{"title":"Evaluation of right ventricular function using a novel three-dimensional speckle-tracking echocardiography automatic analysis system.","authors":"Konomi Sakata, Tomonori Kishino, Yoriko Sei, Shohei Shibasaki, Keiichiro Harashima","doi":"10.1007/s12574-025-00707-w","DOIUrl":"https://doi.org/10.1007/s12574-025-00707-w","url":null,"abstract":"<p><strong>Background: </strong>Right ventricular (RV) dysfunction is an important prognostic predictor of various cardiovascular diseases. However, the complex structural morphology of the RV limits the accurate quantitative assessment of its function. We investigated the utility of a novel three-dimensional speckle-tracking echocardiography (3D-STE) analysis system with automatic tracing and analysis functions to evaluate global and regional RV function.</p><p><strong>Methods: </strong>This study involved 60 healthy participants; 3D-STE analysis of the RV using 3D RV-STE automatic analysis software was compared with conventional two-dimensional echocardiography findings. We measured the peak global and regional 3D RV area change ratios (3D RV-ACRs). The peak regional 3D RV-ACRs were measured for three inlet, two apical, and two outflow tract segments of the RV; 3D RV ejection fraction (3D-RVEF) was also measured.</p><p><strong>Results: </strong>The 3D RV tracking automatically traced the RV endocardium and analyzed the RV function of the participants. The median global 3D RV-ACR was - 31.6% [interquartile range (IQR): - 33.4 to - 30.0%] and demonstrated a significant correlation with 3D-RVEF (r = 0.8957, p < 0.0001). The median values for the 3D RV inlet, RV outflow tract, and apical ACRs were - 36.3% (IQR: - 38.7 to - 34.6%), - 28.5% (IQR: - 32.5 to - 25.8%), and - 23.8% (IQR: - 27.1 to - 20.1%), respectively. Their contributions to the 3D-RVEF were 35.0%, 32.3%, and 4.2%, and to the global 3D RV-ACR were 44.5%, 39.6%, and 11.1%, respectively.</p><p><strong>Conclusions: </strong>The 3D RV-ACRs determined by the novel RV-specialized automatic 3D-STE analysis enable precise and quantitative assessment of RV function.</p>","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145213995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Indication and timing in tricuspid interventions.","authors":"Atsushi Sugiura, Georg Nickenig","doi":"10.1007/s12574-025-00705-y","DOIUrl":"https://doi.org/10.1007/s12574-025-00705-y","url":null,"abstract":"<p><p>Tricuspid regurgitation (TR), previously considered a secondary valvular disorder with limited clinical implications, is now recognized as a progressive and prognostically significant disease. The increasing prevalence due to aging populations and common comorbidities, such as atrial fibrillation and heart failure, has underscored the clinical urgency of addressing TR effectively. Transcatheter tricuspid valve interventions (TTVI) have emerged as valuable therapeutic alternatives, especially for patients at high surgical risk. This review addresses critical clinical questions regarding optimal intervention timing, patient selection, and treatment strategies, focusing particularly on disease progression, right-ventricular (RV) function, and recent clinical evidence. It emphasizes the importance of early identification and monitoring through echocardiographic and laboratory parameters, comprehensive risk stratification including pulmonary hypertension assessment, and the practical use of predictive tools such as TRISCORE. We summarize current guidelines for surgical versus transcatheter interventions and discuss advancements and limitations of transcatheter therapies, particularly transcatheter edge-to-edge repair (TEER) and transcatheter tricuspid valve replacement (TTVR). Ultimately, individualized decision-making based on anatomical considerations, RV function, and comorbidity burden is vital to maximizing therapeutic outcomes.</p>","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Expanding the role of strain echocardiography from diagnosis to prognosis in NSTEMI patients.","authors":"Macit Kalçık","doi":"10.1007/s12574-025-00708-9","DOIUrl":"https://doi.org/10.1007/s12574-025-00708-9","url":null,"abstract":"","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyungseop Kim, Jin-Gon Bae, Hee-Jeong Lee, Seonhwa Lee, In-Cheol Kim
{"title":"The implication of pericardial effusion in the third trimester for preeclampsia and heart failure in high-risk pregnant women.","authors":"Hyungseop Kim, Jin-Gon Bae, Hee-Jeong Lee, Seonhwa Lee, In-Cheol Kim","doi":"10.1007/s12574-024-00679-3","DOIUrl":"10.1007/s12574-024-00679-3","url":null,"abstract":"<p><strong>Background: </strong>With the growing number of high-risk pregnant women, echocardiography frequently reveals pericardial effusion (PE). However, the clinical implications of PE are unknown.</p><p><strong>Method: </strong>We analyzed a cohort of 406 high-risk pregnant women who underwent echocardiography in the third trimester between November 2019 and December 2022. The association between PE and clinical outcomes was assessed: the primary endpoint was the occurrence of preeclampsia, and the secondary composite outcomes were defined as the occurrence of preeclampsia, heart failure (HF), and pleural effusion within three months after birth.</p><p><strong>Results: </strong>Of the 406 high-risk pregnant women, 99 (24.4%) had PE. Women with PE were more likely to be younger, have higher blood pressure and soluble suppression of tumorigenicity-2, and develop gestational diabetes mellitus. They had increased left atrial and ventricular volumes, a higher mitral inflow, a lower systolic tissue velocity of the septal mitral annulus, a higher E/e' ratio and pulmonary artery systolic pressure, and a higher frequency of ≥ mild to moderate mitral/tricuspid regurgitation. PE was mainly associated with gestational hypertension. During follow-up, preeclampsia, HF, isolated pleural effusion, and any composite outcome were significantly more prevalent in women with PE. In multivariate analysis, PE was the most significant factor for adverse composite outcomes.</p><p><strong>Conclusion: </strong>In high-risk pregnant women, PE during the third trimester may be a novel biomarker for preeclampsia and peripartum HF. The timely implementation of echocardiographic surveillance during the third trimester in high-risk pregnant women may be helpful for the earlier recognition of PE, preeclampsia, and HF.</p>","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":" ","pages":"180-187"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical utility of the left atrial strain analysis.","authors":"Katsuji Inoue, Masaru Obokata","doi":"10.1007/s12574-025-00695-x","DOIUrl":"10.1007/s12574-025-00695-x","url":null,"abstract":"<p><p>The importance of left atrial (LA) function is recognized, especially when left ventricular function fails or atrial fibrillation occurs and heart failure (HF) develops. A compensatory mechanism of LA function unremittingly operates to maintain cardiac performance and prevent the occurrence of HF. LA function consists of three components: booster pump, reservoir, and conduit function. Echocardiography enables assessment of these components of LA function by LA volumetric changes in one cardiac cycle. Currently, LA strain has emerged as a valuable diagnostic and prognostic tool in patients with various cardiovascular diseases. An aging society is confronted with an issue of public health due to an increased number of patients with heart failure with preserved ejection fraction (HFpEF). Because effective medical and interventional approaches for patients with HFpEF are limited, early diagnosis and prevention are important to avoid a transition from preclinical HF stage to clinically overt HFpEF. Echocardiography with LA strain analysis and exercise stress echocardiography have the potential to identify patients with undiagnosed HFpEF, thus facilitating several preventive and therapeutic interventions. In this review, the development, measurement, and clinical application of LA strain are summarized and future perspectives in preventive medicine, accurate diagnosis, and therapeutic guidance for patients with HF are discussed.</p>","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":" ","pages":"145-155"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12378494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"\"Eclipsed mitral regurgitation\" incidentally detected during routine echocardiographic examination: a case of a 70-year-old woman.","authors":"Takakazu Kinugawa, Hiroki Matsuzoe, Nobuko Iwata, Hiroshi Takaishi","doi":"10.1007/s12574-024-00669-5","DOIUrl":"10.1007/s12574-024-00669-5","url":null,"abstract":"","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":" ","pages":"212-214"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determining pulmonary artery diameter on CT scans as basis for performing transthoracic echocardiography to screen for pulmonary hypertension in patients with pulmonary artery enlargement.","authors":"Kotaro Ouchi, Toru Sakuma, Ryo Akao, Ayumi Nojiri, Makoto Kawai, Hiroya Ojiri","doi":"10.1007/s12574-024-00674-8","DOIUrl":"10.1007/s12574-024-00674-8","url":null,"abstract":"<p><strong>Background: </strong>The current guidelines recommend patient stratification based on transthoracic echocardiography (TTE) to identify individuals with potential pulmonary hypertension (PH). We validated the relationship between PH and the pulmonary artery diameter (PAD) on computed tomography (CT) with peak tricuspid regurgitant velocity (TRV) measured by TTE for referral of patients with suspected PH for TTE screening.</p><p><strong>Methods: </strong>We performed a retrospective analysis of CT-based PAD of 2356 patients who underwent TTE from February 2, 2013 to December 25, 2019 at our institution. The thresholds for suspected PH based on TRV were determined using receiver operating characteristic curves based on PAD. Pearson's rank correlation coefficient was used to assess the relationship between PAD and TRV.</p><p><strong>Results: </strong>The area under the curve (AUC) of the PAD for suspected PH was statistically greater or comparable to others. The sex-specific PAD threshold for high PH probability were 29.4 mm (male: AUC, 0.86; sensitivity, 84.9%; specificity, 72.3%) and 27.8 mm (female: AUC, 0.83; sensitivity, 78%; specificity, 75.6%). Pearson's rank correlation coefficient showed a correlation between the PAD and TRV (male: ρ = 0.40, P < 0.001, female: ρ = 0.43, P < 0.001).</p><p><strong>Conclusions: </strong>The main PAD on CT findings served as a suitable marker for referral of patients with suspected PH for TTE screening. Patients exceeding the CT-derived PAD threshold, even incidentally, should undergo additional TTE for a comprehensive PH assessment.</p>","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":" ","pages":"165-173"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The usefulness of color Doppler images using epicardial echocardiography for diagnosis of coronary artery ostial stenosis in an infant.","authors":"Satoshi Koyama, Tsutomu Shinohara, Jun Sato, Kimihiro Yoshii, Shuichiro Yoshida, Takahisa Sakurai, Hiroshi Nishikawa","doi":"10.1007/s12574-024-00680-w","DOIUrl":"10.1007/s12574-024-00680-w","url":null,"abstract":"","PeriodicalId":44837,"journal":{"name":"Journal of Echocardiography","volume":" ","pages":"222-223"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}