Egyptian Heart Journal最新文献

Congenital atresia of left main coronary artery 先天性左主干冠状动脉闭锁

IF 1.1

Egyptian Heart Journal Pub Date : 2018-12-01 DOI: 10.1016/j.ehj.2018.10.005

Sedigheh Saedi, Hamid Reza Pouraliakbar, Homa Ghaderian, Tahereh Saedi

引用次数: 6

Risk factors for acute coronary syndrome in patients below the age of 40 years 40岁以下患者急性冠状动脉综合征的危险因素

IF 1.1

Egyptian Heart Journal Pub Date : 2018-12-01 DOI: 10.1016/j.ehj.2018.05.005

Aram J. Mirza , Abdulsalam Y. Taha , Bahar R. Khdhir

{"title":"Risk factors for acute coronary syndrome in patients below the age of 40 years","authors":"Aram J. Mirza , Abdulsalam Y. Taha , Bahar R. Khdhir","doi":"10.1016/j.ehj.2018.05.005","DOIUrl":"10.1016/j.ehj.2018.05.005","url":null,"abstract":"<div><h3>Background</h3><p>Acute coronary syndrome (ACS) refers to a spectrum of symptoms compatible with acute myocardial ischemia. Plasma markers of inflammation have been recently identified as diagnostic aid and risk predictors. The present study, conducted in Slemani Cardiac Hospital (SCH), Sulaimaniyah, Iraq aimed to recognize some risk factors for ACS in Iraqi adults younger than 40.</p></div><div><h3>Methodology</h3><p>This is a prospective case-control study of 100 patients with ACS vs. a control group of 100 healthy volunteers. The study began at 1st January 2014 and ended at 31st December 2016. All patients were subjected to full history taking, clinical examination including measurement of waist circumference and body mass index (BMI). Investigations included electrocardiography (ECG), echocardiography, full blood count, measurement of lipid profile and C-reactive protein (CRP). The patients were managed by percutaneous coronary intervention (PCI).</p></div><div><h3>Results</h3><p>The mean age of the patients was 36 years (range 28–40). Eighty-five% of patients were male. The mean BMI (29 kg/m<sup>2</sup>) and waist circumference (98 cm) of the patients were higher than the controls (24 kg/m<sup>2</sup> and 72 cm respectively). The leukocytes, lymphocytes and neutrophil counts as well as CRP in both groups were within the normal range. The most prevalent risk factor was obesity (n = 86). Other risk factors were smoking (n = 62), hypertension (n = 26), diabetes mellitus (n = 22) and positive family history of ACS (n = 24). Most patients (n = 83) had multi-vessel coronary artery disease (2–3 vessels).</p></div><div><h3>Conclusion</h3><p>ACS in young adults is an increasing health problem. Obesity was found to be the most prevalent risk factor.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"70 4","pages":"Pages 233-235"},"PeriodicalIF":1.1,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2018.05.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36818786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 36

Prevalence of early repolarization pattern and its association with sudden cardiac death and arrhythmia over one-year follow-up in an Egyptian cohort 在埃及队列中，早期复极模式的患病率及其与一年随访的心源性猝死和心律失常的关系

IF 1.1

Egyptian Heart Journal Pub Date : 2018-12-01 DOI: 10.1016/j.ehj.2018.04.001

Ahmed Tageldien Abdellah, Mohamed El Wazir, Hanan Kamal, Hesham Hegazy

{"title":"Prevalence of early repolarization pattern and its association with sudden cardiac death and arrhythmia over one-year follow-up in an Egyptian cohort","authors":"Ahmed Tageldien Abdellah, Mohamed El Wazir, Hanan Kamal, Hesham Hegazy","doi":"10.1016/j.ehj.2018.04.001","DOIUrl":"10.1016/j.ehj.2018.04.001","url":null,"abstract":"<div><h3>Background and objectives</h3><p>Early repolarization pattern (ERP) is not uncommon electrocardiography (ECG) finding and could be associated with arrhythmia and sudden cardiac death (SCD). We aimed to prospectively determine the prevalence of ERP and its association with arrhythmia and SCD during one-year follow-up in an outpatient Egyptian cohort.</p></div><div><h3>Methods</h3><p>Clinical assessment and ECG were performed to 1850 consecutive individuals presented at the outpatient clinic of Suez Canal University Hospital (SCUH). Then, the ERP group and 100 age and gender-matched ERP −ve controls had undergone echocardiography, 24-h Holter ECG and exercise stress ECG.</p></div><div><h3>Results</h3><p>ERP was found in 124 individuals (6.7%); we excluded 24 patients with structural heart disease. ERP group (No. = 100) were relatively young (80% <50 years-old) and showed male preponderance (60%). ERP frequencies were: inferolateral (50%), antero-lateral (38%), inferior (10%), and global (2%). ERP subjects were leaner than controls (BMI was 25.3 vs. 30 kg/m<sup>2</sup>, P value < 0.001) and achieved more metabolic equivalents (METS) on stress ECG (10.7 vs. 8.5 METS, P value < 0.01). Only 4% in the ERP group had horizontal/descending ST slope, while 8% had ST elevation ≥ 2 ms. No arrhythmia or SCD were reported during 1-year follow-up in both groups. Regression analysis showed that male gender, Sokolow-Lyon criteria and short QTc were significant independent predictors of ERP, P value < 0.05.</p></div><div><h3>Conclusions</h3><p>In outpatient-based Egyptian cohort, the prevalence of ERP was 6.7%, mostly the inferolateral pattern. Our ERP subjects had low-risk clinical and ECG criteria for malignant ERP. Further epidemiological studies are needed to explore the natural history of ERP.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"70 4","pages":"Pages 315-321"},"PeriodicalIF":1.1,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2018.04.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36862290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Endothelial nitric oxide synthase Glu 298 Asp (G894T) and Apolipoprotein E gene polymorphism as possible risk factors for coronary heart disease among Egyptians 内皮型一氧化氮合酶Glu 298 Asp (G894T)和载脂蛋白E基因多态性可能是埃及人冠心病的危险因素

IF 1.1

Egyptian Heart Journal Pub Date : 2018-12-01 DOI: 10.1016/j.ehj.2018.08.001

Sherif Arafa , Sherehan Abdelsalam , Abdel-Hady El-Gilany , Youssef Mohamed Mosaad , Adel Abdel-Ghaffar

{"title":"Endothelial nitric oxide synthase Glu 298 Asp (G894T) and Apolipoprotein E gene polymorphism as possible risk factors for coronary heart disease among Egyptians","authors":"Sherif Arafa , Sherehan Abdelsalam , Abdel-Hady El-Gilany , Youssef Mohamed Mosaad , Adel Abdel-Ghaffar","doi":"10.1016/j.ehj.2018.08.001","DOIUrl":"https://doi.org/10.1016/j.ehj.2018.08.001","url":null,"abstract":"<div><p>In Egypt, The prevalence of chronic heart disease (CHD) is 8.3%. It is the principal cause of death and is responsible for 22% of total mortality. The age-adjusted mortality rate is 174 per 100,000 of population. There are many studies on traditional risk factors and CHD in Egypt but the study of novel risk factors is deficient.</p></div><div><h3>Objectives</h3><p>The aim of the present case control study was to investigate the relation between CHD susceptibility and <em>Endothelial Nitric Oxide Synthase</em> (eNOS) Glu 298 Asp (G894T) and <em>Apolipoprotein E</em> (ApoE) gene polymorphism in a cohort of Egyptian individuals.</p></div><div><h3>Methods</h3><p>Genotyping of eNOS (Glu298Asp) and Apo E genes polymorphisms were done using polymerase chain reaction-restriction fragment length polymorphism (PCR–RFLP) method for 100 CHD cases and 100 age and sex matched healthy controls.</p></div><div><h3>Results</h3><p>A statistically significant association was observed between GT and TT genotypes of endothelial nitric oxide synthase gene with CHD with OR = 2.03 and 3.5; respectively. Also, carriers of E4 allele and especially E3/E4 genotype were at higher risk of CHD with OR = 3.3 for both. Significant association was also observed between the presence of combined GTE3E4 genotype and CHD with OR = 6.6.</p></div><div><h3>Conclusion</h3><p>GT and TT genotypes of endothelial nitric oxide synthase gene, E3/E4 genotype of Apo E gene polymorphism and combined GTE3E4 genotype can be considered risk factors for the development of CHD among Egyptians.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"70 4","pages":"Pages 393-401"},"PeriodicalIF":1.1,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2018.08.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91770357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

The predictive value of R-wave peak time on no-reflow in patients with ST-elevation myocardial infarction treated with a primary percutaneous coronary intervention 经皮冠状动脉介入治疗st段抬高型心肌梗死患者无血流再灌注时r波峰值时间的预测价值

IF 1.1

Egyptian Heart Journal Pub Date : 2018-12-01 DOI: 10.1016/j.ehj.2018.07.006

Ahmed Bendary , Mohamed El-Husseiny , Tarek Aboul Azm , Ahmed Abdoul Moneim

{"title":"The predictive value of R-wave peak time on no-reflow in patients with ST-elevation myocardial infarction treated with a primary percutaneous coronary intervention","authors":"Ahmed Bendary , Mohamed El-Husseiny , Tarek Aboul Azm , Ahmed Abdoul Moneim","doi":"10.1016/j.ehj.2018.07.006","DOIUrl":"10.1016/j.ehj.2018.07.006","url":null,"abstract":"<div><h3>Background</h3><p>Coronary no-reflow (NR) is a dreadful complication of primary percutaneous coronary intervention (pPCI) that is seen in nearly 50% of cases. A great effort is being done to discover simple tools that could predict such a complication. We aimed primarily to study the predictive power of R-wave peak time (RWPT) on NR.</p></div><div><h3>Methods</h3><p>From October 2017 to March 2018, we enrolled 123 patients with STEMI treated with pPCI at Benha University Hospital and National Heart Institute. We measured RWPT from infarct-related artery (IRA) leads and assessed the development of NR in all finally included 100 patients (after exclusions).</p></div><div><h3>Results</h3><p>Based on occurrence of NR, patients were divided into 2 groups; Group I (n = 39) with NR and group II (n = 61) without NR. Smoking, DM, HTN, longer reperfusion times and higher thrombus burden were significantly associated with NR. Both pre- and postprocedural RWPT were significantly higher in group I than Group II. Preprocedural RWPT > 46 ms predicted NR with a sensitivity and specificity of 79.5% and 86.9% respectively (AUC 0.891, 95% CI 0.82–0.962, P < 0.001). In adjusted multivariate analysis, preprocedural RWPT was found to be among independent predictors for NR (OR: 26.2, 95% CI: 6.5–105.1, P < 0.001). The predictive power of preprocedural RWPT was statistically non-inferior to ST-resolution (STR)% (difference between area under curves = 0.029, P = 0.595).</p></div><div><h3>Conclusion</h3><p>RWPT is strongly associated with and significantly predicts the development of NR. This association was statistically non-inferior to the well-known association between STR% and NR.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"70 4","pages":"Pages 415-419"},"PeriodicalIF":1.1,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2018.07.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36819656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of high flow arteriovenous fistula on cardiac function in hemodialysis patients 高流量动静脉瘘对血液透析患者心功能的影响

IF 1.1

Egyptian Heart Journal Pub Date : 2018-12-01 DOI: 10.1016/j.ehj.2018.10.007

Mohamed Ayman Saleh , Wael Mahmoud El Kilany , Viola William Keddis , Tamer Wahid El Said

{"title":"Effect of high flow arteriovenous fistula on cardiac function in hemodialysis patients","authors":"Mohamed Ayman Saleh , Wael Mahmoud El Kilany , Viola William Keddis , Tamer Wahid El Said","doi":"10.1016/j.ehj.2018.10.007","DOIUrl":"10.1016/j.ehj.2018.10.007","url":null,"abstract":"<div><h3>Background</h3><p>Vascular access for hemodialysis (HD) with an inappropriately high flow may underlie the onset of high output heart failure (HOHF).</p><p>The aim of this study was to determine the prevalence of high flow access (HFA) in chronic HD patients, and to determine its effects on cardiac functions.</p></div><div><h3>Methods</h3><p>This cross sectional study was conducted on 100 chronic hemodialysis patients through arteriovenous fistula (AVF). The study cohort was subdivided into 2 groups based on AVF flow: <strong>Group A</strong> (Non-HFA group with Qa < 2000 ml/min), and <strong>Group B</strong> (HFA group with Qa ≥ 2000 ml/min). AVF flow (Qa) was assessed using Color Doppler ultrasonography. Transthoracic echocardiography was performed for all patients to assess cardiac dimensions and functions.</p></div><div><h3>Results</h3><p>Prevalence of HFA among study population was 24%. Mean AVF Qa was 958.63 ± 487.35 and 3430.13 ± 1256.28 ml/min, for group A and B respectively. The HFA group demonstrated a significant dilatation in LV dimensions and volumes and significantly larger LA volume as compared to non-HFA group. A significantly lower LV ejection fraction [EF] was also observed in group B with a mean value of 57.32 ± 6.19% versus 62.90 ± 5.76%. A significant association between HFA group and high Qa/cardiac output (CO) ratio (≥20%) was also observed.</p></div><div><h3>Conclusion</h3><p>HFA is a prevalent hemodialysis vascular access problem. HFA was associated with dilated LV dimensions, impaired LV systolic function. High Qa/CO ratio (≥20%) was an independent predictor of high output heart failure (HOHF) in our study population.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"70 4","pages":"Pages 337-341"},"PeriodicalIF":1.1,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2018.10.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36820707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Left atrial deformation analysis as a predictor of severity of coronary artery disease 左心房变形分析作为冠状动脉疾病严重程度的预测因子

IF 1.1

Egyptian Heart Journal Pub Date : 2018-12-01 DOI: 10.1016/j.ehj.2018.09.004

Khaled Mohamed Said , Ahmed Ibrahim Nassar , Ahmed Fouad , Ali A. Ramzy , Mustafa Fayed Fadle Abd Allah

{"title":"Left atrial deformation analysis as a predictor of severity of coronary artery disease","authors":"Khaled Mohamed Said , Ahmed Ibrahim Nassar , Ahmed Fouad , Ali A. Ramzy , Mustafa Fayed Fadle Abd Allah","doi":"10.1016/j.ehj.2018.09.004","DOIUrl":"10.1016/j.ehj.2018.09.004","url":null,"abstract":"<div><h3>Background</h3><p>Two-dimensional (2D) speckle-tracking strain imaging is a novel method for assessment of regional myocardial deformation that uses tracking of acoustic speckles or kernels rather than Doppler myocardial velocities. It has been suggested that Left atrial (LA) strain as measured by 2D speckle tracking can be used to evaluate dynamic LA function.</p></div><div><h3>Objective</h3><p>To study the relation between left atrial deformation and the severity of coronary artery stenosis in patients with stable coronary artery disease (CAD).</p></div><div><h3>Study design</h3><p>30 patients with stable coronary artery disease (SCAD) with coronary artery stenosis (>50%) who were admitted for elective coronary angiography at Ain Shams University hospitals and AlAzhar University hospitals were included in the study. Measurements of conventional echocardiographic parameters as well as LA strain and strain rate parameters were obtained, Syntax (SX) score was calculated for all patients.</p></div><div><h3>Results</h3><p>Patients were categorized into 3 groups: low Syntax score of <23 (Group I), moderate syntax score 23–32 (Group II) and high syntax score of ≥33 (Group III). Peak atrial longitudinal strain (PALS) (Group I: 29.80 ± 4.48, Group II: 22.44 ± 1.42, Group III: 19.53 ± 4.46; p < 0.001) and Peak atrial contraction strain (PACS) (Group I: 13.43 ± 4.05, Group II: 10.84 ± 2.47, Group III: 7.19 ± 0.71; p < 0.022) were significantly lower in high syntax group. Significant negative correlation was found between SX score level and LA strain parameters (PALS and PACS) (r = 0.861; p < 0.001).</p></div><div><h3>Conclusion</h3><p>Left atrial deformation analysis by 2D Speckle tracking Doppler Echocardiography can predict the severity of coronary affection in patients with stable CAD.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"70 4","pages":"Pages 353-359"},"PeriodicalIF":1.1,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2018.09.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36820709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Clinical safety profile of ticagrelor compared to clopidogrel in 1208 patients: Real world evidence 1208例替格瑞洛与氯吡格雷比较的临床安全性:真实世界证据

IF 1.1

Egyptian Heart Journal Pub Date : 2018-12-01 DOI: 10.1016/j.ehj.2018.05.002

Viveka Kumar , Vivek Kumar , Kajal Kumari , K.K. Talwar , Divya Prasad , Sunil Agarwal , M.S. Yadav , Hamed Bashir , Suman Jatain , S.K. Gupta

{"title":"Clinical safety profile of ticagrelor compared to clopidogrel in 1208 patients: Real world evidence","authors":"Viveka Kumar , Vivek Kumar , Kajal Kumari , K.K. Talwar , Divya Prasad , Sunil Agarwal , M.S. Yadav , Hamed Bashir , Suman Jatain , S.K. Gupta","doi":"10.1016/j.ehj.2018.05.002","DOIUrl":"10.1016/j.ehj.2018.05.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Dual antiplatelet treatment is recommended by current clinical practice guidelines for patients undergoing PCI. The PLATO trial showed superiority of ticagrelor to clopidogrel in reducing the rate of death from vascular causes, myocardial infarction and stroke without increase in the rate of overall major bleeding in ACS patients. However, real world evidence in Indian patients is limited. The objective of this study is to compare safety profile of ticagrelor with clopidogrel in real world settings.</p></div><div><h3>Methodology</h3><p>In this single centered retrospective observational study, a total of 1208 serial patient records undergoing PCI (ACS and stable angina patients as well) treated with Ticagrelor or Clopidogrel were collected and analyzed to look into in hospital outcomes. We excluded the patient’s data that were incomplete.</p></div><div><h3>Results</h3><p>In total of 1208 patients, 604 patients received ticagrelor and similarly 604 patient received clopidogrel. No significant differences in the rates of major life threatening bleeding and any major bleeding were observed between ticagrelor and clopidogrel group (0.2% (n = 1) vs. 0.7% (n = 4), p = 0.18 and 2.8% (n = 17) vs. 3% (n = 18), p = 0.86 respectively). There was increase in minor bleeding rate with ticagrelor compared to clopidogrel (21.4% & 13.6%, p = 0.00).</p></div><div><h3>Conclusion</h3><p>In the real world settings, patients undergoing PCI treated with ticagrelor showed similar safety profile compared to clopidogrel but with increase in minor bleeding rate. The observed results were in alignment with PLATO clinical trial.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"70 4","pages":"Pages 375-378"},"PeriodicalIF":1.1,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2018.05.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36820713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Effect of exercise training on heart rate recovery in patients post anterior myocardial infarction 运动训练对前路心肌梗死患者心率恢复的影响

IF 1.1

Egyptian Heart Journal Pub Date : 2018-12-01 DOI: 10.1016/j.ehj.2018.04.007

Ahmed Elshazly, Hazem Khorshid, Hany Hanna, Ammar Ali

{"title":"Effect of exercise training on heart rate recovery in patients post anterior myocardial infarction","authors":"Ahmed Elshazly, Hazem Khorshid, Hany Hanna, Ammar Ali","doi":"10.1016/j.ehj.2018.04.007","DOIUrl":"10.1016/j.ehj.2018.04.007","url":null,"abstract":"<div><h3>Background</h3><p>Regular exercise training has been shown to reduce mortality, improve functional capacity; and control the risk factors in myocardial infarction (MI) patients. Heart rate recovery (HRR) is a strong independent mortality predictor in patients with previous MI.</p></div><div><h3>Aim</h3><p>The main objective of this study was to investigate the impact of exercise training on heart rate recovery in patients post anterior myocardial infarction.</p></div><div><h3>Methods</h3><p>We recruited patients one month after having anterior MI who were referred to cardiac rehabilitation (CR) clinic in Ain Shams University hospital between October 2016 and July 2017. All the patients participated in exercise training sessions 3 times a week for 12 weeks. Symptom limited treadmill exercise test was done before and after exercise training program to calculate heart rate recovery in 1st minute (HRR1) and 2nd minute (HRR2).</p></div><div><h3>Results</h3><p>A total of 50 patients, including 44 (88%) males, completed the exercise training program. The mean age was 51 years. Statistically significant improvement in HRR1 and HRR2 was observed (p value <0.001) after completion of exercise based cardiac rehabilitation program. Significant improvement in resting heart rate was also observed (p value <0.001). Moreover, metabolic equivalent (METs) and HR reserve were improved significantly (p value <0.001). No statistically significant changes were observed in resting systolic and diastolic blood pressures and maximum HR (p value = 0.95, 0.76 and 0.31 respectively).</p></div><div><h3>Conclusion</h3><p>Exercise training improves HRR, resting HR, METs and HR reserve in post anterior MI patients.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"70 4","pages":"Pages 283-285"},"PeriodicalIF":1.1,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2018.04.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36862285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

High intensity interval training exercise as a novel protocol for cardiac rehabilitation program in ischemic Egyptian patients with mild left ventricular dysfunction 高强度间歇训练运动作为心脏康复计划的新方案缺血性埃及患者轻度左心室功能障碍

IF 1.1

Egyptian Heart Journal Pub Date : 2018-12-01 DOI: 10.1016/j.ehj.2018.07.008

A.M. Abdelhalem , A.M. Shabana , A.M. Onsy , A.E. Gaafar

{"title":"High intensity interval training exercise as a novel protocol for cardiac rehabilitation program in ischemic Egyptian patients with mild left ventricular dysfunction","authors":"A.M. Abdelhalem , A.M. Shabana , A.M. Onsy , A.E. Gaafar","doi":"10.1016/j.ehj.2018.07.008","DOIUrl":"10.1016/j.ehj.2018.07.008","url":null,"abstract":"<div><h3>Background</h3><p>Exercise-based Cardiac rehabilitation (CR) plays a major role in reducing mortality and morbidity in patients with coronary artery disease (CAD). The standard protocol is usually of moderate intensity exercise. High-intensity interval training (HIIT) consists of alternating periods of intensive aerobic exercise with periods of passive or active moderate/mild intensity recovery.</p></div><div><h3>Aim</h3><p>This study aimed to assess HIIT program for ischemic patients attending CR after percutaneous coronary intervention (PCI) who have mild left ventricular dysfunction and to compare its effect on the functional capacity and quality of life with standard exercise CR program.</p></div><div><h3>Patients and methods</h3><p>Our study included 40 patients with documented CAD, who participated in the outpatient CR program in Ain Shams University hospital (Al-Demerdash Hospital) divided into two equal groups, each included 20 patients. Group A included the patients who underwent standard cardiac rehabilitation program, while group B joined the high intensity interval training exercise protocol.</p></div><div><h3>Results</h3><p>Groups A and B showed significant improvement in all items of comparison; especially functional capacity, lipid profile and quality of life. Group B showed better improvements in the emotional well-being items of QOL parameters.</p></div><div><h3>Conclusion</h3><p>We emphasize the positive effects of exercise-based CR program on patients with CAD and mild left ventricular dysfunction after PCI. The novel high intensity cardiac training proved to be safe and at least as beneficial as the standard moderate intensity cardiac training protocols, with better quality of life improvement.</p></div>","PeriodicalId":44962,"journal":{"name":"Egyptian Heart Journal","volume":"70 4","pages":"Pages 287-294"},"PeriodicalIF":1.1,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehj.2018.07.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36862286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12