Case Reports in Pathology最新文献_第7页

A Twisted Tale: A Case of Intestinal Volvulus in an 85-Year-Old Female. 一个扭曲的故事：一例85岁女性肠扭转。

IF 0.4

Case Reports in Pathology Pub Date : 2025-12-22 eCollection Date: 2025-01-01 DOI: 10.1155/crip/6843513

Henry Elsenpeter, Paxten Wahlund, Selly Strauch, Susan Roe

{"title":"A Twisted Tale: A Case of Intestinal Volvulus in an 85-Year-Old Female.","authors":"Henry Elsenpeter, Paxten Wahlund, Selly Strauch, Susan Roe","doi":"10.1155/crip/6843513","DOIUrl":"10.1155/crip/6843513","url":null,"abstract":"Medicolegal death investigation (MDI) includes sudden and unexpected deaths, with the most common being cardiovascular deaths, cerebral, pulmonary, and cancer causes. Less commonly, gastrointestinal conditions can occur, and most conditions are symptomatic. Occasionally, pain is masked or absent. Of the many intestinal conditions that may cause death, intestinal volvulus occurs in all ages and is part of the larger intestinal obstruction disease states. The individual in our report was an active, articulate 85-year-old female in excellent health; her medical history was positive only for hypothyroidism, treated for over 30 years with Synthroid. She died following vague abdominal complaints and nausea following a meal. At autopsy, a volvulus of the ileum and adjacent mesentery was present. The ileum was necrotic, and 700 cc of bloody, dark peritoneal fluid was present. Major arteries, including celiac, superior, and inferior mesenteric arteries, were patent. A volvulus occurs when the bowel twists upon its associated mesentery, causing obstruction within the intestine, vascular compromise of the supporting vessels in the mesentery, and ultimate distal ischemia of the affected bowel. Correct assessment in this case provided answers for the family and allowed correct death certificate classification.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"2025 ","pages":"6843513"},"PeriodicalIF":0.4,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12747074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145865344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Case of Collision Tumor at the Periampullary Region. 壶腹周围碰撞性肿瘤1例。

IF 0.4

Case Reports in Pathology Pub Date : 2025-12-22 eCollection Date: 2025-01-01 DOI: 10.1155/crip/7777605

Kshitija Kale, Vikram Chaudhari, Vikas Ostwal, Shailesh V Shrikhande, Kedar Deodhar

{"title":"A Rare Case of Collision Tumor at the Periampullary Region.","authors":"Kshitija Kale, Vikram Chaudhari, Vikas Ostwal, Shailesh V Shrikhande, Kedar Deodhar","doi":"10.1155/crip/7777605","DOIUrl":"10.1155/crip/7777605","url":null,"abstract":"Collision tumors are rare neoplasms composed of two histologically distinct components without a transitional zone. Only nine cases involving periampullary adenocarcinoma and neuroendocrine tumor (NET) have been reported. A 55-year-old male presented with recurrent fever and jaundice. Imaging and biopsy revealed a periampullary lesion diagnosed as tubule-villous adenoma with high-grade dysplasia. He underwent pylorus-preserving pancreatoduodenectomy. Histology revealed moderately differentiated intestinal-type adenocarcinoma (pT2N1) with regional lymph node metastasis. Additionally, a 2-mm well-differentiated NET was found 2.5 cm proximal to the primary tumor, also with nodal metastasis. Immunohistochemistry confirmed distinct lineages, fulfilling the criteria for a collision tumor. This case represents a rare periampullary collision tumor with both adenocarcinoma and NET components showing independent lymph node metastases. The absence of transitional zones rules out MiNEN. This report underscores the importance of thorough pathological assessment and adds to the limited literature on the behavior and prognosis of periampullary collision tumors.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"2025 ","pages":"7777605"},"PeriodicalIF":0.4,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12747095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145864836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rare Mucinous Tumors of the Alveolar Space: Two Case Reports. 罕见肺泡间隙粘液性肿瘤2例报告。

IF 0.4

Case Reports in Pathology Pub Date : 2025-12-11 eCollection Date: 2025-01-01 DOI: 10.1155/crip/6177155

Calista Sha, Michael Esposito, Paul C Lee

引用次数: 0

Primary Intracranial Sarcomatoid Yolk Sac Tumor With Unique Histology: A Case Report. 原发性颅内独特组织学肉瘤样卵黄囊瘤1例报告。

IF 0.4

Case Reports in Pathology Pub Date : 2025-12-07 eCollection Date: 2025-01-01 DOI: 10.1155/crip/2011129

Jessica A Ortega-Balderas, Hayde S Ramos-Marrero, Raquel Garza-Guajardo, Oralia Barboza-Quintana, Barbara Saenz-Ibarra

引用次数: 0

Ominous Mediastinal Mass Revealing Ectopic Thyroid. 恶性纵隔肿块显示甲状腺异位。

IF 0.5

Case Reports in Pathology Pub Date : 2025-11-28 eCollection Date: 2025-01-01 DOI: 10.1155/crip/5583511

Cameron Summers, Gabriella Morey, Susana Ferra

引用次数: 0

Novel SZT2::MAST2 Fusion Detected in Salivary Duct Carcinoma. 涎腺导管癌中发现新型SZT2::MAST2融合。

IF 0.5

Case Reports in Pathology Pub Date : 2025-11-28 eCollection Date: 2025-01-01 DOI: 10.1155/crip/3728015

Adam Bedeir, Guilherme Rabinowits, Tolulope Adeyelu, Matthew J Oberley, Mark G Evans

引用次数: 0

Cribriform Adenocarcinoma of the Nasal Cavity Harboring a Novel NAP1L1::PRKD1 Fusion, Expanding the Molecular Landscape of Minor Salivary Gland Tumors. 鼻腔筛状腺癌携带一种新的NAP1L1::PRKD1融合，扩大了小唾液腺肿瘤的分子格局。

IF 0.5

Case Reports in Pathology Pub Date : 2025-11-27 eCollection Date: 2025-01-01 DOI: 10.1155/crip/9431983

Ernesto Martinez Duarte, Ross Germani, Charles Nicholson, Amy Baruch, Trisha Shattuck

引用次数: 0

A Rare Case of Adult Rhabdomyoma in the Parapharyngeal Space: Diagnostic Challenges and Surgical Management. 成人咽旁间隙横纹瘤1例：诊断挑战及手术处理。

IF 0.5

Case Reports in Pathology Pub Date : 2025-10-31 eCollection Date: 2025-01-01 DOI: 10.1155/crip/1626816

Alkmini Gatsounia, Pinelopi Bosgana, Gerasimos Danielides, Athanasios Vlachodimitropoulos, Hamida Kurabi, Spyridon Lygeros

{"title":"A Rare Case of Adult Rhabdomyoma in the Parapharyngeal Space: Diagnostic Challenges and Surgical Management.","authors":"Alkmini Gatsounia, Pinelopi Bosgana, Gerasimos Danielides, Athanasios Vlachodimitropoulos, Hamida Kurabi, Spyridon Lygeros","doi":"10.1155/crip/1626816","DOIUrl":"10.1155/crip/1626816","url":null,"abstract":"Introduction: Adult rhabdomyoma (ARM) is an exceedingly rare benign neoplasm accounting for less than 2% of all striated muscle tumors. Originating from striated muscle cells, it primarily occurs in the head and neck region but is particularly rare in the parapharyngeal space.Case presentation: We report a case of a 64-year-old male patient who presented with a 6-month history of progressive dysphagia and globus pharyngeus. CT and MRI scans revealed a well-defined multilobular mass in the right parapharyngeal space. Surgical excision was performed, and histopathological evaluation confirmed ARM. ARM diagnosis presents a challenge due to nonspecific clinical and radiological manifestations. Histopathological examination remains the gold standard for definitive diagnosis. Surgical excision is the treatment of choice, and close postoperative monitoring is crucial due to high recurrence rates.Conclusion: This case highlights the diagnostic challenges and treatment modalities for ARM in a rare anatomical location. A multidisciplinary approach incorporating radiological, cytological, and histopathological evaluations is essential for accurate diagnosis and effective management.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"2025 ","pages":"1626816"},"PeriodicalIF":0.5,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12595224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145483370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Autopsy Case Report of an Infant Born to a Diabetic Mother, With Review of Literature-A Pandora's Box of Pathologies. 一名糖尿病母亲所生婴儿的尸检病例报告，并复习文献-病理的潘多拉盒子。

IF 0.5

Case Reports in Pathology Pub Date : 2025-10-26 eCollection Date: 2025-01-01 DOI: 10.1155/crip/6662921

Gurpreet Kaur, Raghav Sharma, Vikram Singh, Ankur Ahuja, Somasundaram Venkatesan

{"title":"An Autopsy Case Report of an Infant Born to a Diabetic Mother, With Review of Literature-A Pandora's Box of Pathologies.","authors":"Gurpreet Kaur, Raghav Sharma, Vikram Singh, Ankur Ahuja, Somasundaram Venkatesan","doi":"10.1155/crip/6662921","DOIUrl":"10.1155/crip/6662921","url":null,"abstract":"Gestational diabetes mellitus (GDM) affects approximately 2%-17.8% of pregnancies, with preexisting diabetes also contributing to significant fetal risks. Despite advancements in obstetric and medical care, pregnancies complicated by maternal diabetes continue to carry a higher likelihood of fetal loss compared to nondiabetic pregnancies. Infants born to diabetic mothers (IDMs) are predisposed to complications such as birth trauma, respiratory difficulties, metabolic derangements including hypoglycemia and hypocalcemia, jaundice, increased blood viscosity, and various congenital anomalies-all potentially contributing to fetal mortality. We report the autopsy findings of a male IDM, born to a 25-year-old primigravida conceived via intrauterine insemination (IUI) with GDM, delivered at 38 weeks and 3 days of gestation, weighing 3.1 kg with reassuring Apgar scores at birth. Despite an apparently uncomplicated delivery and no immediate congenital anomalies detected, the infant developed sudden respiratory distress and unresponsiveness at 90 min of life, leading to unsuccessful resuscitation efforts. The autopsy revealed hallmark features of maternal-fetal glucose imbalance, including cardiopulmonary hypertrophy, hepatomegaly, immature lungs, pulmonary hypertension, and marked pancreatic islet cell hyperplasia. Inflammatory changes in the meninges and hypoxic neuronal injury were also observed. No structural malformations were identified. Although neonatal autopsies are inherently challenging, they provide critical insights that may influence neonatal care practices and guide future genetic counseling for affected families.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"2025 ","pages":"6662921"},"PeriodicalIF":0.5,"publicationDate":"2025-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12580034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intracholecystic Papillary Neoplasm With Associated Invasive Carcinoma, Accompanied by Tumor Thrombi of Hepatoid Adenocarcinoma: A Case Report. 胆囊内乳头状肿瘤伴浸润性癌伴肝样腺癌肿瘤血栓1例。

IF 0.5

Case Reports in Pathology Pub Date : 2025-10-03 eCollection Date: 2025-01-01 DOI: 10.1155/crip/7736309

Sho Yoshida, Yusuke Kouchi, Ryotaro Eto, Masayuki Ohtsuka, Takashi Kishimoto

{"title":"Intracholecystic Papillary Neoplasm With Associated Invasive Carcinoma, Accompanied by Tumor Thrombi of Hepatoid Adenocarcinoma: A Case Report.","authors":"Sho Yoshida, Yusuke Kouchi, Ryotaro Eto, Masayuki Ohtsuka, Takashi Kishimoto","doi":"10.1155/crip/7736309","DOIUrl":"10.1155/crip/7736309","url":null,"abstract":"Hepatoid adenocarcinoma (HAC) is a rare extrahepatic adenocarcinoma characterized by hepatocellular differentiation. HAC arising in the gallbladder is rare. We report a case of intracholecystic papillary neoplasm (ICPN) with HAC, most of which were tumor thrombi. The patient was a 78-year-old Japanese woman diagnosed with a gallbladder mass, detected by ultrasonography. She underwent cholecystectomy with lymph node dissection. Histopathological examination revealed exophytic papillary growth consistent with ICPN with associated invasive carcinoma. Notably, many tumor nests displayed characteristics of HAC, including eosinophilic granular cytoplasm and solid trabecular patterns. Immunohistochemically, tumor cells were positive for AFP, Glypican 3, and Hep Par 1 but negative for SALL4. Our findings underscore the importance of recognizing HAC components in gallbladder lesions, particularly in the context of ICPN with associated invasive carcinoma, as they may significantly impact patient prognosis.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"2025 ","pages":"7736309"},"PeriodicalIF":0.5,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12513791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0