PROGRESS IN PEDIATRIC CARDIOLOGY最新文献

{"title":"Cardiomyopathy in childhood cancer survivors: Etiology, pathophysiology, diagnosis, treatment, and screening","authors":"Pedro Ricardo Cabrera ,&nbsp;Isabella Dinelli ,&nbsp;Noah Baker ,&nbsp;Ashley Bates ,&nbsp;Ashleigh Torrance ,&nbsp;Induja Gajendran ,&nbsp;Hamayun Imran","doi":"10.1016/j.ppedcard.2024.101766","DOIUrl":"10.1016/j.ppedcard.2024.101766","url":null,"abstract":"<div><h3>Background</h3><div>There is an increase in childhood cancer survivors because of advancements in cancer treatment. Current overall survival of childhood cancer in developed nations is &gt;80 %. Increased survival is associated with an increase in long-term therapy-related adverse events. Cardiotoxicity from exposure to chemo- and radiation therapy may cause major short- and long-term sequelae.</div></div><div><h3>Aim of review</h3><div>The purpose of this article is to review current concepts about cardiotoxicity associated with pediatric cancer therapy including etiology, pathophysiology, diagnosis, treatment, and screening.</div></div><div><h3>Key scientific concepts of review</h3><div>Anthracycline drugs produce reactive oxygen species that cause damage to myocytes. Radiation therapy causes collagen replacement and fibrosis in the pericardium and myocardium. Acute complications include arrhythmias, decreased left ventricle (LV) function, and heart failure. Chronic complications occurring &gt;1 year after treatment initiation include coronary artery disease, valvular disease, and cardiomyopathy. These adverse events are observed mostly with high cumulative doses of anthracyclines (&gt;250 mg/m²) or radiation therapy (&gt;30 Gy). Additional risk factors such as preexisting cardiac illness, hypertension, dyslipidemia, and diabetes may contribute to adverse outcomes. Echocardiography is the most commonly used method of screening and diagnosis of cardiac dysfunction. In contrast, cardiac magnetic resonance imaging is more precise but also costly and requires sedation. Prevention of cardiotoxicity includes the use of dexrazoxane, enalapril, and methods to modify the dosage and delivery of chemo- and radiation therapy. Treatment of established cardiomyopathy may include interventions for LV preload and afterload reduction, implantable devices, and heart transplant. With emphasis on prevention, current guidelines recommend frequent screening echocardiography and individualized multimodal care for each patient. Further studies are justified to develop safe and effective alternatives to cardiotoxic cancer therapy regimens and improved treatments for established cardiomyopathy.</div></div>","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"75 ","pages":"Article 101766"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Analysis of buccal mucosa as a prognostic tool in children with arrhythmogenic cardiomyopathy” [Progress in Pediatric Cardiology 64 (2022) 101458]","authors":"Carlos Bueno-Beti ,&nbsp;Ella Field ,&nbsp;Adalena Tsatsopoulou ,&nbsp;Gregory Perry ,&nbsp;Mary N. Sheppard ,&nbsp;Elijah R. Behr ,&nbsp;Jeffrey E. Saffitz ,&nbsp;Juan Pablo Kaski ,&nbsp;Angeliki Asimaki","doi":"10.1016/j.ppedcard.2024.101783","DOIUrl":"10.1016/j.ppedcard.2024.101783","url":null,"abstract":"","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"75 ","pages":"Article 101783"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Feasibility of electrocardiogram screening in the USA prior to high school sport participation” [Prog Pediatr Cardiol 65 (2022) 101522]","authors":"Gabriel S. Krivenko ,&nbsp;Emily R. Ribeiro ,&nbsp;Scott Walker ,&nbsp;Coralis Mercado-Gonzalez ,&nbsp;Shawn Sima ,&nbsp;Evan Ernst ,&nbsp;Svjetlana Tisma-Dupanovic ,&nbsp;Gul H. Dadlani","doi":"10.1016/j.ppedcard.2024.101793","DOIUrl":"10.1016/j.ppedcard.2024.101793","url":null,"abstract":"","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"75 ","pages":"Article 101793"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143084205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sodium thiopental-induced atrial flutter","authors":"Nihal Akçay ,&nbsp;Helen Bornaun ,&nbsp;Demet Tosun ,&nbsp;İlyas Bingöl","doi":"10.1016/j.ppedcard.2024.101769","DOIUrl":"10.1016/j.ppedcard.2024.101769","url":null,"abstract":"<div><h3>Background</h3><div>Convulsive status epilepticus (CSE) is a critical neurological emergency that requires immediate intervention. Sodium thiopental is frequently used to induce coma in cases of refractory CSE; however, its use can be complicated by severe cardiac side effects.</div></div><div><h3>Case presentation</h3><div>We report a case of a 7-year-old female with super-refractory status epilepticus secondary to West syndrome, who developed supraventricular tachycardia (SVT) and atrial flutter during a thiopental infusion. Despite receiving multiple anti-seizure medications, including midazolam, ketamine, and thiopental, the patient exhibited persistent seizures. On the fourth of thiopental infusion, she developed SVT and atrial flutter, which resolved following the administration of beta-blockers and the discontinuation of thiopental. Continuous monitoring and prompt intervention led to the successful restoration of sinus rhythm. The patient was discharged on the 28th day of hospitalization.</div></div><div><h3>Discussion</h3><div>This case underscores the critical importance of vigilant cardiac monitoring during thiopental infusion due to its potential to induce severe arrhythmias. The pathophysiology of thiopental-induced cardiac complications involves its negative inotropic and chronotropic effects, necessitating careful patient selection and proactive management.</div></div><div><h3>Conclusion</h3><div>Sodium thiopental remains a viable option for managing refractory CSE, but its use requires careful consideration of cardiac risks. Continuous cardiac monitoring and a multidisciplinary approach are essential for optimizing patient outcomes. Further research is needed to elucidate the mechanisms underlying thiopental-induced cardiac complications and to develop preventive strategies.</div></div>","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"75 ","pages":"Article 101769"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Preoperative imaging and surgical repair of a coronary sinus septal defect: A case report” [Prog Pediatr Cardiol 65 (2022) 101513]","authors":"Gabriel Krivenko ,&nbsp;Brenden Maag ,&nbsp;Jennifer S. Nelson ,&nbsp;Peace Madueme ,&nbsp;Kathryn Douglas ,&nbsp;Maria Malaya Dorotan-Guevara","doi":"10.1016/j.ppedcard.2024.101795","DOIUrl":"10.1016/j.ppedcard.2024.101795","url":null,"abstract":"","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"75 ","pages":"Article 101795"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Case report: Acute lymphoblastic leukemia presenting as myocarditis” [Prog Pediatr Cardiol 65 (2022) 101511]","authors":"Emily R. Ribeiro ,&nbsp;Irina Nagovsky ,&nbsp;Peace Madueme ,&nbsp;Elena Rueda-de-Leon ,&nbsp;Gul H. Dadlani ,&nbsp;Eva Nunlist","doi":"10.1016/j.ppedcard.2024.101792","DOIUrl":"10.1016/j.ppedcard.2024.101792","url":null,"abstract":"","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"75 ","pages":"Article 101792"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Link between nocturnal hypoventilation and hypoxia on arrhythmias/CV morbidity in neuromuscular disorders” [Prog Pediatr Cardiol 68 (2022) 101601]","authors":"Xilei Xu Chen,&nbsp;Geovanny F. Perez","doi":"10.1016/j.ppedcard.2024.101787","DOIUrl":"10.1016/j.ppedcard.2024.101787","url":null,"abstract":"","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"75 ","pages":"Article 101787"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Heart rate variability in children with sleep disordered breathing” [Progress in Pediatric Cardiology 68 (2023) 101620]","authors":"Alberto F. Monegro,&nbsp;Kunal Gawri","doi":"10.1016/j.ppedcard.2024.101788","DOIUrl":"10.1016/j.ppedcard.2024.101788","url":null,"abstract":"","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"75 ","pages":"Article 101788"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Post-operative sleep and activity patterns in critically ill children after cardiac surgery” [Prog Pediatr Cardiol 68 (2023) 101603]","authors":"Amanda B. Hassinger ,&nbsp;Jessica A. Berger ,&nbsp;Othman A. Aljohani ,&nbsp;Sapna R. Kudchadkar","doi":"10.1016/j.ppedcard.2024.101786","DOIUrl":"10.1016/j.ppedcard.2024.101786","url":null,"abstract":"","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"75 ","pages":"Article 101786"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Aortic arch atresia in Williams syndrome” [Prog Pediatr Cardiol 65 (2022) 101510]","authors":"Stefanie M. Miller ,&nbsp;Peace C. Madueme ,&nbsp;Peter D. Wearden ,&nbsp;Jennifer S. Nelson","doi":"10.1016/j.ppedcard.2024.101794","DOIUrl":"10.1016/j.ppedcard.2024.101794","url":null,"abstract":"","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"75 ","pages":"Article 101794"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143084206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}