Gynecology and Minimally Invasive Therapy-GMIT最新文献

{"title":"Regarding a Cornual Pregnancy after Salpingectomy for Isthmic Pregnancy.","authors":"Ibrahim A Abdelazim, Ainur Donayeva, Ainur Amanzholkyzy","doi":"10.4103/gmit.gmit_83_24","DOIUrl":"10.4103/gmit.gmit_83_24","url":null,"abstract":"","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"197-198"},"PeriodicalIF":1.4,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to Deal with Bladder Stones Associated with Exposed Intravesical Mesh.","authors":"Purim Ruanphoo, Jimmy Nomura, Tokumasa Hayashi, Shino Tokiwa, Mika Nagae, Divina Soliza, Antonette Pesebre, Albert Ayumba, Hisao Kaneko","doi":"10.4103/gmit.gmit_86_24","DOIUrl":"10.4103/gmit.gmit_86_24","url":null,"abstract":"<p><p>We present the management of seven patients who were diagnosed with bladder stone associated with exposed intravesical mesh after transvaginal mesh (TVM) surgery for pelvic organ prolapse. The TVM may be exposed inside the bladder which can result in urinary stone formation. Several treatment modalities have been proposed such as laser lithotripsy, transurethral resection, and open or laparoscopic resection of exposed mesh. However, the optimal route of treatment remains inconclusive. In our series, two cases were managed by transurethral resection and one of them had recurrence. Five cases were managed by laparoscopic resection and one of them had recurrence. Two recurrent cases underwent laparoscopic resection and then no recurrence occurred. No intraoperative or postoperative complications occurred. Although there is limited evidence, we recommend laparoscopic resection for the treatment of intravesical mesh exposure. Offering transurethral resection as an initial management of intravesical mesh exposure is possible with careful discussion about the recurrence rate.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 3","pages":"259-263"},"PeriodicalIF":1.7,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the Relationship between Endometrial Cancer and Liver Fibrosis-4 Score.","authors":"Sema Yilmaz Rakici, Omer Yayla, Hanife Zeynep Yilmaz, Sefik Metin","doi":"10.4103/gmit.gmit_19_24","DOIUrl":"10.4103/gmit.gmit_19_24","url":null,"abstract":"<p><strong>Objectives: </strong>We investigated the relationship between the degree of fibrosis and endometrial cancer (EC) by calculating the fibrosis-4 (FIB-4) score, a noninvasive marker for measuring the severity of liver fibrosis.</p><p><strong>Materials and methods: </strong>Liver function tests, platelet (PLT) values, abdominal ultrasonography (USG), and magnetic resonance imaging (MRI) reports were analyzed retrospectively before, after, and at diagnosis in patients with EC.</p><p><strong>Results: </strong>The study included 38 patients diagnosed with EC. The median FIB-4 score was calculated as 1.15 (minimum: 0.46-maximum: 3.72). When endometroid (type 1 EC) and nonendometroid (type 2 EC) were compared, the FIB-4 score was higher in type one patients (1.16 [0.46-3.72] and 1.01 [0.53-2.96], respectively). However, there was no significant difference between the two groups (<i>P</i> = 0.961). There was no significant difference between the groups in terms of aspartate aminotransferase, alanine aminotransferase, and PLT parameters before diagnosis, at the time of diagnosis, and after treatment. Gamma-glutamyl transferase (GGT) level was significantly higher in the type 1 group in the prediagnosis period (<i>P</i> = 0.016). In the posttreatment period, GGT was higher in the type 2 group (<i>P</i> = 0.020). For PLT level, there was a statistically significant difference between all three periods only in the type 1 group (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>FIB-4 score was higher in patients with type 1 EC, which is more associated with obesity and hormones. In addition, prediagnostic values of GGT and PLT were statistically significantly higher in the type 1 group. Our study needs further studies to support FIB-4 score and biochemical GGT and PLT as biochemical markers in patients with type 1 EC.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"118-124"},"PeriodicalIF":1.4,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Laparoscopy for Advanced Ovarian, Fallopian Tube, and Peritoneal Cancers: A Retrospective Study.","authors":"Jongmyung Park, Takashi Seike, Haruka Sugi, Hironobu Hori, Kanako Gondo, Atsumu Terada","doi":"10.4103/gmit.gmit_32_24","DOIUrl":"10.4103/gmit.gmit_32_24","url":null,"abstract":"<p><strong>Objectives: </strong>Despite advancements in the management of advanced ovarian, fallopian tube, and peritoneal cancers, there remains a need to explore safe and effective diagnostic techniques, particularly in cases where primary debulking surgery (PDS) is challenging. This retrospective study aimed to investigate the safety and availability of diagnostic laparoscopy for patients with advanced ovarian, fallopian tube, and peritoneal cancers.</p><p><strong>Materials and methods: </strong>We analyzed data from 36 patients who underwent diagnostic laparoscopy between September 2017 and March 2023. The surgical outcomes of diagnostic laparoscopy and initial treatment outcomes were investigated.</p><p><strong>Results: </strong>The median patient age was 65 years (range, 39-82 years), with majority diagnosed with high-grade serous carcinoma (HGSC). Perioperative complications were observed in 11% of patients. Neoadjuvant chemotherapy (NAC) was administered to 92% of patients, with PDS performed in two cases. Of the 33 patients who received NAC, 30 (90%) underwent interval debulking surgery, and 23 (77%) achieved complete resection. Two patients (clear-cell carcinoma and mucinous carcinoma) died of cancer before or during the initial chemotherapy. The median follow-up duration for all patients was 26.9 months. Median progression-free survival (PFS) was 19.7 months, and median overall survival was 65.5 months. In multivariate analysis, non-HGSC (hazard ratio: 3.20, 95% confidence interval [CI]: 1.07-9.61, <i>P</i> = 0.038) and homologous recombination proficiency (hazard ratio: 7.44, 95% CI: 1.39-39.9, <i>P</i> = 0.019) were risk factors for PFS.</p><p><strong>Conclusion: </strong>Diagnostic laparoscopy is useful for intraperitoneal observation and pretreatment diagnosis in advanced ovarian, fallopian tube, and peritoneal cancers. Despite tolerable perioperative complications, further research is warranted to optimize patient outcomes.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"125-131"},"PeriodicalIF":1.4,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Device Selection Contributes to Operative Time Reduction in Laparoscopic Sacrocolpopexy.","authors":"Kenji Kuroda, Koetsu Hamamoto, Kazuki Kawamura, Ayako Masunaga, Akio Horiguchi, Keiichi Ito","doi":"10.4103/gmit.gmit_155_23","DOIUrl":"10.4103/gmit.gmit_155_23","url":null,"abstract":"<p><strong>Objectives: </strong>The standard laparoscopic sacrocolpopexy (LSC) technique involves several suture fixation sites, which can prolong the operative time. This study aimed to investigate the extent to which the operative time could be shortened using devices such as tackers in sites where suture manipulation could be omitted.</p><p><strong>Materials and methods: </strong>The study enrolled 82 patients who underwent LSC at our hospital between May 2016 and May 2022. The median operative time was 3.2 h (1.78-6.5 h). Changes in symptoms before and after surgery were measured using several questionnaires and 60-min pad weight testing among patient groups based on the device used.</p><p><strong>Results: </strong>Among the preoperative factors, no factors were found to be significantly correlated with the operative time (≥3.2 h or <3.2 h). As intraoperative factors, significant associations were found between the number of tackers used on the posterior vaginal wall, anterior vaginal wall, and cervix (0-3 locations), whether a device was used in mesh retroperitonealization, whether the first needle used to fix the anterior longitudinal ligament was successful, whether adhesion dissection was performed, and the type of sealing device. Among these factors, the use of tackers on the posterior wall, anterior wall, and cervix and the use of a device in mesh retroperitonealization were significantly associated with the operative time.</p><p><strong>Conclusion: </strong>The use of easy-to-operate devices appeared to contribute to a shorter operative time in LSC.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"157-164"},"PeriodicalIF":1.4,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Cesarean Scar Ectopic Pregnancy with Hysteroscopic Resection.","authors":"Hoora Amuzegar, Fatemeh Davari Tanha, Firoozeh Akbari Asbagh, Mahbod Ebrahimi, Sareh Ezzati, Venus Hajialiakbar","doi":"10.4103/gmit.gmit_28_24","DOIUrl":"10.4103/gmit.gmit_28_24","url":null,"abstract":"<p><p>Cesarean scar pregnancy (CSP) is an ectopic that is located in the myometrium of a previous C-section of the scar. It is rare but threatening. The aim of this study was to introduce 10 cases of CSP treated with hysteroscopic resection. In the preoperative phase, the patients with beta-human chorionic gonadotropin (B-hCG) titers more than 10,000 were treated with methotrexate (MTX) to reduce B-hCG titers. Two patients did not receive MTX. All patients were treated with hysteroscopic resection except one patient, who underwent hysteroscopic resectoscopy due to a lack of reduction of B-hCG and due to unrepairable scar site of cesarean and uterine perforation eventuate hysterectomy. All patients had normal menstrual cycles as well as the negative β-hCG level after 2 months. Moreover, no recurrence was reported after 3 years. Low-invasive treatments such as hysteroscopic resection can be an important step to maintain fertility and the general health of patients.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"170-173"},"PeriodicalIF":1.4,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Jain Point for First Blind Trocar Insertion: Fellows' Perspective.","authors":"Nutan Jain, Vandana Jain, Divyanee Gulati, Sakshi Srivastava, Priyanka Sureddi, Bhumika Bansal, Sweta Sareen, Sonika Mann, Chetna Agarwal, Shalini Singh, Sri Lakshmi Prasanna Bayya","doi":"10.4103/gmit.gmit_58_24","DOIUrl":"10.4103/gmit.gmit_58_24","url":null,"abstract":"","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"105-108"},"PeriodicalIF":1.4,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The New Concepts from New Evidences.","authors":"Chyi-Long Lee","doi":"10.4103/gmit.GMIT-D-24-00064","DOIUrl":"10.4103/gmit.GMIT-D-24-00064","url":null,"abstract":"","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 1","pages":"1-2"},"PeriodicalIF":1.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vesicouterine Cutaneous Fistula Post-cesarean Section - A Case Report.","authors":"Seham M Abufraijeh, Seif Jankhout, Basil Al-Tah, Abdallah Daradkeh, Suhaib A Allauzy","doi":"10.4103/gmit.gmit_44_24","DOIUrl":"10.4103/gmit.gmit_44_24","url":null,"abstract":"<p><p>This case report presents the diagnosis and management of a 41-year-old woman who developed a vesicouterine cutaneous fistula after a cesarean section. She initially presented with pus discharge from the cesarean wound site, and later exhibited cyclical hematuria and fluid leakage from the skin incision, prompting further investigation. Diagnostic modalities, including computed tomography with contrast, confirmed the presence of a complex fistula involving the bladder, uterus, and skin. Conservative management with gonadotropin-releasing hormone therapy was attempted but discontinued due to worsening symptoms. Surgical intervention was performed successfully, leading to the resolution of symptoms. This case underscores the importance of prompt recognition and appropriate management of rare postcesarean complications, emphasizing adherence to anatomical principles.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 1","pages":"85-88"},"PeriodicalIF":1.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risks of Malignancy among 11,204 Patients with Endometrial Polyp: A Systematic Review and Meta-analysis.","authors":"Sarah Al-Rayes, Mariam Mohamed, Eva Suarthana, Hormoz Nassiri Kigloo, Jason Raina, Togas Tulandi","doi":"10.4103/gmit.GMIT-D-24-00056","DOIUrl":"10.4103/gmit.GMIT-D-24-00056","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate factors associated with malignancy in patients with endometrial polyps.</p><p><strong>Materials and methods: </strong>We conducted electronic database research on PubMed, MEDLINE, EMBASE, COCHRANE, and Google Scholar from inception for all studies on endometrial polyp. After removing duplicates, and title and abstract screening, we had a total of 121 articles and 151 others from screening the reference list. Inclusion criteria included peri and postmenopausal women > 45 years diagnosed histopathologically with endometrial polyp(s). We excluded women with a history of endometrial cancer or hysterectomy.</p><p><strong>Results: </strong>Twenty studies were analyzed. Of 11204 patients with endometrial polyp, 287 had malignant polyps (2.75%), 182 (1.8%) had concomitant endometrial hyperplasia with atypia, and 520 (5.2%) had hyperplasia without atypia within the polyp. Menopausal women had a higher risk of pre-malignancy/malignancy than non-menopausal women (OR 5.63 (95CI 3.87, 8.20, <i>I</i> ² = 0%, <i>P</i> < 0.001). Endometrial thickness on ultrasound in pre-malignancy/malignancy cases was significantly thicker than in the benign polyp (mean difference 4.2 mm, 95% CI 0.8 to 7.6 mm, <i>I</i> ² = 18%, <i>P</i> = 0.02). Women who used tamoxifen or hormone replacement therapy (HRT) had a lower likelihood of endometrial pre-malignancy/malignancy, while women with abnormal uterine bleeding (AUB) had a higher probability of pre-malignancy/malignancy. The odd ratio of having pre-malignancy/malignancy among those who used tamoxifen was 0.50 (95% CI 0.26-0.94: <i>I</i> ² 12%, <i>p</i> = 0.03).</p><p><strong>Conclusion: </strong>In women with endometrial polyp, menopausal age and thickened endometrium might increase the probability while tamoxifen or HRT use might lower the likelihood of endometrial pre-malignancy/malignancy; and the presence of AUB might signal endometrial pre-malignancy/malignancy.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 1","pages":"40-50"},"PeriodicalIF":1.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}