Gynecology and Minimally Invasive Therapy-GMIT最新文献_第2页

Insulin Resistance in Polycystic Ovary Syndrome: Mechanistic Insights and Therapeutic Perspectives Independent of Obesity. 多囊卵巢综合征的胰岛素抵抗：独立于肥胖的机制见解和治疗观点。

IF 2.1

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-07-17 eCollection Date: 2026-07-01 DOI: 10.4103/gmit.GMIT-D-25-00185

Bethal Abhinethri, Dhannya Nalini Harindranathan, Shilia Jacob Kurian

{"title":"Insulin Resistance in Polycystic Ovary Syndrome: Mechanistic Insights and Therapeutic Perspectives Independent of Obesity.","authors":"Bethal Abhinethri, Dhannya Nalini Harindranathan, Shilia Jacob Kurian","doi":"10.4103/gmit.GMIT-D-25-00185","DOIUrl":"10.4103/gmit.GMIT-D-25-00185","url":null,"abstract":"Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting women everywhere. PCOS without insulin resistance (IR) is much less severe than PCOS with IR, and the severity is less in the nonobese. Management and treatment of IR are imperative in PCOS management. As a major cause of female fertility issues, PCOS is yet to be fully understood. The symptoms of PCOS create a mental burden on the patient, which needs to be taken care of. Management of IR has significantly helped in reducing the symptoms of PCOS. Many studies have shown that there is no one solution to IR and PCOS. In this review, we examine the various pathophysiological processes, clinical impacts, and management of PCOS and IR. We also focus on how the combination of lifestyle changes, such as improving activity levels, consuming nutrient-rich whole foods, maintaining good mental health, quality sleep, pharmaceutical support and dietary supplements, is currently recognized as the management of IR and PCOS.","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"15 3","pages":"199-206"},"PeriodicalIF":2.1,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13427152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148654271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Success of Total Laparoscopic Hysterectomy with Variable-view Rigid Endoscopy for Large Polycystic Liver in a Patient with Autosomal Dominant Polycystic Kidney Disease. 可变视点刚性内窥镜下全腹腔镜子宫切除术治疗常染色体显性多囊肾病大多囊肝1例成功。

IF 2.1

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-07-17 eCollection Date: 2026-07-01 DOI: 10.4103/gmit.GMIT-D-25-00104

Yoichi Aoki, Yusuke Toyohara, Takato Goto, Hiroyuki Kanao

引用次数: 0

A Randomized Clinical Trial Comparing the Effect of Rectal Misoprostol with Intramyometrial Vasopressin on Blood Loss during Laparoscopic Myomectomy. 一项比较直肠米索前列醇与子宫内膜内加压素对腹腔镜子宫肌瘤切除术出血量影响的随机临床试验。

IF 2.1

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-07-17 eCollection Date: 2026-07-01 DOI: 10.4103/gmit.GMIT-D-25-00083

Sangam Jha, Vikas Chandra Jha, Sharda Jha

{"title":"A Randomized Clinical Trial Comparing the Effect of Rectal Misoprostol with Intramyometrial Vasopressin on Blood Loss during Laparoscopic Myomectomy.","authors":"Sangam Jha, Vikas Chandra Jha, Sharda Jha","doi":"10.4103/gmit.GMIT-D-25-00083","DOIUrl":"10.4103/gmit.GMIT-D-25-00083","url":null,"abstract":"Objectives: This study aimed to compare the efficacy of rectal misoprostol combined with intramyometrial normal saline versus intramyometrial vasopressin in reducing blood loss during laparoscopic myomectomy.Materials and methods: This was a randomized, double blind, controlled trial (CTRI/2023/05/053204). A total of 70 women scheduled for laparoscopic myomectomy were enrolled and equally randomized into two groups: Group I (received rectal misoprostol 400 µg 1 h before surgery) and Group II (received intramyometrial vasopressin 20 IU in 200 ml NS dilution). Final analysis was conducted on 64 patients due to missing data (4 in Group I and 2 in Group II). The primary outcome was intraoperative blood loss.Results: Baseline clinical characteristics were similar between the groups. Intraoperative blood loss was significantly higher in the misoprostol Group I compared to the vasopressin Group II (320.9 ± 131.9 mL vs. 246 ± 119.3 mL; P = 0.02). Similarly, the mean drop in hemoglobin was greater in Group I (2.38 ± 1 g/dL) than in Group II (1.5 ± 1.2 g/dL; P = 0.02). Although operative time was longer in Group I (median [95% confidence interval]: 120 [90-158.2] min vs. 96 [90-135.89] min), the difference was not statistically significant (P = 0.49). Blood transfusion was required in 4 patients in Group I and 1 patient in Group II. Intraoperative mean arterial pressure was significantly higher in Group II (110 ± 13.3 mmHg vs. 101 ± 13.7 mmHg; P = 0.02). Postoperative complications were comparable, with low rates of fever in both groups.Conclusion: Vasopressin was more effective than misoprostol in reducing intraoperative blood loss and postoperative hemoglobin drop during laparoscopic myomectomy.","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"15 3","pages":"254-260"},"PeriodicalIF":2.1,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13427204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148654268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vaginal Natural Orifice Transluminal Endoscopic Surgery Myomectomy for a Rare Variant of Leiomyoma. 阴道自然口腔内窥镜手术切除一例罕见型平滑肌瘤。

IF 2.1

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-07-17 eCollection Date: 2026-07-01 DOI: 10.4103/gmit.GMIT-D-25-00114

Cihan Comba, Ulya Uskent, Ali Aslan Demir, Sakir Volkan Erdogan, Omer Demir, Huseyin Cengiz

引用次数: 0

Reimagining Surgical Boundaries: Advances in Minimally Invasive Surgery for Transplant. 重塑手术界限：移植微创手术的进展。

IF 2.1

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-07-17 eCollection Date: 2026-07-01 DOI: 10.4103/gmit.GMIT-D-26-00055

Chyi-Long Lee

引用次数: 0

Novel Intraoperative Transvaginal Ultrasonographic Needle Guidance in Laparoscopic Excision of Elusive Intramural Myomas: Enhancing Precision, Minimizing Hemorrhage, and Optimizing Surgical Outcomes. 新型术中经阴道超声针引导在腹腔镜下切除难以捉摸的子宫肌瘤：提高精度，减少出血，优化手术效果。

IF 2.1

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-07-17 eCollection Date: 2026-07-01 DOI: 10.4103/gmit.GMIT-D-25-00062

Binarwan Halim, Melissa Edelweishia, Edward Muljadi

{"title":"Novel Intraoperative Transvaginal Ultrasonographic Needle Guidance in Laparoscopic Excision of Elusive Intramural Myomas: Enhancing Precision, Minimizing Hemorrhage, and Optimizing Surgical Outcomes.","authors":"Binarwan Halim, Melissa Edelweishia, Edward Muljadi","doi":"10.4103/gmit.GMIT-D-25-00062","DOIUrl":"10.4103/gmit.GMIT-D-25-00062","url":null,"abstract":"Laparoscopy for intramural uterine myomas lacking serosal protrusion or hysteroscopic accessibility remains surgically challenging due to limited visualization and precise localization. This prospective case series evaluated the efficacy of intraoperative transvaginal ultrasonographic guidance in augmenting laparoscopic excision of occult intramural fibroids. Fifteen patients underwent laparoscopy with concurrent transvaginal ultrasound-guided needle localization, utilizing a 17- or 18-gauge single-lumen needle affixed to a transvaginal probe. The needle, introduced via the vaginal fornix, facilitated real-time intrauterine mapping to pinpoint myoma boundaries and optimize serosal incision placement. Complete enucleation was achieved in all cases. This technique enhanced intraoperative precision by integrating dynamic imaging to overcome visual constraints inherent in conventional laparoscopy, minimizing collateral tissue disruption and hemorrhage through targeted incision planning. The findings underscore the adjunctive role of transvaginal ultrasonography in optimizing minimally invasive myomectomy for complex intramural fibroids, offering a reproducible strategy to improve surgical accuracy, completeness of resection, and hemostatic control.","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"15 3","pages":"274-279"},"PeriodicalIF":2.1,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13427160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148654696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laparoscopic Assessment of the Ovaries after Resolving the Endometriomas with Ultrasound-guided Transvaginal Ethanol Sclerotherapy. 超声引导下经阴道乙醇硬化治疗子宫内膜异位瘤后卵巢的腹腔镜评估。

IF 2.1

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-07-17 eCollection Date: 2026-07-01 DOI: 10.4103/gmit.GMIT-D-25-00055

Izabela Dymanowska, Karolina Frankowska, Sara Moqbil, Monika Abramiuk, Piotr Stachurski, Elżbieta Witt, Grzegorz Polak

{"title":"Laparoscopic Assessment of the Ovaries after Resolving the Endometriomas with Ultrasound-guided Transvaginal Ethanol Sclerotherapy.","authors":"Izabela Dymanowska, Karolina Frankowska, Sara Moqbil, Monika Abramiuk, Piotr Stachurski, Elżbieta Witt, Grzegorz Polak","doi":"10.4103/gmit.GMIT-D-25-00055","DOIUrl":"10.4103/gmit.GMIT-D-25-00055","url":null,"abstract":"Ultrasound-guided transvaginal ethanol sclerotherapy belongs to one of the minimally invasive methods for endometrioma management. Nevertheless, some reports suggested a possible link between the method and the presence of pelvic adhesions. Therefore, our study aimed to describe ultrasound-guided transvaginal sclerotherapy with high-percentage ethanol, which resulted in the preservation of normal anatomy of the minor pelvis and the normal appearance of affected ovaries in the laparoscopic images obtained during postsclerotherapy surgeries. We present four cases of patients who underwent laparoscopic surgeries several months after ethanol sclerotherapies for ovarian endometriomas. During sclerotherapies, cyst fluid was aspirated under ultrasound guidance, cyst cavities were flushed with saline, and then filled with 96% ethanol to 60% of their initial volume for 10 min. The reported cases demonstrate that ultrasound-guided transvaginal ethanol sclerotherapy did not cause excessive adhesion formation or affect ovarian morphology. Therefore, it seems that this treatment method does not adversely affect fertility.","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"15 3","pages":"269-273"},"PeriodicalIF":2.1,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13427159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148654576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Minimally Invasive Innovation in Endometriosis and Adenomyosis: Toward Fertility Preservation and Symptom Relief. 子宫内膜异位症和子宫腺肌症的微创创新：对生育能力的保留和症状的缓解。

IF 2.1

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-05-19 eCollection Date: 2026-04-01 DOI: 10.4103/gmit.GMIT-D-25-00191

Kuo-Chung Lan

引用次数: 0

Treatment Options for Uterine Fibroids Using Microwave and Radiofrequency. 使用微波和射频治疗子宫肌瘤的选择。

IF 2.1

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-05-19 eCollection Date: 2026-04-01 DOI: 10.4103/gmit.gmit_82_24

Zhihui Sun, Shang-Min Liu, Chyi-Long Lee, Xiaoming Gong

{"title":"Treatment Options for Uterine Fibroids Using Microwave and Radiofrequency.","authors":"Zhihui Sun, Shang-Min Liu, Chyi-Long Lee, Xiaoming Gong","doi":"10.4103/gmit.gmit_82_24","DOIUrl":"10.4103/gmit.gmit_82_24","url":null,"abstract":"Minimally invasive thermal ablation therapies, including microwave ablation (MWA) and radiofrequency ablation (RFA), have emerged as effective alternatives to traditional surgical approaches for the management of symptomatic uterine fibroids. These techniques offer advantages such as reduced pain, minimal blood loss, and quicker recovery times. This mini-review integrates current evidence with clinical experience to evaluate the efficacy, safety, procedural characteristics, and cost-effectiveness of MWA and RFA, with additional comparisons to high-intensity focused ultrasound (HIFU) and magnetic resonance imaging-guided focused ultrasound surgery. Two clinical cases are presented to illustrate the application and outcomes of combining MWA or RFA with hysteroscopic resection. Available data suggest that MWA provides the shortest treatment duration and broad applicability, while RFA offers high ablation rates, especially for large or hypervascular fibroids. In contrast, HIFU is noninvasive and better tolerated but requires longer procedural time and has more stringent patient selection criteria. Treatment decisions should be individualized based on fibroid characteristics, patient preferences, and available resources. With appropriate patient selection and procedural expertise, these minimally invasive methods can significantly improve symptom control and quality of life.","PeriodicalId":45272,"journal":{"name":"Gynecology and Minimally Invasive Therapy-GMIT","volume":"15 2","pages":"114-120"},"PeriodicalIF":2.1,"publicationDate":"2026-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13299028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148346759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How to Promote Medical Safety on Minimally Invasive Gynecology Surgery - Japan Experience. 如何促进微创妇科手术的医疗安全-日本的经验。

IF 2.1

Gynecology and Minimally Invasive Therapy-GMIT Pub Date : 2026-05-19 eCollection Date: 2026-04-01 DOI: 10.4103/gmit.GMIT-D-25-00085

Osamu Wada-Hiraike

引用次数: 0