Anemia最新文献

{"title":"REGAIN STUDY: Retrospective Study to Assess the Effectiveness, Tolerability, and Safety of Ferric Carboxymaltose in the Management of Iron Deficiency Anemia in Pregnant Women","authors":"Saleema Wani, Mariyam Noushad, Shabana Ashiq","doi":"10.1155/2019/4640635","DOIUrl":"https://doi.org/10.1155/2019/4640635","url":null,"abstract":"Iron deficiency anemia (IDA) during pregnancy arises because of preexisting inadequate stores or complex physiological changes and can lead to serious maternal and fetal complications. Oral iron, either as iron sulfate or fumarate, with or without folic acid, is the most commonly used treatment for IDA in pregnancy. Intravenous (IV) iron has a role in the treatment of IDA in pregnancy, particularly in women who present late, display severe anemia (Hb ≤ 9 g/dL), or risk factors, and are intolerant/noncompliant of oral iron. Previously, administration of IV iron was minimal, owing to potentially serious anaphylactic reactions. Recently, new IV iron products have been developed, offering better compliance, tolerability, efficacy, and a good safety profile. Our study aimed to assess the effectiveness, safety, and tolerability of IV ferric carboxymaltose (FCM) in the treatment of IDA in pregnant women in the UAE. Data from 1001 pregnant women who received at least one administration of FCM (500, 1000, or 1500 mg) during their second or third trimester of pregnancy (2 years backward from study initiation) were collected retrospectively from electronic medical records at Corniche Hospital, Abu Dhabi, UAE. Results showed that 41.4% of the women were able to achieve an increase of ≥2 g/dL in blood hemoglobin overall. A change of ≥2 g/dL was achieved by 27.5% of women administered a dose of 500 mg, 39.2% of women administered a dose of 1000 mg, and 63.9% of women administered a dose of 1500 mg of IV FCM. This indicates a directly proportional relationship between increasing IV FCM dose and the increase of ≥2 g/dL in blood hemoglobin. A total of 7 (0.7%) women reported mild, nonserious adverse events during the study. Within the limits of this retrospective study, IV FCM therapy was safe and effective in increasing the mean hemoglobin of pregnant women with IDA.","PeriodicalId":46055,"journal":{"name":"Anemia","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2019-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/4640635","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48961377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anemia Prevalence after Iron Supplementation among Pregnant Women in Midwifes Practice of Primary Health Care Facilities in Eastern Indonesia.","authors":"Merry M V Seu, Johanes C Mose, Ramdan Panigoro, Edhyana Sahiratmadja","doi":"10.1155/2019/1413906","DOIUrl":"10.1155/2019/1413906","url":null,"abstract":"<p><strong>Background: </strong>Iron deficiency anemia (IDA) in pregnant women is common, and iron supplementation is given during pregnancy to reduce birth complication. This study aimed to explore the prevalence of anemia and type of anemia after iron supplementation among pregnant women in the eastern part of Indonesia.</p><p><strong>Methods: </strong>A cross-sectional study design was conducted between January and March 2019 in three Primary Health Care (PHC) facilities at Kupang, West Timor. After consent, pregnant women who had taken their iron supplementation for at least 3 months were asked for iron pills intake by using a self-designed questionnaire and by counting the pills leftover. Complete blood count examination was performed, and the type of anemia was assessed using Shine and Lal index (SLI; MCV <i>∗</i> MCV <i>∗</i> MCH/100) to determine whether anemia was due to iron deficiency or <i>β</i>-thalassemia trait (<i>β</i>-TT). In a subset of iron tablets distributed in the PHCs, Fe-concentration was measured.</p><p><strong>Results: </strong>Of 102 pregnant women included, only 25.5% had taken the pills with a pill count of >80%. Interestingly, Fe-concentration in the pills from three different PHC facilities varied between 75% and 100%. After iron supplementation, however, anemia was detected in 34.3%, and based on SLI, 14.7% was suspected because of iron deficiency and 19.6% was suspective of <i>β</i>-TT. Of note, nonanemic pregnant women (17.6%) had also low SLI, suggesting <i>β</i>-TT or other hemoglobinopathies.</p><p><strong>Conclusion: </strong>Assessment of Shine and Lal index as the first step to screen the type of anemia in pregnant women from a limited area is of potential value, especially because Indonesia is located in the thalassemia belt area. An integrative approach and counseling among pregnant women with <i>β</i>-TT and their partners will increase thalassemia awareness and optimal birth management.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2019 1","pages":"1413906"},"PeriodicalIF":2.2,"publicationDate":"2019-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42623417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors of Anaemia among Children under Five Years in the Hohoe Municipality, Ghana: A Case Control Study","authors":"P. Parbey, E. Tarkang, E. Manu, Hubert Amu, M. Ayanore, F. Y. Aku, S. A. Ziema, S. Bosoka, M. Adjuik, M. Kweku","doi":"10.1155/2019/2139717","DOIUrl":"https://doi.org/10.1155/2019/2139717","url":null,"abstract":"Background Anaemia is one of the major causes of death among children under five years in Ghana. We examined the risk factors of anaemia among children under five years in the Hohoe Municipality, Ghana. Methods This facility-based matched case control study recruited 210 children (70 cases and 140 controls) aged 6 to 59 months. Stratified and simple random sampling techniques were used to select mothers attending Child Welfare Clinic (CWC) for the screening of their children. Data were collected using a semistructured questionnaire. Finger prick blood was collected to estimate the haemoglobin (Hb) level and thick film was prepared to determine malaria parasitaemia. Axillary temperature was measured using an +electronic thermometer and anthropometric measurements were done using a weighing scale and inelastic tape measure. Continuous variables were presented as means and standard deviations and categorical variables as frequencies and proportions. Conditional logistic regression was used to determine the strength of association between the dependent and the independent variables. Statistical significance was considered at p value of <0.05. Results The prevalence of anaemia was high (53.8%), while children whose mothers received iron supplementation during pregnancy were 7.64 times more likely to be anaemic compared with those who did not [AOR=7.64 (95% CI:1.41-41.20.93); p=0.018]. Children with poor dietary diversity were 9.15 times more likely to have anaemia [AOR=9.15 (95% CI: 3.13-26.82); p< 0.001]; and children whose mothers were farmers and traders were 83% [AOR = 0.17 (95% CI: 0.05-0.60); p=0.006] and 79% [AOR=0.21 (95% CI: 0.06-0.74); p=0.014], respectively, less likely to have anaemia. Conclusion The biologic, intermediate, and underlying factors that were significantly associated with anaemia comprised maternal iron supplementation, poor dietary diversity, farmers, and traders. Given that iron supplementation during pregnancy did not protect children against anaemia, we recommend the child's nutritional dietary diversity is encouraged.","PeriodicalId":46055,"journal":{"name":"Anemia","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/2139717","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42896870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Study of Interleukin 6, Inflammatory Markers, Ferritin, and Hematological Profile in Rheumatoid Arthritis Patients with Anemia of Chronic Disease and Iron Deficiency Anemia.","authors":"Eman Tariq Ali,&nbsp;Azza Sajed Jabbar,&nbsp;Ali Nazar Mohammed","doi":"10.1155/2019/3457347","DOIUrl":"https://doi.org/10.1155/2019/3457347","url":null,"abstract":"<p><strong>Background: </strong>Interleukin-6 (IL-6) proinflammatory cytokine is associated with the pathogenesis of rheumatoid arthritis and development of anemia in it. This is a comparative study of inflammatory and hematological parameters in RA patients with anemia of chronic disease (ACD) and iron deficiency anemia (IDA). It aimed to demonstrate the changes in serum level of IL-6, ferritin level, and hematological parameters in different groups of patients with RA and to find out the potential correlation between serum level of IL-6 and ferritin level and the relationship between serum level of IL-6 and iron status.</p><p><strong>Methods: </strong>The study included 89 patients from both sexes divided into four groups (group 1: 30 iron deficiency anemia (IDA), 59 RA; group 2: 20 RA-COMBI; group 3: 23 RA-ACD; and group 4: 16 nonanemic RA). These different groups were compared with a healthy group of 50 healthy individuals. Different blood parameters (WBC, RBC, HGB, HCT, MCV, and MCH) have been evaluated. Serum concentrations of IL-6, hsCRP, anti-CCP, and ferritin were measured in all patients and healthy individual using enzyme-linked immunosorbent assay ELISA.</p><p><strong>Results: </strong>There were significant changes in most of blood parameters between the groups, and there was a significant increase in the levels of IL-6 among RA patients. This increase was highly significant among RA-ACD patients in particular, and this elevation has been directly correlated with clinical indices of disease activity such as hsCRP, ESR, anti-CCP, and ferritin. There was an inverse relationship between ferritin and all iron status parameter, such as RBC, HGB, and haematocrit.</p><p><strong>Conclusion: </strong>IL-6 and ferritin level estimation may be workable tests to differentiate the patients with IDA and ACD in RA.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2019 ","pages":"3457347"},"PeriodicalIF":2.9,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/3457347","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37216471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iron Deficiency Anemia among In-School Adolescent Girls in Rural Area of Bahir Dar City Administration, North West Ethiopia.","authors":"Getachew Mengistu,&nbsp;Muluken Azage,&nbsp;Hordofa Gutema","doi":"10.1155/2019/1097547","DOIUrl":"10.1155/2019/1097547","url":null,"abstract":"<p><strong>Background: </strong>Anemia is a major public health problem worldwide. Adolescent girls are the most vulnerable group of population due to different reasons. The aim of this study was to assess the prevalence of anemia and associated factors among school adolescent girls in rural towns of Bahir Dar City Administration, North West Ethiopia.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from March 5 to April 15, 2017, on 443 randomly selected school adolescent girls. Data were collected using pretested structured questionnaire and anthropometric measurements. Blood sample was also collected to assess the hemoglobin (Hgb) value of study participants. SPSS version 20 was used to analyze data. Descriptive statistics were used to describe data. Bivariate and multivariable logistic regression models were used to identify the associated factors with the outcome variable. Crude and adjusted odds ratios with 95% confidence interval (CI) were calculated to identify the variables significantly associated with the outcome variable.</p><p><strong>Result: </strong>The prevalence of anemia was 11.1%. Household family size <i>[AOR=3.2, 95%CI (1.29-7.89)]</i>, average household monthly income <500 ETB <i>[AOR=10; 95%CI (2.49-41.26)]</i>, 501-1000 ETB <i>[AOR=6, 95%CI (2.54-14.33)]</i>, history of intestinal parasitic infection <i>[AOR=2.7; 95% CI (1.19-6.21)]</i>, duration of menstruation flow <i>[AOR=2.4; 95%CI (1.08- 5.44)]</i>, and BMI for age <i>[AOR-3.2; 95% CI (1.43-7.05)]</i> were the predictors of anemia.</p><p><strong>Conclusion and recommendation: </strong>Anemia was a mild public health problem among school adolescent girls in the study area. Household monthly income, family size, intestinal parasite infections, duration of menstruation, and BMI for age are predictors of anemia. Thus, intervention strategies should focus on prevention and early treatment of intestinal parasite, nutritional education, screening, and iron supplementation programs to prevent anemia among school adolescent girls.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2019 ","pages":"1097547"},"PeriodicalIF":2.9,"publicationDate":"2019-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/1097547","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37178865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comorbidity of Glucose-6-Phosphate Dehydrogenase Deficiency and Sickle Cell Disease Exert Significant Effect on RBC Indices.","authors":"Samuel Antwi-Baffour,&nbsp;Jonathan Kofi Adjei,&nbsp;Peter Owadee Forson,&nbsp;Stephen Akakpo,&nbsp;Ransford Kyeremeh,&nbsp;Mahmood Abdulai Seidu","doi":"10.1155/2019/3179173","DOIUrl":"https://doi.org/10.1155/2019/3179173","url":null,"abstract":"<p><strong>Background: </strong>Glucose-6-phosphate dehydrogenase (G6PD) converts glucose-6-phosphate into 6-phosphogluconate in the pentose phosphate pathway and protects red blood cells (RBCs) from oxidative damage. Their deficiency therefore makes RBCs prone to haemolysis. Sickle cell disease (SCD) on the other hand is a hereditary blood disorder in which there is a single nucleotide substitution in the codon for amino acid 6 substituting glutamic acid with valine. SCD patients are prone to haemolysis due to the shape of their red blood cells and if they are deficient in G6PD, the haemolysis may escalate. Reported studies have indicated variations in the prevalence of G6PD deficiency in SCD patients and as such further work is required. The aim of this study was therefore to estimate the incidence of G-6-PD deficiency among SCD patients and to determine its impact on their RBC parameters as a measure of incidence of anaemia.</p><p><strong>Methods: </strong>A total of 120 clinically diagnosed SCD patients of genotypes HbSS and HbSC were recruited into the study. About 5ml of blood was collected via venipuncture from each patient and used to run G6PD, full blood count, and haemoglobin (Hb) electrophoresis tests. The data were analyzed using SPSS version 20 and Graphpad prism.</p><p><strong>Result: </strong>G6PD deficiency was detected in 43 (35.83%) of the participants made up of 16 (13.33%) males and 27 (22.50%) females of whom 17 (14.17%) had partial deficiency and 10 (8.33%) full deficiency. Statiscally significant differences p=0.036 and p=0.038 were established between the Hb concentration of the participants having a G6PD deficiency and those with normal G6PD activity for males and females, respectively.</p><p><strong>Conclusion: </strong>From the results obtained, it implies that G6PD deficiency may increase the severity of anaemia in SCD patients. There is therefore the need to screen all SCD patients for G6PD deficiency to ensure that their condition is not exacerbated during treatment.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2019 ","pages":"3179173"},"PeriodicalIF":2.9,"publicationDate":"2019-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/3179173","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37178867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Efficacy and Tolerability of Intravenous Ferric Carboxymaltose in Patients with Iron Deficiency at a Hospital Outpatient Clinic: A Retrospective Cohort Study of Real-World Clinical Practice\".","authors":"António Robalo Nunes,&nbsp;Ana Palricas Costa,&nbsp;Sara Lemos Rocha,&nbsp;Ana Garcia de Oliveira","doi":"10.1155/2019/9242607","DOIUrl":"https://doi.org/10.1155/2019/9242607","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1155/2017/3106890.].</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2019 ","pages":"9242607"},"PeriodicalIF":2.9,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/9242607","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36924006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Anemia and Iron Deficiency among Palestinian Pregnant Women and Its Association with Pregnancy Outcome.","authors":"Mahmoud A Srour, Samah S Aqel, Khaled M Srour, Khalid R Younis, Fekri Samarah","doi":"10.1155/2018/9135625","DOIUrl":"10.1155/2018/9135625","url":null,"abstract":"<p><strong>Background: </strong>Anemia is a public health problem especially among pregnant women. This study aimed to investigate the prevalence of anemia and iron deficiency among pregnant women and its association with pregnancy outcome in Hebron Governorate in southern Palestine.</p><p><strong>Methods: </strong>This is a cross-sectional study that included 300 pregnant women in their first trimester and 163 babies. Maternal anthropometric and socioeconomic and newborns' data were collected. Complete blood count for study subjects and maternal serum ferritin were measured.</p><p><strong>Results: </strong>The prevalence of iron deficiency anemia among pregnant women was 25.7% and 52% of them had depleted iron stores. When pregnant women were grouped into three hemoglobin (Hb) tertile groups, a significant difference was observed between maternal Hb and newborns' birth weight (<i>P</i>= 0.009), height (<i>P</i>= 0.022), head circumference (<i>P</i>= 0.017), and gestational age (<i>P</i>= 0.012). There was a significant association between maternal serum ferritin and frequency of low birth weight (<i>P</i>= 0.001) and frequency of preterm delivery (<i>P</i>= 0.003). No significant association was observed between maternal anthropometric measures or the socioeconomic status and pregnancy outcomes.</p><p><strong>Conclusion: </strong>Iron deficiency is a moderate public health problem among the study subjects. Maternal Hb and serum ferritin significantly affect pregnancy outcomes.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2018 ","pages":"9135625"},"PeriodicalIF":2.9,"publicationDate":"2018-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36892161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnitude of Anemia and Associated Factors among Pregnant Women Attending Antenatal Care in Public Hospitals of Ilu Abba Bora Zone, South West Ethiopia: A Cross-Sectional Study.","authors":"Adamu Kenea,&nbsp;Efrem Negash,&nbsp;Lemi Bacha,&nbsp;Negash Wakgari","doi":"10.1155/2018/9201383","DOIUrl":"https://doi.org/10.1155/2018/9201383","url":null,"abstract":"<p><strong>Background: </strong>Anemia is a global public health problem affecting all population particularly pregnant women. Hence, this study assessed the magnitude of anemia and associated factors among pregnant.</p><p><strong>Methods: </strong>Institution based cross-sectional study was conducted among 416 pregnant women attending antenatal clinic in three public hospitals of Ilu Aba Bora zone. The study participants were selected by proportional allocation based on the number of pregnant women that the respective health facilities contain. Semistructured questionnaire was used for data collection. Midupper arm circumference was employed to assess the nutritional status and standard mood depression assessment tool was used to assess depression. Data were centered and analyzed using SPSS version 20.0. Logistic regression analyses were used to see the association of different variables.</p><p><strong>Results: </strong>In this study, 31.5% of pregnant women were anemic. In addition, having family size five and above [AOR = 2.97, 95% CI (1.69, 5.27)], being rural resident [AOR=2.74, (95%CI) (2.11, 5.06)], had a higher odds of anemia. Similarly, having soil transmitted helminthes infection [AOR= 3.19, 95% CI (1.5, 6.65)] and history of malaria infection in the last one year [AOR= 3.10, 95% CI (2.10, 5.06)] had also a higher odds anemia during pregnancy. Moreover, being undernourished [AOR= 2.74 95% CI (1.34, 5.57)] was negatively associated with magnitude of anemia.</p><p><strong>Conclusions: </strong>The magnitude of anemia among pregnant women was found to be significant. Residence, family sizes, history of malaria infection during the last one year, and undernourishment were significantly associated with anemia during pregnancy.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2018 ","pages":"9201383"},"PeriodicalIF":2.9,"publicationDate":"2018-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/9201383","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36817322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anemia among Women Attending Antenatal Care at the University of Gondar Comprehensive Specialized Referral Hospital, Northwest Ethiopia, 2017.","authors":"Wubet Worku Takele,&nbsp;Amare Tariku,&nbsp;Fasil Wagnew Shiferaw,&nbsp;Amare Demsie,&nbsp;Wondale Getinet Alemu,&nbsp;Degefaye Zelalem Anlay","doi":"10.1155/2018/7618959","DOIUrl":"10.1155/2018/7618959","url":null,"abstract":"<p><strong>Background: </strong>In Ethiopia, prenatal anemia is a major public health concern affecting both the health of the woman and babies. The World Health Organization recommends to conduct repeated prevalence studies concerning prenatal anemia . However, there is no recent evidence on the magnitude of the prenatal anemia. Therefore, the aim of this study was to determine the prevalence and the associated factors of prenatal anemia among women attending the Antenatal Care Clinic at the University of Gondar Referral Hospital.</p><p><strong>Methods: </strong>A facility-based cross-sectional quantitative study was conducted among 362 participants from June 03-July 08, 2017, at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia. The systematic random sampling technique was employed. Structured interviewer administered questionnaire was used. Human Immunodeficiency Virus (HIV) screening was conducted. Nutritional status of the participants was assessed. Blood sample was collected by capillary tube . Intestinal parasite was examined by stool wet mount test. HIV serostatus was detected. Anemia was defined as hemoglobin concentration below 11 g/dl. The multivariable logistic regression model was employed to identify associated factors and to control the possible effects of confounders.</p><p><strong>Result: </strong>The prevalence of anemia was 22.2% (95% CI: 18.11, 27.1%). The highest odds of anemia were observed among pregnant women with family size of >five [AOR = 3 (95% CI: 1.03, 8.65)], unprotected water source users, [AOR = 4.09 (95% CI: 1.75, 9.55)], HIV infected [AOR = 2.94(95% CI: 1.37, 6.35)], and multigravida women [AOR = 3.5 (95% CI: 1.35, 9.17)].</p><p><strong>Conclusion and recommendations: </strong>The prevalence of anemia among pregnant women attending the University of Gondar Referral Hospital was a moderate public health problem. Unprotected water source, large family size, Human Immunodeficiency Virus infection, and repeated pregnancies were factors that predicted anemia. Thus, prevention of Human Immunodeficiency Virus infection, family planning utilization, and accessing pure water are recommended.</p>","PeriodicalId":46055,"journal":{"name":"Anemia","volume":"2018 ","pages":"7618959"},"PeriodicalIF":2.9,"publicationDate":"2018-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/7618959","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36642525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}