Tetrahedron Letters最新文献_第9页

Asymmetric Diels–Alder reaction of heterocyclic o-quinodimethane with 2-arylidene-1,3-indanedoines to access tetrahydrospirocarbazole-indanediones via trienamine intermediate 杂环邻喹啉二甲烷与2-芳基烷-1,3-茚二酮经三胺中间体合成四氢螺咔唑-茚二酮的不对称Diels-Alder反应

IF 1.5 4区化学

Tetrahedron Letters Pub Date : 2025-01-30 DOI: 10.1016/j.tetlet.2024.155428

Raghupathi Mutyala , K. Rajitha , Jagadeesh Babu Nanubolu , Rajesh Chandra

引用次数: 0

Formation of triarylphosphines via PH/CF cross coupling reactions catalyzed by nickel 镍催化PH/CF交叉偶联反应生成三芳基膦

IF 1.5 4区化学

Tetrahedron Letters Pub Date : 2025-01-30 DOI: 10.1016/j.tetlet.2024.155445

Meng-Ting Xiang , Lei Fan , Qian Xu , Li Zhang , Shuai Wang , Hong Zhong , Jia Yang

引用次数: 0

Recent advances in the electrophilic halogenation of aromatic compounds using N-halosuccinimides (NXS) n -卤代琥珀酰亚胺（NXS）在芳香化合物亲电卤化反应中的研究进展

IF 1.5 4区化学

Tetrahedron Letters Pub Date : 2025-01-30 DOI: 10.1016/j.tetlet.2024.155419

Kiyoshi Tanemura

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Recent advances in development of bibenzo[c]thiophene derivatives for application in functional materials 二苯并[c]噻吩衍生物在功能材料中的应用研究进展

IF 1.5 4区化学

Tetrahedron Letters Pub Date : 2025-01-30 DOI: 10.1016/j.tetlet.2024.155393

Yousuke Ooyama, Keiichi Imato

{"title":"Recent advances in development of bibenzo[c]thiophene derivatives for application in functional materials","authors":"Yousuke Ooyama, Keiichi Imato","doi":"10.1016/j.tetlet.2024.155393","DOIUrl":"10.1016/j.tetlet.2024.155393","url":null,"abstract":"<div><div>1,1′- and 4,4′-bibenzo[<em>c</em>]thiophenes as the 1,1′-dimer and 4,4′-dimer of benzo[<em>c</em>]thiophene, respectively, have gained more and more attention in recent years because of pioneering challenge to the development of facile and efficient synthetic method and their attractive photophysical and electrochemical properties to be a promising fluorophore and photosensitizer for highly efficient bioimaging, phototheranostics, and optoelectronic devices. Thus, this review is focused on development of bibenzo[<em>c</em>]thiophene derivatives and their potential as a π-building block for creating new functional materials. First, synthetic methods for 1,1′- and 4,4′-bibenzo[<em>c</em>]thiophene derivatives, and their photophysical and electrochemical properties such as photoabsroption, fluorescence, and redox properties and HOMO and LUMO energy levels are discussed. Moreover, we present not only a practical application of bibenzo[<em>c</em>]thiophene unit to optoelectronic devices and fluorescence bioimaging and phototherapy bust also creation of a new-type functional dye material composed of bibenzo[<em>c</em>]thiophene skeleton.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"155 ","pages":"Article 155393"},"PeriodicalIF":1.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143159526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Iron-catalyzed one-pot tandem oxidation/acylation/dearomatization of biaryl ynones with benzyl alcohols: access to diversified acylated spiro[5.5]trienones 铁催化双芳酮与苯甲醇的一锅串联氧化/酰化/脱芳化：获得多种酰化螺[5.5]三烯酮

IF 1.5 4区化学

Tetrahedron Letters Pub Date : 2025-01-30 DOI: 10.1016/j.tetlet.2025.155469

Dong Xia , Yanfeng Miao , Hongjian Ji , Wenchao Yang , Yun Shi

引用次数: 0

Convenient synthesis of highly functionalized isoxazoles including an amidine skeleton based on trichloroacetamidine, alkynes, and hydroxyimidoyl chloride 以三氯乙脒、炔烃和羟基酰氯为基础的高功能化异恶唑的便捷合成

IF 1.5 4区化学

Tetrahedron Letters Pub Date : 2025-01-30 DOI: 10.1016/j.tetlet.2024.155443

Manijeh Nematpour

引用次数: 0

Enzymatic synthesis and characterization of nicotinamide riboside pseudouridine diphosphate 烟酰胺核苷假尿苷二磷酸的酶合成与表征

IF 1.5 4区化学

Tetrahedron Letters Pub Date : 2025-01-30 DOI: 10.1016/j.tetlet.2024.155432

Yinghan Hu , Xueying Wang , Yanzhe Huang , Xiaojia Guo , Haizhao Xue , Martin Pfeiffer , Bernd Nidetzky , Zongbao K. Zhao

引用次数: 0

Regioselective synthesis of quaternized cellulose nanocrystals and its antibacterial properties in clinical isolates of methicillin-resistant Staphylococcus aureus 季铵化纤维素纳米晶的区域选择性合成及其对耐甲氧西林金黄色葡萄球菌临床分离株的抗菌性能

IF 1.5 4区化学

Tetrahedron Letters Pub Date : 2025-01-30 DOI: 10.1016/j.tetlet.2024.155420

Nadarajah Vasanthan, Dong Kwon, Steven Furman

{"title":"Regioselective synthesis of quaternized cellulose nanocrystals and its antibacterial properties in clinical isolates of methicillin-resistant Staphylococcus aureus","authors":"Nadarajah Vasanthan, Dong Kwon, Steven Furman","doi":"10.1016/j.tetlet.2024.155420","DOIUrl":"10.1016/j.tetlet.2024.155420","url":null,"abstract":"<div><div>Quaternized cellulose nanocrystals (CNCs) were prepared by chloroacetylation and subsequent reaction with tertiary amines. The chloroacetylation of CNCs and quaternary ammonium-modified CNCs were characterized by the analysis of FTIR and solid-state NMR spectroscopies. Chloroacetylation of CNCs was found to be highly regioselective. CNCs can be chemically modified to tailor their properties to improve dispersion in the polymer matrix, which expands the application of CNCs as reinforcing materials. Biological evaluation of the ammonium-modified compounds was conducted using the disc diffusion test, minimum bactericidal concentration, and bacterial killing pattern for methicillin-associated multidrug-resistant clinical isolates of <em>Staphylococcus aureus</em>, one of the most problematic bacterial human pathogens. Results showed that the CNC with alkyl chains with 16 carbons had more antibacterial properties than that of 10 carbons against all tested clinical isolates of <em>Staphylococcus aureus</em> regardless of antibiotic resistance or sensitivity. This finding suggests that the ammonium-modified CNCs may be applicable to treat <em>Staphylococcus aureus</em> infections.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"155 ","pages":"Article 155420"},"PeriodicalIF":1.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143159579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Asymmetric one-pot synthesis of trans-stilbene oxide via desymmetrizing monosulfonylation of meso-hydrobenzoin catalyzed by a chiral bisoxazoline–copper (II) complex 手性双恶唑-铜（II）配合物催化中羟基苯甲酸反对称单磺化一锅法合成反式二苯乙烯氧化物

IF 1.5 4区化学

Tetrahedron Letters Pub Date : 2025-01-30 DOI: 10.1016/j.tetlet.2024.155435

Kenji Yatsuzuka, Midori Kawasaki, Ryuichi Shirai

引用次数: 0

Unified synthesis of DSPC and PSPC: Chemical entities of hydrogenated soy L-α-phosphatidylcholine (HSPC), a key component of liposomal drug formulations DSPC和PSPC的统一合成：氢化大豆L-α-磷脂酰胆碱（HSPC）的化学实体，是脂质体药物制剂的关键成分

IF 1.5 4区化学

Tetrahedron Letters Pub Date : 2025-01-30 DOI: 10.1016/j.tetlet.2024.155424

Pallavi Rao, Madhavachary Rudrakshula, Rajendar Potham, Rahul Varma Katari, Vishnuvardhana Vema Reddy Eda, Saikat Sen, Srinivas Oruganti

{"title":"Unified synthesis of DSPC and PSPC: Chemical entities of hydrogenated soy L-α-phosphatidylcholine (HSPC), a key component of liposomal drug formulations","authors":"Pallavi Rao, Madhavachary Rudrakshula, Rajendar Potham, Rahul Varma Katari, Vishnuvardhana Vema Reddy Eda, Saikat Sen, Srinivas Oruganti","doi":"10.1016/j.tetlet.2024.155424","DOIUrl":"10.1016/j.tetlet.2024.155424","url":null,"abstract":"<div><div>A simple, unified and scalable strategy, emanating from the readily available chiral pool <span>d</span>-solketal, has been employed to obtain the enantiomerically pure components of hydrogenated soy L-α-phosphatidylcholine (HSPC), namely distearoyl phosphatidylcholine (DSPC) and 1-palmitoyl-2-stearoyl-phosphatidylcholine (PSPC). HSPC is obtained by hydrogenating naturally occurring soy L-α-lecithin; this affords a glycerophospholipid mixture containing C-16 (minor) or C-18 (major) fatty acid chain at <em>sn</em>-1, C-18 chain at <em>sn</em>-2 position and phosphatidylcholine at <em>sn</em>-3 position. HSPC already has numerous applications as an excipient and essential component in many FDA approved liposomal drug formulations such as Doxil® (doxorubicin HCl liposome injection) and AmBisome® (amphotericin B liposome injection). However, there is increasing interest in uncovering the potential individual applications of its components, DSPC and PSPC, too. In this context, the current synthesis offers a strategy to have a ready bespoke access to multi-gram quantities of DSPC and PSPC (in particular) that does not rely on tedious separation of the components of HSPC.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"155 ","pages":"Article 155424"},"PeriodicalIF":1.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143159666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0