THERAPEUTISCHE UMSCHAU最新文献_第4页

[Acute high-altitude illnesses - Definition, Prophylaxis, Therapy]. [急性高原疾病-定义，预防，治疗]。

IF 0.2

THERAPEUTISCHE UMSCHAU Pub Date : 2025-12-01 DOI: 10.23785/TU.2025.06.007

Dinah Hertig, Mona Lichtblau, Michael Furian, Silvia Ulrich, Laura Mayer

{"title":"[Acute high-altitude illnesses - Definition, Prophylaxis, Therapy].","authors":"Dinah Hertig, Mona Lichtblau, Michael Furian, Silvia Ulrich, Laura Mayer","doi":"10.23785/TU.2025.06.007","DOIUrl":"10.23785/TU.2025.06.007","url":null,"abstract":"Introduction: Acute altitude illnesses are significant can occur in unacclimatized individuals at altitudes above 2,500 meters. They essentially comprise three clinical pictures: Acute Mountain Sickness (AMS), High Altitude Cerebral Edema (HACE), and High Altitude Pulmonary Edema (HAPE), which can manifest alone or in combination. All are triggered by hypobaric hypoxia, with individual predisposition, pre-existing medical comorbidities and in particular ascent rate and destination altitude influencing risk. AMS is the most common, presenting with headache, nausea, dizziness, and fatigue. Prevention includes slow ascent, pre-acclimatization, and eventually acetazolamide or dexamethasone. In severe cases, descent, oxygen therapy, and dexamethasone are key. HACE is considered a life-threatening complication of AMS with ataxia, altered consciousness, and neurological deficits. Pathophysiologically, vasogenic edema, hypoxic cell injury, and disturbed cerebrospinal fluid dynamics play a role. Treatment also includes descent, oxygen therapy, and dexamethasone. HAPE is a non-cardiogenic pulmonary edema due to an excessive hypoxic pulmonary vasoconstriction with consecutive elevation of pulmonary artery pressure and increased capillary pressure. Symptoms include dyspnea and cough; clinically, cyanosis and crackles are evident. Treatment requires descent, oxygen therapy, and possibly nifedipine or PDE-5-inhibitors. If untreated, HACE and HAPE progress rapidly and can be fatal. Prevention, early recognition and immediate treatment are crucial.","PeriodicalId":44874,"journal":{"name":"THERAPEUTISCHE UMSCHAU","volume":"82 6","pages":"209-214"},"PeriodicalIF":0.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146020186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Diving medicine in practice - in-depth knowledge is necessary]. 【潜水医学在实践中——深入的知识是必要的】。

IF 0.2

THERAPEUTISCHE UMSCHAU Pub Date : 2025-12-01 DOI: 10.23785/TU.2025.06.002

Martin Kraus, Christian Wölfel Wölfel

引用次数: 0

[Integrative oncology in everyday clinical practice: Continuing education and training]. [日常临床实践中的综合肿瘤学：继续教育和培训]。

IF 0.2

THERAPEUTISCHE UMSCHAU Pub Date : 2025-11-01 DOI: 10.23785/TU.2025.05.004

Gisèle Montavon, Sara Kohler, Theresia Knittel, Claudia M Witt

{"title":"[Integrative oncology in everyday clinical practice: Continuing education and training].","authors":"Gisèle Montavon, Sara Kohler, Theresia Knittel, Claudia M Witt","doi":"10.23785/TU.2025.05.004","DOIUrl":"https://doi.org/10.23785/TU.2025.05.004","url":null,"abstract":"Introduction: Integrative oncology is gaining increasing importance in cancer care. Patients seek additional support that addresses not only physical, but also emotional and spiritual needs. At the same time, studies show positive effects of complementary therapy intervention on quality of life and symptom control. Nevertheless, healthcare professionals often remain uncertain in clinical practice regarding the safety, effectiveness, and communication of such therapies. This article provides an overview of continuing education and training opportunities in the field of integrative oncology in Switzerland, highlights existing gaps, and defines key competencies required for safe and evidence-informed application. Based on international recommendations, practice-relevant learning content, educational formats, and interprofessional teaching strategies are presented. A particular focus is placed on the development of multiprofessional, evidence-based, and practice-oriented educational programs that address various professional groups - from physicians and nurses to complementary therapists. The aim is to promote interprofessional collaboration through structured training and to ensure the safe and effective use of complementary therapies in the oncological setting.","PeriodicalId":44874,"journal":{"name":"THERAPEUTISCHE UMSCHAU","volume":"82 5","pages":"163-167"},"PeriodicalIF":0.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145543204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Integrative palliative and end-of-life care in oncology]. [肿瘤学的综合姑息治疗和临终关怀]。

IF 0.2

THERAPEUTISCHE UMSCHAU Pub Date : 2025-11-01 DOI: 10.23785/TU.2025.05.005

Sandra Pittl, Corrado Bertotto, Natalie Kalbermatten

引用次数: 0

[Common features and core disciplines of integrative oncology]. 【结合肿瘤学的共同特点及核心学科】。

IF 0.2

THERAPEUTISCHE UMSCHAU Pub Date : 2025-11-01 DOI: 10.23785/TU.2025.05.002

Natalie Kalbermatten, Chantal Berna, Natacha Bordry, Marie-Estelle Gaignard, Isabell Ge, Sara Kohler, Tilly Nothhelfer, Florian Strasser, Nurgül Usluoglu, Claudia M Witt, Ursula Wolf

{"title":"[Common features and core disciplines of integrative oncology].","authors":"Natalie Kalbermatten, Chantal Berna, Natacha Bordry, Marie-Estelle Gaignard, Isabell Ge, Sara Kohler, Tilly Nothhelfer, Florian Strasser, Nurgül Usluoglu, Claudia M Witt, Ursula Wolf","doi":"10.23785/TU.2025.05.002","DOIUrl":"10.23785/TU.2025.05.002","url":null,"abstract":"Introduction: In Switzerland, a wide range of integrative oncology (IO) treatments is offered by various medical disciplines. A certificate of competence (SIWF: Swiss Institute for Medical Education, allows to bill from basic incurance) can be obtained for five disciplines: anthroposophic medicine (VAOAS), classical homeopathy (SVHA), phytotherapy (SMGP), TCM/acupuncture (ASA), and clinical hypnosis (SMSH). For Mind Body Medicine a CAS can be obtained (SFMBM). Integrative Nursing is an important therapeutic partner in many medical disciplines, with own established education programmes. These seven core disciplines of IO are based on different concepts and traditions, but they also have, at least in part, commonalities such as a multidimensional view of humanity, a focus on salutogenesis, the strengthening of self-efficacy, and the importance of lifestyle factors and individualised therapy. These core disciplines are offered with varying availability at the centres of the Swiss Network for Integrative Oncology (SNIO: www.integrative-oncology.ch), generally accompanying conventional oncological therapies and close, transparent communication with oncology specialists. The SNIO aims to develop quality criteria, coordinating treatment offers, promote network research, and encourage further training in order to enable coordinated and quality-assured care.","PeriodicalId":44874,"journal":{"name":"THERAPEUTISCHE UMSCHAU","volume":"82 5","pages":"144-156"},"PeriodicalIF":0.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145543188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Einführung: Integrative Onkologie. 综合肿瘤学导论。

IF 0.2

THERAPEUTISCHE UMSCHAU Pub Date : 2025-11-01 DOI: 10.23785/TU.2025.05.001

Florian Strasser, Marc Schläppi

引用次数: 0

[The role of integrative oncology in (post-curative) survivorship care]. [综合肿瘤学在（治疗后）生存护理中的作用]。

IF 0.2

THERAPEUTISCHE UMSCHAU Pub Date : 2025-11-01 DOI: 10.23785/TU.2025.05.006

Julia Reusch, Matthias Kröz, Tilly Nothhelfer, Florian Strasser

{"title":"[The role of integrative oncology in (post-curative) survivorship care].","authors":"Julia Reusch, Matthias Kröz, Tilly Nothhelfer, Florian Strasser","doi":"10.23785/TU.2025.05.006","DOIUrl":"https://doi.org/10.23785/TU.2025.05.006","url":null,"abstract":"Introduction: The number of cancer survivors - people who have overcome cancer or are living with the disease - is steadily increasing thanks to improved diagnostics and treatment. Studies indicate that many cancer survivors show good functional and quality of life scores in the long term, but comparisons with reference data show that cancer survivors still experience significant physical, psychological, and social impairments compared to the general population, even years after treatment. Cancer survivorship care focuses on developing care services for this issue, which has not been sufficiently addressed to date. Integrative oncology can offer a substantial contribution in the improvement the situation, particularly in light of the combination of evidence-based complementary therapies with conventional treatments, with the goal of enhancing well-being and quality of life, as well as active self-management (including nutrition and exercise in secondary prevention). Common problems experienced by cancer survivors, such as cancer-related fatigue, sleep disorders associated with cancer, and chemotherapy-induced polyneuropathy, can be reduced and the quality of life (QoL) of cancer survivors improved by integrating IO therapy concepts. Interventions from all core disciplines of IO can be used in many areas of survivorship care in a complementary, collaborative, and transparent manner alongside conventional medical treatments.","PeriodicalId":44874,"journal":{"name":"THERAPEUTISCHE UMSCHAU","volume":"82 5","pages":"173-178"},"PeriodicalIF":0.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145543214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Evidence, research methodology and quality criteria in integrative oncology: fundamentals, consensus and perspectives]. [综合肿瘤学的证据、研究方法和质量标准：基础、共识和观点]。

IF 0.2

THERAPEUTISCHE UMSCHAU Pub Date : 2025-11-01 DOI: 10.23785/TU.2025.05.003

Isabell Ge, Marie-Estelle Gaignard, Sara Kohler, Julia Reusch, Florian Strasser, Arnoud J Templeton

{"title":"[Evidence, research methodology and quality criteria in integrative oncology: fundamentals, consensus and perspectives].","authors":"Isabell Ge, Marie-Estelle Gaignard, Sara Kohler, Julia Reusch, Florian Strasser, Arnoud J Templeton","doi":"10.23785/TU.2025.05.003","DOIUrl":"10.23785/TU.2025.05.003","url":null,"abstract":"Introduction: Integrative oncology (IO) combines conventional cancer medicine with evidence-based complementary procedures, thereby placing special demands on the concept of evidence, research methodology, and the evaluation of care quality. This article highlights key theoretical, methodological, and practical principles. The classic concept of evidence is examined in detail through the three pillars of evidence-based medicine. Complementary research designs such as mixed methods, pragmatic studies, whole-systems approaches, and preference-based designs, are discussed as they offer new perspectives for generating valid and patient-centered evidence. In addition, regulation and practice-oriented quality criteria are presented as well as the current consensus process within the newly founded \"Swiss Network for Integrative Oncology\" (SNIO), which defines common standards, training structures, and research strategies. These efforts lay the foundation for the ongoing development of the field - toward an IO that is safe, effective, and truly patient-centered.","PeriodicalId":44874,"journal":{"name":"THERAPEUTISCHE UMSCHAU","volume":"82 5","pages":"157-162"},"PeriodicalIF":0.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145543167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Oral lichen planus - an overview of aetiology and treatment]. 口腔扁平苔藓——病因和治疗综述。

IF 0.2

THERAPEUTISCHE UMSCHAU Pub Date : 2025-09-01 DOI: 10.23785/TU.2025.04.007

Laurence Feldmeyer, Valérie G A Suter

引用次数: 0

[Escalation and de-escalation of therapy for high-risk melanomas]. [高危黑色素瘤的升级和降级治疗]。

IF 0.2

THERAPEUTISCHE UMSCHAU Pub Date : 2025-09-01 DOI: 10.23785/TU.2025.04.008

Reinhard Dummer, Lara Valeska Maul, Egle Ramelyte, Joanna Mangana

{"title":"[Escalation and de-escalation of therapy for high-risk melanomas].","authors":"Reinhard Dummer, Lara Valeska Maul, Egle Ramelyte, Joanna Mangana","doi":"10.23785/TU.2025.04.008","DOIUrl":"https://doi.org/10.23785/TU.2025.04.008","url":null,"abstract":"Introduction: For a long time, advanced melanoma was a difficult-to-treat disease with no effective survival strategies. With the development of checkpoint inhibitors and kinase inhibitors in the 21st century, treatment options have improved considerably. Recent studies indicate that adjuvant therapy with anti-PD1-antibodies significantly improves the recurrence-free survival in stage IIB/C patients without lymph node involvement. However, the challenge is to identify the right patients for long-term treatment, as many could be cured by surgery alone. Neoadjuvant therapy, in which systemic treatment is administered before the surgical removal of the macroscopic lymph node metastases, has proven to be promising. Neoadjuvant approaches, particularly with anti-PD1-antibodies, can significantly reduce the recurrence rate. Additionally, histological analysis of tumor tissue after neoadjuvant therapy could help identify patients who do not require further adjuvant treatment, thereby reducing side effects and costs. However, the implementation of neoadjuvant therapy in clinical practice faces challenges, such as the lack of approval in Switzerland and the need for specialized histopathological assessments. Future research efforts should focus on developing criteria for patient selection and validating the role of histopathological examinations in prognosis. A de-escalation of therapeutic approaches could lead to more patient-centered, resource-efficient medicine.","PeriodicalId":44874,"journal":{"name":"THERAPEUTISCHE UMSCHAU","volume":"82 4","pages":"135-137"},"PeriodicalIF":0.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0