5041/RMMJ.10518
Jaime A Teixeira da Silva, Timothy Daly
{"title":"Against Over-reliance on PRISMA Guidelines for Meta-analytical Studies.","authors":"Jaime A Teixeira da Silva, Timothy Daly","doi":"10.5041/RMMJ.10518","DOIUrl":"10.5041/RMMJ.10518","url":null,"abstract":"<p><p>The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were elaborated to allow authors of such papers to identify quality articles for inclusion in their scholarly work. However, we have identified several issues that point to an over-reliance on the PRISMA guidelines. Firstly, we question the rigor of implementation by authors and the rigor of verification by peer reviewers and editors, and whether they have screened papers to ensure adherence to the PRISMA guidelines. Secondly, we have identified cases where the PRISMA criteria led to as much as 99.97% of the published literature being ignored, suggesting that valid publications meeting these criteria might be at risk of being ignored. Thirdly, we have noted that exclusion is not only a quantitative problem-it is also a qualitative one, since the screening procedure groups all non-conforming literature into one basket. Fourthly, we have noted that seven copies of the PRISMA guidelines exist. This being the case, which one should be cited? To replace over-reliance on PRISMA screening, we encourage authors, peer reviewers, and editors to publish systematic reviews and meta-analyses that respect the dual criteria of scientific plausibility and diversity of included papers.</p>","PeriodicalId":46408,"journal":{"name":"Rambam Maimonides Medical Journal","volume":"15 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10807856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Action Myoclonus Secondary to Donepezil: Case Report and Literature Review. 多奈哌齐继发动作性肌阵挛:病例报告和文献复习。
IF 1.5
Rambam Maimonides Medical Journal Pub Date : 2023-10-29 DOI: 10.5041/RMMJ.10510
Jamir Pitton Rissardo, Ana Letícia Fornari Caprara
{"title":"Action Myoclonus Secondary to Donepezil: Case Report and Literature Review.","authors":"Jamir Pitton Rissardo,&nbsp;Ana Letícia Fornari Caprara","doi":"10.5041/RMMJ.10510","DOIUrl":"10.5041/RMMJ.10510","url":null,"abstract":"<p><p>Movement disorders associated with donepezil have been only rarely reported. Herein, we describe an older woman who developed myoclonus secondary to donepezil. A 61-year-old female presented with brief involuntary twitching. The patient reported that she consulted a general practitioner about 1 month before due to memory complaints. A diagnosis of mild cognitive impairment was made. Donepezil was started. After 4 weeks, she presented to our emergency department due to significant twitching. Multifocal myoclonus was observed. These movements occurred during rest and voluntary movement. Laboratory exams and cerebrospinal fluid analysis were normal. A cranial computed tomography and brain magnetic resonance imaging were unremarkable. Electroencephalography did not show epileptic activity. Electromyography revealed burst durations varying between 50 and 100 ms. Diazepam intravenous was started, which improved her abnormal movement within 1 hour. On the next day, she developed the same clinical symptoms of presentation. Donepezil was discontinued, and clonazepam was started. The patient had a complete recovery from her myoclonus. To the authors' knowledge, there are six reports of myoclonus secondary to donepezil/galantamine. There is no report of rivastigmine-induced myoclonus. The most frequent presentation was multifocal myoclonus. The management was the discontinuation of the acetylcholinesterase inhibitor. All the individuals recovered within 3 weeks.</p>","PeriodicalId":46408,"journal":{"name":"Rambam Maimonides Medical Journal","volume":"14 4","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Release Our Hostages Now! 立即释放我们的人质!
IF 1.5
Rambam Maimonides Medical Journal Pub Date : 2023-10-29 DOI: 10.5041/RMMJ.10507
Itamar Ashkenazi, Rafael Beyar, Shraga Blazer, Aaron Ciechanover, Karl L Skorecki
{"title":"Release Our Hostages Now!","authors":"Itamar Ashkenazi,&nbsp;Rafael Beyar,&nbsp;Shraga Blazer,&nbsp;Aaron Ciechanover,&nbsp;Karl L Skorecki","doi":"10.5041/RMMJ.10507","DOIUrl":"10.5041/RMMJ.10507","url":null,"abstract":"","PeriodicalId":46408,"journal":{"name":"Rambam Maimonides Medical Journal","volume":"14 4","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cannabis and Rheumatoid Arthritis: A Scoping Review Evaluating the Benefits, Risks, and Future Research Directions. 大麻和类风湿性关节炎:评估益处、风险和未来研究方向的范围综述。
IF 1.4
Rambam Maimonides Medical Journal Pub Date : 2023-10-29 DOI: 10.5041/RMMJ.10509
Nicole Paland, Haya Hamza, Antonina Pechkovsky, Miran Aswad, Dayana Shagidov, Igal Louria-Hayon
{"title":"Cannabis and Rheumatoid Arthritis: A Scoping Review Evaluating the Benefits, Risks, and Future Research Directions.","authors":"Nicole Paland, Haya Hamza, Antonina Pechkovsky, Miran Aswad, Dayana Shagidov, Igal Louria-Hayon","doi":"10.5041/RMMJ.10509","DOIUrl":"10.5041/RMMJ.10509","url":null,"abstract":"<p><p>Rheumatoid diseases, including rheumatoid arthritis, osteoarthritis, and fibromyalgia, are characterized by progressive inflammation in the musculoskeletal system, predominantly affecting the joints and leading to cartilage and bone damage. The resulting pain and ongoing degradation of the musculoskeletal system contribute to reduced physical activity, ultimately impacting quality of life and imposing a substantial socioeconomic burden. Unfortunately, current therapeutics have limited efficacy in slowing disease progression and managing pain. Thus, the development of novel and alternative therapies is imperative. Cannabinoids possess beneficial properties as potential treatments for rheumatoid diseases due to their anti-inflammatory and analgesic properties. Preclinical studies have demonstrated promising results in halting disease progression and relieving pain. However, there is a scarcity of patient clinical studies, and the available data show mixed results. Consequently, there are currently no established clinical recommendations regarding the utilization of cannabis for treating rheumatoid diseases. In this review, we aim to explore the concept of cannabis use for rheumatoid diseases, including potential adverse effects. We will provide an overview of the data obtained from preclinical and clinical trials and from retrospective studies on the efficacy and safety of cannabis in the treatment of rheumatoid diseases.</p>","PeriodicalId":46408,"journal":{"name":"Rambam Maimonides Medical Journal","volume":"14 4","pages":""},"PeriodicalIF":1.4,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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