Nepalese Journal of Ophthalmology最新文献

{"title":"From Sandbags to Systems: Six Decades of Eye Care in Nepal and the Road Ahead.","authors":"Madan Prasad Upadhyay, Aashish Raj Pant, Purushottam Joshi","doi":"10.3126/nepjoph.v17i34.90888","DOIUrl":"https://doi.org/10.3126/nepjoph.v17i34.90888","url":null,"abstract":"","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":"17 34","pages":"1-4"},"PeriodicalIF":0.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Case of Sebaceous Gland Carcinoma Mimicking Recurrent Chalazion in a Young Patient.","authors":"Parul Mittal, Saroj Gupta, Manal M Khan, Priyanka","doi":"10.3126/nepjoph.v17i34.75520","DOIUrl":"10.3126/nepjoph.v17i34.75520","url":null,"abstract":"<p><strong>Introduction: </strong>Chalazion is a common eyelid lesion usually treated conservatively or with minor surgical interventions, such as incision and curettage or intralesional steroid injections. However, recurrent or atypical chalazion in a young adult patient warrants further investigation to exclude malignant conditions such as sebaceous gland carcinoma (SGC).</p><p><strong>Case: </strong>Here an unusual case of SGC presenting with a recurrent chalazion in a young adult patient is reported, which was diagnosed by a biopsy for histopathological examination.</p><p><strong>Observation: </strong>Histopathology revealed sebaceous gland carcinoma. The patient subsequently underwent wide local excision of the lesion, followed by oculoplastic reconstruction. Post-operative follow-up over one year revealed no recurrence or metastasis.</p><p><strong>Conclusion: </strong>This case highlights the importance of considering malignancies like sebaceous gland carcinoma in recurrent or atypical chalazion cases, even in young patients. Early biopsy and histopathological evaluation are essential for timely diagnosis and management to prevent metastasis and ensure better patient outcomes.</p>","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":"17 34","pages":"110-114"},"PeriodicalIF":0.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ocular Biometric Changes Following Scleral Buckle Surgery for Rhegmatogenous Retinal Detachment.","authors":"Shilpa Yellur Devegowda, Sowmya Shree Bangalore Venkatesh Murthy, Hemalatha Bangalore Chikkahanumanthappa, Kalpana Badami Nagaraja, Kavitha Lingaraju Tumbadi","doi":"10.3126/nepjoph.v17i34.77125","DOIUrl":"10.3126/nepjoph.v17i34.77125","url":null,"abstract":"<p><strong>Introduction: </strong>Rhegmatogenous retinal detachment (RRD) is separation of neurosensory retina and Retinal Pigment Epithelium, due to full-thickness retinal breaks. Scleral Buckling (SB) is extraocular procedure done to reattach retina by counteracting vitreoretinal traction and altering globe's geometry.</p><p><strong>Objective: </strong>To study various ocular changes and visual outcomes after buckling among patients of RRD.</p><p><strong>Methodology: </strong>A longitudinal observational study was conducted with prospective data collection in a tertiary health care centre from 2019 November to 2021 December after ethical clearance. It included 40 RRD patients who underwent scleral buckling (sizes 279, 276, and 281), recruited by consecutive sampling technique. Study excluded tractional detachment or pathologies affecting retinal visualisation. All patients were evaluated for visual acuity, refraction, intraocular pressure (IOP), axial length (AL) and anterior chamber depth (ACD) both preoperatively and post-operatively at one week, one month, and three months. Statistical analysis was done with Microsoft Excel Sheet using appropriate statistical tests.</p><p><strong>Result: </strong>Visual acuity showed significant (p-value <0.05) improvement at three months post-operatively. Mean AL increased from pre-operative 24.15 mm to 26.00 mm at one week, decreased to 25.55 mm at one month and further reduced to 25.02 mm at three months post-operatively. Mean ACD decreased from pre-operative 3.20 mm to 2.60 mm at one week, then 2.81 mm at one month and three months post-operatively. Mean IOP rose from pre-operative 12.10 mmHg to 16.45 mmHg at one week, 14.10 mmHg at one month and 13.95 mmHg at three months postoperatively. At three months, Compound myopic astigmatism was noted in 75% of patients on AR and 45% on manual refraction.</p><p><strong>Conclusion: </strong>The ocular biometric changes following buckling tend to gradually return to baseline, along with visual improvement. These findings support the safety and efficacy of the procedure; also emphasising the importance of continued post-operative monitoring to ensure optimal visual outcomes.</p>","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":"17 34","pages":"68-77"},"PeriodicalIF":0.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal Endothelial Morphology in Type II Diabetic versus Non-Diabetic Individuals using Specular Microscopy.","authors":"Suhana Shrestha, Poonam Shrestha, Chandra Maya Gurung","doi":"10.3126/nepjoph.v17i34.74598","DOIUrl":"https://doi.org/10.3126/nepjoph.v17i34.74598","url":null,"abstract":"<p><strong>Introduction: </strong>Diabetes is one of the major causes of comorbidities in elderly patients. Impaired vision and blindness in chronic diabetic population occurs due to poor corneal wound healing, corneal oedema, and other abnormalities of corneal layers as a result of accumulation of toxic products within cornea. Literature has shown corneal endothelial changes in diabetes in different populations but study on the Nepali population is sparse.</p><p><strong>Objective: </strong>To compare the corneal endothelial parameters between type II diabetics and non-diabetics.</p><p><strong>Methodology: </strong>A hospital-based, analytical, cross-sectional study was conducted after ethical approval from 2022 January to 2023 June using a CEM 530 NIDEK Spectral microscope to analyse the Endothelial Cell Density (ECD), Central Corneal Thickness (CCT), Hexagonality (HEX), and Coefficient of Variance (CoV). After meeting the selection criteria, 74 type II diabetic cases and 74 (age and sex-matched) controls were enrolled in this study using consecutive sampling method.</p><p><strong>Result: </strong>The ECD was relatively higher in OD of diabetics than controls (2756.3 ± 228 cells/mm2 vs. 2748.7 ± 279.4 cells/mm2). The CoV was significantly higher in diabetics (OD 32.5 ± 5.4; OS 32 ± 4.7 vs. OD: 30.9 ± 3.8, OS: 30.5 ± 3.4). The HEX was significantly decreased in diabetics (OD: 65.5 ± 4.1, OS: 65.4 ± 5 vs. OD: 67 ± 5.2, OS: 67.1 ± 4.6). The CCT was significantly increased in diabetics (OD: 531.6 ± 29.9μm, OS: 538.3 ± 28.9μm vs. OD: 519.2 ± 32.3μm, OS: 526.1 ± 31.2μm). The duration of diabetes showed no significant difference in corneal parameters. However, diabetics with HbA1c <6.5 had significantly increased CCT than those with HbA1c >6.5.</p><p><strong>Conclusion: </strong>There were significant changes in corneal endothelial morphology in patients with type II diabetes.</p>","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":"17 34","pages":"28-35"},"PeriodicalIF":0.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Hamartoma of Retina and Retinal Pigment Epithelium Masquerade as Choroidal Melanoma in Young Patient.","authors":"Anupama Amatya, Saksham Tamang, Purnima Rajkarnikar Sthapit","doi":"10.3126/nepjoph.v17i34.75958","DOIUrl":"https://doi.org/10.3126/nepjoph.v17i34.75958","url":null,"abstract":"<p><strong>Introduction: </strong>Combined hamartoma of retina and retinal pigment epithelium is a rare benign ocular tumour resulting from abnormal proliferation of glial cells, vascular tissue and pigment epithelial cells Case: A 29-year-old male presented with complaint of diminution of vision in his right eye, noticed incidentally during screening.</p><p><strong>Observation: </strong>On examination, a flat, unilateral, solitary, greyish brown peri-papillary lesion with irregularly pigmented border with an epiretinal membrane in right eye. The Optical Coherence Tomography showed a thickened retina with disorganisation of retinal layers, a hyper-reflective inner retinal layer with fine retinal traction peaks, and presence of an epiretinal membrane. Histopathological examination was not done.</p><p><strong>Conclusion: </strong>Combined hamartoma of retina and retinal pigment epithelium is a rare benign tumour. Proper diagnosis is important as it can be confused with more severe pathologies like choroidal melanoma, Retinal pigment epithelium adenocarcinoma.</p>","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":"17 34","pages":"105-109"},"PeriodicalIF":0.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Eye Donation Awareness of Next-of-Kin and Eye Donation after Grief Counselling.","authors":"Oshin Puri, Neeti Gupta, Sanjeev Kumar Mittal","doi":"10.3126/nepjoph.v17i34.74013","DOIUrl":"https://doi.org/10.3126/nepjoph.v17i34.74013","url":null,"abstract":"<p><strong>Introduction: </strong>Corneal transplantation is a definitive treatment for corneal blindness, but only 25% patients receive corneas due to donor scarcity. Community awareness initiatives increase willingness to donate, but little is known about how awareness influences actual donation.</p><p><strong>Objective: </strong>To assess the association between pre-existing eye donation awareness of the next-of-kin and donation after grief counselling.</p><p><strong>Methodology: </strong>The 164 most stable next-of-kin were enrolled in this analytical cross-sectional study with due consent and ethical approval. Participants were approached by the Eye Donation Counsellor (EDC). After assessing their awareness about eye donation through the Ronanki \"Awareness and Perception on Eye Donation\" questionnaire, the EDC grief counselled the next-of-kin.</p><p><strong>Result: </strong>Thirty-four (20.7%) brothers and 33 (20.1%) fathers of the deceased were the most stable next-of-kin. In total 139 (84.8%) participants were aware of eye donation. The mean awareness, knowledge, and perception scores of the study population were 2.46 ± 1.34 out of 4, 2.73 ± 2.37 out of 6, and 1.79 ± 1.72 out of 4, respectively. Eye care professionals (105, 64.02%) and mass media (61, 37.19%) were identified as the most common sources of information. While 86 (52.4%) expressed willingness to donate, only 12 (7.31%) donated, and there was one (0.61%) voluntary donation. Counselling and the belief that eye donation is a noble deed were identified as the major motivators. Chi-square (𝛘2) and p-value for the association between eye donation and the pre-existing awareness of the next-of-kin were 0.95 and 0.33, respectively, suggesting no significant association. However, awareness was associated with the increased willingness to donate eyes (𝛘2 = 19.35; p-value <0.001).</p><p><strong>Conclusion: </strong>There was no significant association between eye donation and awareness of the next-of-kin.</p>","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":"17 34","pages":"17-27"},"PeriodicalIF":0.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Spectrum and Visual Outcomes of Strabismus: A Hospital-based Study from Eastern Nepal.","authors":"Neha Priyadarshani Chaudhary, Prerna Aryal Kafle, Nancy Goyal, Sajjad Ahmed Khan","doi":"10.3126/nepjoph.v17i34.83032","DOIUrl":"https://doi.org/10.3126/nepjoph.v17i34.83032","url":null,"abstract":"<p><strong>Introduction: </strong>Strabismus, a condition marked by abnormal ocular alignment, is relatively common and can lead to amblyopia. Beyond visual impairment, it affects self-esteem, social interaction, and overall quality of life. Misconceptions and stigma may further exacerbate psychosocial challenges, making early evaluation and management essential.</p><p><strong>Objective: </strong>To assess the clinical profile, aetiology, and visual outcomes of patients with strabismus at Birat Medical College Teaching Hospital.</p><p><strong>Methodology: </strong>This analytical, cross-sectional, hospital-based study included all patients presenting with strabismus to the Ophthalmology Outpatient Department from 2024 July to 2025 June. Data on age of onset, duration, type of deviation, and associated factors were collected after ethical approval (prospectively). Convenience sampling method was utilised. Visual acuity was measured, followed by cycloplegic retinoscopy and anterior or posterior segment examinations. Ocular deviation was quantified using the Prism Bar Cover Test and Modified Krimsky Test, while binocular single vision and stereopsis were evaluated with the Worth Four Dot and Titmus Fly Tests. Ethical approval and informed consent were obtained beforehand. Data were analysed using Chi-square and t-tests.</p><p><strong>Result: </strong>A total of 102 patients were included: 57 (55.88%) males and 45 (44.12%) females. The most affected age group was 16-30 years (41, 40.20%). Esotropia was the predominant type (46, 45.10%), followed by exotropia (38, 37.30%). Congenital strabismus accounted in 59 (57.8%), and 34 (33.3%) had associated amblyopia. Stereopsis was preserved in 75 (73.3%) of patients. Esotropic patients had 0.49 times the odds of visual acuity worse than 6/18 compared to exotropes.</p><p><strong>Conclusion: </strong>Esotropia is the most common form of strabismus, with amblyopia present in one-third of cases. Early detection and intervention are critical for preserving vision and enhancing quality of life.</p>","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":"17 34","pages":"88-96"},"PeriodicalIF":0.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness, Knowledge, and Practice on Retinal Diseases at High-altitude of Nepal.","authors":"Raba Thapa, Sanduk Ruit, Manish Poudel, Pratibha Neupane, Pradeep Banjara, Sushma Duwal, Elena Gurung, Geoffrey Craig Tabin","doi":"10.3126/nepjoph.v17i34.68246","DOIUrl":"10.3126/nepjoph.v17i34.68246","url":null,"abstract":"<p><strong>Introduction: </strong>Retinal disorders are the major causes of visual impairment in Nepal. Limited access to eye care service in high altitude regions, along with low awareness and knowledge on the retinal diseases delays timely treatment and care.</p><p><strong>Objective: </strong>To assess the awareness, knowledge, and practices on major retinal disorders at high-altitude in Nepal.</p><p><strong>Methodology: </strong>An analytical cross-sectional study was carried out to assess the retinal disease prevalence at three high-altitude districts of Nepal namely Manang, Mustang, and Solukhumbu from 2023 May to 2023 July after ethical clearance. The sample size of 308 with the age 40 years and above were included with random sampling. Awareness, knowledge, and practice on major retinal disease on diabetic retinopathy (DR), age-related macular degeneration (AMD), hypertensive retinopathy (HR), and high-altitude retinopathy (HAR) were assessed. Facetoface interviews were conducted after obtaining informed written consent. Ethical approval was granted by the Nepal Health Research Council, and data were analysed using IBM SPSS v.20.</p><p><strong>Result: </strong>A total of 338 study participants were enrolled. The mean age was 56.98±11.13 years with female preponderance (216, 63.9%). Three-fifth (61.8%) were literate. Awareness was found among 131 (38.76%) on diabetes mellitus affecting eye, 19 (5.6%) on AMD, 118 (34.9%) on hypertension affecting eye, and 273 (80.8%) on high-altitude affecting eye. However, only five (1.5%) were aware that high-altitude could affect retina and none were aware of its preventive measures. Eleven (33.3%) of people with diabetes had regular eye exams. One respondent had AMD, however he did not receive frequent eye examinations. Only eight (8.3%) of those with hypertension had undergone regular eye check-ups.</p><p><strong>Conclusion: </strong>The awareness, knowledge, and practice on major retinal diseases including high-altitude retinopathy was low among the population of high-altitude in Nepal. Emphasis should be given on raising awareness activities besides enhancing the access to eye care services.</p>","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":"17 34","pages":"45-56"},"PeriodicalIF":0.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of Silicone Oil Removal After Pars Plana Vitrectomy at A Tertiary Eye Hospital, Nepal.","authors":"Ashma Manandhar, Eli Pradhan, Sanjita Sharma, Sushma Duwal, Raba Thapa","doi":"10.3126/nepjoph.v17i34.66179","DOIUrl":"10.3126/nepjoph.v17i34.66179","url":null,"abstract":"<p><strong>Introduction: </strong>Silicone oil is used in complicated retinal detachment since many decades. It is associated with many complications so, silicone oil removal is to be done once the retina is attached. Retinal re-detachment is the most serious complication after its removal.</p><p><strong>Objective: </strong>To evaluate the surgical outcomes and ocular complications after silicone oil removal in cases of rhegmatogenous retinal detachment.</p><p><strong>Methodology: </strong>It was a hospital-based observational study conducted after ethical clearance among the patients that underwent silicone oil removal between 2018 January to 2018 December at Tilganga Institute of Ophthalmology. Consecutive sampling technique was used for the study. Inclusion criteria were patients undergoing silicone oil removal for the first time with or without cataract surgery during the study duration. Exclusion criteria were cases with retinal detachment noted at the time of silicone oil removal, patient younger than 18 years, scleral thinning at the site of sclerotomy, use of silicone oil tamponade other than 1000 centistoke. Visual acuity, intraocular pressure, retinal re-detachment, corneal complications were evaluated in this study Result: Total 88 eyes of 88 patients (67.1% male) were included in this study. Mean age of the patient was 62 years with standard deviation of 3.4 years (range 37-75 years). Anatomically success was obtained in 75 (85.2%) cases. Best corrected visual acuity was improved in 43 (48.86%). Complications after oil removal were re-detachment of retina in 13 (14.8%), ocular hypotony two (2.27 %), ocular hypertension three (3.40%), corneal decompensation eight (9.09%).</p><p><strong>Conclusion: </strong>This study showed an overall improvement in post-operative visual acuity after silicone oil removal but anatomical success may not match the functional success in all cases. Retinal re-detachment remained the most common complication after the silicone oil removal.</p>","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":"17 34","pages":"36-44"},"PeriodicalIF":0.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bleb-related Infection following Trabeculectomy.","authors":"Madhu Thapa, Pragati Gautam, Sareena Pachai","doi":"10.3126/nepjoph.v17i1.69157","DOIUrl":"10.3126/nepjoph.v17i1.69157","url":null,"abstract":"<p><strong>Introduction: </strong>Bleb-related endophthalmitis after trabeculectomy is a rare but sight threatening complication. Thin walled blebs, occurring after adjunctive use of antimetabolite like mitomycin C and 5-flurouracil, is an important risk factor for bleb-related infections.</p><p><strong>Case: </strong>Forty-five years old one-eyed male had undergone trabeculectomy in past, had presented with diminution of vision, pain, photophobia in his seeing eye.</p><p><strong>Observation: </strong>On examination, best corrected visual acuity was 5/60, thin walled avascular bleb with congested conjunctiva, minimal hypopyon, pupil had fibrinous exudate and vitreous reaction. He was diagnosed as bleb-related endophthalmitis. He improved after intra-vitreal and topical antibiotics Conclusion: Bleb-related infections can be controlled if diagnosed and treated on time.</p>","PeriodicalId":44759,"journal":{"name":"Nepalese Journal of Ophthalmology","volume":"17 33","pages":"66-71"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}