Delia D Djuicy, Benjamin Selekon, Christian Malaka, Aboubacar Soumah, Edgar Adjogoua, Hervé Kadjo, Offianan A Toure, Pierre Roques, Solène Grayo, Noël Tordo, Ousmane Faye, Abdourahmane Sow, François-Xavier Berthet, Vincent Lacoste, Soa Fy Andriamandimby, Hamidou L Ramatoulaye, Adamou Lagare, Haoua S Sabo, Ella Farra, Sandra G Ouangole, Gide Martial Yonga Wansi, Dieudonne G Essima, Jules Landry Mounchili Mouliem, Herman Philipe Nfombouot Njitoyap, Sandrine O Nkoum Kyane, Syndou Meite, Sara I Eyangoh, Mirdad Kazanji, Yap Boum, Rebecca Grais, Emmanuel Nakoune, Richard Njouom, Amadou A Sall
{"title":"Strengthening Africa's resilience to Mpox: Preparedness and response initiatives of the Pasteur network.","authors":"Delia D Djuicy, Benjamin Selekon, Christian Malaka, Aboubacar Soumah, Edgar Adjogoua, Hervé Kadjo, Offianan A Toure, Pierre Roques, Solène Grayo, Noël Tordo, Ousmane Faye, Abdourahmane Sow, François-Xavier Berthet, Vincent Lacoste, Soa Fy Andriamandimby, Hamidou L Ramatoulaye, Adamou Lagare, Haoua S Sabo, Ella Farra, Sandra G Ouangole, Gide Martial Yonga Wansi, Dieudonne G Essima, Jules Landry Mounchili Mouliem, Herman Philipe Nfombouot Njitoyap, Sandrine O Nkoum Kyane, Syndou Meite, Sara I Eyangoh, Mirdad Kazanji, Yap Boum, Rebecca Grais, Emmanuel Nakoune, Richard Njouom, Amadou A Sall","doi":"10.4102/jphia.v16i1.1026","DOIUrl":"10.4102/jphia.v16i1.1026","url":null,"abstract":"","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"16 1","pages":"1026"},"PeriodicalIF":0.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gloria P Gómez-Pérez, Shem O O Sam, Nicaise Ndembi, Tobias F Rinke de Wit
{"title":"Mpox after COVID-19 in Africa: Different epidemic, similar challenges.","authors":"Gloria P Gómez-Pérez, Shem O O Sam, Nicaise Ndembi, Tobias F Rinke de Wit","doi":"10.4102/jphia.v16i1.874","DOIUrl":"10.4102/jphia.v16i1.874","url":null,"abstract":"<p><p>Africa faces again a new outbreak of mpox, heavily burdening the Democratic Republic of Congo (DRC). Factors such as biological and ecological changes in the virus, waning of immunity to smallpox, socio-economic challenges, and global economic strain are fueling this epidemic. To analyse the drivers of the mpox outbreak in DRC, review the international and local response, and draw lessons from the COVID-19 pandemic to propose strategies for building epidemic-resilient healthcare systems in the region. The focus is on the DRC, where the mpox epidemic is concentrated, and the broader African region, assessing both rural and urban healthcare contexts. This study synthesises epidemiological data, global health policies, and local health system responses. Key insights are drawn from COVID-19 case studies, and assessment of access to diagnostics and vaccines. The DRC hosts over 95% of Africa's mpox cases, with significant challenges in human-wildlife interactions, poverty, and weakened healthcare systems exacerbated by COVID-19. Vaccine shortages, diagnostic delays, and uneven international support reflect a repeat of challenges seen during COVID-19. Localised vaccine and diagnostics production, improved risk communication, and digital health tools are highlighted as critical interventions. An epidemic-resilient healthcare framework, leveraging local production of medical products, regulatory empowerment, and real-time data collection, is essential for controlling mpox and future outbreaks. This study underscores the need for African-led solutions, addressing socio-economic drivers, enhancing local capacities, and fostering international solidarity to mitigate future epidemic threats.</p>","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"16 1","pages":"874"},"PeriodicalIF":0.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Solomon F Woldetsadik, Ebenezer O Daniel, John Masina, Joseph C Okeibunor, Samuel Boland, Hilary K Njenge, Nicaise Ndembi, Ngashi Ngongo, Otim P C Ramadan, Fiona Braka, Abdou S Gueye
{"title":"Case management of mpox: Where we are and where we desire to be.","authors":"Solomon F Woldetsadik, Ebenezer O Daniel, John Masina, Joseph C Okeibunor, Samuel Boland, Hilary K Njenge, Nicaise Ndembi, Ngashi Ngongo, Otim P C Ramadan, Fiona Braka, Abdou S Gueye","doi":"10.4102/jphia.v16i1.1228","DOIUrl":"10.4102/jphia.v16i1.1228","url":null,"abstract":"","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"16 1","pages":"1228"},"PeriodicalIF":0.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ngashi Ngongo, Nicaise Ndembi, Mosoka Fallah, Wessam Mankoula, Merawi A Tegegne, Moréniké Oluwátóyìn Foláyan, Jean Kaseya
{"title":"Unified continental approach to mpox preparedness and response: A model for Africa's future outbreaks.","authors":"Ngashi Ngongo, Nicaise Ndembi, Mosoka Fallah, Wessam Mankoula, Merawi A Tegegne, Moréniké Oluwátóyìn Foláyan, Jean Kaseya","doi":"10.4102/jphia.v16i1.877","DOIUrl":"10.4102/jphia.v16i1.877","url":null,"abstract":"","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"16 1","pages":"877"},"PeriodicalIF":0.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ngashi Ngongo, Nicaise Ndembi, Tajudeen Raji, Mosoka Fallah, Wessam Mankoula, Jean-Marie Vianny Yameogo, Fiona Braka, Abdou Salam Gueye, Matshidiso R Moeti, Jean Kaseya
{"title":"Building systems' resilience in the mpox outbreak response in Africa.","authors":"Ngashi Ngongo, Nicaise Ndembi, Tajudeen Raji, Mosoka Fallah, Wessam Mankoula, Jean-Marie Vianny Yameogo, Fiona Braka, Abdou Salam Gueye, Matshidiso R Moeti, Jean Kaseya","doi":"10.4102/jphia.v16i1.875","DOIUrl":"10.4102/jphia.v16i1.875","url":null,"abstract":"","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"16 1","pages":"875"},"PeriodicalIF":0.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicaise Ndembi, Bethanie Rammer, Joseph Fokam, Uttam Dinodia, Sofonias K Tessema, Jean Philbert Nsengimana, Sarah Mwangi, Edem Adzogenu, Landry Tsague Dongmo, Bleddyn Rees, Brian O'Connor, Trevor A Crowell, Wilmot James, Vittorio Colizzi, Ngashi Ngongo, Jean Kaseya
{"title":"Integrating artificial intelligence into African health systems and emergency response: Need for an ethical framework and guidelines.","authors":"Nicaise Ndembi, Bethanie Rammer, Joseph Fokam, Uttam Dinodia, Sofonias K Tessema, Jean Philbert Nsengimana, Sarah Mwangi, Edem Adzogenu, Landry Tsague Dongmo, Bleddyn Rees, Brian O'Connor, Trevor A Crowell, Wilmot James, Vittorio Colizzi, Ngashi Ngongo, Jean Kaseya","doi":"10.4102/jphia.v16i1.876","DOIUrl":"10.4102/jphia.v16i1.876","url":null,"abstract":"","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"16 1","pages":"876"},"PeriodicalIF":0.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miriam Nanyunja, Viviane Fossouo, Ebenezer Obi Daniel, Joseph C Okeibunor, Samuel Boland, Hilary K Njenge, Brice W Bicaba, Otim P C Ramadan, Solomon F Woldetsadik, Dick D Chamla, Fiona Braka, Abdou S Gueye
{"title":"Ensuring the continuity of essential health services during mpox response in the African region.","authors":"Miriam Nanyunja, Viviane Fossouo, Ebenezer Obi Daniel, Joseph C Okeibunor, Samuel Boland, Hilary K Njenge, Brice W Bicaba, Otim P C Ramadan, Solomon F Woldetsadik, Dick D Chamla, Fiona Braka, Abdou S Gueye","doi":"10.4102/jphia.v16i1.1227","DOIUrl":"10.4102/jphia.v16i1.1227","url":null,"abstract":"","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"16 1","pages":"1227"},"PeriodicalIF":0.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perspectives of parents and adolescents on sexual and reproductive health information communication in Ghana.","authors":"Frank B Agyei, Doreen K Kaura, Janet D Bell","doi":"10.4102/jphia.v16i1.845","DOIUrl":"10.4102/jphia.v16i1.845","url":null,"abstract":"<p><strong>Background: </strong>Parent-adolescent sexual and reproductive health (SRH) information communication is known to be associated with positive SRH outcomes of adolescents. This determinant of positive SRH outcomes of adolescents is therefore receiving attention in research in the African region.</p><p><strong>Aim: </strong>This study therefore explored and integrated the perspectives of parents and adolescents on SRH information communication in Ghana.</p><p><strong>Setting: </strong>The study was conducted at the Asante Akyem North Municipality of Ghana.</p><p><strong>Methods: </strong>A qualitative descriptive design was used to interview 10 parent-adolescent dyad. Participants were purposively recruited from the Asante Akyem North Municipality in Ghana. Thematic analysis was done inductively using Braun and Clarke's approach. ATLAS.ti version 23.0.7 was used to store and manage data.</p><p><strong>Results: </strong>Three themes emerged, namely, SRH information communicated by parents and their adolescents, motivation for communicating SRH information, and SRH information communication skills. Some form of SRH information communication take place between parents and adolescents although they lack the requisite skills to communicate such information.</p><p><strong>Conclusion: </strong>An SRH information communication intervention, which is culturally appropriate, is needed to train both parents and adolescents to communicate SRH information in Ghana.</p><p><strong>Contribution: </strong>The study contributes to the understanding of SRH information communication by highlighting the influence of cultural norms, social support and parental engagement on adolescents' access to accurate information, which can inform the development of culturally sensitive interventions to enhance SRH communication between parents and adolescents.</p>","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"16 1","pages":"845"},"PeriodicalIF":0.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epidemiological and anatomopathological profile of colorectal cancer: A cross-sectional study.","authors":"Lahoucine Amsdar, Jamal Tikouk, Mohamed Amine Baba, Hafid Arzoug, Jaouad Elkhalladi, Salima Zerouali, Kenza Oqbani, Ghizlane Rais, Mehdi Soufi","doi":"10.4102/jphia.v16i1.856","DOIUrl":"10.4102/jphia.v16i1.856","url":null,"abstract":"<p><strong>Background: </strong>Colorectal cancer (CRC) remains one of the leading causes of cancer-related deaths globally, with incidence and mortality rates exhibiting geographical disparities.</p><p><strong>Aim: </strong>This study aims to outline the pathological profile of CRC.</p><p><strong>Setting: </strong>The study was conducted in the anatomopathological laboratories of the Souss Massa region (SMR) in Morocco.</p><p><strong>Methods: </strong>The study examined the epidemiological and anatomopathological profile of CRC among patients diagnosed. We reviewed 238 anatomopathological results during the study period. Fisher's exact test and analysis of variance were performed using Statistical Package for Social Sciences (SPSS) version 20.</p><p><strong>Results: </strong>Rectum and sigmoid colon were the most common sites for CRC (76.9%), with adenocarcinomas emerging as the predominant histological variant (93.3%). Most tumours were moderately differentiated (96.6%), with many (83.1%) in advanced stages (T3, T4). The presence of vascular embolism in 31.9% of patients indicates aggressive disease progression. Additionally, the study discerned a slight male dominance (52.9%) in the prevalence of CRC and an average age of 59 among patients. Notably, sex showed a significant association with the manifestation of CRC across various organs (<i>p</i> = 0.028), as did histological types across different organs (<i>p</i> = 0.010). Age-related analysis found older patients (over 50 years) with advanced-stage CRC more frequently.</p><p><strong>Conclusion: </strong>The histopathological features of these tumours are associated with an alarming delay in diagnosis and a significant presence of vascular embolism in patients.</p><p><strong>Contribution: </strong>Delay in diagnosis of CRC is significant in the SMR. There is an urgent need to strengthen screening strategies and examine social determinants of health for earlier diagnosis.</p>","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"16 1","pages":"856"},"PeriodicalIF":0.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Birungi Mutahunga, Nahabwe Haven, Orikushaba I Magezi, James Mubangizi, Yusufu Kuule, Peter R Scull, Frank M Frey
{"title":"<i>Streptococcus pneumoniae</i> carriage and antibiotic use in children in southwestern Uganda.","authors":"Birungi Mutahunga, Nahabwe Haven, Orikushaba I Magezi, James Mubangizi, Yusufu Kuule, Peter R Scull, Frank M Frey","doi":"10.4102/jphia.v16i1.880","DOIUrl":"10.4102/jphia.v16i1.880","url":null,"abstract":"<p><strong>Background: </strong>Acute respiratory infection is a significant health threat in children under the age of 5 years in Uganda and can be caused by <i>Streptococcus pneumoniae</i>.</p><p><strong>Aim: </strong>This study documents caretaker behaviour in seeking treatment for suspected acute respiratory infection in children and estimates the prevalence of <i>S. pneumoniae</i> in healthy and sick children.</p><p><strong>Setting: </strong>The study was carried out in the catchment region of Bwindi Community Hospital, encompassing the sub-counties of Kanyantorogo, Kayonza and Mpungu in rural southwestern Uganda.</p><p><strong>Methods: </strong>This cross-sectional study was conducted from January 2023 to August 2023. Caretakers answered questions about the child's illness, symptoms, sources of treatment and medicines administered. Nasopharyngeal swabs were collected from children and cultured to identify <i>S. pneumoniae</i> using standard microbiological methods. Analyses were conducted using SPSS and ArcPro GIS.</p><p><strong>Results: </strong>Roughly half of the 422 families sampled reported that the child was ill within the past 2 weeks, the vast majority with symptoms consistent with a possible acute respiratory infection. Most (80%) sought treatment outside the home at a private or public health facility or drug shop. Regardless of treatment source, antibiotics (primarily amoxicillin) were administered 56% of the time. The prevalence of <i>S. pneumoniae</i> was 34% and positively associated with household density, household size and the number of children in the household.</p><p><strong>Conclusion: </strong>This study documents a high carriage rate of <i>S. pneumoniae</i> in the region and documents a high rate of antibiotic use in the region.</p><p><strong>Contribution: </strong>This study provides evidence to support a wider assessment of <i>S. pneumoniae</i> carriage and the potential for antibiotic resistance.</p>","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"16 1","pages":"880"},"PeriodicalIF":0.6,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}