Gynecology and Minimally Invasive Therapy-GMIT最新文献

Juvenile Granulosa Cell Tumor of the Ovary in Pregnancy: A Case Report. 妊娠期卵巢幼年颗粒细胞瘤1例报告。

IF 1.7

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.4103/gmit.GMIT-D-24-00039

Kavita Khoiwal, Polaki Manisha, Prashant Durgapal, Shalini Bose, Rama Divya Reddy, Jaya Chaturvedi

引用次数: 0

Integration of Indocyanine Green Sentinel Lymph Node Mapping and Laparoscopic Uterosacral Nerve Ablation: Advancements in Minimally Invasive Gynecologic Surgery. 吲哚菁绿前哨淋巴结定位与腹腔镜子宫骶神经消融的整合：微创妇科手术的进展。

IF 1.7

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.4103/gmit.GMIT-D-25-00060

Chyi-Long Lee

引用次数: 0

Clinical Implications of Extracellular Vesicles in Endometriosis: A Systematic Review. 子宫内膜异位症细胞外囊泡的临床意义：系统综述。

IF 1.7

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.4103/gmit.GMIT-D-24-00062

Marcelina Sztyler-Krąkowska, Agnieszka Wąsowicz

{"title":"Clinical Implications of Extracellular Vesicles in Endometriosis: A Systematic Review.","authors":"Marcelina Sztyler-Krąkowska, Agnieszka Wąsowicz","doi":"10.4103/gmit.GMIT-D-24-00062","DOIUrl":"10.4103/gmit.GMIT-D-24-00062","url":null,"abstract":"Objectives: Endometriosis (EM) is a chronic gynecological condition characterized by the growth of endometrial-like tissue outside the uterus. Diagnosis has traditionally been challenging due to nonspecific symptoms and reliance on invasive procedures like laparoscopy. Recently, extracellular vesicles (EVs) have been implicated in EM pathogenesis, offering potential diagnostic and therapeutic applications. This study systematically reviews the role of EVs in EM.Materials and methods: A Preferred Reporting Items for Systematic Reviews and Meta-analyses -guided systematic review was conducted. On March 3, 2024, PubMed, Medline, and Scopus were searched using the keywords \"endometriosis\" and either \"extracellular vesicles,\" \"EV,\" or \"EVs,\" along with \"treatment,\" \"monitoring,\" or \"diagnosis.\" The review included English-language original papers published between 2019 and 2024 focusing on EVs in EM. Studies on animals and those lacking direct references to EM were excluded from the study.Results: A total of 12 studies, comprising 657 patients, met the inclusion criteria. The studies examined EV cargo for diagnostic and therapeutic applications, with MicroRNAs (miRNAs) being the most frequently analyzed component. Five studies discussed miRNAs as potential diagnostic markers. EVs were also studied for their role in EM pathogenesis, including cell communication, immunomodulation, and angiogenesis.Conclusion: EVs show promise as noninvasive biomarkers for early-stage EM detection and management. Their involvement in disease pathogenesis suggests potential therapeutic applications. Identifying specific exosomal markers related to EM remains an active area of research.","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"15 1","pages":"65-74"},"PeriodicalIF":1.7,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12965498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147379124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of Pregnancy Outcomes and Influencing Factors in Patients with Uterine Fibroids after High-intensity Focused Ultrasound Ablation. 子宫肌瘤高强度聚焦超声消融后妊娠结局及影响因素分析。

IF 1.7

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.4103/gmit.GMIT-D-24-00059

Diego Armando Burgos Briones, Rong Ma, Wen Zhou, Yu Xiong, Lian Zhang, Min Zou, Zhibiao Wang

{"title":"Analysis of Pregnancy Outcomes and Influencing Factors in Patients with Uterine Fibroids after High-intensity Focused Ultrasound Ablation.","authors":"Diego Armando Burgos Briones, Rong Ma, Wen Zhou, Yu Xiong, Lian Zhang, Min Zou, Zhibiao Wang","doi":"10.4103/gmit.GMIT-D-24-00059","DOIUrl":"10.4103/gmit.GMIT-D-24-00059","url":null,"abstract":"Objectives: The objective is to analyze factors influencing pregnancy outcomes in patients with uterine fibroids after high-intensity focused ultrasound (HIFU) treatment.Materials and methods: Patients with uterine fibroids who wished to have children underwent HIFU treatment at Chongqing Haifu Hospital from April 2011 to May 2024 were retrospectively reviewed. HIFU treatment results were evaluated using magnetic resonance imaging, and the postoperative pregnancy outcomes were evaluated.Results: 302 out of 748 (40.4%) patients became pregnant after HIFU, including 88.1% (273/310) in natural and 11.9% (37/310) in assisted reproduction. At the end of follow-up, 273 patients had 281 successful deliveries. No patient had a uterine rupture during pregnancy or delivery after HIFU. Patients with multiple fibroids had a lower probability of conception compared to those with a single fibroid (odds ratio [OR] >1, P < 0.05). A larger NPV ratio was associated with a higher likelihood of pregnancy (OR > 1, P < 0.05). Submucosal fibroids were an independent risk factor for pregnancy compared to subserosal fibroids (OR > 1, P < 0.05). In contrast, intramural or mixed-type fibroids were independent protective factors for pregnancy compared to submucosal fibroids (OR < 1, P < 0.05). A significant difference in NPV ratio and number of fibroids was also observed between patients in the delivery group and the miscarriage group (P < 0.05).Conclusion: HIFU treatment is safe and effective for patients with uterine fibroids who wish to have a child. Older age, multiple fibroids, submucosal fibroids, and low NPV have negative effects on pregnancy.","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"15 1","pages":"44-51"},"PeriodicalIF":1.7,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12965502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147379138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in Pelvic Organ Prolapse Management. 盆腔器官脱垂的治疗进展。

IF 1.7

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.4103/gmit.GMIT-D-25-00059

Chyi-Long Lee

引用次数: 0

A Comparison of the Postoperative Outcomes of Laparoscopic Sacrocolpopexy and Transvaginal Surgery Using ORIHIME^® Mesh with Wide Arms for Pelvic Organ Prolapse. 腹腔镜骶colpop固定术与经阴道手术采用ORIHIME®宽臂补片治疗盆腔器官脱垂的疗效比较

IF 1.7

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.4103/gmit.GMIT-D-24-00024

Kenji Kuroda, Koetsu Hamamoto, Kazuki Kawamura, Ayako Masunaga, Akio Horiguchi, Keiichi Ito

{"title":"A Comparison of the Postoperative Outcomes of Laparoscopic Sacrocolpopexy and Transvaginal Surgery Using ORIHIME® Mesh with Wide Arms for Pelvic Organ Prolapse.","authors":"Kenji Kuroda, Koetsu Hamamoto, Kazuki Kawamura, Ayako Masunaga, Akio Horiguchi, Keiichi Ito","doi":"10.4103/gmit.GMIT-D-24-00024","DOIUrl":"10.4103/gmit.GMIT-D-24-00024","url":null,"abstract":"Objectives: Both transvaginal mesh surgery with wide arms (TVMWA) and laparoscopic sacrocolpopexy (LSC) are effective surgical treatments for pelvic organ prolapse (POP) with reportedly low recurrence rates. In the present study, we compared the postoperative outcomes of TVMWA and LSC.Materials and methods: We retrospectively evaluated 142 patients with POP who underwent LSC or TVMWA at our hospital. We measured the changes in lower urinary tract symptoms before and after surgery using the International Prostate Symptom Score (IPSS) plus Quality of Life (QOL) score, Overactive Bladder Symptom Score (OABSS), International Consultation on Incontinence Questionnaire Short-Form (ICIQ-SF), postvoiding residual urine volume (PVR), and 60-min pad weight testing.Results: The median blood loss was much lower in the LSC group than in the TVMWA group. However, the median surgical duration was significantly longer in the LSC group than in the TVMWA group (both P < 0.0001). The PVR, IPSS plus QOL scores, OABSS, and ICIQ-SF scores all decreased significantly after surgery in both the groups. There were no significant changes between the pre- and postoperative 60-min pad weights in either group. There were no significant differences in the rate of stress urinary incontinence, mesh exposure, or prolapse recurrence after surgery between the two groups. ICIQ-SF scores were significantly more improved in the TVMWA group compared to the LSC group.Conclusion: We conclude that both TVMWA and LSC are effective surgical methods of ameliorating POP. However, considering the burden such as longer operative time on the patient treated with LSC, we recommend more frequent employment of TVMWA.","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"15 1","pages":"52-57"},"PeriodicalIF":1.7,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12965512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147379163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vitamin D Gene Polymorphisms in Polycystic Ovary Syndrome: Implications for Cardiovascular Risk. 多囊卵巢综合征的维生素D基因多态性：对心血管风险的影响

IF 1.7

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.4103/gmit.GMIT-D-25-00014

Anna Vittoria Mattioli

引用次数: 0

Bilateral Vulvar Ecchymosis after Laparoscopic Myomectomy. 腹腔镜子宫肌瘤切除术后双侧外阴瘀斑。

IF 1.7

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.4103/gmit.GMIT-D-25-00004

Liang-Ying Ke, Chang-Lin Yeh, Cheng-Yu Long

引用次数: 0

Points to Remember in Ovarian Eponyms Pearls: Dr. Fritz Malignant Brenner Tumor. 卵巢同名珍珠：弗里茨博士恶性布伦纳肿瘤。

IF 1.7

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.4103/gmit.GMIT-D-25-00042

Arvind Kumar, Ritu Thakur, Ravi Hari Phulware

引用次数: 0

Synergistic Efficacy and Safety Evaluation of Focused Ultrasound Ablation Surgery Combined with Thermal Balloon Endometrial Ablation in Treating Adenomyosis: A Prospective Controlled Study. 聚焦超声消融联合热球囊子宫内膜消融治疗子宫腺肌症的协同疗效及安全性评价：一项前瞻性对照研究。

IF 1.7

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.4103/gmit.GMIT-D-25-00096

Ren Yingqiang, Hu Zhonglian, Yin Li, Wang Jinwei, Li Yuan, Gao Jun, Chen Jinyun, Pu Yuanfang

{"title":"Synergistic Efficacy and Safety Evaluation of Focused Ultrasound Ablation Surgery Combined with Thermal Balloon Endometrial Ablation in Treating Adenomyosis: A Prospective Controlled Study.","authors":"Ren Yingqiang, Hu Zhonglian, Yin Li, Wang Jinwei, Li Yuan, Gao Jun, Chen Jinyun, Pu Yuanfang","doi":"10.4103/gmit.GMIT-D-25-00096","DOIUrl":"10.4103/gmit.GMIT-D-25-00096","url":null,"abstract":"Objectives: The objective of this study was to evaluate the synergistic efficacy and safety of focused ultrasound ablation therapy (FUAS) combined with thermal balloon endometrial ablation (TBEA) in treating adenomyosis.Materials and methods: A total of 103 patients diagnosed with adenomyosis admitted to Nanchuan District People's Hospital of Chongqing from July 2022 to December 2023 were randomized into two groups. The experimental group (n = 36) received FUAS combined with TBEA, whereas the control group (n = 67) underwent FUAS alone. All patients were followed up for 12 months. Clinical symptoms, serological markers, imaging parameters, and adverse events were compared between groups.Results: At 12 months posttreatment, both groups showed significant improvements in key outcomes. The experimental group exhibited superior outcomes in reducing pictorial blood loss assessment chart scores, improving health-related quality of life scores, lowering CA125 levels, and elevating hemoglobin levels compared to the control group (all P < 0.05). No significant differences in follicle-stimulating hormone (FSH) levels were observed between groups. No severe complications occurred.Conclusion: FUAS combined with TBEA effectively reduces uterine volume, alleviates dysmenorrhea, decreases menstrual flow, improves anemia, and preserves ovarian function (as evidenced by stable FSH levels) with minimal adverse effects. This combined therapy demonstrates enhanced efficacy and safety over monotherapy, providing a promising comprehensive treatment for adenomyosis.","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"15 1","pages":"58-64"},"PeriodicalIF":1.7,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12965499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147379130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0