{"title":"Exploring Intersections: Endometrial and Ovarian Cancer Investigations.","authors":"Chyi-Long Lee","doi":"10.4103/gmit.GMIT-D-25-00020","DOIUrl":"10.4103/gmit.GMIT-D-25-00020","url":null,"abstract":"","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"103-104"},"PeriodicalIF":1.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ruptured Ectopic Pregnancy Misdiagnosed with Ruptured Corpus Luteum: A Case Report and Literature Review.","authors":"Wing Yu Sharon Siu, Dah-Ching Ding","doi":"10.4103/gmit.GMIT-D-24-00006","DOIUrl":"10.4103/gmit.GMIT-D-24-00006","url":null,"abstract":"<p><p>Ectopic pregnancy can be mistakenly reported as a ruptured corpus luteum. A 22-year-old woman was initially misdiagnosed with a ruptured corpus luteum and treated with analgesics at a local clinic. Persistent symptoms led her to our hospital, where a pelvic ultrasound revealed a 5.2 cm ×4.8 cm hematoma. Despite the significant hematoma, her vital signs were stable. A urine pregnancy test was positive, β-hCG was 5553 mIU/mL, and hemoglobin (Hb) was 6.3 g/dL. After a blood transfusion, methotrexate (MTX) was administered, reducing β-hCG to 4428 mIU/mL by day 5. Four weeks later, β-hCG was 723.6 mIU/mL, and a second MTX dose was given. Three weeks later, β-hCG was 4.7 mIU/mL, and Hb was 12.4 g/dL. In conclusion, a \"wait-and-see\" approach with serial hCG testing and repeated ultrasounds is recommended in unclear cases.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"189-192"},"PeriodicalIF":1.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165678/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Safety and Efficacy of High-intensity Focused Ultrasound Ablation for Patients with Submucosal Fibroids without Fertility Needs: A Single-center Real-world Data Retrospective Study.","authors":"Xue Shao, Guohua Huang, Yanglu Liu, Hao Zhang, Shuang Luo, Rui Liu","doi":"10.4103/gmit.GMIT-D-24-00045","DOIUrl":"10.4103/gmit.GMIT-D-24-00045","url":null,"abstract":"<p><strong>Objectives: </strong>To analyze clinical outcomes and the factors that influence the therapeutic outcomes of high-intensity focused ultrasound (HIFU) ablation for different types of submucosal uterine fibroids.</p><p><strong>Materials and methods: </strong>A total of 626 patients without fertility requirements who underwent HIFU ablation for submucosal uterine fibroids at Suining Central Hospital from November 1, 2010, to December 31, 2023, were retrospectively reviewed. The safety and clinical efficacy of HIFU ablation therapy for submucosal uterine fibroids were evaluated.</p><p><strong>Results: </strong>The patients with submucosal uterine fibroids presented increased menstrual volume in 25.24% (158/626) of patients, prolonged menstrual period in 16.93% (106/626) of patients, lower abdominal pain in 5.59% (35/626) of patients, and anemia in 39.46% (247/626) of patients in this study. The average nonperfused volume ratio of type 0, type I, and type II submucosal uterine fibroids was 89.00%, 88.54%, and 85.33%, respectively. No severe adverse events occurred in any of the patients during or after HIFU treatment. Twenty-five patients received reintervention treatment (HIFU or surgical fibroid resection) in 6 months to 7.28 years after HIFU. A significant difference was observed in postoperative combined treatment between the reintervention and non-reintervention group (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>HIFU ablation for type 0, type I, and type II submucosal uterine fibroids is safe and effective. The combination management mode after HIFU could reduce the chance of reintervention treatment.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"137-144"},"PeriodicalIF":1.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ineffective Pelvic Magnetic Resonance Imaging for the Detection of a Levonorgestrel-releasing Intrauterine System Straying into the Abdominal Cavity.","authors":"Kensuke Ogino, Hiroe Ito, Koji Fujimori, Junko Nakagawa, Keiichi Isaka, Yasufumi Oishi","doi":"10.4103/gmit.GMIT-D-24-00009","DOIUrl":"10.4103/gmit.GMIT-D-24-00009","url":null,"abstract":"<p><p>The levonorgestrel intrauterine system (LNG-IUS) is used by patients for dysmenorrhea, but cases of uterine perforation have been observed. This patient underwent replacement 5 years after the initial LNG-IUS insertion, but persistent abdominal pain led to a visit to her previous gynecologist. Transvaginal ultrasonography and magnetic resonance imaging (MRI) at the time of the visit did not detect LNG-IUS. A subsequent computed tomography (CT) scan clearly showed the entire T-shape of the LNG-IUS on the sagittal plane and revealed the presence of the LNG-IUS in the abdominal cavity. Laparoscopic observation revealed that the adhesion of the LNG-IUS was mild, and it could be removed without damaging other organs. The patient was discharged without problems on the third postoperative day. LNG-IUS extraction via ultrasonography and MRI is considered challenging due to its material characteristics. We report a case of intrabdominal LNG-IUS migration where CT and X-ray proved useful in the localization of LNG-IUS.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"174-177"},"PeriodicalIF":1.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Restore the Continuity of Uterus-Cervix-Vagina for Cervical Restenosis after Cervicovaginal Reconstruction: A Case Report.","authors":"Xiaotong Liu, Xuyin Zhang, Keqin Hua","doi":"10.4103/gmit.gmit_63_24","DOIUrl":"10.4103/gmit.gmit_63_24","url":null,"abstract":"<p><p>Congenital cervical and vaginal atresia in the presence of a functioning endometrium is an extremely rare disease. Cervicovaginal reconstruction preserves fertility for these patients. We present the case of a 20-year-old patient who had cervicovaginal reconstruction 7 years ago due to congenital cervical and vaginal aplasia. However, with the cervical catheter falling off this year, this patient had severe dysmenorrhea and was diagnosed with cervical restenosis. Finally, this patient was successfully treated with laparoscopic cervical reconstruction. Restoring the continuity of uterus-cervix-vagina for cervical restenosis after cervicovaginal reconstruction is feasible. After cervicovaginal reconstruction, the placement time of the cervical catheter should be extended appropriately to avoid cervical restenosis.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"182-184"},"PeriodicalIF":1.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shinichi Togami, Nozomi Furuzono, Mika Mizuno, Hiroaki Kobayashi
{"title":"Comparative Analysis of Surgical Outcomes between the hinotori™ Surgical Robot System and da Vinci® Xi in Robot-assisted Sacrocolpopexy for Pelvic Organ Prolapse.","authors":"Shinichi Togami, Nozomi Furuzono, Mika Mizuno, Hiroaki Kobayashi","doi":"10.4103/gmit.GMIT-D-24-00018","DOIUrl":"10.4103/gmit.GMIT-D-24-00018","url":null,"abstract":"<p><strong>Objectives: </strong>Numerous studies have compared robotic sacrocolpopexy (RSC) and laparoscopic sacrocolpopexy; however, comparisons of RSC with the hinotori™ surgical robot system (SRS) are limited. This study aimed to compare surgical factors and outcomes of RSC using the hinotori™ SRS and da Vinci® Xi for pelvic organ prolapse.</p><p><strong>Materials and methods: </strong>A retrospective analysis was conducted on 80 patients who underwent RSC at Kagoshima University Hospital between January 2017 and June 2024. Patients were divided into two groups based on the robotic system used: hinotori™ SRS (<i>n</i> = 22) and da Vinci® Xi (<i>n</i> = 58). Surgical factors, including operative time, cockpit/console time, blood loss, length of hospital stay, and complications, were evaluated.</p><p><strong>Results: </strong>The median operative time and cockpit/console times for the hinotori™ SRS were 286 (range: 185-612) min and 250 (123-440) min, respectively, and those for the da Vinci® Xi were 221 (150-430) min and 194 (93-337) min, respectively; values for the hinotori™ SRS were significantly higher. No significant differences were found in blood loss, length of hospital stay, or complications between the two groups. The longer operative times for the hinotori™ SRS were likely due to the learning curve associated with fewer cases.</p><p><strong>Conclusion: </strong>Despite longer operative times, the hinotori™ SRS demonstrates surgical outcomes comparable to those of the da Vinci® Xi, indicating that RSC can be performed safely and effectively using the hinotori™ SRS. Future studies with larger sample sizes are needed to validate these findings.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"132-136"},"PeriodicalIF":1.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comprehensive Evaluation of Ovarian Growths in Young Women.","authors":"Mukta Agarwal, Smita Singh, Sudwita Sinha","doi":"10.4103/gmit.GMIT-D-24-00030","DOIUrl":"10.4103/gmit.GMIT-D-24-00030","url":null,"abstract":"<p><strong>Objectives: </strong>Adolescents represent a significant demographic in hospital outpatient visits, and it is important to give them special consideration and conduct a thorough examination for any adnexal pathology. The research aimed to study adnexal masses in adolescent females aged 10-19 years, including their clinical, biochemical, and radiological evaluations. The goal was to develop a treatment plan and analyze its relationship with histopathological findings.</p><p><strong>Materials and methods: </strong>The study was carried out at a single center and included 124 participants in a descriptive research design.</p><p><strong>Results: </strong>During the study, 6.2% of adolescents had adnexal masses, with abdominal discomfort being the most common symptom (66.12%). Ultrasound scans showed cystic, solid, or complex masses in 41.6%, 23.4%, and 35% of cases, respectively. In 53.4% of the patients, tumors exceeding 10 cm in size were identified, while 66.67% exhibited elevated levels of tumor markers. Surgical procedures were necessary for 48.5% of adolescents, with laparoscopic cystectomy being carried out in 48.34% and staging laparotomy in 46.66%.</p><p><strong>Conclusion: </strong>Small asymptomatic cysts need to be monitored, but larger complex or solid tumors must all be thoroughly examined to rule out malignancy. Early diagnosis and preservation of the ovary should be the aim of treatment. Although guidelines exist for the treatment of adnexal masses in adults, there is limited information available in the literature regarding adolescents. Therefore, it is crucial to establish an appropriate surgical plan that preserves fertility in this vulnerable age group.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"145-151"},"PeriodicalIF":1.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shinichi Togami, Nozomi Furuzono, Mika Mizuno, Hiroaki Kobayashi
{"title":"Comparison of Surgical and Oncological Outcomes between Laparoscopic and Open Surgeries in Patients with Stage IA1 Cervical Cancer.","authors":"Shinichi Togami, Nozomi Furuzono, Mika Mizuno, Hiroaki Kobayashi","doi":"10.4103/gmit.GMIT-D-24-00019","DOIUrl":"10.4103/gmit.GMIT-D-24-00019","url":null,"abstract":"<p><strong>Objectives: </strong>Laparoscopic surgery improves patient quality of life; however, its utility in stage IA1 cervical cancer remains debatable. This study aimed to compare the surgical and oncological outcomes of laparoscopic versus open surgery in patients with stage IA1 cervical cancer.</p><p><strong>Materials and methods: </strong>Thirty-four patients, including 20 who underwent laparoscopic surgery and 14 who underwent open surgery, were enrolled in this study. The surgical and oncological outcomes were compared between the laparoscopic and open surgery groups.</p><p><strong>Results: </strong>No statistically significant differences were observed between the laparoscopic and open surgery groups in terms of median age, body mass index, final pathological type, the presence of lymphovascular space invasion, and operation time. Patients who underwent laparoscopic surgery had significantly lower blood loss (38 vs. 170 mL, <i>P</i> < 0.001) and shorter postoperative hospital stay (5 vs. 7.5 days, <i>P</i> < 0.0001) than those who underwent open surgery. Oncological recurrence was observed in only one patient in the laparoscopic group (vaginal cuff). The 3-year recurrence-free survival rate was 94.7% and 100% for the laparoscopic and open surgery groups, respectively, with no statistically significant difference.</p><p><strong>Conclusion: </strong>Laparoscopic surgery resulted in reduced blood loss and shorter hospital stay, with oncological outcomes comparable to those of open surgery in patients with stage IA1 cervical cancer. These findings highlight the potential benefits of laparoscopic surgery in improving surgical outcomes for patients with stage IA1 cervical cancer.</p>","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"14 2","pages":"152-156"},"PeriodicalIF":1.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}