{"title":"Usefulness of post-systolic index in facilitating stratification of risk in patients with intermediate- or low-risk non-ST-segment elevation acute coronary syndrome.","authors":"Kenji Masada, Takayuki Hidaka, Yoji Urabe, Naoya Mitsuba, Hironori Ueda","doi":"10.1007/s12574-023-00612-0","DOIUrl":"10.1007/s12574-023-00612-0","url":null,"abstract":"<p><strong>Background: </strong>Although there is reportedly a usefulness of left ventricular global longitudinal strain (LV GLS) on 2D speckle-tracking echocardiography in excluding significant coronary artery disease (CAD) in suspected intermediate- or low-risk non-ST-segment elevation-acute coronary syndrome (NSTE-ACS), the efficacy of post-systolic index (PSI) in this context is yet unknown. Therefore, we explored the usefulness of PSI in facilitating stratification of risk in patients with intermediate- or low-risk NSTE-ACS.</p><p><strong>Methods and results: </strong>We assessed 50 consecutive patients suspected of intermediate- or low-risk NSTE-ACS, and finally analyzed 43 patients whose echocardiographic images were suitable for strain analysis. All patients underwent CAG. Among the 43 analyzed patients, 26 had CAD, and 21 underwent percutaneous coronary intervention (PCI). Patients with CAD had higher PSI (25% [20.8-40.3%] vs 15% [8.0-27.5%], P = 0.007). Receiver-operator characteristic curve analysis identified that a PSI of > 20% detected performance of PCI (sensitivity 80.7%, specificity 70.6%, area under curve [AUC] 0.72, 95% confidence interval [CI] 0.57-0.88). Moreover, the AUC obtained using the GRACE risk score was 0.57 (95% CI 0.39-0.75), and increased to 0.75 (95% CI 0.60-0.90) when PSI and LV GLS were added. Thus, the addition of PSI and LV GLS improved the classification of performance of PCI (net reclassification improvement [95%CI] 0.09 [0.0024-0.18], P = 0.04).</p><p><strong>Conclusions: </strong>Post-systolic index is a useful parameter that can facilitate stratification of risk in patients with intermediate- or low-risk NSTE-ACS. We recommend measuring PSI in routine clinical practice.</p>","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":" ","pages":"157-164"},"PeriodicalIF":1.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10148042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rapid progression of mitral stenosis during watchful waiting for the asymptomatic degenerative severe aortic stenosis: a case of caseous calcification of mitral annulus.","authors":"Daiki Tsujimoto, Naoki Sumi, Satoshi Kobara, Yoshiaki Inoue, Yoshinobu Nakamura, Kinya Shirota","doi":"10.1007/s12574-022-00585-6","DOIUrl":"10.1007/s12574-022-00585-6","url":null,"abstract":"","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":" ","pages":"175-176"},"PeriodicalIF":1.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40681226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of echocardiography in patients treated with immune checkpoints inhibitors.","authors":"Kazuaki Tanabe, Junya Tanabe","doi":"10.1007/s12574-023-00621-z","DOIUrl":"10.1007/s12574-023-00621-z","url":null,"abstract":"<p><p>Immune-related adverse events occurring in the heart (cardiac immune-related adverse events; irAEs) by immune checkpoint inhibitors (ICIs) include myocarditis, arrhythmia, conduction disturbance, pericardial diseases, and takotsubo cardiomyopathy. Cardiac irAEs are rare but life-threatening. In cardio-oncology, the study of cardiac disorders caused by cancer treatment has recently attracted attention, and such studies may elucidate the pathophysiology of cardiac irAEs and contribute to management strategies. This review discusses the pathogenic mechanisms underlying cardiac irAEs and the role of echocardiography in patients treated with ICIs.</p>","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":" ","pages":"145-148"},"PeriodicalIF":1.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10115245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Significant dependency of left atrial strain on left ventricular longitudinal motion.","authors":"Tomoko Nishikage, Hiroyoshi Yamamoto, Naoe Fukumoto, Kayo Takahashi, Yukie Ota, Hanae Kusaki, Rina Aoyagi, Shintaro Beppu","doi":"10.1007/s12574-023-00605-z","DOIUrl":"10.1007/s12574-023-00605-z","url":null,"abstract":"<p><strong>Background: </strong>The effects of left ventricular longitudinal function on the left atrial strain, including the left atrial reservoir function, have not been adequately quantified.</p><p><strong>Methods: </strong>A total of 124 patients who underwent echocardiography were enrolled in this study. Left atrial strain analysis was performed using two-dimensional speckle tracking echocardiography, and the left atrial volume was derived using the modified Simpson's method. The peak left atrial strain (LAS) and left atrial expansion index (LAEI), as indices of left atrial reservoir function, were measured. The global longitudinal strain (GLS) and mitral annular plane systolic excursion (MAPSE), which are indices of contractile motion toward the left ventricular apex, were also measured. The correlation between LAS and candidate determinants, including left ventricular systolic longitudinal function, was evaluated, and multivariate regression analysis was performed.</p><p><strong>Results: </strong>A significant correlation was found between LAS and left ventricular systolic longitudinal functions, GLS (r = 0.63, p < 0.001), and MAPSE (r = 0.65, p < 0.001). Two models, which were selected by multiple regression analyses for LAS, included GLS or MAPSE as independent determinants. GLS and MAPSE were also the strongest predictors, among other factors.</p><p><strong>Conclusion: </strong>LAS, when determined by evaluating the left atrial reservoir function, was significantly associated with left ventricular function, especially the systolic longitudinal function. Left ventricular function should be considered when assessing left atrial function by LAS.</p>","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":" ","pages":"149-156"},"PeriodicalIF":1.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9557737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Practical approach of transthoracic echocardiography for pericardial cyst: a case report.","authors":"Kazuhiro Nomura, Takahisa Moronuki, Shinichi Takeuchi, Takuya Maeda, Shinichiro Iida, Keiji Yamamoto","doi":"10.1007/s12574-022-00574-9","DOIUrl":"https://doi.org/10.1007/s12574-022-00574-9","url":null,"abstract":"","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":"21 3","pages":"134-135"},"PeriodicalIF":1.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10016241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coronary cusp thrombosis: a rare cause of myocardial infarction.","authors":"Ramanathan Velayutham, Chinmay Parale, Ritesh Kumar, Avinash Anantharaj","doi":"10.1007/s12574-022-00573-w","DOIUrl":"https://doi.org/10.1007/s12574-022-00573-w","url":null,"abstract":"","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":"21 3","pages":"131-133"},"PeriodicalIF":1.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10072548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stuck valve and left atrial thrombus in a patient with hypereosinophilic syndrome.","authors":"Asahi Oshima, Yu Horiuchi, Taiki Ishizawa, Jiro Aoki, Tsuyoshi Taketani, Akitake Suzuki, Kengo Tanabe","doi":"10.1007/s12574-022-00581-w","DOIUrl":"https://doi.org/10.1007/s12574-022-00581-w","url":null,"abstract":"","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":"21 3","pages":"140-141"},"PeriodicalIF":1.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10390821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mersedeh Karvandi, Arash Mohammadi Tofigh, Saeed Ranjbar, Luigi P Badano
{"title":"Changes in blood flow vortices inside the left ventricle in COVID-19 patients with intraventricular clot despite a normal coronary and myocardial motion.","authors":"Mersedeh Karvandi, Arash Mohammadi Tofigh, Saeed Ranjbar, Luigi P Badano","doi":"10.1007/s12574-023-00603-1","DOIUrl":"https://doi.org/10.1007/s12574-023-00603-1","url":null,"abstract":"<p><strong>Purpose: </strong>Our clinical observations showed clot formations in different regions of the left ventricle of the heart in some COVID-19 patients with normal myocardial motion and coronary artery. The aim of this study was to examine the changes caused by COVID-19 disease on blood flow inside the heart as a possible etiology of intracardiac clot formation.</p><p><strong>Methods: </strong>In a synergic convergence of mathematics, computer science, and cardio-vascular medicine, we evaluated patients hospitalized due to COVID-19 without cardiac symptoms who underwent two-dimensional echocardiography. Patients with normal myocardial motions on echocardiography, normal coronary findings on noninvasive cardio-vascular diagnostic tests, and normal cardiac biochemical examinations but who presented with a clot in their left ventricle were included. To display the velocity vectors of the blood in the left ventricle, motion and deformation echocardiographic data were imported into MATLAB software.</p><p><strong>Results: </strong>Analysis and output of the MATLAB program indicted anomalous blood flow vortices inside the left ventricular cavity, indicating irregular flow and turbulence of the blood inside the left ventricle in COVID-19 patients.</p><p><strong>Conclusion: </strong>Our results suggest that in some COVID-19 patients, cardiac wall motion is not satisfactorily able to circulate the blood fluid in normal directions and that, despite normal myocardium, changes in the directions of blood flow inside the left ventricle might lead to clots in different zones. This phenomenon may be related to changes in blood properties, such as viscosity.</p>","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":"21 3","pages":"122-130"},"PeriodicalIF":1.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10017806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Echocardiographic reporting, artificial intelligence and natural language processing: correspondence.","authors":"Amnuay Kleebayoon, Viroj Wiwanitkit","doi":"10.1007/s12574-023-00614-y","DOIUrl":"https://doi.org/10.1007/s12574-023-00614-y","url":null,"abstract":"","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":"21 3","pages":"142-143"},"PeriodicalIF":1.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10037938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}