Indian Journal of Sexually Transmitted Diseases and AIDS最新文献

{"title":"Increased Post-Covid 2019 burden of gonorrhea at a tertiary care hospital in Delhi: Cause for concern.","authors":"Deepika Pandhi, Vishal Pal, Bharti Aggarwal, Archana Singal","doi":"10.4103/ijstd.ijstd_15_25","DOIUrl":"10.4103/ijstd.ijstd_15_25","url":null,"abstract":"<p><strong>Introduction: </strong>Gonorrhea caused by <i>Neisseria gonorrhoeae</i> is an sexually transmitted infection (STI), particularly observed among young people between 15 and 24 years of age. Gonorrhoea remains a significant public health problem due to its recent resurgence and the emergence of antibiotic resistance. Understanding the epidemiological patterns is crucial for effectively addressing the burden of the disease and developing targeted interventions.</p><p><strong>Methods: </strong>This was a single center and retrospective study conducted over 6 years from March 2018 to March 2024. The case records of 69 patients of gonorrhea (Group A [precoronavirus diseases 2019 (COVID-19); <i>n</i> = 11] and Group B [post-COVID-19; <i>n</i> = 58]) who attended STI clinic of a tertiary care center were analyzed. Gonorrhea had been diagnosed based on the clinical presentation and Gram-stained smear examination.</p><p><strong>Results: </strong>The average age of patients in Group A and B was comparable (31.1 and 31.3 respectively). Males outnumbered the females, but remarkably 36.2% female patients had gonorrhea. The frequency of sexual encounter per month was significantly higher in Group B (mean 3.76) as compared to Group A (1.36; <i>P</i> = 0.0002). In Group B, seven patients were males who have sex with males (MSM). Marital status, educational, occupation, age of first sexual contact, and sexual orientation were comparable in both the groups. Pharyngeal and rectal involvement was seen in 2 and 1 patients, respectively. Five patients had reinfection and three patients had lack of response with suspected resistance to ceftriaxone. Partner screening was possible in only 8.6% of the patients in post-COVID-19 group.</p><p><strong>Discussion: </strong>In this study, we found a higher number of gonorrhea patients (58) during the post-COVID-19 era. This may be attributable to higher number of partners, contact with commercial sex workers and increased frequency of sexual contact per month. Extragenital gonorrhea was also found in MSM patients. Decriminalization of homosexuality and easy access to digital media makes it easy to find partners online, but this has a hazardous impact due to casual sexual encounters, risky sexual behavior, condomless sex, increased number of sexual partner, and importantly difficulty in partner tracing.</p><p><strong>Conclusion: </strong>Our study indicates, resurgence of gonorrhea in post-COVID-19 period and emergence of cases with lack of adequate treatment response, thereby, emphasizing the need for increased surveillance.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"27-31"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Masson's tumor masquerading as a genital ulcer: A vascular impostor in an unlikely site.","authors":"Aastha Choudhary, Rachita Misri, Meenakshi Batrani, Anshuman Dash","doi":"10.4103/ijstd.ijstd_178_25","DOIUrl":"10.4103/ijstd.ijstd_178_25","url":null,"abstract":"<p><p>Intravascular papillary endothelial hyperplasia (IPEH), or Masson's tumor, is a rare benign vascular lesion, seldom described in the genital region. We report a 20-year-old male presenting with a painless penile ulcer initially mistaken for a sexually transmitted infection. Histopathology showed characteristic papillary endothelial proliferation within vessel lumina, with no atypia. Complete excision led to a favorable outcome with no recurrence. This report emphasizes IPEH as an important mimic of genital ulcer disease.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"63-65"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudo Groove's sign: A novel finding in cutaneous tuberculosis.","authors":"Kiran, K Sushmitha, M Ramesh Bhat, Michelle Serene Fernandes, Sonal Fernandes, Nagbhushan Hegde, Jacintha Martis, S Sneha","doi":"10.4103/ijstd.ijstd_125_25","DOIUrl":"10.4103/ijstd.ijstd_125_25","url":null,"abstract":"<p><p>The \"Grooves Sign\" was initially described in relation to lymphogranuloma venereum, where the enlargement of both inguinal and femoral lymph nodes creates a groove between them, caused by the attachment of the inguinal ligament at the center. Subsequently, the term \"Pseudo Grooves Sign\" was coined in relation to donovanosis, wherein subcutaneous swelling on both sides of Poupart's ligament results in a groove. In this report, we describe the presence of the \"Pseudo Grooves Sign\" in a case of cutaneous tuberculosis, emphasizing the significance of considering all other potential diagnoses when dealing with such scenarios.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"47-49"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between human papillomavirus subtype and persistence or recurrence of condyloma acuminata: A systematic review and meta-analysis.","authors":"Mohammad Syafri Syahruddin, Idrianti Idrus, Khairuddin Djawad","doi":"10.4103/ijstd.ijstd_197_25","DOIUrl":"10.4103/ijstd.ijstd_197_25","url":null,"abstract":"<p><p>Condyloma acuminata (CA), a human papillomavirus (HPV)-linked sexually transmitted infection, frequently persists or recurs, especially with high-risk (HR) strains. This systematic review and meta-analysis examine how specific HPV subtypes influence CA persistence/recurrence. We searched four databases (Science Direct, PubMed, Cochrane/CENTRAL, and Google Scholar) for relevant observational studies and randomized controlled trials (2005-2025). All meta-analytic statistics were processed using RevMan 5.4.1. Eight studies comprising a total of 1,070 subjects analyzed in this review demonstrated variable findings regarding the association between HPV subtypes and the persistence or recurrence of CA. The distribution of HPV types showed wide variability. The identified low-risk HPV (LR-HPV) subtypes included types 2, 6, 11, 27, 40, 42, 43, 44, 46, and 61, while the HR subtypes were 16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 54, 56, 58, 59, 61, 66, 68, 69, and 70. In addition, 413 cases were reported without specific HPV type information from the studies analyzed. The meta-analysis showed a nonsignificant trend where HR HPV was linked to greater recurrence/persistence than LR-HPV (pooled OR 1.45, 95% CI: 0.81-2.61; <i>P</i> = 0.22, I² =65%). To conclude, HPV subtype is not significantly associated with the recurrence or persistence of CA.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"8-15"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Floret pattern of primary chancres: An atypical manifestation of syphilis.","authors":"Akshay Meena, Sree Yazhini Ramar, Malathi Munisamy","doi":"10.4103/ijstd.ijstd_133_25","DOIUrl":"https://doi.org/10.4103/ijstd.ijstd_133_25","url":null,"abstract":"","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"83"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on clinical types of warts and its correlation with human papillomavirus genotypes.","authors":"Shivani Chaturvedi, Vineet Relhan, Kapil Arora, Tarang Goyal","doi":"10.4103/ijstd.ijstd_103_25","DOIUrl":"10.4103/ijstd.ijstd_103_25","url":null,"abstract":"<p><strong>Context: </strong>Human papilloma viruses (HPVs) are small, nonenveloped, double-stranded DNA viruses that infect mucosal and cutaneous epithelia. Cutaneous warts are typically associated with HPV types 1, 2, 3, 4, 7, 10, 27, 41, 57, 60, 63, and 65. Anogenital warts are linked to low-risk (types 6, 11) and high-risk HPV genotypes (types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59).</p><p><strong>Aim: </strong>This study aims to evaluate the types and clinical presentation of warts and correlate them with HPV genotypes using polymerase chain reaction (PCR)-based detection methods.</p><p><strong>Settings and design: </strong>A hospital-based prospective study conducted in the Department of Dermatology, Venereology, and Leprology (DVL) at Muzaffarnagar Medical College, Muzaffarnagar.</p><p><strong>Subjects and methods: </strong>Fifty patients aged 10-70 years presenting with warts at the DVL Outpatient Department were enrolled. Demographic and clinical data were collected. Wart samples underwent biopsy, histopathological examination, and HPV genotyping via PCR.</p><p><strong>Statistical analysis used: </strong>Data entry using Microsoft Excel analyzed with SPSS version 21. The data were obtained, coded, and entered into Epidata.</p><p><strong>Results: </strong>HPV DNA was detected in 70% of patients. Genotypes 6 (45.7%) and 11 (22.86%) were the most common and frequently associated with genital warts (58%). Most lesions were dome-shaped (0-2 cm). Contact with infected individuals was reported by 74%, and 44% had warts for 2-4 months.</p><p><strong>Conclusions: </strong>Warts are common in young adults (20-30 years) with equal gender distribution. Genital warts were the predominant type, with HPV 6 and 11 being the most frequent strains. The findings emphasize the importance of early detection and public health intervention.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"32-35"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bullous pemphigoid in a person living with human immunodeficiency virus: An association or coincidence.","authors":"Ishita Kaushal, Anubha Dev, Debajyoti Chatterjee, Rahul Mahajan, Sanjeev Handa, Dipankar De","doi":"10.4103/ijstd.ijstd_18_25","DOIUrl":"10.4103/ijstd.ijstd_18_25","url":null,"abstract":"<p><p>Bullous pemphigoid (BP) is known to be associated with various comorbidities such as diabetes mellitus and neurological disorders. However, its association with human immunodeficiency virus (HIV) has been occasionally reported. We hereby report a case of a middle-aged female with BP as well as HIV infection and explore the association between the two conditions.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"39-41"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermoscopic features of Bowenoid papulosis: A case report and brief review.","authors":"Shagufta Rather, Misbah Qayoom","doi":"10.4103/ijstd.ijstd_160_25","DOIUrl":"10.4103/ijstd.ijstd_160_25","url":null,"abstract":"<p><p>Bowenoid papulosis (BP) is a rare human papillomavirus-induced intra-epithelial neoplasia that typically presents as multiple pigmented or erythematous papules in the anogenital region of sexually active young adults. Despite its low malignant potential (<1% risk of progression to invasive squamous cell carcinoma), prompt recognition and management remain essential to mitigate this risk. Dermoscopy can be a valuable noninvasive diagnostic adjunct, aiding differentiation from mimickers like genital warts and pigmented Bowen's disease. However, literature on dermoscopic features of BP remains limited to a few case reports. This case highlights the role of dermoscopy in the early identification of BP and also reviews the dermoscopic features documented in the literature, intending to promote the more frequent use of dermoscopy in its clinical diagnosis.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"52-55"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is the great imitator back? A case series on atypical presentation of primary syphilis as multiple herpetiform ulcers.","authors":"Renu Kandpal, Vikas Pathania, Gyanesh Rathore, Arun Kumar Sharma","doi":"10.4103/ijstd.ijstd_167_25","DOIUrl":"10.4103/ijstd.ijstd_167_25","url":null,"abstract":"<p><p>Syphilis is a systemic human infection which is caused by <i>Treponema pallidum</i>, a spirochete. It is an obligate human pathogen, which is renowned for its immune-evasiveness. It is one of the most common sexually transmitted infection that present as genital ulcer disease. The classic ulcerative lesion of syphilis is referred to as a painless hard chancre. This description can mislead inexperienced physicians when syphilis presents atypically. Traditionally, syphilis has been referred to as \"the great imitator\" owing to its myriad and multisystem involvement. We present a case series of eleven patients who presented with multiple, polysized or herpetiform ulcers over the genitalia and in whom the diagnosis of syphilis was eventually confirmed.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"57-60"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Herpes zoster in diverse immunocompromised populations: A case series.","authors":"R Amudha, V Sushmitha, M K Karthik, S Shibe Ganesh, M Ramya","doi":"10.4103/ijstd.ijstd_75_25","DOIUrl":"10.4103/ijstd.ijstd_75_25","url":null,"abstract":"<p><p>Herpes zoster (HZ), caused by reactivation of the varicella-zoster virus, is often linked to immunosuppression and can present atypically. This case series describes nine patients: five human immunodeficiency virus (HIV)-positive adults with reduced CD4 counts (380-458 cells/mm³) and two children on immunosuppressive therapy for leukemia. Adult cases showed severe pain and lesions across multiple dermatomes, with facial or thoracic involvement. Two had high-risk sexual behavior, and one had recurrent episodes. The children presented with severe pain and vesicular lesions; one had noncontiguous dermatomal involvement. The findings underscore the role of immunosuppression, particularly HIV and leukemia therapy, in atypical HZ presentations.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"47 1","pages":"41-45"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}