EURO Journal on Decision Processes最新文献_第3页

Proposing a bi-objective model for the problem of designing a resilient supply chain network of pharmaceutical-health relief items under disruption conditions by considering lateral transshipment 通过考虑横向转运，提出了一种双目标模型，用于在中断条件下设计具有弹性的医药卫生救济物品供应链网络

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EURO Journal on Decision Processes Pub Date : 2023-01-01 DOI: 10.1016/j.ejdp.2023.100037

Soheil Javaheri Fazel , Mohammad Rostamkhani , Mehdi Rashidnejad

{"title":"Proposing a bi-objective model for the problem of designing a resilient supply chain network of pharmaceutical-health relief items under disruption conditions by considering lateral transshipment","authors":"Soheil Javaheri Fazel , Mohammad Rostamkhani , Mehdi Rashidnejad","doi":"10.1016/j.ejdp.2023.100037","DOIUrl":"10.1016/j.ejdp.2023.100037","url":null,"abstract":"<div><p>In this paper, a bi-objective mathematical model is presented for the problem of designing a resilient supply chain network of pharmaceutical-health relief items in the condition of disruption, taking into account the possibility of lateral transshipment. The first objective function of the model aims to minimize the total costs and considering the importance of effective and efficient distribution to meet the demand of patients in a humanitarian supply chain network, the second objective function is minimizing the total time required to deliver relief items to the demand points. Given the inherent uncertainty associated with the occurrence of a crisis and its impact on the supply chain network, a scenario-based robust optimization method is used to address the problem. The model is solved using the epsilon constraint method for small sizes and the NSGA-II meta-heuristic algorithm for larger sizes. In addition, the model is solved with and without lateral transshipment, and the results are compared and analyzed. The findings indicate that lateral transshipment can improve the performance of the supply chain and reduce the level of shortage.</p></div>","PeriodicalId":44104,"journal":{"name":"EURO Journal on Decision Processes","volume":"11 ","pages":"Article 100037"},"PeriodicalIF":1.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46271497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fairness and explainability in automatic decision-making systems. A challenge for computer science and law 自动决策系统中的公平性和可解释性。计算机科学和法律面临的挑战

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EURO Journal on Decision Processes Pub Date : 2023-01-01 DOI: 10.1016/j.ejdp.2023.100036

Th. Kirat , O. Tambou , V. Do , A. Tsoukiàs

{"title":"Fairness and explainability in automatic decision-making systems. A challenge for computer science and law","authors":"Th. Kirat , O. Tambou , V. Do , A. Tsoukiàs","doi":"10.1016/j.ejdp.2023.100036","DOIUrl":"https://doi.org/10.1016/j.ejdp.2023.100036","url":null,"abstract":"<div><p>The paper offers a contribution to the interdisciplinary constructs of analyzing fairness issues in automatic algorithmic decisions. <span>Section 2</span> shows that technical choices in supervised learning have social implications that need to be considered. <span>Section 3</span> proposes a contextual approach to the issue of unintended group discrimination, i.e. decision rules that are facially neutral but generate disproportionate impacts across social groups (e.g., gender, race or ethnicity). The contextualization will focus on the legal systems of the United States on the one hand and Europe on the other. In particular, legislation and case law tend to promote different standards of fairness on both sides of the Atlantic. Section 4 is devoted to the explainability of algorithmic decisions; it will confront and attempt to cross-reference legal concepts (in European and French law) with technical concepts and will highlight the plurality, even polysemy, of European and French legal texts relating to the explicability of algorithmic decisions. The conclusion proposes directions for further research.</p></div>","PeriodicalId":44104,"journal":{"name":"EURO Journal on Decision Processes","volume":"11 ","pages":"Article 100036"},"PeriodicalIF":1.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50203165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multi-period fuzzy portfolio optimization model subject to real constraints 真实约束下的多周期模糊投资组合优化模型

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EURO Journal on Decision Processes Pub Date : 2023-01-01 DOI: 10.1016/j.ejdp.2023.100041

Moad El Kharrim

引用次数: 0

A simple declarative model of the Federal Disaster Assistance Policy - modelling and measuring transparency 一个简单的联邦灾难援助政策的声明模型-建模和衡量透明度

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EURO Journal on Decision Processes Pub Date : 2023-01-01 DOI: 10.1016/j.ejdp.2023.100035

Mark Dukes

引用次数: 2

Multi-objective optimization in real-time operation of rainwater harvesting systems 雨水收集系统实时运行的多目标优化

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EURO Journal on Decision Processes Pub Date : 2023-01-01 DOI: 10.1016/j.ejdp.2023.100039

Yi Zhen , Kate Smith-Miles , Tim D. Fletcher , Matthew J. Burns , Rhys A. Coleman

引用次数: 0

Confidence in bargaining processes and outcomes: Empirical tests of a conceptual model 议价过程和结果中的信心:一个概念模型的实证检验

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EURO Journal on Decision Processes Pub Date : 2023-01-01 DOI: 10.1016/j.ejdp.2023.100028

Rudolf Vetschera , Luis C. Dias

引用次数: 0

Is there an ethical operational research practice? And what this implies for our research? 是否有合乎道德的运筹学实践？这对我们的研究意味着什么？

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EURO Journal on Decision Processes Pub Date : 2023-01-01 DOI: 10.1016/j.ejdp.2023.100029

O. Bellenguez , N. Brauner , A. Tsoukiàs

引用次数: 1

Determining the right time to advertise adopter numbers for a two-sided digital platform: An agent-based simulation optimization approach 确定公布双边数字平台采用者编号的正确时间：一种基于代理的模拟优化方法

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EURO Journal on Decision Processes Pub Date : 2023-01-01 DOI: 10.1016/j.ejdp.2023.100032

Michelle D. Haurand, Christian Stummer

{"title":"Determining the right time to advertise adopter numbers for a two-sided digital platform: An agent-based simulation optimization approach","authors":"Michelle D. Haurand, Christian Stummer","doi":"10.1016/j.ejdp.2023.100032","DOIUrl":"10.1016/j.ejdp.2023.100032","url":null,"abstract":"<div><p>The adoption of two-sided digital platforms is influenced by cross-side network effects, that is, the number of adopters on the demand side of a platform affects the number of adopters on the supply side and vice versa. Accordingly, publicizing adopter numbers might stimulate platform success. However, finding the right point in time to do so is difficult because there is little or no research on corresponding strategies and best practices based on already successful platforms are inconclusive. This paper addresses this research gap by (i) demonstrating the impact of publicizing adopter numbers on platform growth, (ii) analyzing the effect of market characteristics on the strategic fit of such information-sharing strategies, (iii) introducing an agent-based simulation optimization tool that aims to identify the optimal number of adopters on the other side of the platform that should be reached before advertising information is begun, and (iv) illustrating the applicability of such a tool by means of a real-world use case. Agent-based modeling and simulation was chosen because the effectiveness of advertising adopter numbers depends on various interactions between (potential) platform users, which gives rise to a complex system that cannot be properly captured via traditional analytical approaches. The simulation accounts for the stakeholders’ decision processes and can support the platform operator's decision on when to start publicizing adopter numbers. The results of our numerical experiments indicate that there is no single conclusive answer to the question when advertising adopter numbers should begin, as the right time depends on the specific market characteristics.</p></div>","PeriodicalId":44104,"journal":{"name":"EURO Journal on Decision Processes","volume":"11 ","pages":"Article 100032"},"PeriodicalIF":1.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44900255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resveratrol Inhibits High Glucose-Induced H9c2 Cardiomyocyte Hypertrophy and Damage via RAGE-Dependent Inhibition of the NF-κB and TGF-β1/Smad3 Pathways. 白藜芦醇通过 RAGE 依赖性抑制 NF-κB 和 TGF-β1/Smad3 通路抑制高血糖诱导的 H9c2 心肌细胞肥大和损伤

EURO Journal on Decision Processes Pub Date : 2022-02-25 eCollection Date: 2022-01-01 DOI: 10.1155/2022/7781910

Yanzhou Zhu, Fuling Wu, Qin Yang, Haixing Feng, Dingli Xu

{"title":"Resveratrol Inhibits High Glucose-Induced H9c2 Cardiomyocyte Hypertrophy and Damage via RAGE-Dependent Inhibition of the NF-<i>κ</i>B and TGF-<i>β</i>1/Smad3 Pathways.","authors":"Yanzhou Zhu, Fuling Wu, Qin Yang, Haixing Feng, Dingli Xu","doi":"10.1155/2022/7781910","DOIUrl":"10.1155/2022/7781910","url":null,"abstract":"<p><p>Hyperglycaemia is associated with the development of cardiac vascular disease. Resveratrol (RES) is a naturally occurring polyphenolic compound that possesses many biological properties, including anti-inflammatory properties and antioxidation functions. Our study aimed to explore the RES's protective roles on high glucose (HG)-induced H9c2 cells and the underlying mechanisms. Small-molecule inhibitors, western blotting (WB), as well as reverse-transcription PCR (RT-PCR) were employed to investigate the mechanisms underlying HG-induced damage in H9c2 cells. RES (40 <i>μ</i>g/mL) treatment significantly alleviated HG-induced cardiac hypertrophy and cardiac dysfunction. RES abated the HG-induced increase in the levels of extracellular matrix (ECM) components and inflammatory cytokines, reducing ECM accumulation and inflammatory responses. Additionally, RES administration prevented HG-induced mitochondrion-mediated cardiac apoptosis of myocardial cells. In terms of mechanisms, we demonstrated that RES ameliorated the HG-induced overexpression of receptor for advanced glycation endproducts (RAGE) and downregulation of NF-<i>κ</i>B signalling. Moreover, RES inhibited HG-induced cardiac fibrosis by inhibiting transforming growth factor beta 1 (TGF-<i>β</i>1)/Smad3-mediated ECM synthesis in cultured H9c2 cardiomyocytes. Further studies revealed that the effects of RES against HG-induced upregulation of NF-<i>κ</i>B and TGF-<i>β</i>1/Smad3 pathways were similar to those of FPS-ZM1, a RAGE inhibitor. Collectively, the results implied that RES might help alleviate HG-induced cardiotoxicity via RAGE-dependent downregulation of the NF-<i>κ</i>B and TGF-<i>β</i>/Smad3 pathways. This study provided evidence that RES can be developed as a promising cardioprotective drug.</p>","PeriodicalId":44104,"journal":{"name":"EURO Journal on Decision Processes","volume":"3 1","pages":"7781910"},"PeriodicalIF":0.0,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74384178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

C-KE/I: A pragmatic framework for policy innovation C-KE/I:务实的政策创新框架

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EURO Journal on Decision Processes Pub Date : 2022-01-01 DOI: 10.1016/j.ejdp.2022.100016

Yves Meinard , Irene Pluchinotta

{"title":"C-KE/I: A pragmatic framework for policy innovation","authors":"Yves Meinard , Irene Pluchinotta","doi":"10.1016/j.ejdp.2022.100016","DOIUrl":"10.1016/j.ejdp.2022.100016","url":null,"abstract":"<div><p>Improving policy making is key to address numerous contemporary challenges such as the environmental crisis, climate change, global inequality, financial crises, or pandemics. Policy making is a sequence of stages structuring policy problems and choices made to address them. Among these stages, policy design is a crucial phase since it impacts the quality of the policy alternatives being considered. Policy design is, however, largely neglected in the scientific literature, and in practice it is mainly conducted informally. Design theory, and more specifically Concept-Knowledge (C-K) theory, originally aimed at assisting the process of creating marketable objects, offers promises to formalize and rationalize policy design. We critically analyze this theory, showing that, despite its strengths, as it stands it is ill-adapted to support the innovative design of policy alternatives. For that purpose, we propose a framework, C-K<sup>E/I</sup>. This framework, which is inspired by and compatible with C-K, appraises innovation based on the explicit or implicit modal statements held by a certain individual or group (“E/I” stands for Explicit vs. Implicit). Through an ex-post analysis of a case study—the search for innovative policy solutions to water management problems in the Apulia Region, Italy—we illustrate the practical applicability and usefulness of our framework.</p></div>","PeriodicalId":44104,"journal":{"name":"EURO Journal on Decision Processes","volume":"10 ","pages":"Article 100016"},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S219394382200005X/pdfft?md5=c7a7e309bc761c1bbae4e68ddc4c7193&pid=1-s2.0-S219394382200005X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44862767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0