Current Clinical Microbiology Reports最新文献_第2页

Gut Microbiota Resilience Mechanisms Against Pathogen Infection and its Role in Inflammatory Bowel Disease 肠道微生物群抗病原体感染的恢复机制及其在炎症性肠病中的作用

Current Clinical Microbiology Reports Pub Date : 2023-10-07 DOI: 10.1007/s40588-023-00207-4

Marcella Cipelli, Eloísa Martins da Silva, Niels Olsen Saraiva Câmara

引用次数: 0

Symbiotic Interactions of Archaea in Animal and Human Microbiomes 古生菌在动物和人类微生物群中的共生相互作用

Current Clinical Microbiology Reports Pub Date : 2023-09-29 DOI: 10.1007/s40588-023-00204-7

Nancy Weiland-Bräuer

{"title":"Symbiotic Interactions of Archaea in Animal and Human Microbiomes","authors":"Nancy Weiland-Bräuer","doi":"10.1007/s40588-023-00204-7","DOIUrl":"https://doi.org/10.1007/s40588-023-00204-7","url":null,"abstract":"Abstract Purpose of Review Since the introduction of Archaea as a new domain of life more than 45 years ago, progress in their phylogenetic classification and knowledge of their exclusive biological characteristics has identified archaea as unique microorganisms which are widespread in extreme but also in various moderate ecosystems, including eukaryotic hosts. However, archaea are still neglected players within microbiomes, and research on archaea-bacteria interactions is still in its infancy due to methodological challenges. Recent Findings This review summarizes the current knowledge of archaea as components within microbiomes and focuses on their interactions with their bacterial neighbors and the principles of archaeal interactions. Summary Archaea are common constituents of animal and human microbiomes, which are dominated by Euryarchaeota. The gastrointestinal tract is the most studied body site, where archaea account for up to 4% of all microorganisms, primarily represented by methanogens. No archaeal pathogen has yet been identified, although methanogens are hypothesized to be indirectly involved in pathogenicity. Archaeal interactions comprise symbiotic relationships, and the cell membrane and wall might be as crucial as quorum sensing/quenching for these interactions. Particularly, syntrophic interactions under energy-deficiency stress seem to be an essential strategy for archaea. However, more research is urgently needed to discover how archaea sense their environment, compete with bacteria, and interact within complex microbiomes associated with multicellular organisms.","PeriodicalId":45506,"journal":{"name":"Current Clinical Microbiology Reports","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135133102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insight into the Physiological and Molecular Crosstalk During Bacterial-Fungal Interactions 细菌-真菌相互作用中生理和分子串扰的深入研究

Current Clinical Microbiology Reports Pub Date : 2023-09-29 DOI: 10.1007/s40588-023-00206-5

Dibya Jyoti Hazarika, Merilin Kakoti, Tanushree Borgohain, Alokesh Ghosh, Robin Chandra Boro

引用次数: 0

The Application Potential of Synthetic Biology in Microbial Communication 合成生物学在微生物传播中的应用潜力

Current Clinical Microbiology Reports Pub Date : 2023-09-21 DOI: 10.1007/s40588-023-00205-6

Yan Wang, Jin Zhou

引用次数: 0

Molecular Mechanisms of Severe Diseases Caused by Epstein-Barr Virus Infection eb病毒感染导致严重疾病的分子机制

Current Clinical Microbiology Reports Pub Date : 2023-09-13 DOI: 10.1007/s40588-023-00203-8

Jun-ichi Kawada

引用次数: 0

Modeling and Remodeling the Cell: How Digital Twins and HCMV Can Elucidate the Complex Interactions of Viral Latency, Epigenetic Regulation, and Immune Responses. 细胞建模和重塑：数字双胞胎和HCMV如何阐明病毒潜伏性、表观遗传学调节和免疫反应的复杂相互作用

IF 3.1

Current Clinical Microbiology Reports Pub Date : 2023-09-01 Epub Date: 2023-07-29 DOI: 10.1007/s40588-023-00201-w

Hana McMahon-Cole, Alicia Johnson, Sara Sadat Aghamiri, Tomáš Helikar, Lindsey B Crawford

{"title":"Modeling and Remodeling the Cell: How Digital Twins and HCMV Can Elucidate the Complex Interactions of Viral Latency, Epigenetic Regulation, and Immune Responses.","authors":"Hana McMahon-Cole, Alicia Johnson, Sara Sadat Aghamiri, Tomáš Helikar, Lindsey B Crawford","doi":"10.1007/s40588-023-00201-w","DOIUrl":"10.1007/s40588-023-00201-w","url":null,"abstract":"Purpose of review: Human cytomegalovirus (HCMV), while asymptomatic in most, causes significant complications during fetal development, following transplant or in immunosuppressed individuals. The host-virus interactions regulating viral latency and reactivation and viral control of the cellular environment (immune regulation, differentiation, epigenetics) are highly complex. Understanding these processes is essential to controlling infection and can be leveraged as a novel approach for understanding basic cell biology.Recent findings: Immune digital twins (IDTs) are digital simulations integrating knowledge of human immunology, physiology, and patient-specific clinical data to predict individualized immune responses and targeted treatments. Recent studies used IDTs to elucidate mechanisms of T cells, dendritic cells, and epigenetic control-all key to HCMV biology.Summary: Here, we discuss how leveraging the unique biology of HCMV and IDTs will clarify immune response dynamics, host-virus interactions, and viral latency and reactivation and serve as a powerful IDT-validation platform for individualized and holistic health management.","PeriodicalId":45506,"journal":{"name":"Current Clinical Microbiology Reports","volume":"10 1","pages":"141-151"},"PeriodicalIF":3.1,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44737884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contagion Went Viral: Microbiology, Entertainment Media and the Public Understanding of Science 传染病变成病毒：微生物学、娱乐媒体和公众对科学的理解

IF 5.2

Current Clinical Microbiology Reports Pub Date : 2023-08-02 DOI: 10.1007/s40588-023-00196-4

Amy C. Chambers

引用次数: 0

Severe Disease in Children with Parechovirus-A Infection 儿童感染parechov - a的严重疾病

IF 5.2

Current Clinical Microbiology Reports Pub Date : 2023-07-19 DOI: 10.1007/s40588-023-00197-3

Jun Tachikawa, Y. Aizawa, A. Saitoh

引用次数: 0

Eliminating Candida auris: Between Ultraviolet-C Radiations and Medicinal Plants, Which One Is Better? 消除耳念珠菌:在紫外线c辐射和药用植物之间，哪个更好?

IF 5.2

Current Clinical Microbiology Reports Pub Date : 2023-06-28 DOI: 10.1007/s40588-023-00200-x

K. Nwachukwu, O. Ugbogu, E. Nwarunma, C. Nwankpa

引用次数: 0

The Role of the Oxidative Stress-Inflammation Axis in the COVID-19-Infected Patients with Chagas Disease: A Key Parameter To Be Considered During the Pandemic 氧化应激-炎症轴在covid -19感染恰加斯病患者中的作用:大流行期间需要考虑的关键参数

IF 5.2

Current Clinical Microbiology Reports Pub Date : 2023-06-24 DOI: 10.1007/s40588-023-00198-2

D. Aydemir, N. N. Ulusu

引用次数: 0