Annals of Geriatric Medicine and Research最新文献_第6页

Psychomotor Symptoms, Cognitive Impairments, and Suicidal Thoughts after COVID-19 Infection: A Case Report and Possible Allostatic Mechanism. COVID-19 感染后的精神运动症状、认知障碍和自杀念头：病例报告和可能的异位机制。

IF 2.8

Annals of Geriatric Medicine and Research Pub Date : 2024-09-01 Epub Date: 2024-05-17 DOI: 10.4235/agmr.24.0037

Ying Lin, Chen Lin, Jason Hong-Yi Chang, Dai-Lun Chiang, Feipei Lai, Chen-Ju Lin

引用次数: 0

IF 2.8

Annals of Geriatric Medicine and Research Pub Date : 2024-09-01 Epub Date: 2024-05-28 DOI: 10.4235/agmr.24.0025

Takuaki Tani, Watanabe Kazuya, Ryo Onuma, Kiyohide Fushimi, Shinobu Imai

{"title":"Age-Related Differences in the Effectiveness of Rehabilitation to Improve Activities of Daily Living in Patients with Stroke: A Cross-Sectional Study.","authors":"Takuaki Tani, Watanabe Kazuya, Ryo Onuma, Kiyohide Fushimi, Shinobu Imai","doi":"10.4235/agmr.24.0025","DOIUrl":"10.4235/agmr.24.0025","url":null,"abstract":"Background: This study aimed to reveal differences in the effectiveness of rehabilitation in improving activities of daily living (ADL) in patients with acute stroke across age groups and propose age-appropriate rehabilitation strategies.Methods: This observational study analyzed nationwide administrative data of inpatients admitted to hospitals with acute stroke between April 1, 2018, and March 31, 2020. The data included the average length of daily rehabilitation sessions, weekly frequency of rehabilitation sessions, and initiation of rehabilitation within 3 days. The primary outcome was the improvement in the Barthel Index (BI) score from admission to discharge. We classified the patients based on age and analyzed improvements in ADL according to rehabilitation characteristics.Results: An increased daily rehabilitation dose was associated with improved ADL, except in patients aged <65 years (risk ratio [95% confidence interval] in the 65-74, 75-85, and ≥85 years age groups: 1.20 [1.14‒1.27], 1.21 [1.15‒1.27], and 1.43 [1.34‒1.53], respectively; all p<0.001 vs. <65 years: 1.05 [0.98‒1.12]; p=0.18). A rehabilitation frequency of seven sessions per week was associated with improved ADL in the 75-85 years and ≥85 years age groups (1.06 [1.02‒1.10] and 1.08 [1.03‒1.13], respectively; both p<0.001). The effects of initiating rehabilitation within 3 days on ADL post-admission did not differ across age groups.Conclusion: Increasing the daily dose of rehabilitation was significantly associated with improved ADL in all age groups while increasing the frequency of rehabilitation per week improved ADL in older and very old patients.","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"257-265"},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11467512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141157494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between Drug Therapy and Risk of Incident Frailty: A Systematic Review. 药物治疗与罹患虚弱症风险的关系：系统综述。

IF 2.8

Annals of Geriatric Medicine and Research Pub Date : 2024-09-01 Epub Date: 2024-05-17 DOI: 10.4235/agmr.24.0034

Saran Thanapluetiwong, Tanchanok Chattaris, Sandra Miao Shi, Chan Mi Park, Stephanie Denise M Sison, Dae Hyun Kim

引用次数: 0

Association of Serum Lactate Levels Measured in the Emergency Department with 30-Day Mortality in Older Patients with Unilateral Hip Fractures. 急诊科测量的血清乳酸水平与单侧髋部骨折老年患者 30 天死亡率的关系

IF 2.8

Annals of Geriatric Medicine and Research Pub Date : 2024-09-01 Epub Date: 2024-07-02 DOI: 10.4235/agmr.24.0011

Handan Özen Olcay, Emine Emektar, Zeynep Saral Öztürk, Sedat Akkan, Yunsur Çevik

{"title":"Association of Serum Lactate Levels Measured in the Emergency Department with 30-Day Mortality in Older Patients with Unilateral Hip Fractures.","authors":"Handan Özen Olcay, Emine Emektar, Zeynep Saral Öztürk, Sedat Akkan, Yunsur Çevik","doi":"10.4235/agmr.24.0011","DOIUrl":"10.4235/agmr.24.0011","url":null,"abstract":"Background: Hip fractures are frequent injuries in older patients and are associated with high mortality rates. This study assessed the association between serum lactate level and 30-day mortality in older patients with unilateral hip fractures and examined the prognostic value of this association on the clinical outcomes of these patients.Methods: This retrospective, single-center study included patients aged ≥65 years admitted to the emergency department due to low-energy trauma and diagnosed with unilateral hip fracture upon admission. The additional inclusion criteria were patients with independent ambulation or walker or cane assistance before the injury, with available data on serum lactate levels on venous blood gas analysis, and who underwent surgery.Results: Among the 330 included patients, 30.9% experienced postoperative complications and 10.3% died within 30 days. Using a lactate cut-off value of 2 mmol/L to distinguish between living and deceased patients, the sensitivity and specificity were 41% and 88%, respectively. Multivariate logistic regression analysis revealed that high lactate and low albumin levels and male sex were associated with mortality.Conclusion: Identifying risk factors for mortality in geriatric patients with hip fractures is important. Male sex, low albumin levels, and particularly increased lactate levels were independent predictors of short-term mortality in these patients.","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"301-306"},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11467522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Body Adiposity Index as a Predictor of Body Fat in an Oldest Old and Independent Cohort of Brazilian Older Adults. 身体肥胖指数 (BAI) 作为巴西高龄独立老人队列中身体脂肪的预测指标。

IF 2.8

Annals of Geriatric Medicine and Research Pub Date : 2024-09-01 Epub Date: 2024-05-17 DOI: 10.4235/agmr.24.0008

Evelyn Dearo Spinoza, Flavia Kurebayashi Fonte, Vanessa Amarante Carvalho, Regiane Aparecida Dos Santos, Gisele W B Colleoni, Maysa Seabra Cendoroglo

{"title":"Body Adiposity Index as a Predictor of Body Fat in an Oldest Old and Independent Cohort of Brazilian Older Adults.","authors":"Evelyn Dearo Spinoza, Flavia Kurebayashi Fonte, Vanessa Amarante Carvalho, Regiane Aparecida Dos Santos, Gisele W B Colleoni, Maysa Seabra Cendoroglo","doi":"10.4235/agmr.24.0008","DOIUrl":"10.4235/agmr.24.0008","url":null,"abstract":"Background: Anthropometry and body mass index (BMI) do not assess body composition or its distribution in older adults; thus, individuals may have different fat percentages but similar BMI values. The body adiposity index (BAI) was recently proposed as a feasible and inexpensive method for estimating the percentage of body fat based on measurements of hip circumference and height. The present study evaluated whether BAI and BMI are useful alternatives to dual-energy X-ray absorptiometry (DXA), which is rarely used in clinical practice, for predicting body fat in independent long-lived older adults.Methods: In this cross-sectional study, we used DXA to calculate the percentage of body fat, which was compared with BAI and BMI values. We performed Pearson correlation analyses and used Cronbach's alpha, described by Bland and Altman, to compare the reliability between the indexes.Results: Among 157 evaluated individuals (73.2% women, mean age 87±3.57 years), men had a lower percentage of total fat, as assessed by DXA, and lower BAI indices than women. The correlation between BAI and DXA was moderate (r=0.59 for men and r=0.67 for women, p<0.001). We confirmed the reliability based on Cronbach's alpha coefficients of 0.67 in men and 0.77 in women. We also observed that the BAI was strongly positively correlated with BMI in both men and women.Conclusion: The BAI, used in combination with BMI, can be an alternative to DXA for the assessment of body fat in the oldest old in clinical practice, mainly women, and can be used to add information to BMI.","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"284-290"},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140959192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Geriatric Nutritional Risk Index as a Possible Predictor of Decline in Kidney Function in Older People. 老年营养风险指数可预测老年人肾功能衰退。

IF 2.8

Annals of Geriatric Medicine and Research Pub Date : 2024-06-01 Epub Date: 2024-02-29 DOI: 10.4235/agmr.23.0215

Sukmin Yoon, Nak Gyeong Ko, Yu-Ji Lee

{"title":"Geriatric Nutritional Risk Index as a Possible Predictor of Decline in Kidney Function in Older People.","authors":"Sukmin Yoon, Nak Gyeong Ko, Yu-Ji Lee","doi":"10.4235/agmr.23.0215","DOIUrl":"10.4235/agmr.23.0215","url":null,"abstract":"Background: The Geriatric Nutritional Risk Index (GNRI) is associated with morbidity and mortality in older individuals. Our study explored the relationship between GNRI, decline in kidney function, and all-cause mortality in older individuals.Methods: This retrospective cohort study analyzed data from participants aged ≥60 years who underwent a general health checkup between 2002 and 2018. The primary exposure was the GNRI, divided into quartiles. The primary and secondary outcomes were a decline in kidney function assessed using the 5-year estimated glomerular filtration rate (eGFR) and all-cause mortality, respectively.Results: The analysis included a total of 1,599 participants (median age, 63 years; interquartile range [IQR], 61-67; 54% males). The mean±standard deviation of GNRI was 114±7. Compared with the highest GNRI quartile, the lower GNRI quartiles were associated with steeper 5-year slopes in eGFR, with a fully adjusted beta coefficient and 95% confidence intervals (CIs) of -0.50 (-0.86, -0.14), -0.29 (-0.63, 0.05), and -0.19 (-0.53, 0.14) for the first, second, and third GNRI quartiles, respectively. The median follow-up duration was 7.4 years (IQR, 4.6-12.4). During this period, we identified 108 deaths (7.8 per 1,000 person-years). The first GNRI quartile was associated with all-cause mortality compared to the highest GNRI quartile (hazard ratio of 2.20; 95% CI 1.23, 3.95).Conclusion: Nutritional status, as evaluated using the GNRI, was associated with 5-year changes in kidney function and all-cause mortality in older individuals.","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"164-170"},"PeriodicalIF":2.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139991457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing Footwear Safety for Fall Prevention in Older Adults: A Comprehensive Review of Design Features. 提高鞋类安全性，预防老年人跌倒：设计特点综合评述。

IF 2.8

Annals of Geriatric Medicine and Research Pub Date : 2024-06-01 Epub Date: 2024-01-22 DOI: 10.4235/agmr.23.0167

In-Ju Kim, Fatma Hegazy

{"title":"Enhancing Footwear Safety for Fall Prevention in Older Adults: A Comprehensive Review of Design Features.","authors":"In-Ju Kim, Fatma Hegazy","doi":"10.4235/agmr.23.0167","DOIUrl":"10.4235/agmr.23.0167","url":null,"abstract":"Background: Falls are a global concern affecting people of all ages; however, older adults are particularly vulnerable to age-related factors and foot-related issues. Footwear is critical for preventing falls, as it provides stability and protection against slips, trips, and falls (STFs). However, a significant gap exists in the systematic exploration of the safety aspects of footwear design for fall prevention in older adults.Methods: This comprehensive review applied a meticulous search strategy encompassing prominent databases, including Google Scholar, ScienceDirect, SCOPUS, MEDLINE, ResearchGate, and PubMed. This review synthesized and analyzed existing research to bridge knowledge gaps and provide insights into optimal footwear choices for older adults in terms of design features such as fit, fixation, heel height, collar height, slip resistance, and sole/insole hardness.Results: The results underscore the importance of specific design features for preventing falls among older adults. A proper fit, secure fixation, appropriate heel and collar heights, slip resistance, and sole/insole hardness significantly contributed to fall prevention. These findings offer valuable guidance for optimizing footwear designs to enhance comfort, stability, and safety in the daily lives of older individuals.Conclusion: This comprehensive review fills a critical knowledge gap regarding the safety of footwear designs for fall prevention in older adults. The identified design features play a vital role in reducing the risk of falls and offer practical recommendations for the development of safer footwear. Ultimately, this study contributes to the existing knowledge base and supports efforts to prevent STFs in older adults through improved footwear design.","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"121-133"},"PeriodicalIF":2.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139513951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predicting Mortality Risks Using Body Mass Index and Weight Loss at Admission in Patients with Heart Failure. 利用入院时的体重指数和体重下降情况预测心力衰竭患者的死亡风险。

IF 2.8

Annals of Geriatric Medicine and Research Pub Date : 2024-06-01 Epub Date: 2024-03-13 DOI: 10.4235/agmr.23.0213

Yuria Ishida, Keisuke Maeda, Kenta Murotani, Akio Shimizu, Junko Ueshima, Ayano Nagano, Tatsuro Inoue, Naoharu Mori

{"title":"Predicting Mortality Risks Using Body Mass Index and Weight Loss at Admission in Patients with Heart Failure.","authors":"Yuria Ishida, Keisuke Maeda, Kenta Murotani, Akio Shimizu, Junko Ueshima, Ayano Nagano, Tatsuro Inoue, Naoharu Mori","doi":"10.4235/agmr.23.0213","DOIUrl":"10.4235/agmr.23.0213","url":null,"abstract":"Background: The association of the combination of body mass index (BMI) and weight change at admission with prognoses in patients with heart failure (HF) is unclear. Therefore, we investigated whether BMI and weight changes at admission affect mortality in patients with HF.Methods: This retrospective cohort study lasted 99 months, starting in April 2014, and included 4,862 patients with HF from a Japanese real-world database. Cubic and thin-plate smoothing spline analyses were performed to investigate the association of BMI and weight changes with mortality. The percentage weight change was calculated every 6 months. The study outcome was the presence or absence of death.Results: The patients' mean age was 81.5±9.6 years, and 1,239 (25.5%) patients died. Cubic spline analysis revealed a negative correlation of BMI with mortality hazard ratio (HR) (BMI of 18.5 kg/m2 and 25 kg/m2; HR=1.3 [1.2-1.4] and 0.8 [0.7-0.9], respectively). Cubic spline analysis of weight change showed that weight loss tended to increase the mortality HR (each 6% decrease in weight change rate was associated with a 1.1 times higher mortality risk (95% CI [1.0-1.2]) Thin-plate smoothing spline analysis showed that the odds ratio (OR) negatively correlated with BMI (1-year mortality: BMI of 18.5 kg/m2, 22 kg/m2, and 25 kg/m2; OR at 0% weight change=1.5, 1.0, and 0.7, respectively; 2-year mortality: BMI=18.5 kg/m2, 22 kg/m2, and 25 kg/m2; OR at 0% weight change=1.4, 0.9, and 0.7, respectively).Conclusion: A low BMI in patients with HF was associated with a higher risk of mortality. Weight loss in patients, regardless of BMI, was associated with a higher OR for mortality.","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"171-177"},"PeriodicalIF":2.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140111819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of Olfactory and Gustatory Function with Memory among Community-Dwelling Independent Older Adults. 居住在社区的独立老年人的嗅觉和味觉功能与记忆力的关系。

IF 2.8

Annals of Geriatric Medicine and Research Pub Date : 2024-06-01 Epub Date: 2024-03-13 DOI: 10.4235/agmr.23.0217

Hyuma Makizako, Yuki Nakai, Shoma Akaida, Yoshiaki Taniguchi, Takaki Miwa, Shigeto Morimoto

{"title":"Association of Olfactory and Gustatory Function with Memory among Community-Dwelling Independent Older Adults.","authors":"Hyuma Makizako, Yuki Nakai, Shoma Akaida, Yoshiaki Taniguchi, Takaki Miwa, Shigeto Morimoto","doi":"10.4235/agmr.23.0217","DOIUrl":"10.4235/agmr.23.0217","url":null,"abstract":"Background: This study examined the association between memory function and reduced olfactory and gustatory function among independent community-dwelling older adults.Methods: This cross-sectional study included 127 older adults (65.4% women). We assessed their memory, odor, and taste identification skills. Open essence (OE) test and taste strips (TS) were used to identify hyposmia (OE test ≤6) and hypogeusia (TS test ≤8), respectively.Results: Participants with severe hyposmia had significantly poorer memory functions compared to participants without severe hyposmia. After adjusting for covariates, multivariate logistic regression models revealed a significant association between immediate recognition performance and a decreased likelihood of severe hyposmia (odds ratio=0.65; 95% confidence interval 0.47-0.90). We observed no significant association between taste function and memory.Conclusion: Memory function may be associated with olfactory impairment in older adults.","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"178-183"},"PeriodicalIF":2.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140111817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Podocyte Disease Following Treatment with Intravenous Ibandronate in an Older Patient. 一名老年患者接受伊班膦酸钠静脉注射治疗后出现荚膜细胞病变。

IF 2.8

Annals of Geriatric Medicine and Research Pub Date : 2024-06-01 Epub Date: 2024-02-22 DOI: 10.4235/agmr.23.0195

Ye Rin Chung, Hyun Soon Lee, Dong Young Lee, Sang Hee Lee, Jin Seon Jeong, Beom Kim

{"title":"Podocyte Disease Following Treatment with Intravenous Ibandronate in an Older Patient.","authors":"Ye Rin Chung, Hyun Soon Lee, Dong Young Lee, Sang Hee Lee, Jin Seon Jeong, Beom Kim","doi":"10.4235/agmr.23.0195","DOIUrl":"10.4235/agmr.23.0195","url":null,"abstract":"Bisphosphonates are commonly used to treat osteoporosis. While renal toxicity is common with pamidronate and zoledronate, few ibandronate-related cases are reported. We describe a rare case of ibandronate-associated nephrotoxicity. An 88-year-old woman was admitted for edema. She had been receiving intravenous ibandronate treatment for postmenopausal osteoporosis and had no other diagnosed diseases. She was presented with proteinuria, hypoalbuminemia (1.9 g/dL), and an elevated serum creatinine level (1.8 mg/dL). Renal biopsy revealed podocyte disease, favoring a diagnosis of focal segmental glomerulosclerosis. She was treated with diuretics, tacrolimus, and fimasartan. Steroids were avoided due to severe osteoporosis. Three months later, the edema had subsided and the laboratory findings had improved (serum albumin 3.5 g/dL, serum creatinine 0.97 mg/dL). This case emphasizes the importance of careful monitoring of proteinuria and renal function during ibandronate treatment. In older adult patients, kidney biopsy and immunosuppressive treatment may be considered based on physical activity and underlying diseases.","PeriodicalId":44729,"journal":{"name":"Annals of Geriatric Medicine and Research","volume":" ","pages":"228-230"},"PeriodicalIF":2.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0