International Journal of Burns and Trauma最新文献

{"title":"The role of keratinocyte function on the defected diabetic wound healing.","authors":"Navid Hosseini Mansoub","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Non-healing wounds are a major complication of diabetes that can lead to limb amputation and disability in patients. The normal process of wound repair progresses through well-defined stages including hemostasis, inflammation, proliferative, and remodeling, which may be impaired in diabetic wounds. In recent years, it has been reported that keratinocytes, a major cell type in human skin, play a key role in the healing process of wounds. In this overview, firstly, a summary of the wound healing process is provided and the role of keratinocytes in wound healing is briefly reviewed. Then, a set of evidence about the impaired keratinocytes activities in diabetic wounds and clinical trials focused mainly on improving keratinocytes in the context of diabetic wound therapeutics are summarized. Keratinocytes can produce signaling molecules that act in a paracrine and autocrine way, causing pleiotropic effects on various cell types. The affected cells respond to keratinocytes by creating several signaling molecules, which also adjust keratinocyte activation through wound healing. In diabetic wounds, disruption of various biological mechanisms leads to dysfunction of keratinocytes including impaired migration, adhesion, and proliferation. The function of abnormal keratinocytes can lead to poor diabetic wound healing. Taken together, clarification of molecular and functional disturbances of keratinocyte cells and applying them in diabetic wounds can contribute to enhanced treatment of diabetic wounds. Based on the location of keratinocytes in the epidermis and the central role of keratinocytes in the diabetic wound healing process, applying keratinocytes has great potential for the treatment of diabetic burn wounds.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784740/pdf/ijbt0011-0430.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39580406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of contemplating patient care spiritual flow principles and mindfulness on trauma center nurses' wellbeing: a pilot trial.","authors":"Carl M Dunham,&nbsp;Amanda J Burger,&nbsp;Barbara M Hileman,&nbsp;Elisha A Chance,&nbsp;Paul Lisko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Trauma nurses commonly encounter stress and burnout and have increased negative affect states and decreased positive affect traits. This study investigated whether trauma center nurses would have improvements in wellbeing scores after reading and contemplating <i>Spiritual Flow: Pathways to Proficient Patient Care and Nurse & Physician Wellbeing</i> (<i>Spiritual Flow</i>). Trauma center surgical intensive care unit nurses completed a baseline and follow-up survey before and after reading and contemplating <i>Spiritual Flow</i>, which provides insights into spirituality and mindfulness. The survey contained four positive affect (PA) items, each rated 1-very little to 5-extremely, that were summed to create a PA score (PAS). The seven negative affect (NA) survey items were similarly rated and reverse coded, 1-extremely to 5-very little, to create a nonstress score (NSS). The PAS (4-20) and NSS (7-35) were summed to create a wellbeing score (WS). Nurses rated the degree to which they felt more peaceful or inspired after contemplating the book. Thirty-seven of 39 (95%) routine nursing staff members completed both surveys. Follow-up values increased for WS (P = 0.0001) and NSS (P = 0.0001) after reading and contemplating <i>Spiritual Flow</i> compared to baseline values. No changes occurred for PAS (P = 0.1606). Because 16% of nurses had a high PAS on the baseline survey, further analyses were performed on the other 84%. Significantly increased values were noted on follow-up for PAS (P = 0.0171), NSS (P = 0.0015), and WS (P = 0.0003) compared to baseline scores. Of 37 nurses, 24 (64.9%) rated feeling more peaceful and/or inspired as moderately or quite a bit. This pilot study suggests that contemplating <i>Spiritual Flow</i> was associated with improvements in surgical intensive care trauma center nurse wellbeing. These preliminary findings need to be confirmed in an investigation that includes a control group and randomization.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784743/pdf/ijbt0011-0477.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39580413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the efficacy of Agicoat in the treatment of partial-thickness skin graft donor sites of burn patients.","authors":"Hossein Abdollahi Veshnavei","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Burns is the most common condition that requires extensive skin grafting. Treatment of burns is associated with long hospital stays, expensive medications, multiple surgeries, and long-term rehabilitation. Rapid healing of skin donor areas in partial-thickness burn wounds is important for the patient. Partial-thickness skin grafting is a technique that can reduce healing time and improve the treatment. Nanocrystalline silver contains antibacterial and anti-inflammatory properties. This study aimed to evaluate the efficacy of Agicoat in the treatment of partial-thickness skin graft donor sites of burn patients in terms of healing time, pain and scarring.</p><p><strong>Method: </strong>This clinical trial study was performed on 100 patients who burn and were referred to Imam Khomeini Hospital in Tehran from July to January 2020. Patients with second- and third-degree burns who had burned 10 to 30 percent of their body surface and required partial-thickness skin graft surgery, were considered for this study. Each patient was compared to herself. The skin donor site was then randomly divided into three parts A, B and C and each part was dressed with Agicoat^TM, Mepitel and Vaseline gauze. On days 4 and 8, the amount of pain when changing the dressing was recorded based on visual analog scale (VAS). After six months, the patients were evaluated and compared for the scarring site based on Vancouver Scar Scale (VSS).</p><p><strong>Result: </strong>Comparison of the average healing time between groups showed that the average healing time in both groups was significantly shorter than the Vaseline group (P=0.005). Comparison of wound pain between groups on Day 4 showed that the mean pain in the Agicoat group and also the Mepitel group was significantly lower than the Vaseline group (P=0.004). However, Agicoat and Mepitel groups did not show a significant difference. Also, a comparison of pain between groups on Day 8 and the mean VAS six months after skin graft showed no difference between groups.</p><p><strong>Conclusion: </strong>According to the findings of this study, if the Agicoat dressing is cost-effective, it can be a good alternative to cover the wound of the skin donor site, and it heals faster and reduces pain.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784746/pdf/ijbt0011-0470.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39580411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of proximal femoral geometry and its relationship with body mass index in Iranian people: a cross sectional study.","authors":"Masoumeh Faghani,&nbsp;Payman Asadi,&nbsp;Seyyed Mahdi Zia Ziabari,&nbsp;Nazanin Noori Roodsari,&nbsp;Esmaiel Nourisa,&nbsp;Amirali Daryagasht","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>There are several studies on the angle of the femoral neck in different countries. It seems that data of diverse races might help the prediction of femoral neck fractures. The present study aimed to evaluate the femoral neck-shaft angle (FNSA) as a predictive factor of neck fracture in Iranian people.</p><p><strong>Methods: </strong>In this cross-sectional study, the FNSA was measured using radiographs in 635 patients referred to Poursina Hospital in Rasht from September 2018 to October 2019. The body mass index (BMI) was calculated, age and sex of patients were recorded. Data were analyzed by SPSS. The level of statistical significance was adjusted to P<0.05.</p><p><strong>Results: </strong>According to the measured variables, gender, age, BMI and right FNSA are significant in the way that participants with normal BMI have higher FNSA. FNSA decreased with age and height. Obese people had lower FNSA than normal and overweight people. Comparison of left and right angles using the Wilcoxon test showed a statistically significant difference (P<0.001). The right side FNSA was more than the left (59.94%). Only in 39.9%, the left FNSA was more than the right, and in 0.15% both were the same.</p><p><strong>Conclusion: </strong>The present cross-sectional study shows a significant relationship between BMI and FNSA. It is suggested that physician evaluates these parameters for prediction of fracture risk in individuals.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784741/pdf/ijbt0011-0463.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39580410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of pilon fractures with low profile plates.","authors":"Ali Andalib,&nbsp;Mohammad Reza Etemadifar,&nbsp;Aryan Rafiee Zadeh,&nbsp;Pouya Moshkdar","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Treatments of pilon fracture is an important operative challenge due to high prevalence of post-operative complications. In this paper, we aimed to evaluate the complications of the use of low profile plates for pilon fractures.</p><p><strong>Methods: </strong>This clinical trial that was performed in 2017-2021 in Isfahan on 27 patients with pilon fractures. Demographic data of patients such as age, gender, type of pilon fracture and baseline pathology of pilon fractures were collected. Patients were treated using low profile plates under surgical procedures. Within 1 month, 3 months and 6 months after surgeries, patients were visited and assessed regarding superficial wound infections, deep wound infections, and evidence of osteomyelitis, vascular injuries, non-union and mal-union using both physical examinations and imaging studies via X-ray. We also measured the functions of cases using The American Orthopedic Foot and Ankle Score (AOFAS) questionnaire.</p><p><strong>Results: </strong>Most cases had 3 days (33.3%) and 5 days (33.3%) of hospitalization. Superficial wound infection was observed in 7 cases (26%). Deep surgical site infections were observed in 2 cases (7.4%) and we had only 1 case of osteomyelitis (3.7%). No vascular injuries were observed in this study. Evaluation of union among patients showed that 2 cases (7.4%) had non-union and 5 cases (18.5%) had malunion in the anterior-posterior axis, but none of the patients had malunion in the coronal axis. Based on AOFAS questionnaire, the mean score in patients was 88.36±14.20.</p><p><strong>Conclusion: </strong>Treatments of pilon fractures by low profile plates have similar complications compared to other treatment options.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784745/pdf/ijbt0011-0486.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39580412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cemented unipolar or modular bipolar hemiarthroplasty for femoral neck fractures in elderly patients - which is better?","authors":"Abdul Q Khan,&nbsp;Julfiqar Mohammad,&nbsp;Rayed Qamar,&nbsp;Yasir S Siddiqui,&nbsp;Aamir B Sabir,&nbsp;Mazhar Abbas","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Hemiarthroplasty is considered to be the treatment of choice for femoral neck fractures in elderly, however there is no consensus to support the choice between unipolar or bipolar hemiarthroplasty. Several studies found that patients with bipolar hemiarthroplasty had a better outcome of pain, a higher rate of return to the pre-injury state, and a greater range of hip motion. Some studies have demonstrated equal hip functional outcome between unipolar and bipolar hemiarthroplasty, but unipolar hemiarthroplasty was favoured due to its lower cost. The purpose of this study was to compare the functional and radiological outcome of cemented unipolar vs modular bipolar hemiarthroplasty in displaced femoral neck fracture in elderly patient population.</p><p><strong>Methods: </strong>It is a prospective randomized study, with 44 patients in each group. Elderly Patients (>60 years of age) with traumatic displaced femoral neck fractures were included in the study. Cemented unipolar or modular bipolar hemiarthroplasty was performed in the respective patient groups using posterior or anterolateral approach. Functional outcome evaluation was done by Harris Hip Score and radiological outcome evaluation was done for acetabular erosion. The data was entered in MS EXCEL spread sheet and analysis was done using Statistical Package for Social Sciences (SPSS) version 20.0 (IBM, Chicago).</p><p><strong>Results: </strong>The mean age in the unipolar and bipolar group was 67.2 and 66.1 years respectively. The average follow-up period was 20.1 and 22.3 months in the unipolar and bipolar group respectively. Mean operating time was significantly more in the modular bipolar group (78.3 minutes) compared to the unipolar group (67.3 minutes). Two patients (4.5%) had acetabular erosion in each group. Mean Harris Hip score at 3 months follow-up was significantly higher (<i>p</i> value <0.05) in bipolar group (75.8±4.2) than the unipolar group (77.7±2.9). However, subsequent follow-ups at 6 months (80.9±2.8, 82.0±2.5, <i>p</i> value >0.05) 12 months (83.1±2.2, 83.2±1.2, <i>p</i> value >0.05) and 24 months (85.5±2.4, 85.2±2.8, <i>p</i> value >0.05) did not show any significant difference between the two groups. The incidence of general complications was 34% in bipolar and 20.4% in unipolar hemiarthroplasty group.</p><p><strong>Conclusion: </strong>Functional outcome in terms of Harris Hip Score are better in the bipolar group at 3 months follow up but there was no significant difference in the functional outcome between the two groups at 6, 12 and 24 months follow up. The operative time for unipolar is lower and statistically significant compared to bipolar hemiarthroplasty of the hip.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784747/pdf/ijbt0011-0447.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39580408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress of scar repair and its influence on physical and mental health.","authors":"Wenke Shen,&nbsp;Liang Chen,&nbsp;Fubo Tian","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A scar is a normal and an inevitable physiological response to the natural healing process of wounds or trauma in the human body. The essence of scar is a kind of abnormal and unsound tissue that does not possess the structure, physiological function and vitality of normal skin tissue. Scars not only affect the beauty of the body surface, but also impede the physiological function of the related tissues and organs, and even lead to deformities. Therefore, scar repair is of great significance to patients' appearance, physiological function as well as physical and mental health. Currently, the main approaches for scar repair in clinic are photorejuvenation or fruit acids. The purpose of this study is to investigate the current research progress of scar repair and the impact of scar repair on the physical and mental health of patients.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784744/pdf/ijbt0011-0442.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39580407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified cerclage wiring in comminuted transolecranon fracture-dislocations of the elbow.","authors":"Praveen Sodavarapu,&nbsp;Deepak Kumar,&nbsp;Shahnawaz Khan,&nbsp;Karmesh Kumar,&nbsp;Aman Hooda,&nbsp;Aditya Vardhan Guduru","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Transolecranon fracture-dislocations are a result of high-energy trauma, caused due to axial loading of the flexed forearm, with associated anterior dislocation of the ulna with respect to the distal humerus. The usual management of these comminuted and unstable fractures is by using locking compression plates via the dorsal approach. However, plating in cases of poor soft tissue coverage and open wounds can be precarious. In this study, we aimed to evaluate outcomes of cerclage wiring in the management of comminuted trans-olecranon fracture-dislocations in such scenario. A total of seven patients diagnosed with trans-olecranon fracture-dislocation with poor soft tissue coverage who underwent cerclage wiring were included in the study. The aim was to realign the proximal portion of the olecranon to the trochlea and restore the normal ulnohumeral articular relationships accomplished by the anatomical reconstruction of the greater sigmoid notch. Reconstruction of the proximal ulna was started from the distal to the proximal direction so as to convert an unstable fracture into a stable one. After the reduction of the proximal fragment, two long 2 mm K wires were inserted from the tip of the olecranon into the intramedullary canal (with at least 1 wire passed subchondrally), and later cerclage was done. Postoperatively the patient was immobilized for a duration of two weeks and was later started on active assisted mobilization of the elbow. All patients showed fair-to-excellent outcome on the Mayo elbow performance score (MEPS) at the final follow-up (five patients had an excellent score, one had a good score, and one had a fair score). At the final follow-up, the mean extension, flexion, pronation and supination were -20, 117.14, 82.85 and 78.57 degrees respectively. The key components of such management are the restoration of articular congruity, including continuity of the sigmoid cavity, ulnar length, and early initiation of active elbow movements to avoid joint stiffness. Optimal functional results can be achieved with K wire and cerclage when a stable anatomic reconstruction is accomplished, as a feasible alternative to plating.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784742/pdf/ijbt0011-0456.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39580409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of therapeutic results of closed and open repair of mandibular condylar fractures.","authors":"Amir Tabatabaee,&nbsp;Amin Javanbakht,&nbsp;Meysam Mohammadi Khah,&nbsp;Mehrdad Shahsavari-Pour,&nbsp;Farnaz Dehabadi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Mandibular condylar fractures mostly result from traumatic accidents or strife. There is still dispute on the effectiveness of various therapeutic methods. Here we aimed to evaluate and compare the open or closed repair methods for mandibular condylar fractures.</p><p><strong>Methods: </strong>This is a clinical trial that was performed in 2015-2021 in Iran on all patients that referred to our medical centers with mandibular fractures due to traumatic events. Those cases with severe lateral dislocation of the mandibular condyles or severe dislocations of the fractured parts were assigned to the open surgical treatment group. The other patients were treated using Arch bar + intermaxillary fixation (IMF). The patient's abilities of mouth opening were assessed in centimeters within 1 month, 3 months, 6 months, 1 year and 2 years after the operations.</p><p><strong>Results: </strong>726 mandibular fractures were evaluated. Our data showed that 302 fractures (41.6%) were in the mandibular condyles. Of the 302 condylar fractures, 172 fractures (57.1%) occurred due to automobile accidents and 82 fractures (27.5%) occurred due to direct trauma. 203 patients (67.2%) underwent the close surgical procedures using maxillary and mandibular fixation using arch bar + IMF. 99 patients (32.8%) underwent open mandibular fixation operation and internal fixation (ORIF). Assessments of mouth opening showed significant improvements in this ability within the follow-up period in both groups (P<0.001 for both). Furthermore, we observed that patients treated by the open mandibular fixation procedure had significantly better results within the 6 months and 1 year after the procedures but after 2 years, no significant differences could be observed between groups.</p><p><strong>Conclusion: </strong>Both open and closed surgical approaches for condylar fractures are associated with significant improvements, however, patients that were treated with ORIF had better clinical results in the first year after the surgical procedures.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610819/pdf/ijbt0011-0385.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39687268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic importance of serum C-reactive protein and procalcitonin in sepsis after burn.","authors":"Ebral Yiğit,&nbsp;Yasemin Demir Yiğit","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>In this study, we investigated the usefulness of blood white blood cell (WBC), C-reactive protein (CRP) and Procalcitonin (PCT) levels with a clinical diagnosis of infection in patients with severe burns, with a bacterial culture (+) wound site, in patients with SIRS and sepsis.</p><p><strong>Materials and methods: </strong>In the study, 23 patients with (+) burn wound culture hospitalized in the intensive care unit of Gazi Yaşargil Training and Research Hospital Burn Center burn between January 2016 and January 2021 were analyzed. While five of these patients were showing symptoms of SIRS. Sepsis was observed in five patients.</p><p><strong>Results: </strong>From 23 patients, 18 (78.3%) were male, and 5 (21.7%) were female. The majority of our patients were lived in rural areas. The average age of patients was 1,061±17,273 years. The wound culture results of the 23 patients were (+), mostly due to <i>Staphylococcus aureus</i> in 21.7% (n=5) and <i>Staphylococcus epidermidis</i> in 21.7% (n=5). PCT and CRP results did not statistically differ in patients with sepsis, SIRS and (+) wound culture.</p><p><strong>Conclusion: </strong>The laboratory biomarkers WBC, CRP and PCT do not have a superior value in determining and monitoring infection processes in patients with serious burns.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2021-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610824/pdf/ijbt0011-0391.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39687269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}