{"title":"Serum Chemerin Levels Correlate With Determinants of Metabolic Syndrome in Obese Children and Adolescents.","authors":"Hong-Jun Ba, Ling-Ling Xu, You-Zhen Qin, Hong-Shan Chen","doi":"10.1177/1179556519853780","DOIUrl":"https://doi.org/10.1177/1179556519853780","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate serum chemerin concentrations in obese children and adolescents and to investigate the associations of chemerin with body mass index (BMI), lipid levels, and insulin sensitivity.</p><p><strong>Methods: </strong>Forty-eight obese and 40 nonobese Chinese children and adolescents were included in the study. BMI and levels of chemerin, lipids, glucose, and insulin were measured following an overnight fast. The Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) and BMI standard deviation score (BMI-SDS) were determined for all participants.</p><p><strong>Results: </strong>Serum chemerin levels were found to be significantly higher in obese children and adolescents than in control group members (94.83 ± 5.99 ng/mL vs 56.43 ± 4.16 ng/mL, <i>P</i> < .001). There were significant correlations between chemerin and age, BMI, BMI-SDS, total triglyceride (TG) levels, insulin levels, and HOMA-IR. After controlling for age, we found that chemerin levels were also significantly correlated with BMI-SDS (r =+ 0.284, <i>P</i> = .008) and HOMA-IR (r =+ 0.241, <i>P</i> = .034). In a stepwise multiple regression analysis, we observed only BMI-SDS to be an important determinant of chemerin level.</p><p><strong>Conclusions: </strong>In our sample of Chinese children and adolescents, chemerin levels were significantly higher in the obese group than in the control group. Chemerin levels were positively correlated with BMI-SDS and HOMA-IR and negatively correlated with age. We thus believe that further study is necessary to investigate the risk of metabolic abnormalities in young obese children and adolescents.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"13 ","pages":"1179556519853780"},"PeriodicalIF":1.5,"publicationDate":"2019-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556519853780","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37344629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hanne Alves Bakke, Wiviane Abreu Cavalcante, Ilana Santos de Oliveira, Silvia Wanick Sarinho, Maria Teresa Cattuzzo
{"title":"Assessment of Motor Skills in Children With Visual Impairment: A Systematic and Integrative Review.","authors":"Hanne Alves Bakke, Wiviane Abreu Cavalcante, Ilana Santos de Oliveira, Silvia Wanick Sarinho, Maria Teresa Cattuzzo","doi":"10.1177/1179556519838287","DOIUrl":"https://doi.org/10.1177/1179556519838287","url":null,"abstract":"<p><p>This study aimed to review and examine the tools used to assess psychomotor performance of children with visual impairment. Databases, such as SCOPUS, MEDLINE/PubMed, Medline/EBSCO, Web of Science, LILACS, CINAHL, and ScienceDirect, were searched using Mesh terms. Data from manuscripts fully available in these databases between 1994 and 2017 (except CINAHL-2014) concerning the evaluation, tool development, or intervention for the improvement of motor skills in children (age, 7-10 years) with visual impairment were collected. The Critical Review Form-Quantitative Studies was used to evaluate the quality of the articles. As a result, 1113 articles were found, but only 24 met the inclusion criteria; 66.7% of the articles had moderate quality, with unsatisfactory results regarding the validity and reliability of the tools used to assess these children, as well as the absence of clinical importance and practical application in such studies. Only the Test of Gross Motor Development-2 and Movement Assessment Battery for Children-2 described data on the validation and reliability in visually impaired children. To minimize systematic errors and improve the quality of the investigations, increasing the number of studies regarding the tools, functionality of their activities, and testing the adaptions is necessary.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"13 ","pages":"1179556519838287"},"PeriodicalIF":1.5,"publicationDate":"2019-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556519838287","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37255452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Calixte Ida Penda, Francis A Ndongo, Anne-Cécile Z-K Bissek, Mathurin C Téjiokem, Casimir Sofeu, Else C Moukoko Eboumbou, Sandrine Mindjouli, Sophie Desmonde, Louis R Njock
{"title":"Practices of Care to HIV-Infected Children: Current Situation in Cameroon.","authors":"Calixte Ida Penda, Francis A Ndongo, Anne-Cécile Z-K Bissek, Mathurin C Téjiokem, Casimir Sofeu, Else C Moukoko Eboumbou, Sandrine Mindjouli, Sophie Desmonde, Louis R Njock","doi":"10.1177/1179556519846110","DOIUrl":"https://doi.org/10.1177/1179556519846110","url":null,"abstract":"<p><strong>Background: </strong>To accelerate access to pediatric HIV care in Cameroon, operational challenges in implementing HIV pediatric care need to be identified. The aim of this study was to assess the knowledge, attitudes, and practices of health care workers regarding pediatric HIV infection in Cameroon.</p><p><strong>Methods: </strong>A descriptive cross-sectional study was conducted over a 4-month period (April to August 2014) in 12 health facilities in 7 regions of Cameroon selected using systematic random sampling. Data were collected from interviews with health care providers and managers using standardized self-administered questionnaires and stored in the ACCESS software.</p><p><strong>Results: </strong>In total, 103 health care providers were included in this study, of which 59 (57.3%) were health workers and 44 (42.7%) community agents. Most of the health workers in charge of HIV pediatric care were nurses, requiring effective medical task shifting that was institutionalized in Cameroon. The knowledge of health care providers in relation to pediatric HIV care was acceptable. Indications for prescription of test for early infant diagnosis were known (96.1%), but their attitudes and practices regarding initiating antiretroviral therapy (ART) in infants less than 2 years (5.2%) and first-line ART protocols (25.4%) were insufficient, due to little information about standard procedures.</p><p><strong>Conclusion: </strong>Capacity building of health care providers and large-scale dissemination of normative national documents are imperative to improve HIV pediatric care in the health care facilities.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"13 ","pages":"1179556519846110"},"PeriodicalIF":1.5,"publicationDate":"2019-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556519846110","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37255454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jolie Straus, Sarah Coburn, Stephanie Maskell, Jessica Pappagianopoulos, Kathryn Cantrell
{"title":"Medical Encounters for Youth With Autism Spectrum Disorder: A Comprehensive Review of Environmental Considerations and Interventions.","authors":"Jolie Straus, Sarah Coburn, Stephanie Maskell, Jessica Pappagianopoulos, Kathryn Cantrell","doi":"10.1177/1179556519842816","DOIUrl":"https://doi.org/10.1177/1179556519842816","url":null,"abstract":"<p><p>Approximately 1 in 59 youth are currently diagnosed with autism spectrum disorder (ASD), a neurodevelopmental disorder. In comparison to typically developing peers, youth with ASD encounter hospitalization at higher rates due to their heightened health care needs. While visiting the hospital is a stressor for youth with neurotypical needs, the experience contains unique challenges for those with ASD. This systematic literature review highlights research that considers the psychosocial impact of the hospital environment on the coping and adjustment of youth with ASD. Specifically, the review focuses on recommendations and interventions that may be used by health care professionals while supporting this population as they encounter the health care system. Ninety-six articles were identified as meeting inclusion and exclusion criteria. The findings suggest that practicing clinicians should implement a wide variety of interventions for youth with ASD including diversion techniques, comfort positions, and picture schedules. Although there are published evidence-based interventions for supporting youth with ASD in the hospital, most clinicians lack ASD-specific training. This article concludes with recommendations for future research.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"13 ","pages":"1179556519842816"},"PeriodicalIF":1.5,"publicationDate":"2019-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556519842816","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37383717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pan-Cytokeratin Positive Fibroblastic Osteosarcoma of Jaw: An Extremely Rare Entity in a Pediatric Patient.","authors":"Aadithya B Urs, Priya Kumar, Jeyaseelan Augustine, Pankaj Sharma, Bhaskar Narayan","doi":"10.1177/1179556519842827","DOIUrl":"https://doi.org/10.1177/1179556519842827","url":null,"abstract":"<p><p>Osteosarcoma (OS) of jaws is a rare entity characterized by malignant osteoid formation and is most commonly seen in third to fourth decade of life. Here, we present a rare and intriguing case of a 14-year-old pediatric patient, who reported with a chief complaint of swelling in the left maxilla, which was rapidly increasing in size. Both cytokeratin AE1/3 and vimentin-positive spindled cells were seen arranged in storiform pattern with minimal areas of osteoid formation on histopathologic examination. The diagnosis of fibroblastic OS was confirmed by fluorescent in situ hybridization after excluding monomorphic synovial sarcoma. The patient underwent segmental resection of left maxilla and is on close follow-up. A PubMed search revealed that only 5 pediatric cases of fibroblastic OS have been published since 1991. Here, we highlight the diagnostic challenges encountered in reaching the histopathologic diagnosis.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"13 ","pages":"1179556519842827"},"PeriodicalIF":1.5,"publicationDate":"2019-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556519842827","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37180428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ioannis M Stavrakakis, Ioannis I Daskalakis, George E Magarakis, Zacharias Christoforakis, Maria S Katsafarou
{"title":"Ulnar Nerve Injuries Post Closed Forearm Fractures in Paediatric Population: A Review of the Literature.","authors":"Ioannis M Stavrakakis, Ioannis I Daskalakis, George E Magarakis, Zacharias Christoforakis, Maria S Katsafarou","doi":"10.1177/1179556519841876","DOIUrl":"https://doi.org/10.1177/1179556519841876","url":null,"abstract":"<p><p>Ulnar nerve injury as a result of closed forearm fractures in children is a rare but disastrous complication, affecting significantly the function of the upper extremity. The management of these injuries is still controversial in the literature. This is a review of small case series and case reports, in which an algorithm of treatment is proposed. A brief description of a relative case, which was treated successfully in our department, is presented as well. This case motivated the authors to perform this study.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"13 ","pages":"1179556519841876"},"PeriodicalIF":1.5,"publicationDate":"2019-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556519841876","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37166239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association Between Maternal Feeding Practices and Symptoms of Anxiety and Depression Among 6-Year-Old Children.","authors":"Shannon Flahive, Bhakti Chavan, Zelalem T Haile","doi":"10.1177/1179556519839334","DOIUrl":"https://doi.org/10.1177/1179556519839334","url":null,"abstract":"<p><strong>Background: </strong>Maternal feeding practices (MFPs) have been linked to childhood obesity and other eating disorders. However, population-based research examining the association between MFPs and children's emotional well-being is currently lacking.</p><p><strong>Methods: </strong>We examined 1241 participants from Year 6 Follow-Up of the Infant Feeding Practices Study II, conducted from March to June 2012 in the United States.</p><p><strong>Results: </strong>Approximately 57.5% and 47.8% of participants reported at least one symptom of childhood anxiety and depression, respectively. After adjusting for potential confounders, mothers who responded \"yes\" to \"If I did not guide or regulate my child's eating, he or she would eat too much of his or her favorite food\" had higher odds of having a child who has symptoms of depression and anxiety compared with mothers who responded \"no\" (odds ratio [OR], 95% confidence interval [CI]) (2.02; 1.47-2.78, <i>P</i> < .001) and (1.41, 1.05-1.91, <i>P</i> = .024), respectively. The odds of having a child who has symptoms of depression were lower among mothers who responded \"yes\" to \"I make sure that my child does not eat too many sweets or junk foods\" compared with mothers who responded \"no\" (0.49; 0.26-0.91, <i>P</i> = .020). Mothers who responded \"yes\" to \"I encourage my 6 year-old to eat all of the food on his or her plate\" had higher odds of having a child who has symptoms of anxiety compared with mothers who responded \"no\" (1.43; 1.01-2.05, <i>P</i> = .049).</p><p><strong>Conclusions: </strong>Controlling MFPs may influence a child's emotional well-being. Further research is needed to address the complex relationships between MFPs and psychosocial well-being in children.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"13 ","pages":"1179556519839334"},"PeriodicalIF":1.5,"publicationDate":"2019-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556519839334","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37291240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors Associated With High Blood Lead Levels in a Sample of 100 Children in Tehran.","authors":"Nasim Zamani, Narges Gholami, Hossein Hassanian-Moghaddam, Fariba Farnaghi, Latif Gachkar","doi":"10.1177/1179556518825451","DOIUrl":"https://doi.org/10.1177/1179556518825451","url":null,"abstract":"<p><strong>Background: </strong>Lead is considered a neurotoxic agent. We aimed to evaluate the blood lead level (BLL) in young population and determine probable risk factors of lead exposure in Iran.</p><p><strong>Methods: </strong>In a cross-sectional study, a total of 100 children were entered and their BLLs were checked.</p><p><strong>Results: </strong>In all, 25 and 8 patients had BLLs above 5 and 10 µg/dL, respectively. There was a significant univariate correlation between BLL and place of living, water pipe type, using dairy products, and stature in both cut-offs of 5 and 10 µg/dL. Binary regression analysis showed that pipe type was associated with high BLLs at cut-offs of 5 and 10 µg/dL, respectively. Also, there was an association between 50th percentile of stature for age and cut-off of 5 µg/dL.</p><p><strong>Conclusions: </strong>Higher BLLs may be seen in short stature pediatric population. Polyvinyl chloride (PVC) and polypropylene water pipes may even cause more release of lead and result in higher absorption of this metal in the pediatric population.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"13 ","pages":"1179556518825451"},"PeriodicalIF":1.5,"publicationDate":"2019-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556518825451","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37110663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tsunenori Isa, Ryuichi Sawa, Kohtaroh Torizawa, Shunsuke Murata, Takashi Saito, Aoi Ebina, Yuki Kondo, Yamato Tsuboi, Akimasa Fukuta, Shogo Misu, Rei Ono
{"title":"Reliability and Validity of the Japanese Version of the Physical Activity Questionnaire for Older Children.","authors":"Tsunenori Isa, Ryuichi Sawa, Kohtaroh Torizawa, Shunsuke Murata, Takashi Saito, Aoi Ebina, Yuki Kondo, Yamato Tsuboi, Akimasa Fukuta, Shogo Misu, Rei Ono","doi":"10.1177/1179556519835833","DOIUrl":"https://doi.org/10.1177/1179556519835833","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to examine the reliability and validity of the Japanese version of the Physical Activity Questionnaire for Older Children (PAQ-C) in Japanese children aged 9 to 12 years.</p><p><strong>Methods: </strong>A total of 210 children aged between 9 and 12 years participated. Internal consistency and test-retest reliability were evaluated using Cronbach alpha coefficient and intraclass correlation coefficient (ICC), respectively. Validity was evaluated using athletic competence (AC), self-efficacy (SE), body mass index (BMI), body fat percentage (%BF), cardiovascular fitness (CVF), and World Health Organization Health Behavior in School-aged Children (WHO HBSC) physical activity questionnaire.</p><p><strong>Results: </strong>Internal consistency was acceptable (alpha = 0.80) and test-retest reliability showed excellent agreement (ICC = 0.83). The PAQ-C score was significantly correlated with AC (<i>r</i> = 0.41), SE (<i>r</i> = 0.65), %BF (<i>r</i> = 0.19), and CVF (<i>r</i> = -0.32). The PAQ-C score of the active group classified by the WHO HBSC physical activity questionnaire (mean score ± standard deviation [SD] = 3.03 ± 0.57) was significantly higher than that of the inactive group (mean score ± SD = 2.27 ± 0.63, <i>P</i> < .01).</p><p><strong>Conclusions: </strong>The PAQ-C had acceptable reliability and validity. The PAQ-C is a useful instrument to evaluate physical activity for Japanese children aged 9 to 12 years.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"13 ","pages":"1179556519835833"},"PeriodicalIF":1.5,"publicationDate":"2019-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556519835833","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37265792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emergence of OXA-48 Carbapenemase Producing <i>Klebsiella pneumoniae</i> in a Neonatal Intensive Care Unit in Marrakech, Morocco.","authors":"Lahoucine Taoufik, Asma Amrani Hanchi, Bennaoui Fatiha, Slitine Nissrine, Maouainine Fadl Mrabih Rabou, Soraa Nabila","doi":"10.1177/1179556519834524","DOIUrl":"https://doi.org/10.1177/1179556519834524","url":null,"abstract":"<p><strong>Goal: </strong>This work aims to describe and explore the circumstances of appearance of <i>Klebsiella pneumoniae</i> producing OXA-48 carbapenemase, which has occurred in a neonatal intensive care service at the Mohammed VI University Hospital of Marrakech.</p><p><strong>Results: </strong>During February 2015, the alert was triggered by the isolation of 6 isolates of <i>K pneumoniae</i> with the same antibiotic susceptibility profile in the neonatal intensive care service, suggesting a possible outbreak. Blood cultures represented the main site of isolation of these isolates. The phenotypic study of the isolates made it possible to identify a strain of <i>K pneumoniae</i> susceptible to third-generation cephalosporins, ciprofloxacin, and aminoglycosides, and resistant to ertapenem, β-lactamases inhibitors (ticarcillin-clavulanate, piperacillin-tazobactam; amoxicillin-clavulanic acid), and cotrimoxazole. The genotypic study of the epidemic isolate revealed the presence of the <i>bla<sub>OXA-48</sub></i> gene. The action to be taken was the establishment of corrective measures to stop this epidemic to a multi-resistant germ transmitted by hand transmission. The reinforcement of hygiene measures and the awareness of the staff made it possible to put an end to the epidemic at March 30, 2015, without closing the service. The outcome of 6 infected newborns was fatal due to the fragile terrain and the inappropriate probabilistic antibiotic therapy.</p><p><strong>Conclusion: </strong>The production of carbapenemase in <i>K pneumoniae</i> is an emerging resistance mechanism that must be suspected and identified to offer targeted therapy and to limit its spread. The implementation of a local policy to control multidrug-resistant germs is essential to limit their dissemination in hospitals.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"13 ","pages":"1179556519834524"},"PeriodicalIF":1.5,"publicationDate":"2019-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556519834524","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37241657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}