Case Reports in Pathology最新文献_第7页

A Rare Case of Endometriosis of the Small Bowel. 一例罕见的小肠子宫内膜异位症。

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Case Reports in Pathology Pub Date : 2021-05-08 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6676855

Moisés R Zepeda, Su K Win

引用次数: 1

A Review Leveraging a Rare and Unusual Case of Basal Cell Carcinoma of the Prostate. 回顾一例罕见的前列腺基底细胞癌。

IF 0.6

Case Reports in Pathology Pub Date : 2021-05-04 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5520581

Lin He, Christopher Metter, Vitaly Margulis, Payal Kapur

引用次数: 5

Colonic Metastasis of Adenoid Cystic Carcinoma 19 Years after the Primary Tumor Resection. 腺样囊性癌原发肿瘤切除后19年的结肠转移。

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Case Reports in Pathology Pub Date : 2021-04-27 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5511935

Subramanya Sakaleshpura Mallikarjunappa, Shriram Jakate, Lin Cheng

引用次数: 1

Dysgerminoma with Estrogen-Producing Functioning Stroma Presenting Precocious Puberty. 伴有雌激素分泌功能基质的生殖细胞异常瘤表现为性早熟。

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Case Reports in Pathology Pub Date : 2021-04-22 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5545645

Shunsuke Nagase, Kanako Ogura, Karin Ashizawa, Nana Nakazawa-Tanaka, Masahiko Urao, Masaharu Fukunaga, Yuto Yamazaki, Hironobu Sasano, Toshiharu Matsumoto

{"title":"Dysgerminoma with Estrogen-Producing Functioning Stroma Presenting Precocious Puberty.","authors":"Shunsuke Nagase, Kanako Ogura, Karin Ashizawa, Nana Nakazawa-Tanaka, Masahiko Urao, Masaharu Fukunaga, Yuto Yamazaki, Hironobu Sasano, Toshiharu Matsumoto","doi":"10.1155/2021/5545645","DOIUrl":"https://doi.org/10.1155/2021/5545645","url":null,"abstract":"Dysgerminoma is a malignant ovarian germ cell tumor, and unlike sex-cord stromal tumors, endocrine manifestation is considered rare. Here, we report the first case of dysgerminoma presenting precocious puberty. The patient is a 7-year-old girl who presented with a breast development in Tanner stage 3. Serum estradiol (E2) was markedly elevated while luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were suppressed below the detection limit. Microscopically, the right ovarian mass displayed nests of large polygonal cells and fibrous septa which were focally concentrated by theca-like plump spindle cells. Immunohistochemistry revealed that the spindle cells expressed various steroidogenic enzymes involved in estrogen biosynthesis including P450 aromatase. The tumor was diagnosed with pure dysgerminoma with estrogen-producing functioning stroma. After the operation, serum E2 declined below the detection limit; LH and FSH returned within the normal range. This case demonstrates that even a conventional dysgerminoma can present endocrine manifestation through functioning stroma.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"2021 ","pages":"5545645"},"PeriodicalIF":0.6,"publicationDate":"2021-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39049436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Two Synchronous Neonatal Tumors: An Extremely Rare Case. 两个新生儿同步肿瘤:一例极为罕见的病例。

IF 0.6

Case Reports in Pathology Pub Date : 2021-04-19 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6674372

M Rodríguez-Zubieta, K Albarenque, C Lagues, A San Roman, M Varela, D Russo, G Podesta, D Steinberg, C Schauvinhold, A Etchegaray, M T G de Dávila

{"title":"Two Synchronous Neonatal Tumors: An Extremely Rare Case.","authors":"M Rodríguez-Zubieta, K Albarenque, C Lagues, A San Roman, M Varela, D Russo, G Podesta, D Steinberg, C Schauvinhold, A Etchegaray, M T G de Dávila","doi":"10.1155/2021/6674372","DOIUrl":"https://doi.org/10.1155/2021/6674372","url":null,"abstract":"We report a case of a newborn with two synchronous tumors-sialoblastoma and hepatoblastoma-diagnosed at 20 weeks of gestation by magnetic resonance imaging (MRI) and ultrasonography (US). The aim of this study was to describe the management of this case together with a review of the literature. Our patient had a large facial tumor associated with extremely high alpha-fetoprotein levels. Diagnosis of the tumors was made by surgical biopsy, showing typical features in both. Sialoblastoma is a potentially aggressive tumor. In our case, the Ki67 index in the sialoblastoma was between 20 and 30%, indicating a possibly unfavorable behavior. The infant underwent surgery and chemotherapy in different steps. Complete surgical resection with clean margins is considered to be the best treatment option for sialoblastoma. Only four similar cases were previously reported. Timely management by a multidisciplinary team is essential in these difficult cases. In our patient, outcome was good at the time of this report.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"2021 ","pages":"6674372"},"PeriodicalIF":0.6,"publicationDate":"2021-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38889435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Pulmonary Alveolar Microlithiasis: A Unique Case of Familial PAM Complicated by Transplant Rejection. 肺泡微石症:家族性PAM合并移植排斥的独特病例。

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Case Reports in Pathology Pub Date : 2021-04-05 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6674173

Austin Helmink, Samir Atiya, Ernesto Martinez Duarte

引用次数: 2

Leydig Cell Tumor in a Patient with 46,XX Disorder of Sex Development (DSD), Ovotesticular: A Case Report and a Review of the Literature. 46,XX性发育障碍(DSD)患者卵睾丸间质细胞瘤1例并文献复习。

IF 0.6

Case Reports in Pathology Pub Date : 2021-03-29 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5552305

Steffen Gretser, Maria-Noemi Welte, Frederik Roos, Jens Köllermann

{"title":"Leydig Cell Tumor in a Patient with 46,XX Disorder of Sex Development (DSD), Ovotesticular: A Case Report and a Review of the Literature.","authors":"Steffen Gretser, Maria-Noemi Welte, Frederik Roos, Jens Köllermann","doi":"10.1155/2021/5552305","DOIUrl":"https://doi.org/10.1155/2021/5552305","url":null,"abstract":"Disorder of sex development (DSD) is a rare condition with atypical development of chromosomal, gonadal, or anatomical sex. It is classified in different subgroups based on the patient's karyotype, gonadal dysgenesis, and the appearance of the internal and external genitalia. Within the subgroups, the risk for developing neoplasms varies a lot. Here, we report the case of a 41-year-old patient with disorder of sex development, showing a 46,XX karyotype with an ovotestis and the simultaneous manifestation of a Leydig cell tumor in the ovotestis. The patient initially presented with infertility, and a suspicious lesion of the left testicle was noted on MRI-Scan. Upon resection, a Leydig cell tumor and an ovotestis were diagnosed. Nongerm call tumors are rare in patients with DSD. We report a nongerm cell tumor in a patient with 46,XX DSD, ovotesticular. This shows that although 46,XX DSD, ovotesticular is known to have a low potential for germ cell neoplasia, nongerm cell tumors can develop and should be into account for the management of those patients.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"2021 ","pages":"5552305"},"PeriodicalIF":0.6,"publicationDate":"2021-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38883917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Malignant Glandular Triton Tumor Arising in the Radial Nerve with Prolonged Survival: A Case Report and Review of the Literature. 发生于桡神经并延长生存期的恶性腺状Triton肿瘤1例报告及文献复习。

IF 0.6

Case Reports in Pathology Pub Date : 2021-03-18 eCollection Date: 2021-01-01 DOI: 10.1155/2021/4614185

Batool M AlAli, Samir S Amr

{"title":"Malignant Glandular Triton Tumor Arising in the Radial Nerve with Prolonged Survival: A Case Report and Review of the Literature.","authors":"Batool M AlAli, Samir S Amr","doi":"10.1155/2021/4614185","DOIUrl":"https://doi.org/10.1155/2021/4614185","url":null,"abstract":"Divergent differentiation is a well-known phenomenon in malignant peripheral nerve sheath tumors (MPNST) which occurs approximately in 15% of these tumors, usually towards mesenchymal elements. Differentiation towards epithelial components, however, is quite uncommon, and even exceptionally rare is concomitant mesenchymal and glandular differentiation. To our knowledge, only 14 cases of MPNST with both mesenchymal (rhabdomyoblastic) and glandular differentiation had been reported, and only two of these tumors had frankly malignant glandular components. Herein, we report the third such case. A 26-year-old male, without any of the stigmata of NF1, presented with a 2-year history of pain in his left shoulder and an elbow swelling of six-month duration. The tumor was initially diagnosed clinically as a neurofibroma at a local hospital. The patient underwent excision of the mass there, and pathological examination at that hospital showed the tumor to be MPNST. Six months later, the patient was referred to our hospital, a tertiary care medical center, with recurrent swelling at the same location. Histopathological material from the referral hospital was reviewed, and the tumor was diagnosed as MPNST with rhabdomyoblastic differentiation or malignant triton tumor (MTT) that contained in addition foci of malignant glandular epithelium. The patient refused any surgical intervention. He received three cycles of chemotherapy followed by radiotherapy with excellent response and marked reduction in the size of the tumor. The patient had prolonged survival for 10 years following the initial resection of the tumor.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"2021 ","pages":"4614185"},"PeriodicalIF":0.6,"publicationDate":"2021-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25537573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Case of Follicular Tumor of Uncertain Malignant Potential (FT-UMP) with Glomeruloid Features Showing Capsular Mucinous Degeneration. 恶性潜能不确定的滤泡性肿瘤(FT-UMP) 1例，肾小球特征表现为囊状粘液变性。

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Case Reports in Pathology Pub Date : 2021-03-11 eCollection Date: 2021-01-01 DOI: 10.1155/2021/1686025

Daniela Cabibi, Andrea Mondello, Ada Maria Florena, Giulia Rimi, Antonino Giulio Giannone, Calogero Cipolla, Maria Rosaria Valerio, Giuseppa Graceffa

引用次数: 1

Atypical Nodular Pulmonary Kappa Light-Chain Deposition. 非典型结节性肺Kappa轻链沉积。

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Case Reports in Pathology Pub Date : 2021-03-10 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5578885

Jessy Nellipudi, John Brealey, Sonja Klebe, David Lance

引用次数: 0