B Amro, M Ramirez, R Farhan, M Abdulrahim, Z Hakim, S Alsuwaidi, E Alzahmi, M Tahlak, P R Koninckx, A Wattiez
{"title":"Isthmoceles - Accuracy of imaging diagnosis and clinical correlation with histology: A prospective cohort study.","authors":"B Amro, M Ramirez, R Farhan, M Abdulrahim, Z Hakim, S Alsuwaidi, E Alzahmi, M Tahlak, P R Koninckx, A Wattiez","doi":"10.52054/FVVO.16.2.021","DOIUrl":"10.52054/FVVO.16.2.021","url":null,"abstract":"<p><strong>Background: </strong>Isthmoceles are a growing clinical concern.</p><p><strong>Objectives: </strong>To evaluate the accuracy of diagnosis of isthmoceles by imaging and to correlate the dimensions with clinical symptoms and histopathology.</p><p><strong>Materials and methods: </strong>Prospective study of women (n=60) with ≥1 C-section undergoing hysterectomy. Isthmoceles were measured by imaging before surgery and macroscopically on the specimen after hysterectomy, followed by histological analysis.</p><p><strong>Main outcome measures: </strong>Accuracy of isthmocele diagnosis, correlation with clinical symptoms, and histopathological findings.</p><p><strong>Result: </strong>By imaging, isthmoceles were slightly deeper (P=0.0176) and shorter (P=0.0045) than macroscopic measurements. Differences were typically small (≤3mm). Defined as an indentation of ≥2 mm at site of C-section scar, imaging diagnosed 2 isthmoceles consequently not seen by histology and missed 3. Number of prior C-sections increased isthmocele severity but neither the incidence nor the remaining myometrial thickness (RMT) did. Severity correlated positively with symptoms and histology. However, clinical use was limited. Histological analysis revealed presence of thick wall vessels in 100%, elastosis in 40%, and adenomyosis in 38%. Isthmocele lining was asynchronous with the menstrual phase in 31%.</p><p><strong>Conclusions: </strong>Dimensions of isthmoceles by imaging were largely accurate with occasionally large differences observed. Number of C-sections did not increase isthmocele incidence, only severity. Indication for surgery remains clinical, considering dimensions and symptoms.</p><p><strong>What is new?: </strong>Dimensions of isthmoceles should be confirmed before surgery since uterine contractions might change those dimensions. Symptoms increase with dimensions of isthmoceles but are not specific. Endometrial lining within the isthmocele can be asynchronous with the menstrual phase.</p>","PeriodicalId":46400,"journal":{"name":"Facts Views and Vision in ObGyn","volume":"16 2","pages":"173-183"},"PeriodicalIF":1.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Pavone, N Bizzarri, M Goglia, L Lecointre, A Fagotti, G Scambia, D Querleu, C Akladios
{"title":"Laparoscopic transabdominal cerclage in a pregnant woman after fertility-sparing treatment for early-stage cervical cancer: an operative technique in ten steps.","authors":"M Pavone, N Bizzarri, M Goglia, L Lecointre, A Fagotti, G Scambia, D Querleu, C Akladios","doi":"10.52054/FVVO.16.2.018","DOIUrl":"10.52054/FVVO.16.2.018","url":null,"abstract":"<p><strong>Introduction: </strong>Fertility-sparing treatments are increasingly used in patients with early-stage cervical cancer. The residual shortened cervix might increase the risk of preterm birth. When a vaginal cerclage is not technically feasible, a laparoscopic transabdominal cerclage (LAC) could be offered before or after conception. In this article, we show how to safely perform a post-conceptional LAC in patients with insufficient residual cervical length for vaginal cerclage.</p><p><strong>Methods: </strong>A 34-year-old patient in the twelfth week of gestation who previously underwent repeated conisation for cervical cancer FIGO stage IA1 in 2021 was referred for cervical stenosis, which required a subsequent vaginal tracheoplasty. She became pregnant 3 months later. Ultrasound monitoring of the cervix showed a 15 mm cervical length. A step-by-step LAC in a pregnant woman was performed. Results: The Doppler velocimetry of the uterine arteries at the end of the procedure was normal. No intraoperative or postoperative complications were reported. The estimated blood loss was 100 mL and the total operative time of 120 min. The patient was discharged on the third postoperative day. A caesarean section was performed at 36 weeks of gestation for spontaneous contractions with excellent obstetric (male, 2860 gr) and neonatal outcomes.</p><p><strong>Conclusion: </strong>LAC in pregnancy, although made more difficult due to the size of the uterus, is a safe and feasible procedure combining the advantages of minimally invasive surgery with excellent obstetric result.</p><p><strong>Learning objective: </strong>In this video is shown how to perform a post-conceptional transabdominal laparoscopic cerclage in a young woman with no sufficient cervical length for a vaginal approach.</p>","PeriodicalId":46400,"journal":{"name":"Facts Views and Vision in ObGyn","volume":"16 2","pages":"217-223"},"PeriodicalIF":1.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transvaginal ultrasound reliably detects and classifies most cases of deep endometriosis.","authors":"A Forman","doi":"10.52054/FVVO.16.2.019","DOIUrl":"https://doi.org/10.52054/FVVO.16.2.019","url":null,"abstract":"","PeriodicalId":46400,"journal":{"name":"Facts Views and Vision in ObGyn","volume":"16 2","pages":"125-126"},"PeriodicalIF":1.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Vallée, E Saridogan, F Petraglia, J Keckstein, N Polyzos, C Wyns, L Gianaroli, B Tarlatzis, J M Ayoubi, A Feki
{"title":"Horizons in Endometriosis: Proceedings of the Montreux Reproductive Summit, 14-15 July 2023.","authors":"A Vallée, E Saridogan, F Petraglia, J Keckstein, N Polyzos, C Wyns, L Gianaroli, B Tarlatzis, J M Ayoubi, A Feki","doi":"10.52054/FVVO.16.s1.011","DOIUrl":"10.52054/FVVO.16.s1.011","url":null,"abstract":"<p><p>Endometriosis is a complex and chronic gynaecological disorder that affects millions of women worldwide, leading to significant morbidity and impacting reproductive health. This condition affects up to 10% of women of reproductive age and is characterised by the presence of endometrial-like tissue outside the uterus, potentially leading to symptoms such as chronic pelvic pain, dysmenorrhoea, dyspareunia, and infertility. The Montreux summit brought a number of experts in this field together to provide a platform for discussion and exchange of ideas. These proceedings summarise the six main topics that were discussed at this summit to shed light on future directions of endometriosis classification, diagnosis, and therapeutical management. The first question addressed the possibility of preventing endometriosis in the future by identifying risk factors, genetic predispositions, and further understanding of the pathophysiology of the condition to develop targeted interventions. The clinical presentation of endometriosis is varied, and the correlation between symptoms severity and disease extent is unclear. While there is currently no universally accepted optimal classification system for endometriosis, several attempts striving towards its optimisation - each with its own advantages and limitations - were discussed. The ideal classification should be able to reconcile disease status based on the various diagnostic tools, and prognosis to guide proper patient tailored management. Regarding diagnosis, we focused on future tools and critically discussed emerging approaches aimed at reducing diagnostic delay. Preserving fertility in endometriosis patients was another debatable aspect of management that was reviewed. Moreover, besides current treatment modalities, potential novel medical therapies that can target underlying mechanisms, provide effective symptom relief, and minimise side effects in endometriotic patients were considered, including hormonal therapies, immunomodulation, and regenerative medicine. Finally, the question of hormonal substitution therapy after radical treatment for endometriosis was debated, weighing the benefits of hormone replacement.</p>","PeriodicalId":46400,"journal":{"name":"Facts Views and Vision in ObGyn","volume":"16 16 Suppl 1","pages":"1-32"},"PeriodicalIF":1.7,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11317919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The glass ceiling of endometriosis surgeons is research.","authors":"P R Koninckx, A Ussia, S W Guo, E Saridogan","doi":"10.52054/FVVO.16.1.011","DOIUrl":"10.52054/FVVO.16.1.011","url":null,"abstract":"","PeriodicalId":46400,"journal":{"name":"Facts Views and Vision in ObGyn","volume":"16 1","pages":"1-3"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11198886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of minimally invasive surgery in gynaecological cancer: an overview of current trends.","authors":"D Balafoutas, N Vlahos","doi":"10.52054/FVVO.16.1.005","DOIUrl":"10.52054/FVVO.16.1.005","url":null,"abstract":"<p><strong>Background: </strong>The capabilities of minimally invasive surgery, either as conventional laparoscopy, or as robotic surgery, have increased to an extent that it enables complex operations in the field of gynaecological oncology.</p><p><strong>Objective: </strong>To document the role of minimally invasive gynaecological surgery in cancer.</p><p><strong>Materials and methods: </strong>A review of the literature that shaped international guidelines and clinical practice.</p><p><strong>Main outcome measures: </strong>Current guidelines of major international scientific associations and trends in accepted clinical practice.</p><p><strong>Results: </strong>In recent years, evidence on oncologic outcome has limited the role of minimally invasive techniques in cervical cancer, while the treatment of early endometrial cancer with laparoscopy and robotic surgery has become the international standard. In ovarian cancer, the role of minimally invasive surgery is still limited. Current evidence on perioperative morbidity underlines the necessity to implicate minimally invasive techniques whenever possible.</p><p><strong>Conclusion: </strong>The optimal surgical route for the treatment of gynaecological cancer remains in many cases controversial. The role of minimally invasive surgery remains increasing in the course of time.</p><p><strong>What is new?: </strong>This comprehensive review offers an entire perspective on the current role of minimally invasive surgery in gynaecological cancer therapy.</p>","PeriodicalId":46400,"journal":{"name":"Facts Views and Vision in ObGyn","volume":"16 1","pages":"23-33"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11198884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Caballero Campo, F Pérez Milán, M Carrera Roig, E Moratalla Bartolomé, J A Domínguez Arroyo, J L Alcázar Zambrano, L Alonso Pacheco, J Carugno
{"title":"Impact of congenital uterine anomalies on obstetric and perinatal outcomes: systematic review and meta-analysis.","authors":"M Caballero Campo, F Pérez Milán, M Carrera Roig, E Moratalla Bartolomé, J A Domínguez Arroyo, J L Alcázar Zambrano, L Alonso Pacheco, J Carugno","doi":"10.52054/FVVO.16.1.004","DOIUrl":"10.52054/FVVO.16.1.004","url":null,"abstract":"<p><strong>Background: </strong>Congenital uterine anomalies (CUA) can be associated with impairments of early and late pregnancy events.</p><p><strong>Objective: </strong>To assess the impact of CUA on reproductive outcomes in pregnancies conceived spontaneously or after assisted reproduction.</p><p><strong>Materials and methods: </strong>Systematic review and meta-analysis of cohort studies comparing patients with CUA versus women with normal uterus. A structured literature search was performed in leading scientific databases to identify prospective and retrospective studies. The Newcastle-Ottawa scale, adapted to AHRQ standards, was used to assess the risk of bias. Pooled odds ratios (OR) were calculated. Publication bias and statistical heterogeneity were assessed, and meta-regression was used to analyse the heterogeneity.</p><p><strong>Main outcome measures: </strong>Miscarriage, ectopic pregnancy, placental abruption, term, and premature rupture of membranes (PROM), malpresentation at delivery, preterm delivery prior to 37, 34 and 32 weeks, caesarean delivery, intrauterine growth restriction/small for gestational age, foetal mortality and perinatal mortality.</p><p><strong>Results: </strong>32 studies were included. CUAs increased significantly the risk of first/second trimester miscarriage (OR:1.54;95%CI:1.14-2.07), placental abruption (OR:5.04;3.60-7.04), PROM (OR:1.71;1.34-2.18), foetal malpresentation at delivery (OR:21.04;10.95-40.44), preterm birth (adjusted OR:4.34;3.59-5.21), a caesarean delivery (adjusted OR:7.69;4.17-14.29), intrauterine growth restriction/small for gestational age (adjusted OR:50;6.11-424), foetal mortality (OR:2.07;1.56-2.73) and perinatal mortality (OR:3.28;2.01-5.36).</p><p><strong>Conclusions: </strong>CUA increases the risk of complications during pregnancy, delivery, and postpartum. Complications most frequent in CUA patients were preterm delivery, foetal malpresentation, and caesarean delivery.</p><p><strong>What is new?: </strong>Bicornuate uterus was associated with the highest number of adverse outcomes, followed by didelphys, subseptate and septate uterus.</p>","PeriodicalId":46400,"journal":{"name":"Facts Views and Vision in ObGyn","volume":"16 1","pages":"9-22"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11198883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S M Strong, A A McDougall, A M Abdelmohsen, A Maku, A Dehnel, R Mallick, F Odejinmi
{"title":"Current opinion on large-scale prospective myomectomy databases toward evidence-based preconception and antenatal counselling utilising a standardised myomectomy operation note.","authors":"S M Strong, A A McDougall, A M Abdelmohsen, A Maku, A Dehnel, R Mallick, F Odejinmi","doi":"10.52054/FVVO.16.4.006","DOIUrl":"10.52054/FVVO.16.4.006","url":null,"abstract":"<p><strong>Background: </strong>No large-scale databases exist of pregnancy outcomes and rate of uterine rupture for women after myomectomy, resulting in inconsistent antenatal counselling and decision-making regarding mode and timing of delivery. Standardising information collected at myomectomy may facilitate data collection, informing prenatal/ antenatal counselling.</p><p><strong>Objectives: </strong>To determine clinician opinions regarding standardisation of myomectomy operation notes to allow comprehensive data input into a prospective database of pregnancy outcomes, toward an evidence-based approach to decision making regarding timing and mode of delivery in subsequent pregnancies.</p><p><strong>Materials and methods: </strong>A google forms survey was emailed to all consultant (attending-level) obstetricians and gynaecologists across 25 hospitals in London, Kent, Surrey, and Sussex (UK) between March and May 2022. To enhance response rates, two further email reminders were sent alongside in-person reminders from selected local unit representatives.</p><p><strong>Main outcome measures: </strong>Senior clinician opinion for characteristics necessary to collect at time of surgery to develop a widescale database of post myomectomy pregnancy outcomes.</p><p><strong>Results: </strong>209/475 (44%) responses received; 95% (198/209) agreed with standardising operation notes. Criteria selected for inclusion included cavity breach (98%, 194/198), location (98%, 194/198), number of fibroids removed (93%, 185/198) and number of uterine incisions (96%, 190/198).</p><p><strong>Conclusions: </strong>Gynaecologists support standardising myomectomy operation notes to inform the development of prospective large-scale databases of pregnancy outcomes after myomectomy.</p><p><strong>What is new?: </strong>Acquisition of clinician opinions on the development and content of a standardised myomectomy operation note to aid the development of a pregnancy-outcome database for women after myomectomy.</p>","PeriodicalId":46400,"journal":{"name":"Facts Views and Vision in ObGyn","volume":"16 1","pages":"59-65"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11198879/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
X Zheng, X Yu, X Xie, G Lyu, J Niu, X Li, H Chen, A Watrelot, J Guan
{"title":"The Clinical Significance of Subtle Distal Fallopian Tube Abnormalities: A Multicentre Prospective Observational Study.","authors":"X Zheng, X Yu, X Xie, G Lyu, J Niu, X Li, H Chen, A Watrelot, J Guan","doi":"10.52054/FVVO.16.1.007","DOIUrl":"10.52054/FVVO.16.1.007","url":null,"abstract":"<p><strong>Background: </strong>Subtle distal fallopian tube abnormalities are a group of diseases characterised by small variations in tubal anatomy. The clinical significance of these abnormalities need to be studied.</p><p><strong>Objectives: </strong>The purpose of this multicentre prospective observational study was to investigate whether subtle distal fallopian tube abnormalities are related to infertility and endometriosis.</p><p><strong>Materials and methods: </strong>The investigation was carried out in five medical centres in China and France from February to July 2021 and included reproductive-age patients who underwent gynaecological laparoscopy. Subtle abnormalities included Hydatid of Morgagni (HM) , fimbrial agglutination, tubal diverticula, accessory ostium, fimbrial phimosis, and accessory fallopian tube.</p><p><strong>Results: </strong>642 patients were enrolled in the study and 257 (40.0%) were diagnosed with subtle tube abnormalities. Hydatid of Morgagni was the most common abnormality (22.7%; n=146), followed by fimbrial agglutination (19.8%; n=127), tubal diverticula (6.9%; n=44), accessory tube (2.0%; n=13), and tubal accessory ostium (1.9%; n=12). Fimbrial phimosis was the least common abnormality (0.3%; n=2). The prevalence of subtle fallopian tube abnormalities was significantly higher among infertile patients (188/375, 50.1%) than those without history of infertility (69/267, 25.8%, ᶍ2=38.332, P=0.000). 209 patients were diagnosed with endometriosis during surgery, and the prevalence of subtle abnormalities was significantly higher in the endometriosis group than in those without endometriosis (61.2%, [128/209] vs. 29.8% [129/433], ᶍ2=58.086, P=0.000).</p><p><strong>Conclusions: </strong>Higher prevalence of subtle tubal abnormalities suggests that they may contribute to infertility. They are highly related to endometriosis and indicate fimbrial abnormalities of endometriosis.</p><p><strong>What is new?: </strong>This is the largest multicentre study to investigate the subtle distal fallopian tube abnormalities in infertile women. Compared to previous studies, this study includes the main subtle distal abnormalities and the control group patients without a history of infertility.</p>","PeriodicalId":46400,"journal":{"name":"Facts Views and Vision in ObGyn","volume":"16 1","pages":"67-73"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11198887/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Russo, L Lazzeri, T Siciliano, A Selntigia, D Farsetti, C Chiaramonte, F G Martire, E Zupi, C Exacoustos
{"title":"Reproducibility of #Enzian classification by transvaginal ultrasound and its correlation with symptoms.","authors":"C Russo, L Lazzeri, T Siciliano, A Selntigia, D Farsetti, C Chiaramonte, F G Martire, E Zupi, C Exacoustos","doi":"10.52054/FVVO.16.1.008","DOIUrl":"10.52054/FVVO.16.1.008","url":null,"abstract":"<p><strong>Background: </strong>The #Enzian classification represents a system to describe endometriotic lesions during surgery. Its use is well established in correlating ultrasound and surgical findings.</p><p><strong>Objectives: </strong>To describe interobserver reproducibility of ultrasound use and symptom correlation with compartments involved using #Enzian classification.</p><p><strong>Materials and methods: </strong>Two experienced operators performed transvaginal sonography (TVS) in 52 patients affected by pelvic endometriosis. A rate agreement was determined. A further 200 women with endometriotic TVS signs, with no previous surgery and not taking any hormonal therapy, were staged by one of three different operators according to the #Enzian (compartments A, B, C, O, T, FA, FB, FI, FU, FO). Statistical analysis compared all the compartments, as single or associated, with single or combined symptoms (dysmenorrhea, dyspareunia, heavy menstrual bleeding - HMB, bowel symptoms).</p><p><strong>Main outcome measures: </strong>Evaluation of the reproducibility of #Enzian classification in assessing pelvic endometriosis among different operators using TVS, and of possible associations between symptoms and specific #Enzian compartments.</p><p><strong>Results: </strong>Excellent agreement between the two operators in evaluating almost all the compartments (k >0.8) was observed. Dysmenorrhea did not correlate with any specific compartment. We observed a significant association between dyspareunia and B compartment (p=0.02). HMB is associated with FA (p=0.02). Bowel symptoms were associated with B (p=0.02). Combining more symptoms, we observed more significant associations with different compartments.</p><p><strong>Conclusions: </strong>#ENZIAN classification is reproducible in the evaluation of pelvic endometriosis. Some symptoms are correlated to specific ultrasound signs of the disease.</p><p><strong>What is new?: </strong>An accurate evaluation of symptoms could guide TVS examination to detect specific endometriotic lesions and establish the best management for the patients.</p>","PeriodicalId":46400,"journal":{"name":"Facts Views and Vision in ObGyn","volume":"16 1","pages":"47-58"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11198882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}