Case Reports in Pathology最新文献_第7页

Progressive Nodular Histiocytosis: Report of a Case and Review of the Literature. 进行性结节性组织细胞增多症1例报告及文献复习。

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Case Reports in Pathology Pub Date : 2021-09-17 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5531820

Numbereye Numbere, Tatsiana Pukhalskaya, Blythe Bowman, Katelynn Campbell, Bruce Smoller

{"title":"Progressive Nodular Histiocytosis: Report of a Case and Review of the Literature.","authors":"Numbereye Numbere, Tatsiana Pukhalskaya, Blythe Bowman, Katelynn Campbell, Bruce Smoller","doi":"10.1155/2021/5531820","DOIUrl":"https://doi.org/10.1155/2021/5531820","url":null,"abstract":"Progressive nodular histiocytosis (PNH) is a rare condition characterized by progressive eruption of multiple yellowish-brown papules and nodules on the skin and mucous membranes. We present the case of a 37-year-old Caucasian man with gradually increased appearance of nodular lesions on the forehead and right temple. These lesions were initially diagnosed as xanthomas and did not respond to intralesional injections of triamcinolone. Additional biopsy revealed an intense dermal infiltrate of foamy mononuclear epithelioid cells with a minor admixture of plasma cells, lymphocytes, and scattered multinucleated giant cells. On immunohistochemical staining, the lesional cells were positive for CD163 and CD68 and negative for CD1a, thus confirming a mononuclear-macrophage lineage. The clinical presentation and the histological impression lead to the diagnosis of PNH. This condition could be challenging, mimicking microscopically similar lesions of the non-Langerhans cell histiocytosis group. Although uncommon, PNH stands out due to its clinical and microscopic features and should be taken into consideration in the differential diagnosis of cutaneous histiocytoses.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39453968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Multiple Primary Angiosarcomas of the Colon. 结肠多发原发性血管肉瘤。

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Case Reports in Pathology Pub Date : 2021-09-09 eCollection Date: 2021-01-01 DOI: 10.1155/2021/7237379

Sonja Radić, Mario Zovak, Anita Galović Marić, Stjepan Baturina, Monica Stephany Kirigin, Božo Krušlin

{"title":"Multiple Primary Angiosarcomas of the Colon.","authors":"Sonja Radić, Mario Zovak, Anita Galović Marić, Stjepan Baturina, Monica Stephany Kirigin, Božo Krušlin","doi":"10.1155/2021/7237379","DOIUrl":"https://doi.org/10.1155/2021/7237379","url":null,"abstract":"Introduction: Gastrointestinal angiosarcomas are rare and represent less than 1% of all gastrointestinal tract malignancies, with most occurring in the stomach and small intestine. Occurrence in the colorectal segments is considered extremely rare. Case Report. We describe the case of a 61-year-old male with multiple primary angiosarcomas of the colon who presented with fever and abdominal pain. The patient was initially hospitalized and treated as having an infectious disease. A multislice computed tomography (MSCT) scan revealed multiple soft tissue tumors in the region of the left iliopsoas and gluteus medius muscles. After developing hematochezia, a colonoscopy was performed which found an ulcerated tumor in the sigmoid colon. The small tissue biopsy taken during the procedure presented diagnostic difficulties and was given a preliminary diagnosis of gastrointestinal stromal tumor (GIST). Examination of the resected colon segment and surrounding fat tissue revealed four separate tumors. Microscopically, the tumors were composed of solid sheets of spindle and epithelioid neoplastic cells with prominent nucleoli and numerous mitotic figures and immunohistochemically positive for ERG, CD31, CD34, vimentin, and CD117, while negative for CK7, CK20, CD20, CD3, CD45, TTF-1, PAN-CK, ALK, Mpox, S-100, and DOG1, leading to the final diagnosis of multiple colonic angiosarcomas. The patient's condition declined rapidly and he passed away from multiple organ failures 60 days after initial hospitalization.Conclusion: Both clinical and pathological diagnoses of colorectal angiosarcoma are challenging. Patients are present with nonspecific symptoms leading to mismanagement and late diagnosis. A definitive pathological diagnosis relies on immunohistochemical staining for endothelial markers. Misdiagnosis as poorly differentiated adenocarcinoma or GIST is possible in limited tissue biopsies.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2021-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39434602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Primary Dural Lymphoma Mimicking En Plaque Cerebellopontine Angle Meningioma. 原发性硬脑膜淋巴瘤模拟En斑块脑桥小脑角脑膜瘤。

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Case Reports in Pathology Pub Date : 2021-07-23 eCollection Date: 2021-01-01 DOI: 10.1155/2021/2845995

Mei Xu, Ashish Bains, Yuan Rong

{"title":"Primary Dural Lymphoma Mimicking En Plaque Cerebellopontine Angle Meningioma.","authors":"Mei Xu, Ashish Bains, Yuan Rong","doi":"10.1155/2021/2845995","DOIUrl":"https://doi.org/10.1155/2021/2845995","url":null,"abstract":"Primary dural lymphoma (PDL) usually arises from the calvarial dura without the brain parenchyma or systemic involvement and thus may not be considered as a typical form of primary CNS lymphoma (PCNSL). It is exceedingly rare. When it occurs, it might not be suspected as a primary diagnosis on clinical and radiologic findings. We present a PDL case that occurs at the cerebellopontine (CP) angle mimicking en plaque meningioma. The tumor histopathology showed a lymphoproliferative disorder immunophenotypically consistent with a low-grade marginal zone lymphoma. Bone marrow and systemic involvements were not identified, and a diagnosis of PDL was established. As a residual tumor at the CP angle was inaccessible to surgery, postoperative radiation therapy was performed. No recurrence was found at 15-month follow-up. PDLs are mostly indolent and have a good prognosis. There is no doubt that the most important differential diagnosis is meningioma. Furthermore, the present case emphasizes the necessity of an intraoperative consultation and knowledge of this rare yet essential form of PCNSL so that appropriate studies can be ordered.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2021-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39269473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Metastatic Seminoma with Positive Staining of Cytokeratin and MOC31: A Diagnostic Pitfall. 细胞角蛋白和MOC31染色阳性的转移性精原细胞瘤:一个诊断缺陷。

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Case Reports in Pathology Pub Date : 2021-06-29 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9992978

Jiaming Fan, Ren Yuan, David Stefanelli, Gang Wang

引用次数: 1

Corrigendum to "Localized Biphasic Malignant Peritoneal Mesothelioma with Rhabdoid Features Involving the Liver: Case Report and Review of the Literature". “局部双期恶性腹膜间皮瘤伴横纹肌样特征累及肝脏:病例报告及文献回顾”的更正。

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Case Reports in Pathology Pub Date : 2021-06-15 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9867879

Dalal Hassan, Saverio Ligato

引用次数: 0

A Rare Case of a Solitary Fibrous Tumor of the Spermatic Cord. 精索单发纤维性肿瘤1例。

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Case Reports in Pathology Pub Date : 2021-05-22 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9956305

Moyosore Awobajo, Stefanie Hettwer, Sarah Hackman

引用次数: 2

Leiomyosarcoma of the Renal Vein Mimicking a Primitive Renal Cell Carcinoma: Case Report of an Unusual Presentation. 模拟原始肾细胞癌的肾静脉平滑肌肉瘤:一个不寻常的表现报告。

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Case Reports in Pathology Pub Date : 2021-05-12 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6637533

Amal Fekkar, Hafsa Elouazzani, Ahmed Jahid, Kaoutar Znati, Fouad Zouaidia, Zakia Bernoussi

引用次数: 1

A Rare Case of Endometriosis of the Small Bowel. 一例罕见的小肠子宫内膜异位症。

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Case Reports in Pathology Pub Date : 2021-05-08 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6676855

Moisés R Zepeda, Su K Win

引用次数: 1

A Review Leveraging a Rare and Unusual Case of Basal Cell Carcinoma of the Prostate. 回顾一例罕见的前列腺基底细胞癌。

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Case Reports in Pathology Pub Date : 2021-05-04 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5520581

Lin He, Christopher Metter, Vitaly Margulis, Payal Kapur

引用次数: 5

Colonic Metastasis of Adenoid Cystic Carcinoma 19 Years after the Primary Tumor Resection. 腺样囊性癌原发肿瘤切除后19年的结肠转移。

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Case Reports in Pathology Pub Date : 2021-04-27 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5511935

Subramanya Sakaleshpura Mallikarjunappa, Shriram Jakate, Lin Cheng

引用次数: 1