{"title":"Response to \"Cryptococcal immune reconstitution inflammatory syndrome: Cutaneous clues to disseminated cryptococcosis in a human immunodeficiency virus patient coinfected with tuberculosis on antiretroviral therapy\".","authors":"Sharang Gupta","doi":"10.4103/ijstd.ijstd_18_26","DOIUrl":"10.4103/ijstd.ijstd_18_26","url":null,"abstract":"","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"78-79"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trends of syphilis before, during, and after the COVID-19 pandemic in central India: A retrospective study.","authors":"Bhagyashree Babanrao Supekar, Suyash Singh Tomar, Samruddhi Naresh Chopkar, Jayesh Ishwardas Mukhi, Pallavi Rajesh Mishra, Pallavi Jagdish Yede","doi":"10.4103/ijstd.ijstd_94_25","DOIUrl":"10.4103/ijstd.ijstd_94_25","url":null,"abstract":"<p><strong>Background: </strong>Syphilis is a sexually transmitted disease that varies in presentation according to the stage of the disease. Susceptibility to penicillin contributed to the near elimination of the disease during the 1990s to 2000 period. Recently, there have been reports of the re-emergence of syphilis from all parts of the world.</p><p><strong>Aim: </strong>To study the clinical presentation and trends of syphilis.</p><p><strong>Materials and methods: </strong>A retrospective study was conducted from January 2013 to December 2024. All clinically and/or serologically diagnosed cases of syphilis were included in the study. Medical records of all the patients attending the sexually transmitted infection clinic were analyzed concerning age, sex, clinical presentation, and laboratory investigations. Statistical analysis was done using mean, median, and proportion.</p><p><strong>Results: </strong>A total of 260 cases with syphilis were enrolled. The male-to-female ratio was 5.53:1. The most common stage of presentation was latent syphilis (45.6%). The most common age group affected was 21-30 years. Out of the total cases, 2.7% of cases were pregnant females, 14.18% were human immunodeficiency virus (HIV) positive, and 95 cases were men who have sex with men cases. Only two cases of congenital syphilis were detected.</p><p><strong>Conclusion: </strong>A resurgence of syphilis cases has been observed in the last 3 years, with latent syphilis contributing to the majority of cases. Possible factors attributed to this surge include promiscuous sexual behavior, HIV coinfection, male having sex with male, and early adolescent sexual exposure. The sudden rise in latent syphilis cases is a warning sign of resurgence in India, as it signifies the persistence of syphilis in the subclinical phase in the community.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"16-21"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic efficacy of cryotherapy in genital warts: A case series with patient-reported outcomes.","authors":"Chittarvu Karishni, Muske Samskruthi, Muthu Priya, Chintagunta Sudha Rani","doi":"10.4103/ijstd.ijstd_158_25","DOIUrl":"10.4103/ijstd.ijstd_158_25","url":null,"abstract":"<p><p>Genital warts are common benign lesions caused predominantly by human papillomavirus types 6 and 11 and are associated with significant psychosocial morbidity. Cryotherapy remains a widely used ablative modality, yet data on patient-reported outcomes in real-world settings remain limited. To evaluate the therapeutic efficacy, safety profile, and patient-reported outcomes of cryotherapy in the management of genital warts. A case series of seven treatment-naive patients with clinically and dermoscopically confirmed genital warts was analyzed. All patients underwent cryotherapy with a cryoprobe using two freeze-thaw cycles per session at 2-week intervals. Pain was assessed using the Visual Analogue Scale (VAS), and quality-of-life changes were measured using the Dermatology Life Quality Index (DLQI) before treatment and two weeks after the final session. Complete or near-complete clearance was achieved in 71.4% of patients after 1-2 sessions. Adverse effects occurred in 57.1%, predominantly procedural pain and transient hypopigmentation. DLQI scores improved markedly among patients with complete clearance, indicating significant psychosocial recovery, whereas incomplete responders-particularly immunocompromised individuals-showed minimal improvement. Recurrence occurred in 14% of cases. Cryotherapy is a safe, cost-effective, and efficacious first-line treatment for genital warts, especially in immunocompetent patients. Incorporating patient-reported outcomes such as DLQI and VAS provides a holistic assessment of therapeutic success and should be adopted routinely.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"36-38"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Keshav Yadav, Parth Rathi, Prakhar Srivastava, Niti Khunger
{"title":"From anxiety to clarity: Role of dermoscopy in diagnosing pearly penile papules.","authors":"Keshav Yadav, Parth Rathi, Prakhar Srivastava, Niti Khunger","doi":"10.4103/ijstd.ijstd_154_25","DOIUrl":"10.4103/ijstd.ijstd_154_25","url":null,"abstract":"","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"70-72"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to the article entitled as \"Venereophobia - A comprehensive review\".","authors":"Murugan Sankaranantham","doi":"10.4103/ijstd.ijstd_143_25","DOIUrl":"10.4103/ijstd.ijstd_143_25","url":null,"abstract":"","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"70"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum: Human papillomavirus vaccine use in clinical practice - What dermatologists should know as health care providers.","authors":"","doi":"10.4103/ijstd.ijstd_76_26","DOIUrl":"10.4103/ijstd.ijstd_76_26","url":null,"abstract":"<p><p>[This corrects the article on p. 7 in vol. 46, PMID: 40546358.].</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"87"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148363003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From The Desk of Editor-in-chief.","authors":"Krina Patel","doi":"10.4103/ijstd.ijstd_55_26","DOIUrl":"https://doi.org/10.4103/ijstd.ijstd_55_26","url":null,"abstract":"","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"1"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shaziya Kalam, P K Ashwini, Jayadev B Betkerur, Veeranna Shastry
{"title":"Conundrum of sexually transmitted infections - One patient, many diseases.","authors":"Shaziya Kalam, P K Ashwini, Jayadev B Betkerur, Veeranna Shastry","doi":"10.4103/ijstd.ijstd_163_25","DOIUrl":"10.4103/ijstd.ijstd_163_25","url":null,"abstract":"<p><p>Multiple sexually transmitted infections (STIs) can occur in a single patient, more so in immunocompromised and rarely in immunocompetent patients. We report a case of concurrent syphilitic gumma, condyloma accuminatum, and herpes genitalis in an immunocompetent patient, which resolved with specific treatment. STIs are linked to human behavior. Identification of these risk groups and providing treatment and counseling becomes important in control of STIs.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"55-57"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Venkataravikanth Eddula, V Sudhakar Babu, C Sravana Deepthi, Sirshendu Chaudhuri, K H Sneha
{"title":"Dual burden of tuberculosis and human immunodeficiency virus: Outcomes and implications from Chittoor district, Andhra Pradesh.","authors":"Venkataravikanth Eddula, V Sudhakar Babu, C Sravana Deepthi, Sirshendu Chaudhuri, K H Sneha","doi":"10.4103/ijstd.ijstd_72_25","DOIUrl":"10.4103/ijstd.ijstd_72_25","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection remain a significant public health challenge, particularly in resource-limited settings. This study investigates the prevalence, clinical characteristics, and treatment outcome of TB-HIV coinfected patients in Chittoor, Andhra Pradesh, India.</p><p><strong>Methodology: </strong>A retrospective cross-sectional observational study was conducted using hospital records in an antiretroviral therapy (ART) Centre of a tertiary care hospital from October 2021 to September 2023. Among 3383 registered HIV patients, 129 (3.8%) were diagnosed with TB. Clinical data, diagnostic methods, and treatment outcomes were analyzed.</p><p><strong>Results: </strong>Most patients were males (62.0%), with a mean age of 39.7 years. Pulmonary TB was the most common type (93.0%), and 58.1% of cases were microbiologically confirmed. The median baseline and follow-up CD4 counts were 309 and 430 cells/mm<sup>3</sup>, respectively. TB treatment adherence was 74.6%, while 24.0% defaulted, contributing to 84.4% of the reported deaths. Incomplete isoniazid preventive therapy was a significant predictor of treatment default and mortality.</p><p><strong>Conclusion: </strong>Despite progress in ART coverage and TB diagnosis, challenges in treatment adherence and mortality reduction persist. Strengthening diagnostic infrastructure, adherence strategies, and integrated TB-HIV care is crucial to improve outcomes in co-infected populations.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"22-26"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}