Nepalese Journal of Ophthalmology最新文献_第2页

Ocular Findings among the Patients of Renal Transplantation 肾移植患者的眼部检查结果

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Nepalese Journal of Ophthalmology Pub Date : 2023-12-31 DOI: 10.3126/nepjoph.v15i1.52446

Madhu Thapa, G. B. Shrestha, Pragati Gautam, M. Sigdel

{"title":"Ocular Findings among the Patients of Renal Transplantation","authors":"Madhu Thapa, G. B. Shrestha, Pragati Gautam, M. Sigdel","doi":"10.3126/nepjoph.v15i1.52446","DOIUrl":"https://doi.org/10.3126/nepjoph.v15i1.52446","url":null,"abstract":"Introduction: Renal diseases are on rise globally due to increased incidence of non-communicable diseases as well as primary-kidney diseases and frequent use of nephrotoxic drugs. Only definite treatment of End-Stage-RenalDisease (ESRD) is renal transplantation. Immuno-suppressive-drugs are prescribed lifelong after renal transplantation especially steroids which can lead to various sight-threatening complications. Methods: This cross sectional, observational study included 62 eyes of 31 patients who had undergone renal transplantation, at least 3 months prior were referred from Nephrology Department. Comprehensive eye evaluation was done at B. P. Koirala Lions Centre for Ophthalmic Studies (BPKLCOS), Department of Ophthalmology, Institute of Medicine. Results: The average age of participants was 37 ±10.57 years with 77.4 % (n=24) male. Mean duration of renal transplant was 5.10 ± 3.61 years. Fifty-eight percent (n=18) had hypertensive kidney disease. Diabetes Kidney disease, recurrent UTI, CKD of unknown causes and combined case of diabetes plus hypertension were seen in 6.4% (n=2) each. Sixty percent of the patients had some kind of ocular involvement. Twenty-nine percent (n=18) had subnormal visual acuity of ≤ 6/9. Cataract was seen in 29% (n=18) of eyes followed by pinguecula (17.7%, n=11) and hypertensive-retinopathy (17.7%, n=11). Glaucoma and Diabetic-retinopathy were seen only in 6.4% (n= 4) of each eyes. There was no association seen between ocular findings with cause of renal transplant, duration of transplant and renal function status in bivariate analysis. Conclusions: Some form of ocular abnormality is commonly seen in patients of renal transplantation who are on immunosuppressive drugs. However, incidence of sight threatening complications are rare.","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139130239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Indication and Outcome of Paediatric Keratoplasty at a Tertiary Referral Eye Hospital in Nepal 尼泊尔一家三级眼科转诊医院的儿科角膜移植手术的适应症和结果

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Nepalese Journal of Ophthalmology Pub Date : 2023-12-31 DOI: 10.3126/nepjoph.v15i1.50357

R. Rana, L. Bajracharya, Reeta Gurung, Radhika Upreti, Manish Poudel, Pradeep Banjara, S. Thapa

{"title":"Indication and Outcome of Paediatric Keratoplasty at a Tertiary Referral Eye Hospital in Nepal","authors":"R. Rana, L. Bajracharya, Reeta Gurung, Radhika Upreti, Manish Poudel, Pradeep Banjara, S. Thapa","doi":"10.3126/nepjoph.v15i1.50357","DOIUrl":"https://doi.org/10.3126/nepjoph.v15i1.50357","url":null,"abstract":"Introduction: Paediatric keratoplasty is rarely performed surgery with high risk of graft failure. Developing countries have not benefited due to lack of sufficient facilities and trained surgeons. Objectives: The objectives of the study were to analyze the indications and its outcome in terms of vision and graft survival. Materials and methods: This retrospective chart review used electronic medical records from January 2017 to December 2019 of all consecutive patients aged upto18 years or below that underwent paediatric keratoplasty after ethical approval at Tilganga Institute of Ophthalmology. Outcome was defined as anatomical or visual success and graft clarity. Different demographic and surgical parameters were studied among 59 eyes of 48 patients. Results: Mean age of recipient was 12.23± 3.81 years. Majority 37 (52.5%) had unilateral grafts with keratoconus being the most common 24 (40.6%) acquired non-traumatic indication. Mean post-operative best corrected visual acuity 0.6 Logmar was significantly (p <0.001) low as compared to preoperative 1.3 Logmar. Overall graft survival rate was 47 (78%) at one-year follow-up; keratoconus accounting for 24 (100%). Major factors in contributing for graft failure were rejection, infection, and glaucoma. Conclusion: A good outcome in terms of anatomical and visual success was achieved in our study. Keratoconus has an excellent graft survival. Visual rehabilitation by cycloplegic refraction should be done to prevent amblyopia. Enhancing the training of surgeons and addressing challenges faced in a paediatric population will help decrease corneal blindness among paediatric patients in the future.","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139133107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Developing Artificial Intelligence Model for Prediction of Diabetic Retinopathy and Delivering in a real-world Local Context: BP Eye Foundation’s Perspective 开发用于预测糖尿病视网膜病变的人工智能模型，并在现实世界的本地环境中实施：BP 眼科基金会的视角

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Nepalese Journal of Ophthalmology Pub Date : 2023-12-31 DOI: 10.3126/nepjoph.v15i1.59413

Arjun Shrestha, Pranita Upadhyaya, Madan P. Upadhyay

引用次数: 0

Retinal Nerve Fiber Layer and Macular Thickness in Patients with Type 2 Diabetes Mellitus without Retinopathy Using Optical Coherence Tomography: A Comparative Study 使用光学相干断层扫描测量无视网膜病变的 2 型糖尿病患者的视网膜神经纤维层和黄斑厚度：比较研究

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Nepalese Journal of Ophthalmology Pub Date : 2023-12-31 DOI: 10.3126/nepjoph.v15i1.47629

Samiksha Bhattarai, P. Lavaju, B. Badhu, Sangeeta Shah, Santosh Chaudhary, Robin Maskey, Ashesh Koirala

{"title":"Retinal Nerve Fiber Layer and Macular Thickness in Patients with Type 2 Diabetes Mellitus without Retinopathy Using Optical Coherence Tomography: A Comparative Study","authors":"Samiksha Bhattarai, P. Lavaju, B. Badhu, Sangeeta Shah, Santosh Chaudhary, Robin Maskey, Ashesh Koirala","doi":"10.3126/nepjoph.v15i1.47629","DOIUrl":"https://doi.org/10.3126/nepjoph.v15i1.47629","url":null,"abstract":"Introduction: Diabetes leads to an alteration in retinal nerve fiber layer (RNFL) thickness and macular thickness which can easily be detected with optical coherence tomography (OCT). Objectives: This study was done to compare the RNFL and macular thickness between diabetic patients without retinopathy and non-diabetic patients so that it would be useful in the early detection of retinal changes if present. The correlation between the RNFL and macular thickness with metabolic blood parameters of diabetic subjects was also studied. Materials and methods: This is an observational, cross-sectional, hospital-based study including 120 subjects who were further divided into two groups. Group A consisted of 60 diabetic patients without retinopathy and group B consisted of 60 non-diabetic patients. The blood parameters were recorded and the RNFL thickness and macular thickness were compared between the two groups after evaluation by OCT. Results: The average central macular thickness was found to be more in group A but was statistically insignificant (p=0.29). Macular thickness in the superior quadrant was significantly higher among group A when compared with group B (p=0.01). Whereas RNFL thickness difference between the two groups was statistically insignificant (p=0.53). Blood urea showed significant positive correlation (r=0.269) with central macular thickness (p=0.03). Conclusion: Our study showed that diabetic patients without retinopathy could have increased macular thickness in the superior quadrant when compared with normal people whereas RNFL thickness may not alter. The blood urea levels of the diabetic patients can provide us clues regarding possible retinal changes.","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139136447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical Outcomes of Ahmed Glaucoma Valve and Aurolab Aqueous Drainage Implant in Nepalese Eyes: Comparison in the First Year 在尼泊尔人眼中使用 Ahmed 青光眼瓣膜和 Aurolab 眼液引流植入物的手术效果：第一年的比较

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Nepalese Journal of Ophthalmology Pub Date : 2023-12-31 DOI: 10.3126/nepjoph.v15i1.52436

Anil Parajuli, I. Paudyal, P. Joshi, S. Thapa

{"title":"Surgical Outcomes of Ahmed Glaucoma Valve and Aurolab Aqueous Drainage Implant in Nepalese Eyes: Comparison in the First Year","authors":"Anil Parajuli, I. Paudyal, P. Joshi, S. Thapa","doi":"10.3126/nepjoph.v15i1.52436","DOIUrl":"https://doi.org/10.3126/nepjoph.v15i1.52436","url":null,"abstract":"Introduction: Glaucoma is the leading cause of irreversible blindness worldwide. Though trabeculectomy still remains the surgical modality of choice for the management of glaucoma, the outcome of glaucoma drainage devices (GDDs) too has been encouraging in recent years. Objectives: To compare the surgical outcomes of Ahmed glaucoma valve (AGV) and Aurolab aqueous drainage implant (AADI) in cases of refractory glaucoma in Nepalese eyes. Materials and methods: We retrospectively studied the charts of the patients with refractory glaucoma who had undergone GDD implantation at Tilganga Institute of Ophthalmology (TIO), Kathmandu, Nepal. Depending on which GDD was implanted, the eyes of the patients were divided into: AGV group and AADI group. The outcome measures of the study were intraocular pressure (IOP), requirement of antiglaucoma medications (AGMs), surgical success and complications. Results: There were 24 eyes of 23 patients in AGV group and 31 eyes of 30 patients in AADI group with a median (quartiles) follow-up of 12 (12,12) months. In the final visit, IOP and AGMs were both significantly lower than the baseline in both the groups (P <0.001). The median IOP in mmHg and AGMs were both significantly lower in the AADI group compared to AGV group in the final visit, p <0.001 and p=0.002, respectively. The overall success was similar in both the groups: AGV (n=22, 91.67%) and AADI (n=29, 93.55%), p=1.0. However, complete success was significantly more in AADI group (n=16, 51.61%) compared to AGV group (n=6, 25%), p=0.046. Complications and their rates were comparable between the two groups (p=0.4). Conclusion: Both AGV and AADI safely and effectively reduced the IOP and the number of AGMs in cases of refractory glaucoma in Nepalese eyes.","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139136658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intravitreal Bevacizumab in Management of Persistent Secondary Macular Hole with Epiretinal Proliferation. 玻璃体内贝伐单抗治疗伴有视网膜外增殖的持续性继发性黄斑孔。

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Nepalese Journal of Ophthalmology Pub Date : 2023-07-01 DOI: 10.3126/nepjoph.v15i2.55033

Ugyen Zangmo, Sushma Jayanna, Mahesh P Shanmugam

引用次数: 0

Pterygium Surgery with Autologous Graft with Glue versus Sutures. 翼状胬肉手术中的自体移植与胶合与缝合

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Nepalese Journal of Ophthalmology Pub Date : 2023-07-01 DOI: 10.3126/nepjoph.v15i2.64638

Dikshya Bohara

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Surgeries and Outcomes in Subluxated and Dislocated Lens in Eastern Nepal. 尼泊尔东部晶状体半脱位和脱位的手术及结果。

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Nepalese Journal of Ophthalmology Pub Date : 2023-07-01 DOI: 10.3126/nepjoph.v15i2.56396

Pranav Shrestha, Sadhana Sharma, Rinkal Suwal, Purushottam Joshi, Prava Subedi

{"title":"Surgeries and Outcomes in Subluxated and Dislocated Lens in Eastern Nepal.","authors":"Pranav Shrestha, Sadhana Sharma, Rinkal Suwal, Purushottam Joshi, Prava Subedi","doi":"10.3126/nepjoph.v15i2.56396","DOIUrl":"https://doi.org/10.3126/nepjoph.v15i2.56396","url":null,"abstract":"Introduction: Many ocular or systemic conditions can cause weakening of the zonules, leading to subluxation or complete dislocation of lens into the anterior chamber or vitreous cavity.Objectives: To evaluate the outcome of surgery in cases with subluxated and dislocated lens.Materials and methods: Retrospective chart review of all cases with subluxated and dislocated lens who underwent surgery in a one-year period from 2019 January to 2019 December was conducted. Demographic profile, systemic comorbidities, initial and final best corrected visual acuity (BCVA), surgical procedure were recorded along with all the intraoperative and post-operative complications.Results: A total of 62 eyes of 60 patients with mean age of 50.18 ± 15.18 years (18 to 87 years) were included with the modal duration of presentation of one week. Among these, trauma was found to be the most common etiology. Subluxation was present in 55 eyes and seven eyes had dislocation. Intracapsular Cataract Extraction (ICCE) was performed in 41 while 21 underwent Extracapsular Cataract Extraction (ECCE); and surgical intervention elicited a statistically significant (p < 0.05) improvement in the visual acuity. The BCVA was statistically better among the pseudophakic patient. Most common complication encountered intraoperatively was vitreous loss and post operatively was significant corneal edema.Conclusion: Cataract extraction in cases with subluxated and dislocated lens due to different etiology results in the improvement in the visual acuity of the patient. In cases where ECCE cannot be performed, ICCE also results in comparable visual improvement.","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral Optic Neuritis in a Patient with Enteric Fever: A Case Report. 肠炎患者的双侧视神经炎：病例报告。

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Nepalese Journal of Ophthalmology Pub Date : 2023-07-01 DOI: 10.3126/nepjoph.v15i2.55281

Sundip Dware Chhetri, Keepa Vaidya, Suman Lamichhane, Sudeep Lal Rajbhandari, Shailendra Katwal

引用次数: 0

Comparability of Measurement of Astigmatism between URk-800F Auto Refracto-keratometer and MS-39 Anterior Segment Optical Coherence Tomography in Patients with Refractive Error. URk-800F 自动屈光角膜仪和 MS-39 光学相干断层扫描对屈光不正患者散光测量的可比性。

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Nepalese Journal of Ophthalmology Pub Date : 2023-07-01 DOI: 10.3126/nepjoph.v15i2.57044

Namrata Gupta, Samrina Maharjan, Suman Sapkota

{"title":"Comparability of Measurement of Astigmatism between URk-800F Auto Refracto-keratometer and MS-39 Anterior Segment Optical Coherence Tomography in Patients with Refractive Error.","authors":"Namrata Gupta, Samrina Maharjan, Suman Sapkota","doi":"10.3126/nepjoph.v15i2.57044","DOIUrl":"10.3126/nepjoph.v15i2.57044","url":null,"abstract":"Introduction: Accurate refractive error assessment is the first and the most important step of ocular examination. A reliable screening method of refractive status is important for early detection and prevention of blinding complications of uncorrected refractive error.Objectives: To evaluate the comparability of astigmatism measured by an auto-refractometer (URk-800F) with the measurements of the gold standard anterior segment optical coherence tomography (AS-OCT).Materials and methods: This cross-sectional observational study was conducted in a tertiary eye centre in Kathmandu from February 2023 to June 2023. A total of 100 patients with best corrected visual acuity of ≥ 20/20, spherical refractive error with cylindrical error of more than and equal to -0.75 and no pathology detected on slit lamp examination were taken by consecutive sampling method. Ethical approval was taken for the study. The data were entered into Microsoft Excel and analysed using Bland-Altman analysis.Results: The mean cylindrical power and axis was -2.33 D and 88 degrees for the right eye and -2.32 D and 122 degrees for the left eye respectively, as measured by MS-39 AS-OCT. For URK 800-F Auto-refracto Keratometer, the mean cylindrical power and axis was -2.31 D and 89 degrees for the right eye and -2.27 D and 124 degrees for the left eye.Conclusion: The findings of this study conclude that an auto-refractometer can be used as an effective tool for identification of spherical refractive error as well as measurement of accurate cylindrical power and cylindrical axis in low resource primary care settings.","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0