Egyptian Heart Journal最新文献_第10页

Obesity paradox in heart failure patients – Female gender characteristics-KAMC-single center experience 心力衰竭患者的肥胖悖论-女性性别特征- kamc -单中心经验

IF 1.1

Egyptian Heart Journal Pub Date : 2017-09-01 DOI: 10.1016/j.ehj.2017.06.002

Sheeren Khaled , Rajaa Matahen

{"title":"Obesity paradox in heart failure patients – Female gender characteristics-KAMC-single center experience","authors":"Sheeren Khaled , Rajaa Matahen","doi":"10.1016/j.ehj.2017.06.002","DOIUrl":"10.1016/j.ehj.2017.06.002","url":null,"abstract":"<div><h3>Background/Introduction</h3><p>The correlation between low body mass index (BMI) and congestive heart failure (obesity paradox) has been described in the literature; However, the association between BMI and clinical outcome measures is not well characterized. Little is known about CHF in the Middle Eastern female population; most of the gender-specific information on heart failure comes from higher income “Western” countries.</p></div><div><h3>Objectives</h3><p>We aimed to identify the correlation between heart failure patients especially those with low BMI and clinical/safety outcome measures with focusing on female patients subgroup characteristics.</p></div><div><h3>Methods</h3><p>We performed group comparisons of statistically relevant variables using prospectively collected data of HFrEF patients hospitalized over a 12month period.</p></div><div><h3>Results</h3><p>The 167 patients (Group I) enrolled by this study with mean age of 59.64±12.9years, an EF score of 23.96±10.14, 62.9% had ischemic etiology, 12.5% were smoker, 18% had AF, 31.1% had received ICD/CRT-D and an estimated 8.85±9.5days length of stay (LOS). The low BMI group of patients (Group II) had means age of 58.7±14.5years, a significant lower EF score of 20.32±8.58, significantly higher 30, 90days readmission rates and in-house mortality (22%, 36.6% and 17.1% vs 10.2%, 20.4% and 6.6% respectively) and higher rates of CVA, TIA and unexplained syncope (19.5% vs 7.2%). Similarly, female patients with low BMI (Group IV) had lower EF score of 22.0±53, higher 30,90days readmission rates and in-house mortality (34.4%,43.8% and 25% vs 13.5%,21.6% and 5.4% respectively) and higher rates of CVA, TIA and unexplained syncope(10% vs 0%).</p></div><div><h3>Conclusion</h3><p>Our findings showed that heart failure patients with low BMI had poor adverse clinical outcome measures (poor EF, recurrent readmission, mortality and composite rates of CVA, TIA and unexplained syncope) which reflect the effect of obesity paradox in those patients with HFrEF. Female patient subgroup showed similar characteristic findings which also might reflect the value of gender-specific BMI related clinical outcomes.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"69 3","pages":"Pages 209-213"},"PeriodicalIF":1.1,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2017.06.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35980925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Pre-hospital and hospital delay in patients with non-ST elevation acute coronary syndromes in tertiary care 三级护理中非st段抬高急性冠状动脉综合征患者的院前和住院延误

IF 1.1

Egyptian Heart Journal Pub Date : 2017-09-01 DOI: 10.1016/j.ehj.2017.01.002

G.S. Youssef , H.H. Kassem , O.A. Ameen , H.S. Al Taaban , H.H. Rizk

{"title":"Pre-hospital and hospital delay in patients with non-ST elevation acute coronary syndromes in tertiary care","authors":"G.S. Youssef , H.H. Kassem , O.A. Ameen , H.S. Al Taaban , H.H. Rizk","doi":"10.1016/j.ehj.2017.01.002","DOIUrl":"10.1016/j.ehj.2017.01.002","url":null,"abstract":"<div><h3>Background</h3><p>Early presentation is desirable in all cases of acute prolonged chest pain. Causes of delayed presentation vary widely across geographic regions because of different patients' profile and different healthcare capabilities.</p></div><div><h3>Objectives</h3><p>To detect causes of delay of Non-ST elevation acute coronary syndrome (NSTE-ACS) patients in our country.</p></div><div><h3>Methods</h3><p>Patients admitted with NSTE-ACS were included. We recorded the time delay between the onsets of acute severe symptoms till their arrival to the hospital (Pre-hospital delay). We also recorded the time delay between the arrival to hospital and the institution of definitive therapy (hospital delay). Causes of pre-hospital delay are either patient- or transportation-related, while hospital delay causes are either staff- or system-related.</p></div><div><h3>Results</h3><p>We recruited 315 patients, 200 (63.5%) were males, 194 (61.6%) hypertensives, 180 (57.1%) diabetics, 106 (33.7%) current smokers and 196 (62.2%) patients had prior history of cardiac diseases. The mean pre-hospital delay time was 8.7±9.7h. Sixty-six percent of this time was due to patient-related causes and 34% of pre-hospital delay time was spent in transportation. The mean hospital delay time was 2.3±0.95h. In 89.8% of cases, the hospital delay was system-related while in 10.2% the reason was staff-related. The mean total delay time to definitive therapy was 11.0±9.8h.</p></div><div><h3>Conclusion</h3><p>Pre-hospital delay was mainly patient-related. Hospital delay was mainly related to healthcare resources. Governmental measures to promote ambulance emergency services may reduce the pre-hospital delay, while improving the utilization of healthcare resources may reduce hospital delay.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"69 3","pages":"Pages 177-181"},"PeriodicalIF":1.1,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2017.01.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35980921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Elevated troponin in patients with acute stroke – Is it a true heart attack? 急性中风患者肌钙蛋白升高——这是真正的心脏病发作吗?

IF 1.1

Egyptian Heart Journal Pub Date : 2017-09-01 DOI: 10.1016/j.ehj.2017.01.005

George V. Dous , Angela C. Grigos , Richard Grodman

引用次数: 9

Anomalous origin of left main coronary artery from the right sinus of Valsalva presenting as non ST elevation acute coronary syndrome: A case report 左冠状动脉主动脉异常起源于右Valsalva窦，表现为非ST段抬高急性冠脉综合征1例

IF 1.1

Egyptian Heart Journal Pub Date : 2017-09-01 DOI: 10.1016/j.ehj.2017.02.002

Anish Hirachan , Arun Maskey , Gopi Prasad Hirachan , Madhu Roka

{"title":"Anomalous origin of left main coronary artery from the right sinus of Valsalva presenting as non ST elevation acute coronary syndrome: A case report","authors":"Anish Hirachan , Arun Maskey , Gopi Prasad Hirachan , Madhu Roka","doi":"10.1016/j.ehj.2017.02.002","DOIUrl":"10.1016/j.ehj.2017.02.002","url":null,"abstract":"<div><p>Congenital anomalies of the coronary arteries are a cause of sudden cardiac death. Of the known anatomic variants, anomalous origination of a coronary artery from an opposite sinus of Valsalva (ACAOS) remains a major clinical issue and a challenging condition to treat. Congenital coronary anomalies are likely to be under-recognized, as completing an anatomic assessment in a very large portion of the population would seem unfeasible. However, we present a case report with image of a 49year old male presented with acute non-ST elevation ACS for which he underwent diagnostic angiography of the coronary system which revealed a common origin of both right and left main coronary artery from right sinus of Valsalva with significant obstructive lesion in the mid segment of right coronary artery. However, due to financial constraints CT angiography could not be done in this patient to identify the detail anatomy and the course of the anomalous left coronary artery origin (L-ACAOS). He was managed medically with dual antiplatelets, beta blockers, nitrates and ACE inhibitors.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"69 3","pages":"Pages 215-218"},"PeriodicalIF":1.1,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2017.02.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35980926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Successful pregnancies after transvenous cardiac resynchronization therapy in a woman with congenitally corrected transposition of the great arteries 先天性大动脉转位的妇女经静脉心脏再同步化治疗后妊娠成功

IF 1.1

Egyptian Heart Journal Pub Date : 2017-09-01 DOI: 10.1016/j.ehj.2017.05.002

Sana Ouali , Slim Kacem , Rim Gribaa , Elyes Neffeti , Fahmi Remedi , Essia Boughzela

引用次数: 2

Role of 2D speckle tracking echocardiography in predicting acute coronary occlusion in patients with non ST-segment elevation myocardial infarction 二维斑点跟踪超声心动图在预测非st段抬高型心肌梗死患者急性冠状动脉闭塞中的作用

IF 1.1

Egyptian Heart Journal Pub Date : 2017-06-01 DOI: 10.1016/j.ehj.2016.10.005

Viola William Keddeas, Salwa Mohammed Swelim, Ghada Kamel Selim

{"title":"Role of 2D speckle tracking echocardiography in predicting acute coronary occlusion in patients with non ST-segment elevation myocardial infarction","authors":"Viola William Keddeas, Salwa Mohammed Swelim, Ghada Kamel Selim","doi":"10.1016/j.ehj.2016.10.005","DOIUrl":"10.1016/j.ehj.2016.10.005","url":null,"abstract":"<div><h3>Background</h3><p>A substantial fraction of patients with non ST-elevation acute coronary syndrome have an occluded culprit vessel on coronary angiography. Acute coronary occlusion often results in myocardial infarction and loss of systolic function. Identification of these patients may have considerable impact on treatment and prognosis.</p></div><div><h3>Aim</h3><p>The study aims at investigating role of 2D speckle tracking echocardiography as a non-invasive predictor of acute coronary artery occlusion in patients with non ST-segment elevation myocardial infarction.</p></div><div><h3>Patients</h3><p>This study was carried on 60 patients with first attack non ST segment elevation myocardial infarction who were admitted to coronary care unit of Ain Shams University Hospitals. All patients underwent thorough history taking, full clinical examination, 12 leads surface ECG, full 2D, M-mode and Doppler echocardiographic study, two-dimensional speckle tracking strain study and coronary angiography.</p></div><div><h3>Results</h3><p>2D derived peak global longitudinal strain had a highly significant relationship in prediction of the presence of total occlusion, and also number of segments with reduced strain (functional risk area by strain) had a highly significant relationship in prediction of the presence of total occlusion. In this study, 2D derived peak longitudinal strain sensitivity and specificity were 68.9% and 77.7% respectively at a cutoff value of −15.5 while number of segments with reduced longitudinal strain sensitivity and specificity were 63.6% and 77.7% respectively at a cutoff value of 5 segments.</p></div><div><h3>Conclusion</h3><p>Both global and regional peak longitudinal systolic strain can offer accurate, feasible, and non-invasive predictor for acute coronary artery occlusion in patients with non ST elevation myocardial infarction who may benefit from early revascularization.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"69 2","pages":"Pages 103-110"},"PeriodicalIF":1.1,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2016.10.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35981060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Value of global longitudinal strain by two dimensional speckle tracking echocardiography in predicting coronary artery disease severity 二维散斑跟踪超声心动图整体纵向应变预测冠状动脉疾病严重程度的价值

IF 1.1

Egyptian Heart Journal Pub Date : 2017-06-01 DOI: 10.1016/j.ehj.2016.08.001

Hanan Radwan, Ekhlas Hussein

{"title":"Value of global longitudinal strain by two dimensional speckle tracking echocardiography in predicting coronary artery disease severity","authors":"Hanan Radwan, Ekhlas Hussein","doi":"10.1016/j.ehj.2016.08.001","DOIUrl":"10.1016/j.ehj.2016.08.001","url":null,"abstract":"<div><h3>Background</h3><p>Significant coronary artery stenosis might cause persistently impaired longitudinal left ventricle (LV) function at rest. LV global longitudinal strain (LVGLS) can be accurately assessed by 2D speckle-tracking strain echocardiography(2D-STE).</p></div><div><h3>Objective</h3><p>We aimed to evaluate the diagnostic accuracy of LV global longitudinal strain obtained by 2D-STE in prediction of severity of CAD.</p></div><div><h3>Methods</h3><p>Eighty patients with suspected stable angina pectoris were included. They underwent transthoracic echocardiography (TTE) to measure LV ejection fraction, 2-D-STE to measure GLS and coronary angiography (CA). The patients were divided into two groups: group 1 (58 patients) with significant (>70%) CAD, and group 2 (22 patients) with non-significant (<70%) CAD. Images were obtained in the apical long-axis, four-chamber, and two chamber views. Regional longitudinal systolic strain was measured in 17 myocardial segments and averaged to provide global longitudinal strain (LVGLS).</p></div><div><h3>Results</h3><p>There was significant decrease in GLS in group 1 compared to group 2 (−11.86±2.89% versus −18.65±0.79%, <em>P</em>  <0.000]. The sensitivity, specificity and accuracy of GLS for detecting significant CAD were 93.1%, 81.8%,and 90% respectively.There was a significant positive correlation between GLS and EF (<em>r</em>  =0.036).There was incremental significant decrease in GLS with increasing number of coronary vessels involved.</p></div><div><h3>Conclusion</h3><p>Measurement of global longitudinal strain using 2D speckle tracking echocardiography is sensitive and accurate tool in the prediction of severe CAD.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"69 2","pages":"Pages 95-101"},"PeriodicalIF":1.1,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2016.08.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35981059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 37

Sudden cardiac death with triple pathologies: A case report 心源性猝死合并三重病理1例

IF 1.1

Egyptian Heart Journal Pub Date : 2017-06-01 DOI: 10.1016/j.ehj.2017.02.001

R. Razuin , F. Nurquin , M.N. Shahidan , M.N. Julina

{"title":"Sudden cardiac death with triple pathologies: A case report","authors":"R. Razuin , F. Nurquin , M.N. Shahidan , M.N. Julina","doi":"10.1016/j.ehj.2017.02.001","DOIUrl":"10.1016/j.ehj.2017.02.001","url":null,"abstract":"<div><p>Sudden cardiac death in young adults may be associated with rare cardiomyopathies such as left ventricular noncompaction (LVNC) and arrhythmogenic right ventricular (ARVC) cardiomyopathies. LVNC is characterised by hypertrabeculations and deep recesses of the left ventricle. ARVC presents with thin myocardium as a result of extensive fibro-fatty infiltrations. In both conditions, death may be due to arrhythmia, thromboembolic events or heart failure. We report a case of a 21-year old athletic young man who collapsed at the futsal court right after the game. He was resuscitated but expired at the hospital after a brief admission. A week earlier, he had a similar episode of syncope and revived through cardio-pulmonary resuscitation at the site. Post mortem examination showed extensive acute myocardial infarction (AMI) involving the papillary muscles and the left ventricular wall. Features of LVNC were also observed. On top of that, the right ventricle showed patchy thin myocardium as the wall was largely comprised of fat. Histology examination confirmed the presence of AMI and massive fibro-fatty infiltrations of the right ventricle. This unfortunate young man had co-existing cardiomyopathies which is rare indeed. As he succumbed to AMI, this mechanism of death is also uncommonly associated with neither LVNC nor ARVC. In conclusion, young and physically active individuals may not be spared of sudden cardiac death. Mild and non-specific symptoms should not be taken lightly as it may be the subtle signs of cardiomyopathies.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"69 2","pages":"Pages 157-160"},"PeriodicalIF":1.1,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2017.02.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35982118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Pattern of vascular remodeling of distal reference segment after recanalization of chronic total occlusion, long-term angiographic follow-up 慢性全闭塞再通后远端参考段血管重构模式及长期血管造影随访

IF 1.1

Egyptian Heart Journal Pub Date : 2017-06-01 DOI: 10.1016/j.ehj.2016.10.002

Wassam El Din Hadad El Shafey

引用次数: 1

Atherosclerosis in chronic hepatitis C virus patients with and without liver cirrhosis 伴有和不伴有肝硬化的慢性丙型肝炎病毒患者的动脉粥样硬化

IF 1.1

Egyptian Heart Journal Pub Date : 2017-06-01 DOI: 10.1016/j.ehj.2016.10.004

Ashraf Abd El-Khalik Barakat , Fatma Mohammad Nasr , Amna Ahmed Metwaly , Sherif Morsy , Mervat Eldamarawy

{"title":"Atherosclerosis in chronic hepatitis C virus patients with and without liver cirrhosis","authors":"Ashraf Abd El-Khalik Barakat , Fatma Mohammad Nasr , Amna Ahmed Metwaly , Sherif Morsy , Mervat Eldamarawy","doi":"10.1016/j.ehj.2016.10.004","DOIUrl":"10.1016/j.ehj.2016.10.004","url":null,"abstract":"<div><h3>Background</h3><p>Chronic Hepatitis C virus (HCV) infection and liver cirrhosis may be associated with atherosclerosis and coronary artery disease (CAD). There are two phases to atherosclerosis, Subclinical and Clinical. Assessment of atherosclerosis may be started at its Subclinical phase by the evaluation of Epicardial Fat Thickness (EpFT) and Carotid Intima Thickness (CIMT).</p></div><div><h3>Aim of the study</h3><p>The aim of the study was to evaluate Clinical and Subclinical atherosclerosis in chronic HCV patients with and without liver cirrhosis by evaluating CIMT and EpFT and correlating the results with Child-Pugh functional scoring of cirrhosis as well as with ultrasound and laboratory parameters that define the severity of liver disease.</p></div><div><h3>Patients and methods</h3><p>This study involved 64 chronic HCV patients that were divided into two groups: 24 patients <em>without liver cirrhosis</em> and 40 patients <em>with liver cirrhosis</em> in addition to 20 apparently healthy volunteers serving as <em>control.</em> All of the 84 subjects were subjected to the following: Clinical evaluation; Routine Laboratory Evaluation (CBC, Liver Function Tests, Renal Function Tests, Serum electrolytes, Cholesterol, Triglycerides, HBs antigen and HCV antibody); ECG; Abdominal ultrasound; Echocardiographic evaluation of segmental wall motion abnormalities and EpFT and B-Mode Carotid ultrasonography for evaluation of CIMT.</p></div><div><h3>Results</h3><p>In the cirrhotic HCV group, the CIMT and EpFT were both significantly increased [Compared to control group (<em>p</em>  =0.000)]. In the non-cirrhotic HCV group, the CIMT and EpFT were both significantly increased compared to the control group with a <em>p</em>-value of 0.003 for CIMT and 0.048 for EpFT. The CIMT and EpFT were also positively correlated with each other (<em>r</em>  =0.001). There was a statistically significant increase in the EpFT and CIMT in Child class B patients compared to Child class A (<em>p</em>  =0.028 for EpFT) and in Child class C patients compared to Child class B patients (<em>p</em>  =0.385, <em>p</em>  =0.379, <em>p</em>  =0.378, <em>p</em>  =0.384, <em>p</em>  =0.456, <em>p</em>  =0.384, <em>p</em>  =0.378, <em>p</em>  <!--","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"69 2","pages":"Pages 139-147"},"PeriodicalIF":1.1,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2016.10.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35982116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12