CAHIERS DE NUTRITION ET DE DIETETIQUE最新文献

{"title":"Association between the A49P polymorphism (TAS2R38) and chili consumption in Mexican adult population","authors":"Alma Daniela Olvera Martínez, Genaro Rodriguez-Uribe, José de Jesús Manríquez Torres, Dr Omar Ramos-Lopez","doi":"10.1016/j.cnd.2026.08.066","DOIUrl":"10.1016/j.cnd.2026.08.066","url":null,"abstract":"<div><h3>Background/objective</h3><div>Chili is a distinctive component of Mexican culture and diet since pre-Hispanic times. However, the effect of chili and other foods on health may vary according to individual tolerance, influenced by various factors, including genetics. The aim of this study was to evaluate the association between the A49P polymorphism of the <em>TAS2R38</em> gene and chili consumption in Mexican adults.</div></div><div>Chili is a distinctive component of Mexican culture and diet since pre-Hispanic times. However, the effect of chili and other foods on health may vary according to individual tolerance, influenced by various factors, including genetics. The aim of this study was to evaluate the association between the A49P polymorphism of the <em>TAS2R38</em> gene and chili consumption in Mexican adults.</div><div><h3>Methods</h3><div>A cross-sectional analytical study was conducted with 200 adults of both sexes, residents of Tijuana, Baja California, Mexico. A validated questionnaire was applied to assess chili consumption. Genotyping of the A49P polymorphism (TAS2R38) was performed using an allelic discrimination assay. Chi<sup>2</sup> tests and logistic regression were used.</div></div><div>A cross-sectional analytical study was conducted with 200 adults of both sexes, residents of Tijuana, Baja California, Mexico. A validated questionnaire was applied to assess chili consumption. Genotyping of the A49P polymorphism (TAS2R38) was performed using an allelic discrimination assay. Chi<sup>2</sup> tests and logistic regression were used.</div><div><h3>Results</h3><div>The frequency of allele A was 52.25% and allele P was 47.75%. A total of 10% individuals had genotype AA, 84.5% had AP, and 5.5% had PP. The 100% of individuals with genotype AA consumed chili, showing a statistically significant association (<em>P</em> <!-->=<!--> <!-->0.024). Code ethic (D235, accepted on 22 October 2019).</div></div><div>The frequency of allele A was 52.25% and allele P was 47.75%. A total of 10% individuals had genotype AA, 84.5% had AP, and 5.5% had PP. The 100% of individuals with genotype AA consumed chili, showing a statistically significant association (<em>P</em> <!-->=<!--> <!-->0.024). Code ethic (D235, accepted on 22 October 2019).</div><div><h3>Conclusions</h3><div>The results show that chili consumption in the Mexican population is significantly associated with the A49P polymorphism of the <em>TAS2R38</em> gene, reflecting the genetic influence on preference for spicy foods. This finding supports the use of genetic profiling as a tool for designing personalized nutrition strategies to improve dietary adherence, promote health, and contribute to the future prevention of diet-related diseases.</div></div><div>The results show that chili consumption in the Mexican population is significantly associated with the A49P polymorphism of the <em>TAS2R38</em> gene, reflecting the genetic influence on preference for spicy foods. This finding ","PeriodicalId":43722,"journal":{"name":"CAHIERS DE NUTRITION ET DE DIETETIQUE","volume":"61 ","pages":"Pages e36-e37"},"PeriodicalIF":0.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of omega-3 supplementation on telomere length, inflammation, and oxidative stress in women with systemic lupus erythematosus: Protocol for a randomized double-blind placebo-controlled trial","authors":"Beatriz G. Carvalho, Eduardo F. Borba, Marcelo M. Rogero, Carolina F. Nicoletti","doi":"10.1016/j.cnd.2026.08.072","DOIUrl":"10.1016/j.cnd.2026.08.072","url":null,"abstract":"<div><h3>Background</h3><div>Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by persistent inflammation, oxidative stress, immune dysregulation, and accelerated cellular aging. Telomere shortening has been associated with disease progression and immunosenescence in SLE. Omega-3 polyunsaturated fatty acids (PUFAs), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), may exert anti-inflammatory and antioxidant effects; however, their impact on telomere biology in women with SLE remains unclear.</div></div><div>Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by persistent inflammation, oxidative stress, immune dysregulation, and accelerated cellular aging. Telomere shortening has been associated with disease progression and immunosenescence in SLE. Omega-3 polyunsaturated fatty acids (PUFAs), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), may exert anti-inflammatory and antioxidant effects; however, their impact on telomere biology in women with SLE remains unclear.</div><div><h3>Objective</h3><div>To evaluate the effects of omega-3 supplementation on leukocyte telomere length, inflammatory pathways, and oxidative stress biomarkers in women with SLE in remission.</div></div><div>To evaluate the effects of omega-3 supplementation on leukocyte telomere length, inflammatory pathways, and oxidative stress biomarkers in women with SLE in remission.</div><div><h3>Methods</h3><div>This study is a randomized, double-blind, placebo-controlled, parallel-group clinical trial involving women aged 18–45 years with SLE in remission and healthy controls. Participants will be randomized (1:1) to receive either omega-3 supplementation (3,600<!--> <!-->mg/day EPA<!--> <!-->+<!--> <!-->DHA) or placebo for 12 weeks. The primary outcome is relative leukocyte telomere length, assessed by quantitative PCR using the telomere-to-single-copy gene (T/S) ratio. Secondary outcomes include inflammatory signaling pathways in peripheral blood mononuclear cells, oxidative stress biomarkers, antioxidant capacity, disease activity, anthropometric parameters, dietary intake, and physical activity. Outcomes will be assessed at baseline and after the intervention. The study was approved by the local Ethics Committee (CAAE: 92044025.6.0000.0068) and registered at ClinicalTrials.gov (<span><span>NCT07393399</span><svg><path></path></svg></span>).</div></div><div>This study is a randomized, double-blind, placebo-controlled, parallel-group clinical trial involving women aged 18–45 years with SLE in remission and healthy controls. Participants will be randomized (1:1) to receive either omega-3 supplementation (3,600<!--> <!-->mg/day EPA<!--> <!-->+<!--> <!-->DHA) or placebo for 12 weeks. The primary outcome is relative leukocyte telomere length, assessed by quantitative PCR using the telomere-to-single-copy gene (T/S) ratio. Secondary outcomes include inflammatory signaling pathwa","PeriodicalId":43722,"journal":{"name":"CAHIERS DE NUTRITION ET DE DIETETIQUE","volume":"61 ","pages":"Pages e39-e40"},"PeriodicalIF":0.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flaxseed oil intake enhances exercise-induced adult hippocampal neurogenesis in a diet-induced obese mouse model","authors":"Leandro Kansuke Oharomari, Camila Venturini Ayres Cunha, Letícia Maria Paula da Silva, Thaiane da Silva Riosa, Talitha Silva Meneguelli, Danillo Henrique Travensolo Buoro, Maria Luiza Salmazo Gatz, José Rodrigo Pauli, Eduardo Rochete Ropelle, Adelino Sanchez Ramos da Silva, Dennys Esper Cintra","doi":"10.1016/j.cnd.2026.08.067","DOIUrl":"10.1016/j.cnd.2026.08.067","url":null,"abstract":"<div><h3>Background</h3><div>Adult hippocampal neurogenesis (AHN, a process in which newborn neurons are generated in the subgranular zone of the dentate gyrus) has been linked to memory, learning, and mood. Its disruption has also been linked with cognitive decline and anxiety symptoms. In addition, an emerging literature has shown that obesity may impair AHN. On the other hand, exercise and nutrition play an important role in AHN homeostasis.</div></div><div>Adult hippocampal neurogenesis (AHN, a process in which newborn neurons are generated in the subgranular zone of the dentate gyrus) has been linked to memory, learning, and mood. Its disruption has also been linked with cognitive decline and anxiety symptoms. In addition, an emerging literature has shown that obesity may impair AHN. On the other hand, exercise and nutrition play an important role in AHN homeostasis.</div><div><h3>Objective</h3><div>Evaluate whether the combined effects of flaxseed oil (a plant-based omega3 source) intake and exercise training can ameliorate AHN in a high-fat diet-induced obese mouse model (HFD).</div></div><div>Evaluate whether the combined effects of flaxseed oil (a plant-based omega3 source) intake and exercise training can ameliorate AHN in a high-fat diet-induced obese mouse model (HFD).</div><div><h3>Methods</h3><div>Four-week-old, male, Swiss mice were fed with standard chow or a high-fat diet (35% w/w fat). After eight weeks, mice in the HFD were separated into four groups: HF group, FS group (10% of lard substituted by flaxseed oil), EX group (treadmill running, 5<!--> <!-->×<!--> <!-->week, 50<!--> <!-->min, 60% V peak), and ExFs (flaxseed oil intake<!--> <!-->+<!--> <!-->exercise training). After 4 weeks of treatment, mice underwent behavioral tests, and samples were collected for analysis of neurogenesis markers and neurotrophic signaling. All experimental procedures were approved by the local animal ethics committee (protocol 6230–1/2023).</div></div><div>Four-week-old, male, Swiss mice were fed with standard chow or a high-fat diet (35% w/w fat). After eight weeks, mice in the HFD were separated into four groups: HF group, FS group (10% of lard substituted by flaxseed oil), EX group (treadmill running, 5<!--> <!-->×<!--> <!-->week, 50<!--> <!-->min, 60% V peak), and ExFs (flaxseed oil intake<!--> <!-->+<!--> <!-->exercise training). After 4 weeks of treatment, mice underwent behavioral tests, and samples were collected for analysis of neurogenesis markers and neurotrophic signaling. All experimental procedures were approved by the local animal ethics committee (protocol 6230–1/2023).</div><div><h3>Results</h3><div>The high-fat diet yields an obese phenotype followed by increased anxiety symptoms and decreased hippocampal brain-derived neurotrophic factor (BDNF). Exercise alone mitigated diet-induced anxiety behavior; however, only when combined with flaxseed oil intake did the number of positive cells marked with neurogenesis markers (e.g., dou","PeriodicalId":43722,"journal":{"name":"CAHIERS DE NUTRITION ET DE DIETETIQUE","volume":"61 ","pages":"Page e37"},"PeriodicalIF":0.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of metabolites with anti-inflammatory effects in Kefir: Potential applications for health","authors":"Maíza Santana Pedro, Ricardo Reis Rodrigues, Eduardo Nascimentos Barreto, Thiago Alves da Silva, Ana Clara Fernandes Peixoto, Julliane Dutra Medeiro, Poliana Guiomar de Almeida Brasiel, Sheila Cristina Potente Dutra Luquetti","doi":"10.1016/j.cnd.2026.08.043","DOIUrl":"10.1016/j.cnd.2026.08.043","url":null,"abstract":"<div><h3>Background/objective</h3><div>Kefir is a probiotic fermented milk composed of a complex microbiota, with several health benefits attributed to its intake. For commercial production, understanding the shifts in the metabolic profile and stability of the beverage during storage, thereby identifying the behavior of compounds potentially responsible for its beneficial effects. This work aims to compare the metabolic profile of fresh milk kefir and under refrigeration.</div></div><div>Kefir is a probiotic fermented milk composed of a complex microbiota, with several health benefits attributed to its intake. For commercial production, understanding the shifts in the metabolic profile and stability of the beverage during storage, thereby identifying the behavior of compounds potentially responsible for its beneficial effects. This work aims to compare the metabolic profile of fresh milk kefir and under refrigeration.</div><div><h3>Methods</h3><div>Kefir grains originated from Universidade Federal de Juiz de Fora, Minas Gerais, Brazil. Kefir was prepared using 10<!--> <!-->g of kefir grains and 100<!--> <!-->mL of whole pasteurized milk incubated at 25<!--> <!-->°C for 24<!--> <!-->hours. After grain removal, one sample was collected (K1) while another was refrigerated (2–5<!--> <!-->°C) for 7 days (K2). Ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was employed to perform the untargeted metabolomics (Thermo Vanquish™ UHPLC and Thermo Q Exactive™ HF-X). The Log2FC value was used to characterize the differential metabolites, indicating the greatest changes in relative abundance during storage.</div></div><div>Kefir grains originated from Universidade Federal de Juiz de Fora, Minas Gerais, Brazil. Kefir was prepared using 10<!--> <!-->g of kefir grains and 100<!--> <!-->mL of whole pasteurized milk incubated at 25<!--> <!-->°C for 24<!--> <!-->hours. After grain removal, one sample was collected (K1) while another was refrigerated (2–5<!--> <!-->°C) for 7 days (K2). Ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was employed to perform the untargeted metabolomics (Thermo Vanquish™ UHPLC and Thermo Q Exactive™ HF-X). The Log2FC value was used to characterize the differential metabolites, indicating the greatest changes in relative abundance during storage.</div><div><h3>Results</h3><div>Fold change<!--> <!-->≥<!--> <!-->2 or fold change<!--> <!-->≤<!--> <!-->0.5 were considered as significant and selected, resulting in 614 differential metabolites expressed. 1,2-Dilauroyl-sn-glycerol had the highest value (Log2FC<!--> <!-->=<!--> <!-->9.492), representing the most up-regulated differential metabolite. This compound is a diacylglycerol (DAG), which can act by activating protein kinase C. Saturated DAGs, such as 1,2-Dilauroyl-sn-glycerol, are used for triglyceride synthesis or as structural components. Conversely, unsaturated DAGs participate in cell signaling, like another metabolite fou","PeriodicalId":43722,"journal":{"name":"CAHIERS DE NUTRITION ET DE DIETETIQUE","volume":"61 ","pages":"Page e24"},"PeriodicalIF":0.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between the Brazilian Healthy Eating Index and its components, FTO polymorphisms and Body Mass Index in a cross-sectional population-based survey","authors":"Tatiane Mieko de Meneses Fujii, Marina Maintinguer Norde, Regina Mara Fisberg, Dirce Maria Lobo Marchioni, Marcelo Macedo Rogero","doi":"10.1016/j.cnd.2026.08.092","DOIUrl":"10.1016/j.cnd.2026.08.092","url":null,"abstract":"<div><h3>Objective</h3><div>We aimed to investigate the association of the Brazilian Healthy Eating Index Revised (BHEI-R), its components, and FTO genetic variants with obesity in a Brazilian cross-sectional population-based survey.</div></div><div>We aimed to investigate the association of the Brazilian Healthy Eating Index Revised (BHEI-R), its components, and FTO genetic variants with obesity in a Brazilian cross-sectional population-based survey.</div><div><h3>Methods</h3><div>A subsample of 244 adults (mean age 37.1 years) who participated in the Health Survey of São Paulo (HS-SP) 2008–2011, Brazil, was included in this study. Their socioeconomic, lifestyle, dietary, anthropometric, and genetic data were analyzed. The obesity genetic risk score (GRS) was composed of three <em>FTO</em> gene Genome-Wide Association Studies (GWAS)-identified single nucleotide polymorphisms (rs8050136; rs9930506; rs9939609). The BHEI-R and its components were calculated using data from two 24-hour dietary recalls (24hR). Ethical approval for this study (protocol number 2001) was granted by the Ethics Committee of the School of Public Health at the University of São Paulo, and all participants signed the informed consent form.</div></div><div>A subsample of 244 adults (mean age 37.1 years) who participated in the Health Survey of São Paulo (HS-SP) 2008–2011, Brazil, was included in this study. Their socioeconomic, lifestyle, dietary, anthropometric, and genetic data were analyzed. The obesity genetic risk score (GRS) was composed of three <em>FTO</em> gene Genome-Wide Association Studies (GWAS)-identified single nucleotide polymorphisms (rs8050136; rs9930506; rs9939609). The BHEI-R and its components were calculated using data from two 24-hour dietary recalls (24hR). Ethical approval for this study (protocol number 2001) was granted by the Ethics Committee of the School of Public Health at the University of São Paulo, and all participants signed the informed consent form.</div><div><h3>Results</h3><div>Body mass index (BMI) was inversely associated with the intake of total vegetables (β<!--> <!-->=<!--> <!-->−0.04; <em>P</em> <!-->=<!--> <!-->0.004) and of dark green and orange vegetables and legumes (β<!--> <!-->=<!--> <!-->−0.05; <em>P</em> <!-->=<!--> <!-->0.002) intake. Statistically significant interactions were found between the GRS and the intake of total grains (<em>P</em> <!-->=<!--> <!-->0.029), milk and dairy (<em>P</em> <!-->=<!--> <!-->0.054), and meat, eggs and beans (<em>P</em> <!-->=<!--> <!-->0.028). Additionally, the GRS interacted with carbohydrate-derived calorie intake (<em>P</em> <!-->=<!--> <!-->0.011) in influencing BMI. No statistically significant association was observed between the GRS and BMI.</div></div><div>Body mass index (BMI) was inversely associated with the intake of total vegetables (β<!--> <!-->=<!--> <!-->−0.04; <em>P</em> <!-->=<!--> <!-->0.004) and of dark green and orange vegetables and legumes (β<!--> <!-->=<!--> <!-->−","PeriodicalId":43722,"journal":{"name":"CAHIERS DE NUTRITION ET DE DIETETIQUE","volume":"61 ","pages":"Pages e49-e50"},"PeriodicalIF":0.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rethinking the recommended dietary allowances for essential fatty acids under the nutritional genomics dynamic perspective","authors":"Dennys Esper Cintra","doi":"10.1016/j.cnd.2026.08.022","DOIUrl":"10.1016/j.cnd.2026.08.022","url":null,"abstract":"<div><h3>Background/objective</h3><div>Current dietary recommendations for essential fatty acids are based on the premise that the endogenous conversion of short-chain omega-3 and omega-6 fatty acids into their biologically active long-chain derivatives is limited and relatively constant. This lecture discusses emerging evidence suggesting that the expression of fatty acid elongases and desaturases is dynamically regulated across tissues, potentially challenging current assumptions regarding essential fatty acid requirements.</div></div><div>Current dietary recommendations for essential fatty acids are based on the premise that the endogenous conversion of short-chain omega-3 and omega-6 fatty acids into their biologically active long-chain derivatives is limited and relatively constant. This lecture discusses emerging evidence suggesting that the expression of fatty acid elongases and desaturases is dynamically regulated across tissues, potentially challenging current assumptions regarding essential fatty acid requirements.</div><div><h3>Methods</h3><div>Male C57BL/6 mice received a single oral gavage of flaxseed oil (100<!--> <!-->μL), a dietary source of α-linolenic acid (ALA, omega-3). Tissues were collected immediately before administration (0<!--> <!-->h) or at 2, 4, 8, 16, and 24<!--> <!-->hours after gavage. A parallel control group received saline. Gene expression of the fatty acid desaturases (Fads1 and Fads2) and elongases (Elovl2 and Elovl5) was quantified by RT-qPCR in white adipose tissue, skeletal muscle, liver, testes, lungs, adrenal glands, skin, hypothalamus, hippocampus, and cerebellum. Fatty acid profiles were determined by gas chromatography and molecularly confirmed by mass spectrometry.</div></div><div>Male C57BL/6 mice received a single oral gavage of flaxseed oil (100<!--> <!-->μL), a dietary source of α-linolenic acid (ALA, omega-3). Tissues were collected immediately before administration (0<!--> <!-->h) or at 2, 4, 8, 16, and 24<!--> <!-->hours after gavage. A parallel control group received saline. Gene expression of the fatty acid desaturases (Fads1 and Fads2) and elongases (Elovl2 and Elovl5) was quantified by RT-qPCR in white adipose tissue, skeletal muscle, liver, testes, lungs, adrenal glands, skin, hypothalamus, hippocampus, and cerebellum. Fatty acid profiles were determined by gas chromatography and molecularly confirmed by mass spectrometry.</div><div><h3>Results</h3><div>Preliminary analyses confirmed the liver as a major site of omega-3 fatty acid bioconversion, consistent with current knowledge. However, evaluation of extrahepatic tissues revealed a more complex pattern. While some tissues exhibited minimal changes in long-chain fatty acid content following flaxseed oil administration, significant alterations were observed in the expression of Fads1, Fads2, Elovl2, and Elovl5. Importantly, these responses were both tissue-specific and time-dependent, suggesting differential regulation of fatty acid biosynt","PeriodicalId":43722,"journal":{"name":"CAHIERS DE NUTRITION ET DE DIETETIQUE","volume":"61 ","pages":"Page e13"},"PeriodicalIF":0.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Développer des recettes de viandes adaptées aux capacités de mastication et de salivation des personnes âgées : l’approche participative du projet ALIMADENT","authors":"Claire Sulmont-Rossé,&nbsp;Chantal Septier,&nbsp;Gilles Feron","doi":"10.1016/j.cnd.2025.12.002","DOIUrl":"10.1016/j.cnd.2025.12.002","url":null,"abstract":"<div><div>L’objectif de ce travail était de concevoir et valider des recettes de viande adaptées aux capacités de mastication et de salivation des personnes âgées. Ce travail s’est appuyé sur une approche participative inédite, impliquant les seniors à la fois dans le financement du projet et le développement des recettes. Il s’est articulé en 3 étapes : réalisation d’une enquête sur les habitudes d’achat et de préparation de la viande des seniors ; développement de recettes par deux chefs cuisiniers en utilisant des techniques permettant d’avoir une viande tendre et juteuse ; réalisation de tests à domicile auprès de deux panels de personnes âgées pour évaluer la faisabilité des recettes ainsi que l’appréciation et la texture des plats obtenus. Ceci a permis de finaliser un livret de recettes contenant 4 fiches techniques (choix des morceaux, découpe à contre-fibre, cuisson à basse température, cuisson dans un liquide) et 15 recettes : 3 recettes par mode de cuisson (sautée à la poêle, rôtie au four et mijotée en cocotte), 3 recettes de viande confite et 3 recettes à base de viande hachée. Ce livret constitue un outil concret pour soutenir la consommation de viande chez les personnes âgées, contribuant ainsi au maintien des apports protéiques et à la prévention de la dénutrition au sein de cette population.</div></div><div><div>The aim of this project was to design and validate meat recipes adapted to the chewing and salivary capacities of older people. It relied on a unique participatory approach, involving older people in both funding the project funding and developing the recipes. It consisted in 3 steps: a survey to investigate meat purchasing and preparation habits among older people; recipe development by two professional chefs using techniques designed to ensure tender and juicy meat; home testing with two panels of older people assessing the feasibility of the recipes as well as the acceptability and the texture of the dishes. This work led to the creation of a recipe booklet comprising four technical sheets (choice of cuts, slicing against the grain, low-temperature cooking, cooking in liquid) and 15 recipes: 3 for each cooking method (pan-fried, oven-roasted and pot-braised), 3 confit-style dishes, and three based on minced meat recipes. This booklet provides a practical tool to maintain meat consumption among the older people, thereby supporting adequate protein intake and prevent undernutrition in this population.</div></div>","PeriodicalId":43722,"journal":{"name":"CAHIERS DE NUTRITION ET DE DIETETIQUE","volume":"61 1","pages":"Pages 61-74"},"PeriodicalIF":0.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147636747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Le programme VIF : renouveler les interventions communautaires pour une meilleure efficacité","authors":"Sandrine Raffin ,&nbsp;Stéphane Sibalo ,&nbsp;Thibault Deschamps ,&nbsp;Patricia Gurviez","doi":"10.1016/j.cnd.2025.11.004","DOIUrl":"10.1016/j.cnd.2025.11.004","url":null,"abstract":"<div><div>L’obésité infantile est un problème de santé publique majeure. L’inactivité physique, les comportements sédentaires, le manque de sommeil et les habitudes alimentaires sont largement reconnus comme les principaux déterminants de l’obésité chez l’enfant. Étant donné que les enfants adoptent de plus en plus des comportements défavorables à leur santé et compte tenu de la forte prévalence de l’obésité infantile en France, il est urgent d’améliorer l’efficacité des interventions visant à inverser ces tendances en concevant et en mettant en œuvre de nouvelles approches favorisant des modes de vie sains dès le plus jeune âge. Le programme Vivons en Forme (VIF), développé en France depuis 2011, est un programme de prévention communautaire, multi-acteurs et utilisant la méthodologie du marketing social pour promouvoir de saines habitudes de vie chez les enfants et leurs familles, notamment les familles plus touchées par l’obésité. Sa mise en œuvre repose sur la mobilisation des services des villes impliquées, en charge de l’éducation, de la restauration ou des activités périscolaires des enfants. L’objectif de cet article est de présenter une description détaillée de la méthodologie VIF, qui cible de façon itérative les thématiques liées au mieux manger, la lutte contre la sédentarité ou l’amélioration du sommeil chez les enfants. L’exemple de la thématique des écrans illustrera le processus mis en œuvre.</div></div><div><div>Sedentary behaviors, lack of sleep, and dietary habits are widely recognized as the main determinants of childhood obesity. Given that children are increasingly adopting behaviors detrimental to their health and considering the high prevalence of childhood obesity in France, it is urgent to improve the effectiveness of interventions aimed at reversing these trends by designing and implementing new approaches that promote healthy lifestyles from an early age. The Vivons en Forme (VIF) program, developed in France since 2011, is a community-based prevention program involving multiple stakeholders and using social marketing methodology to promote healthier lifestyles among children and their families, particularly those more affected by obesity. Its implementation relies on mobilizing city services involved in education, school meals, or extracurricular activities for children. The objective of this article is to provide a detailed description of the VIF methodology, which iteratively targets themes such as healthier eating, combating sedentary behavior, and improving children's sleep. The process is illustrated showcasing the topic of mitigating time spent in front of screens.</div></div>","PeriodicalId":43722,"journal":{"name":"CAHIERS DE NUTRITION ET DE DIETETIQUE","volume":"61 1","pages":"Pages 19-28"},"PeriodicalIF":0.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147636793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tissus adipeux brun et beige : exploration et rôle dans la physiologie humaine","authors":"Rémi Montané ,&nbsp;Raphael Alves de Souza ,&nbsp;Azalaïs Cros ,&nbsp;Emmanuel Gras ,&nbsp;Yannick Jeanson ,&nbsp;Jean-Charles Portais ,&nbsp;Armelle Yart ,&nbsp;Cédric Dray ,&nbsp;Louis Casteilla ,&nbsp;Isabelle Ader ,&nbsp;Audrey Carrière","doi":"10.1016/j.cnd.2026.01.002","DOIUrl":"10.1016/j.cnd.2026.01.002","url":null,"abstract":"<div><div>Le tissu adipeux brun est spécialisé dans la dissipation de l’énergie sous forme de chaleur, par le processus de thermogénèse de non-frisson. De nombreuses études chez les rongeurs ont montré le rôle majeur du tissu adipeux brun ainsi que celui du tissu adipeux beige – présentant des similitudes dans les propriétés métaboliques et sécrétoires mais également des différences qui restent encore à être mieux définies – dans la thermorégulation et dans le maintien de la balance énergétique. Chez l’homme, les tissus adipeux brun/beige sont très présents chez le nouveau-né, déclinent avec l’âge, et sont positivement associés à la santé cardiovasculaire et métabolique. Cependant, l’impact de ces tissus sur le métabolisme chez l’adulte est très controversé. Parallèlement à un potentiel rôle dans le maintien de l’homéostasie énergétique à l’échelle de l’organisme entier, ces tissus pourraient exercer des effets locaux par la création de microenvironnements spécifiques contribuant au bon fonctionnement d’organes présents à leur proximité. Dans cette revue, nous faisons le point sur la biologie de ces tissus aux capacités oxydatives remarquables, sur les méthodes de détection et sur les résultats d’études cliniques rétrospectives et prospectives étudiant leur rôle dans la santé humaine.</div></div><div><div>Brown adipose tissue is specialized in energy dissipation in the form of heat through the process of non-shivering thermogenesis. Numerous studies in rodents have demonstrated the major role of brown adipose tissue, as well as that of beige adipose tissue – which has similar metabolic and secretory properties but also differences that remain to be better defined – in thermoregulation and energy balance. In humans, brown/beige adipose tissues are very present in newborns, decline with age, and are positively associated with cardiovascular and metabolic health. However, the real impact of these tissues on human metabolism in adults remains highly controversial. In addition to their potential role in maintaining energy homeostasis at the whole organism level, these tissues may exert local effects by creating specific microenvironments that contribute to the proper functioning of tissues and organs present in their close proximity. In this review, we describe the biology of these tissues exhibiting remarkable oxidative capacities, the methods enabling their detection, and retrospective and prospective clinical studies investigating their role in human health.</div></div>","PeriodicalId":43722,"journal":{"name":"CAHIERS DE NUTRITION ET DE DIETETIQUE","volume":"61 1","pages":"Pages 100-114"},"PeriodicalIF":0.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147636794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Informations","authors":"","doi":"10.1016/j.cnd.2026.02.001","DOIUrl":"10.1016/j.cnd.2026.02.001","url":null,"abstract":"","PeriodicalId":43722,"journal":{"name":"CAHIERS DE NUTRITION ET DE DIETETIQUE","volume":"61 1","pages":"Pages 3-17"},"PeriodicalIF":0.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147636739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}