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Burden and Determinants of Anemia in a Rural Population in South India: A Cross-Sectional Study. 印度南部农村人口贫血的负担和决定因素:一项横断面研究。
IF 2.9
Anemia Pub Date : 2018-07-15 eCollection Date: 2018-01-01 DOI: 10.1155/2018/7123976
Matthew Little, Chloe Zivot, Sally Humphries, Warren Dodd, Kirit Patel, Cate Dewey
{"title":"Burden and Determinants of Anemia in a Rural Population in South India: A Cross-Sectional Study.","authors":"Matthew Little,&nbsp;Chloe Zivot,&nbsp;Sally Humphries,&nbsp;Warren Dodd,&nbsp;Kirit Patel,&nbsp;Cate Dewey","doi":"10.1155/2018/7123976","DOIUrl":"https://doi.org/10.1155/2018/7123976","url":null,"abstract":"<p><strong>Background/objectives: </strong>To determine the prevalence and determinants of blood haemoglobin level and mild, moderate, and severe anemia in a sample of adults from rural Tamil Nadu, India.</p><p><strong>Subjects/methods: </strong>We recruited a sample of men and nonpregnant women aged 20 years and older. Clinical health measures included blood haemoglobin concentration and body mass index. We assessed associations between anemia outcomes and sociodemographic and dietary factors using linear and logistic regression modeling.</p><p><strong>Results: </strong>A total of 753 individuals (412 women and 341 men) participated in this study. The prevalence of anemia was 57.2% among women and 39.3% among men (<i>P</i><0.001). Prevalence of anemia increased with age among men (<i>P</i><0.001) but not women (<i>P</i>>0.05). Iron intake was low; 11.7% women and 24.1% of men reported iron intakes above recommended dietary allowances (<i>P</i><0.001). Factors (OR (95% CI)) associated with mild or moderate anemia among women included television ownership (0.27 (0.13, 0.58)), livestock ownership (0.46 (0.28, 0.75)), refined grain consumption (1.32 (1.02, 1.72)), meat consumption (0.84 (0.71, 0.99)), and commercial agriculture production (mild: 4.6 (1.1, 18.8); moderate: 6.8 (1.98, 23.1)). Factors associated with mild, moderate, or severe anemia among men included rurality (0.50 (0.25, 0.99)), sugar consumption (1.04 (1.01, 1.06)), egg consumption (0.80 (0.65, 0.99)), and high caste (7.3 (1.02, 52.3)).</p><p><strong>Conclusion: </strong>Both women and men in this region may be particularly vulnerable to anemia, and future research must expand beyond dietary risk factors to examine the impacts of sociodemographic and environmental factors.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2018 ","pages":"7123976"},"PeriodicalIF":2.9,"publicationDate":"2018-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/7123976","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36402424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Multilevel Analysis of Determinants of Anemia Prevalence among Children Aged 6-59 Months in Ethiopia: Classical and Bayesian Approaches. 埃塞俄比亚6-59个月儿童贫血患病率决定因素的多水平分析:经典和贝叶斯方法。
IF 2.9
Anemia Pub Date : 2018-06-03 eCollection Date: 2018-01-01 DOI: 10.1155/2018/3087354
Kemal N Kawo, Zeytu G Asfaw, Negusse Yohannes
{"title":"Multilevel Analysis of Determinants of Anemia Prevalence among Children Aged 6-59 Months in Ethiopia: Classical and Bayesian Approaches.","authors":"Kemal N Kawo,&nbsp;Zeytu G Asfaw,&nbsp;Negusse Yohannes","doi":"10.1155/2018/3087354","DOIUrl":"https://doi.org/10.1155/2018/3087354","url":null,"abstract":"<p><strong>Background: </strong>Anemia is a widely spread public health problem and affects individuals at all levels. However, there is a considerable regional variation in its distribution.</p><p><strong>Objective: </strong>Thus, this study aimed to assess and model the determinants of prevalence of anemia among children aged 6-59 months in Ethiopia.</p><p><strong>Data: </strong>Cross-sectional data from Ethiopian Demographic and Health Survey was used for the analysis. It was implemented by the Central Statistical Agency from 27 December 2010 through June 2011 and the sampling technique employed was multistage.</p><p><strong>Method: </strong>The statistical models that suit the hierarchical data such as variance components model, random intercept model, and random coefficients model were used to analyze the data. Likelihood and Bayesian approaches were used to estimate both fixed effects and random effects in multilevel analysis.</p><p><strong>Result: </strong>This study revealed that the prevalence of anemia among children aged between 6 and 59 months in the country was around 42.8%. The multilevel binary logistic regression analysis was performed to investigate the variation of predictor variables of the prevalence of anemia among children aged between 6 and 59 months. Accordingly, it has been identified that the number of children under five in the household, wealth index, age of children, mothers' current working status, education level, given iron pills, size of child at birth, and source of drinking water have a significant effect on prevalence of anemia. It is found that variances related to the random term were statistically significant implying that there is variation in prevalence of anemia across regions. From the methodological aspect, it was found that random intercept model is better compared to the other two models in fitting the data well. Bayesian analysis gave consistent estimates with the respective multilevel models and additional solutions as posterior distribution of the parameters.</p><p><strong>Conclusion: </strong>The current study confirmed that prevalence of anemia among children aged 6-59 months in Ethiopia was severe public health problem, where 42.8% of them are anemic. Thus, stakeholders should pay attention to all significant factors mentioned in the analysis of this study but wealth index/improving household income and availability of pure drinking water are the most influential factors that should be improved anyway.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2018 ","pages":"3087354"},"PeriodicalIF":2.9,"publicationDate":"2018-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/3087354","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36284869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 45
Association of Colecalciferol, Ferritin, and Anemia among Pregnant Women: Result from Cohort Study on Vitamin D Status and Its Impact during Pregnancy and Childhood in Indonesia. 孕妇中钙化醇、铁蛋白和贫血的关系:来自印度尼西亚孕期和儿童期维生素D状况及其影响的队列研究结果
IF 2.9
Anemia Pub Date : 2018-05-20 eCollection Date: 2018-01-01 DOI: 10.1155/2018/2047981
Raden Tina Dewi Judistiani, Lani Gumilang, Sefita Aryuti Nirmala, Setyorini Irianti, Deni Wirhana, Irman Permana, Liza Sofjan, Hesty Duhita, Lies Ani Tambunan, Jeffry Iman Gurnadi, Umar Seno, Reni Ghrahani, Agnes Rengga Indrati, Yunia Sribudiani, Tetty Yuniati, Budi Setiabudiawan
{"title":"Association of Colecalciferol, Ferritin, and Anemia among Pregnant Women: Result from Cohort Study on Vitamin D Status and Its Impact during Pregnancy and Childhood in Indonesia.","authors":"Raden Tina Dewi Judistiani, Lani Gumilang, Sefita Aryuti Nirmala, Setyorini Irianti, Deni Wirhana, Irman Permana, Liza Sofjan, Hesty Duhita, Lies Ani Tambunan, Jeffry Iman Gurnadi, Umar Seno, Reni Ghrahani, Agnes Rengga Indrati, Yunia Sribudiani, Tetty Yuniati, Budi Setiabudiawan","doi":"10.1155/2018/2047981","DOIUrl":"10.1155/2018/2047981","url":null,"abstract":"<p><p>Studies had shown that iron-cycling was disturbed by inflammatory process through the role of hepcidin. Pregnancy is characterized by shifts of interleukin. Our objective was to determine if 25(OH) vitamin D (colecalciferol) status was associated with ferritin, anemia, and its changes during pregnancy. <i>Method.</i> A cohort study was done in 4 cities in West Java, Indonesia, beginning in July 2016. Subjects were followed up until third trimester. Examinations included were maternal ferritin, colecalciferol, and haemoglobin level. <i>Result.</i> 191 (95.5%) subjects had low colecalciferol, and 151 (75.5%) among them were at deficient state. Anemia is found in 15 (7.5%) subjects, much lower than previous report. Proportion of anemia increased by trimester among women with colecalciferol deficiency. Ferritin status and prepregnancy body mass index in the first trimester were correlated with anemia (<i>r</i> = 0.147, <i>p</i> = 0.038 and <i>r</i> = -0.56, <i>p</i> = 0.03). Anemia in the second trimester was strongly correlated with anemia in the third trimester (<i>r</i> = 0.676, <i>p</i> < 0.01). <i>Conclusion.</i> Our study showed that the state of colecalciferol was not associated with either ferritin state or anemia, but proportion of anemia tends to increase by trimester in the colecalciferol deficient subjects.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2018 ","pages":"2047981"},"PeriodicalIF":2.9,"publicationDate":"2018-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/2047981","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36210485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Anaemia in Pregnancy: Prevalence, Risk Factors, and Adverse Perinatal Outcomes in Northern Tanzania. 妊娠贫血:在坦桑尼亚北部的流行,危险因素和不良围产期结局。
IF 2.9
Anemia Pub Date : 2018-05-02 eCollection Date: 2018-01-01 DOI: 10.1155/2018/1846280
Grace Stephen, Melina Mgongo, Tamara Hussein Hashim, Johnson Katanga, Babill Stray-Pedersen, Sia Emmanueli Msuya
{"title":"Anaemia in Pregnancy: Prevalence, Risk Factors, and Adverse Perinatal Outcomes in Northern Tanzania.","authors":"Grace Stephen,&nbsp;Melina Mgongo,&nbsp;Tamara Hussein Hashim,&nbsp;Johnson Katanga,&nbsp;Babill Stray-Pedersen,&nbsp;Sia Emmanueli Msuya","doi":"10.1155/2018/1846280","DOIUrl":"https://doi.org/10.1155/2018/1846280","url":null,"abstract":"<p><strong>Background and objective: </strong>Anaemia in pregnancy is a public health problem in developing countries. This study aimed to determine the prevalence, risk factors, and adverse perinatal outcomes of anaemia among pregnant women in Moshi Municipal, Northern Tanzania.</p><p><strong>Methods: </strong>This was a follow-up study conducted from October 2013 to June 2015. A total of 539 pregnant women were enrolled in this study. Interviews were conducted followed by determination of haemoglobin level. Women were followed up at delivery and at 7 days and 28 days after delivery.</p><p><strong>Results: </strong>A total of 529 women were included in this analysis. Their mean age was 25.8 (SD 5.73). The prevalence of anaemia was 18.0% and 2% had severe anaemia. The clinic of recruitment and low education level of the women were the factors that were independently associated with anaemia during pregnancy. At delivery, there were 10 stillbirths, 16 low birth weight (LBW) newborns, and 2 preterm birth cases. No association was found between anaemia and LBW, preterm birth, or stillbirths.</p><p><strong>Conclusion: </strong>Anaemia in pregnancy was a mild public health problem in the study setting of Northern Tanzania.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2018 ","pages":"1846280"},"PeriodicalIF":2.9,"publicationDate":"2018-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/1846280","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36182575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 181
Prevalence of Iron Deficiency Anemia among University Students in Hodeida Province, Yemen. 也门荷台达省大学生缺铁性贫血患病率
IF 2.9
Anemia Pub Date : 2018-04-23 eCollection Date: 2018-01-01 DOI: 10.1155/2018/4157876
Abdullah Ahmed Al-Alimi, Salem Bashanfer, Mohammed Abdo Morish
{"title":"Prevalence of Iron Deficiency Anemia among University Students in Hodeida Province, Yemen.","authors":"Abdullah Ahmed Al-Alimi,&nbsp;Salem Bashanfer,&nbsp;Mohammed Abdo Morish","doi":"10.1155/2018/4157876","DOIUrl":"https://doi.org/10.1155/2018/4157876","url":null,"abstract":"<p><strong>Background: </strong>Iron deficiency anemia (IDA) is one of the most common types of nutritional anemia in the worldwide and considered a major public health problem in developing countries especially in Yemen. Therefore, this cross-sectional study was conducted to determine the prevalence and risk factors of IDA among apparently healthy Yemeni students at Hodeida University.</p><p><strong>Method: </strong>Five hundred blood samples (326 males and 174 females) were collected randomly from medical students at Hodeida University. Participants were subjected to different tests including complete blood counts (CBC), serum ferritin (SF), serum iron (SI), and total iron binding capacity (TIBC). Moreover, a questionnaire was designed to collect demographics, food and drink habits, and socioeconomic status.</p><p><strong>Result: </strong>The overall prevalence of IDA was 30.4%  (<i>n</i> = 152), of whom 54.00% were females (<i>n</i> = 82) and 46.0% were males (<i>n</i> = 70). Students aged 20-22 years were found more anemic with prevalence 59.2% than students aged 17-19 years (25.0%) and 23-25 years (15.8%). Statistical analysis showed regularly having breakfast had significant (<i>p</i> < 0.001) role in preventing development of IDA compared with irregularly having breakfast. Infrequent consumption of vegetables/fruits; meat, fish, chicken; tea drinking; low household income; smoking and khat <i>(Catha edulis)</i> chewing showed a significant role (<i>p</i> < 0.001) in provoking of IDA, whereas consumption of coffee and cola showed insignificant influence (<i>p</i> = 0.585; <i>p</i> = 0.513) on IDA.</p><p><strong>Conclusion: </strong>This study revealed that the majority of university students, especially females, have IDA that might become worse by malnutrition, lifestyle habits, and lack of awareness. Our results suggest that IDA can be prevented by providing proper knowledge on the healthful diet, improved lifestyle, and harmful effect of IDA to the students.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2018 ","pages":"4157876"},"PeriodicalIF":2.9,"publicationDate":"2018-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/4157876","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36178619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 64
Frequency of Anemia and Iron Deficiency among Children Starting First Year of School Life and Their Association with Weight and Height. 入学一年级儿童贫血和缺铁的频率及其与体重和身高的关系
IF 2.9
Anemia Pub Date : 2018-04-10 eCollection Date: 2018-01-01 DOI: 10.1155/2018/8906258
Mirza Sultan Ahmad, Hadia Farooq, Sumaira Noor Maham, Zonaira Qayyum, Abdul Waheed, Waqar Nasir
{"title":"Frequency of Anemia and Iron Deficiency among Children Starting First Year of School Life and Their Association with Weight and Height.","authors":"Mirza Sultan Ahmad,&nbsp;Hadia Farooq,&nbsp;Sumaira Noor Maham,&nbsp;Zonaira Qayyum,&nbsp;Abdul Waheed,&nbsp;Waqar Nasir","doi":"10.1155/2018/8906258","DOIUrl":"https://doi.org/10.1155/2018/8906258","url":null,"abstract":"<p><p>The objectives of the study were to ascertain frequency of anemia and iron deficiency among children starting first year of school life and test association with height and weight. One in four children starting first year of school life in five schools of Rabwah, Pakistan, was included. Full blood counts and ferritin levels of the children included in the study were checked. Status of their height and weight was determined according to <i>Z</i>-score charts. Chi-square test was used to test association. Two hundred and ninety-five children with median age of 67 months were included in the study. Out of 295, 240 (81.4%) had normal Hb and 55 (18.6%) had anemia. Ferritin levels were found to be below normal level in 242 (82%) children. There was no significant difference between hemoglobin and ferritin levels of children belonging to different categories of height and weight. Spearman test showed that there was very weak correlation between ferritin and hemoglobin levels (<i>r</i><sub><i>s</i></sub> = .163). Our conclusions were that iron deficiency without anemia is very frequent among children starting first year of school. Regression models show that ferritin levels cannot be predicted by independent variables like status of height and weight on <i>Z</i>-score charts, age, gender, and anemia.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2018 ","pages":"8906258"},"PeriodicalIF":2.9,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/8906258","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36177992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Relation of Food Insecurity and Hemoglobin Level in Preschool Aged Children. 学龄前儿童食物不安全与血红蛋白水平的关系
IF 2.9
Anemia Pub Date : 2018-01-15 eCollection Date: 2018-01-01 DOI: 10.1155/2018/3950687
Élida Mara Braga Rocha, Luiz Carlos de Abreu, Amanda Forster Lopes, Claudio Leone, Patrícia Dore Vieira, Italla Maria Pinheiro Bezerra, Sophia Cornbluth Szarfarc
{"title":"Relation of Food Insecurity and Hemoglobin Level in Preschool Aged Children.","authors":"Élida Mara Braga Rocha,&nbsp;Luiz Carlos de Abreu,&nbsp;Amanda Forster Lopes,&nbsp;Claudio Leone,&nbsp;Patrícia Dore Vieira,&nbsp;Italla Maria Pinheiro Bezerra,&nbsp;Sophia Cornbluth Szarfarc","doi":"10.1155/2018/3950687","DOIUrl":"https://doi.org/10.1155/2018/3950687","url":null,"abstract":"<p><strong>Background: </strong>The iron deficiency anemia is a worldwide public problem, especially in developing countries, related to increased body needs and inadequate supply of iron from the diet.</p><p><strong>Objective: </strong>To analyze the association of food insecurity with hemoglobin concentration and the prevalence of anemia in preschool aged children in the city of Taubaté, São Paulo, Brazil.</p><p><strong>Methods: </strong>A cross-sectional study was conducted with 306 children of preschool age. The nutritional status was assessed according to hemoglobin level and anthropometric indicators. Socioeconomic data and Brazilian Household Food Insecurity Measurement Scale (EBIA) results were obtained from interview with parents.</p><p><strong>Results: </strong>The prevalence of anemia was around 19% of preschool aged children and 41.2% families presented food insecurity. The anthropometric indicators were not associated with food insecurity and even though the bivariate analysis demonstrated that mild food insecurity affects the hemoglobin level, after adjusting the multivariate model this association lost significance (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>The prevalence of anemia of 19.2% and the household food insecurity was found among 42.2% of the population.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2018 ","pages":"3950687"},"PeriodicalIF":2.9,"publicationDate":"2018-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/3950687","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35938787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Ferric Carboxymaltose as Treatment in Women with Iron-Deficiency Anemia. 羧麦芽糖铁治疗妇女缺铁性贫血。
IF 2.9
Anemia Pub Date : 2017-01-01 Epub Date: 2017-04-13 DOI: 10.1155/2017/9642027
Melvin H Seid, Angelia D Butcher, Ashwin Chatwani
{"title":"Ferric Carboxymaltose as Treatment in Women with Iron-Deficiency Anemia.","authors":"Melvin H Seid,&nbsp;Angelia D Butcher,&nbsp;Ashwin Chatwani","doi":"10.1155/2017/9642027","DOIUrl":"https://doi.org/10.1155/2017/9642027","url":null,"abstract":"<p><p><i>Objective</i>. To evaluate safety and efficacy of intravenous ferric carboxymaltose (FCM) versus standard medical care (SMC) for iron-deficiency anemia (IDA) in postpartum women and women with heavy menstrual bleeding. <i>Study Design</i>. This open-label, multicenter study randomized women with IDA (hemoglobin ≤ 11.0 g/dL) to single doses of FCM (15 mg/kg [maximum 1000 mg]) or SMC (this treatment was determined by the investigator and there may have been no treatment). Safety data (primary outcome) were collected for 30 days. <i>Results</i>. Of 2045 subjects enrolled (FCM: <i>n</i> = 1023; SMC: <i>n</i> = 1022), 996 received FCM and 1022 received SMC. At least 1 serious adverse event (AE) was reported by 0.6% and 2.2% of subjects in the FCM and SMC groups, respectively; none were considered treatment related. The difference in serious AEs was primarily due to higher rates of uterine leiomyoma, uterine hemorrhage, and menorrhagia in SMC subjects with heavy menstrual bleeding. Common AEs were generally predictable, with higher rates of infusion site reactions in FCM subjects and gastrointestinal AEs in SMC subjects. Mean hemoglobin increases were greater in the FCM group than the SMC group. <i>Conclusion</i>. FCM was well tolerated and effectively increased mean hemoglobin levels in postpartum women or women with heavy menstrual bleeding and IDA. This trial is registered with ClinicalTrials.gov, NCT00548860.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2017 ","pages":"9642027"},"PeriodicalIF":2.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/9642027","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34981065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Efficacy and Tolerability of Intravenous Ferric Carboxymaltose in Patients with Iron Deficiency at a Hospital Outpatient Clinic: A Retrospective Cohort Study of Real-World Clinical Practice. 医院门诊静脉注射羧麦芽糖铁治疗缺铁患者的疗效和耐受性:一项现实世界临床实践的回顾性队列研究。
IF 2.9
Anemia Pub Date : 2017-01-01 Epub Date: 2017-07-03 DOI: 10.1155/2017/3106890
António Robalo Nunes, Ana Palricas Costa, Sara Lemos Rocha, Ana Garcia de Oliveira
{"title":"Efficacy and Tolerability of Intravenous Ferric Carboxymaltose in Patients with Iron Deficiency at a Hospital Outpatient Clinic: A Retrospective Cohort Study of Real-World Clinical Practice.","authors":"António Robalo Nunes,&nbsp;Ana Palricas Costa,&nbsp;Sara Lemos Rocha,&nbsp;Ana Garcia de Oliveira","doi":"10.1155/2017/3106890","DOIUrl":"https://doi.org/10.1155/2017/3106890","url":null,"abstract":"<p><p>Ferric carboxymaltose (FCM) is an intravenous iron formulation to correct iron deficiency. Although its use has been extensively studied in clinical trials, real-world evidence regarding FCM treatment is scarce. Our aim was to evaluate the efficacy and tolerability of FCM treatment in patients with iron deficiency, with or without anemia, at a hospital outpatient clinic. Data was collected retrospectively from medical records. During this 2-year study, 459 patients were included. Mean age was 58.6 ± 17.5 years and most patients received cumulative FCM doses of 501-1000 mg (63.2%). Six weeks after administration of FCM, efficacy endpoints hemoglobin increase ≥2 g/dL, hemoglobin increase ≥3 g/dL, and transferrin saturation > 20% were attained by 41%, 20%, and 63% of patients, respectively. Patients who received higher FCM doses showed significant reduced odds of not achieving hemoglobin increase ≥2 g/dL (501-1000 mg, adjusted odds ratio [OR]: 0.34, 95% confidence interval [CI] 0.18-0.62; 1001-3000 mg, OR: 0.19, 95% CI 0.07-0.49), compared to 500 mg doses. Treatment-emergent adverse events were documented in <4% of patients. In conclusion, FCM treatment was effective and well-tolerated by outpatients with iron deficiency at a hospital clinic, and its dosage should be adjusted to improve iron deficiency management in clinical practice.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2017 ","pages":"3106890"},"PeriodicalIF":2.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/3106890","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35275374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Low Hemoglobin among Pregnant Women in Midwives Practice of Primary Health Care, Jatinangor, Indonesia: Iron Deficiency Anemia or β-Thalassemia Trait? 印度尼西亚贾提南戈尔初级卫生保健助产士的低血红蛋白孕妇:缺铁性贫血或β-地中海贫血特征?
IF 2.9
Anemia Pub Date : 2017-01-01 Epub Date: 2017-05-29 DOI: 10.1155/2017/6935648
Ari Indra Susanti, Edhyana Sahiratmadja, Gatot Winarno, Adhi Kristianto Sugianli, Herman Susanto, Ramdan Panigoro
{"title":"Low Hemoglobin among Pregnant Women in Midwives Practice of Primary Health Care, Jatinangor, Indonesia: Iron Deficiency Anemia or <i>β</i>-Thalassemia Trait?","authors":"Ari Indra Susanti,&nbsp;Edhyana Sahiratmadja,&nbsp;Gatot Winarno,&nbsp;Adhi Kristianto Sugianli,&nbsp;Herman Susanto,&nbsp;Ramdan Panigoro","doi":"10.1155/2017/6935648","DOIUrl":"https://doi.org/10.1155/2017/6935648","url":null,"abstract":"Low hemoglobin (Hb) or anemia is common among pregnant women in developing countries which may cause adverse pregnancy outcomes and maternal deaths. Our study aimed to assess Hb level measured by midwives in primary health care facility at rural area of Jatinangor, Indonesia, and to explore whether the anemia was due to iron deficiency (IDA) or β-thalassemia trait (β-TT). Pregnant women (n = 105) had finger prick test for Hb level during a regular antenatal care examination from October to November 2016. Hb level by finger prick test was compared with venous blood, measured by complete blood count (CBC). Indices including MCV and MCH and indices of Shine & Lal, Mentzer, Srivastava, Engels & Frase, Ehsani, and Sirdah were analyzed to differentiate anemia due to IDA and anemia due to suspect β-TT. HbA2 was measured to confirm β-TT. Anemic pregnant women were found in 86.7% by finger prick test compared to 21.9% (n = 23) by CBC. The prevalence of β-TT in our study was 5.7%. Hb measurement among pregnant women in low resource area is highly important; however, finger prick test in this study showed a high frequency of anemia which may lead to iron oversupplementation. A standard CBC is encouraged; MCV and MCH would help midwives to identify β-TT.","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2017 ","pages":"6935648"},"PeriodicalIF":2.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/6935648","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35105992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
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