Journal of Public Health in Africa最新文献

{"title":"Killer cell immunoglobulin-like receptor alleles influence susceptibility to occult hepatitis B infection in West African population.","authors":"Momeiyi Michee Bazie,&nbsp;Florencia Wendkuuni Djigma,&nbsp;Mahamoudou Sanou,&nbsp;Pegdwendé Abel Sorgho,&nbsp;Abdoul Karim Ouattara,&nbsp;Dorcas Obiri-Yeboah,&nbsp;Nadège Kapieko,&nbsp;Herman Karim Sombie,&nbsp;Prosper Bado,&nbsp;Edwige Tampoubila Yelemkoure,&nbsp;Isabelle Touwendpoulimdé Kiendrebeogo,&nbsp;Marius Bolni Nagalo,&nbsp;Albert Théophane Yonli,&nbsp;Jacques Simpore","doi":"10.4081/jphia.2023.2586","DOIUrl":"https://doi.org/10.4081/jphia.2023.2586","url":null,"abstract":"<p><p>Occult hepatitis B infection (OBI) is a public health problem in Burkina Faso. OBI represents a risk factor for the development of cirrhosis and hepatocellular carcinoma (HCC). OBI could be due to mutant viruses undetectable by HBsAg assays or a strong suppression of viral replication and gene expression under the pression of the host immune system. To investigate the role of killer cell immunoglobulin-like receptor (KIR) gene polymorphisms in patients with OBI in Burkina Faso compared to healthy and chronic hepatitis B subjects. A total of 286 participants was recruited, including 42 cases of OBI, 110 cases of chronic hepatitis B and 134 HBV negative subjects. SSP-PCR was performed to search for the presence of KIR genes. The HBV viral load was determined by qPCR. The frequencies of the activator gene <i>KIR2DS5</i> (P=0.045) and the pseudogene <i>KIR2DP1</i> (P<0.001) in patients with OBI were higher than those in patients with chronic hepatitis B. These genes are associated with susceptibility of occult hepatitis B infection. The frequencies of the inhibitory KIR gene <i>KIR2DL3</i> (P=0.01) of patients with occult hepatitis B were lower than those in chronic hepatitis B patients. This gene <i>KIR2DL3</i> is associated with protection against occult hepatitis B infection. Also, the frequencies of the inhibitory KIR genes <i>KIR2DL2</i> (P<0.001), <i>KIR2DL3</i> (P<0.001) and activators <i>KIR2DS2</i> (P<0.001) in chronic hepatitis B patients were higher compared to the frequencies of the KIR genes in healthy subjects. These genes <i>KIR2DL3</i>, <i>KIR2DL5</i> (<i>A</i>, <i>B</i>), <i>KIR3DL3</i>, <i>KIR3DS1</i>, <i>KIR2DL2</i> and <i>KIR2DS2</i> are thought to be genes associated with the susceptibility to OBI. The <i>KIR2DS5</i> and <i>KIR2DP1</i> genes could be associated with susceptibility to OBI. As for the KIR gene <i>KIR2DL3</i> could be associated with protection against occult hepatitis B infection.</p>","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"14 9","pages":"2586"},"PeriodicalIF":0.8,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food insecurity increases risk of depression and anxiety among women in Senegal living with diabetes and/or hypertension.","authors":"Rachel P Allred, Ndèye Aminata Mbaye, Fatoumata Diagne, Sheryl A McCurdy, Melissa B Harrell, Emma Nelson Bunkley","doi":"10.4081/jphia.2023.2467","DOIUrl":"https://doi.org/10.4081/jphia.2023.2467","url":null,"abstract":"<p><p>Food insecurity affects close to half the population of Senegal, West Africa, a country simultaneously affected by the ongoing global diabetes pandemic. Diabetes and food insecurity are associated with adverse mental health, yet research exploring the relationship between chronic physical illness, food insecurity, and mental illness in Senegal is currently lacking. The objective of this study was to investigate the association between food insecurity and depression and anxiety, separately, in Senegalese women living with diabetes and hypertension. Food insecurity was measured using the Household Food Insecurity Access Scale. Occurrence of depression and anxiety symptoms was assessed using the Modified Hopkins Symptoms Checklist Survey (HSCL-25). A sensitivity analysis examining the relationship between food insecurity and depression and anxiety was performed by comparing two previously validated cutoff values (1.75 and 2.25) on the HSCL-25. Most participants (83%) had some level of food insecurity. More than 80% of the sample were depressed or anxious using 1.75 as the cutoff, while 42 and 60% were depressed or anxious, respectively, using 2.25 as the cutoff. Food insecurity increased relative risk for depression (RRR: 1.40, 95% CI: 1.05-1.31, 1.75 as cutoff; RRR: 1.06, 95% CI: 0.99-1.14, 2.25 as cutoff) and anxiety (RRR: 1.17, 95% CI: 1.05-1.31, 1.75 as cutoff; RRR: 1.11, 95% CI: 1.04-1.19, 2.25 as cutoff). These findings demonstrate that among populations suffering from diabetes and hypertension, food insecurity is a modifiable risk factor for depression and anxiety and a potential intervention target in this setting.</p>","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"14 10","pages":"2467"},"PeriodicalIF":0.8,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138463301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is antero-lateral complex of knee joint of critical importance in restoring rotational instability in patients with anterior cruciate ligament tear?","authors":"Abhishek Kumar Mishra, Sundip Charmode, Sudhir Kushwaha, Vishwa Chauhan, Simmi Mehra, Vivek Mishra","doi":"10.4081/jphia.2023.2696","DOIUrl":"https://doi.org/10.4081/jphia.2023.2696","url":null,"abstract":"<p><p>Antero-lateral ligament complex (ALC) is a vital structure for maintaining rotational stability of the knee. Evaluation of ALC radiologically (MRI) is still unpopular in setting of anterior cruciate ligament injury. A dire necessity exists for the orthopedic surgeons in outdoor patient department settings to rule out involvement of ALC. So, that it can be addressed during operating for Anterior Cruciate Ligament injury. The authors have formulated an algorithm on a personal level and have implemented this screening program and initiated screening of young to middle aged patients reporting with rotational knee instability for ALC involvement before recommending final operative plan. This screening program which uses specifically devised physical tests have significantly reduced the number of underdiagnosed Antero Lateral Ligament tear.</p>","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"14 10","pages":"2696"},"PeriodicalIF":0.8,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138463319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respiratory symptoms and pulmonary function impairment among textile industry workers in Alexandria, Egypt.","authors":"Noha Elshaer, Nermin Foda, Sameh Shehata","doi":"10.4081/jphia.2023.2741","DOIUrl":"https://doi.org/10.4081/jphia.2023.2741","url":null,"abstract":"<p><p>Occupational exposure to cotton dust is still an important cause of respiratory problems in textile workers particularly in less developed countries like Egypt. Evaluate respiratory symptoms and diseases, and pulmonary function pattern among Egyptian textile workers. Cross sectional comparative study was conducted from December 2019 to September 2020 in a textile factory in Egypt; 364 male workers (184 cotton dust exposed workers, and 180 unexposed workers) were included. Participants were subjected to an interviewing questionnaire, British Medical Research Council questionnaire, anthropometric measurements, pulmonary function tests, and byssinosis grading format. Descriptive and analytic statistics were conducted. Chronic cough, phlegm production, and shortness of breath grade I, II and III were more reported in cotton dust exposed workers than unexposed workers (P#x003C;0.01, P#x003C;0.01, and P=0.02, respectively). Prevalence of chronic bronchitis was significantly higher among cotton dust exposed workers (12%) than unexposed workers (3.9%) (P#x003C;0.01). The mean percent predicted values of lung function indices reflecting large-1irway function (VC, FVC, FEV₁, FEV₁%, PEFR, and FEF₇₅) were significantly lower in cotton dust exposed workers (P#x003C;0.01). Prevalence of byssinosis was 22.8%. Workers with byssinosis had significantly higher prevalence of respiratory symptoms, chronic bronchitis, cross-shift reduction in PEFR and significant decrease in mean percent predicted values of FVC, FEV₁, PEFR, FEF₇₅, and FEF₅₀ than workers without byssinosis. This study revealed a substantial association between cotton dust exposure at work and respiratory symptoms and morbidity. Regular measurement of cross shift change in PEFR is recommended among exposed workers for early diagnosis of byssinosis.</p>","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"14 10","pages":"2741"},"PeriodicalIF":0.8,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138463334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A prize for global health in the name of Rudolf Virchow.","authors":"Tolu Oni,&nbsp;Detlev Ganten,&nbsp;Beate Kampmann,&nbsp;Roland Göhde,&nbsp;Ole Petter Ottersen","doi":"10.4081/jphia.2023.2862","DOIUrl":"https://doi.org/10.4081/jphia.2023.2862","url":null,"abstract":"<jats:p>N/A</jats:p>","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"14 9","pages":"2862"},"PeriodicalIF":0.8,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional National Public Health Institutes are critical for the health security of Africa.","authors":"Haftom Taame, Nicaise Ndembi, Alain Ngashi Ngongo, Tajudeen Raji, Jean Kaseya","doi":"10.4081/jphia.2023.2863","DOIUrl":"https://doi.org/10.4081/jphia.2023.2863","url":null,"abstract":"Not available","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"14 9","pages":"2863"},"PeriodicalIF":0.8,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71522898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitigating household psychosocial and economic impact of coronavirus pandemic in Mathare slums, Nairobi, Kenya: an initiative by the German doctors in Kenya.","authors":"Alloysius Omoto, George Audi, Samira Hassan","doi":"10.4081/jphia.2023.2803","DOIUrl":"10.4081/jphia.2023.2803","url":null,"abstract":"<p><p>The Psychosocial and Economic Impact of COVID-19 Pandemic in Mathare slums were adverse which necessitated mitigation strategies to be employed to cushion the most vulnerable and help them cope with the new 'state of affairs'. The pandemic was characterized by a surge in the respiratory infections, unemployment, households going hungry, gender-based violence in families, child abuse cases and increased rates of teenage pregnancy. Retrospective case study design was employed; secondary data from hospital departments were extracted for analysis from March 2020 to December 2021. Interventions in focus were health service provision, Gender based and child abuse services, food distribution, wet-feeding program, business grants and house rent grants. The most common burden faced by Mathare residents was food insecurity which was mitigated by giving 9,423 Patients' food baskets while 1,423 patients enrolled to the wet feeding program. Gender Based Violence services provided doubled in the year 2021 with physical and emotional violence being more common than sexual violence which was at 6.2%. Child abuse services were provided more in the year 2020 and 96 teenage mothers were assisted to go back to school. About 158 families received rent grants; which was a 30.4% increase from the year 2020. There was a 75.5% increase in the year 2021 of residents who received business grants. In a pandemic the effects are beyond health hence it is necessary to manage patients comprehensively using a multi-sectorial approach. However it is important to put regulations to avoid overdependence.</p>","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"14 10","pages":"2803"},"PeriodicalIF":0.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138463322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmaceutical Manufacturing Plan for Africa is critical for pandemic preparedness, prevention and response.","authors":"Michael Mynhardt,&nbsp;Nicaise Ndembi","doi":"10.4081/jphia.2023.2861","DOIUrl":"https://doi.org/10.4081/jphia.2023.2861","url":null,"abstract":"Not available","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"14 9","pages":"2861"},"PeriodicalIF":0.8,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of pregnant women regarding tobacco and alcohol use in pregnancy at Mariental clinic, Hardap region: a quantitative study.","authors":"Selma Hamutenya, Emma Maano Nghitanwa, Marian Sankombo","doi":"10.4081/jphia.2023.2435","DOIUrl":"https://doi.org/10.4081/jphia.2023.2435","url":null,"abstract":"<p><p>Globally, alcohol and tobacco use during pregnancy is a challenge and linked to negative effects on health and wellbeing on both mother and the fetus. To investigate the knowledge of pregnant women attending antenatal care at Mariental clinic regarding the use of tobacco and alcohol in pregnancy. A quantitative approach with descriptive, cross-sectional, analytical design was used. The population were all pregnant women attending antenatal care at Mariental clinic. Systematic sampling method was used to select the sample of 224 pregnant women. Data was collected using a self-administered questionnaire that collected information on sociodemographic data and knowledge on tobacco and alcohol use. Data was analysed using Statistical Package of the Social Sciences (SPSS) version 27. Descriptive statistics was utilized to generatee frequencies and percentages. Fisher's Exact test at 0.05 alpha level was used to determine the association between variables. The mean age was 28.8 with a standard deviation of 6.9 years. Most participants, 43.6% were aged between 18 and 24 years. Majority, 88.15% were in third trimester of pregnancy, 73% were single, and unemployed. Most participants 78.7% have a high level of knowledge regarding the use of alcohol during pregnancy and 70.1% have higher level of knowledge regarding tobacco use during pregnancy. No association was found on the level of knowledge on alcohol and tobacco use during pregnancy and socio demographic characteristics as all variables show a P-value of more than 0.05. Participants have higher knowledge on alcohol and tobacco use during pregnancy.</p>","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"14 10","pages":"2435"},"PeriodicalIF":0.8,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138465532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"We must revise the current logic to protect our humanity from Infectious disease outbreaks.","authors":"Mosoka P Fallah","doi":"10.4081/jphia.2023.2829","DOIUrl":"https://doi.org/10.4081/jphia.2023.2829","url":null,"abstract":"Not available","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"14 9","pages":"2829"},"PeriodicalIF":0.8,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}