Fayoum University Medical Journal最新文献

{"title":"Cardiac affection in pediatric patients with β- thalassemia major.","authors":"Hanaa I. Mahmoud, Sara Abo Elnour","doi":"10.21608/fumj.2022.267874","DOIUrl":"https://doi.org/10.21608/fumj.2022.267874","url":null,"abstract":"","PeriodicalId":436341,"journal":{"name":"Fayoum University Medical Journal","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133531187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post intensive Care Complications and Mortality in Severe and Critically ill COVID 19 Patients","authors":"O. Momtaz, Tamer Sayed Abdel Mawla, A. Elkhateeb, E. Ahmed","doi":"10.21608/fumj.2022.267887","DOIUrl":"https://doi.org/10.21608/fumj.2022.267887","url":null,"abstract":"","PeriodicalId":436341,"journal":{"name":"Fayoum University Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133177623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Bovine Colostrum in Treatment of Gastroenteritis in Infant and Children","authors":"E. Ahmed, Hanaa I. Mahmoud, Remon M. Yousef","doi":"10.21608/fumj.2022.260461","DOIUrl":"https://doi.org/10.21608/fumj.2022.260461","url":null,"abstract":"and children in developing and developed countries. Bovine Colostrum (BC) is a rich source of nutrients and biologically active molecules essential for several specific functions such as defensive action, the modulation of the immune response, and the growth and repair of several tissues. The components of colostrum might intervene in various pathogenesis phases of several diseases, thus contributing to an improvement of clinical symptoms. Aim of the study: The study aimed to determine the role of bovine colostrum in acute gastroenteritis treatment in infants and children. Subjects and Methods: In the current study, 100 infants and children were recruited. Participants were divided into two groups according to the treatment with/without BC. The effect of treatment on the motion of diarrhea, consistency of diarrhea, frequency of other symptoms, occurrence of dehydration, and need for hospitalization were observed for seven days. Results: The study revealed statistically significant differences between the two groups regarding the motion of diarrhea, improvement of vomiting, dehydration, and need for hospitalization (P<0.05) Conclusions: The early use of BC in children with acute gastroenteritis might decrease the duration of hospitalization, vomiting, diarrhea, dehydration, electrolyte disturbance, and associated complications.","PeriodicalId":436341,"journal":{"name":"Fayoum University Medical Journal","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121122111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transvaginal Ultrasound evaluation of the Cesarean scar: relation between a niche and abnormal uterine bleeding","authors":"Abd El-Samie Abd El-Samie, Sahar Yehya, Mohamed Etman","doi":"10.21608/fumj.2022.260460","DOIUrl":"https://doi.org/10.21608/fumj.2022.260460","url":null,"abstract":"Introduction: Cesarean section (CS) is a critical lifesaving operation for both mother and child, and its use has increased dramatically over the last decade. Mirroring global trends, CS rates in Egypt have steadily increased, reaching 52% of all deliveries according to the most recent 2014 Egypt Demographic and Health Survey (EDHS) and representing more than a 100% increase in the CS rate since 2005. Aim of the study: To evaluate the relationship between the presence of a niche and abnormal uterine bleeding in women with a history of Cesarean section. Subjects and Methods: The current observational cross-sectional study was performed between October 2020 and May 2021. All women who had a Cesarean section performed in our hospital were asked to participate. 225 women were included and examined with transvaginal sonography (TVS) 6–12 months after the Cesarean section. The depth, volume, and residual myometrium were measured in the case of a niche. The shape was assessed according to a specified classification. Results: The prevalence of a niche on evaluation with TVS was 24.0%. Postmenstrual spotting was reported by 33.6% of women with a niche and 15.2% of women without a niche (P=0.002). The niche volume significantly differed between women with and without postmenstrual spotting (P=0.02). Most niches had a semicircular (50.4%) or triangular shape (31.6%). No significant relationship was identified between the body of the niche and postmenstrual spotting (P=0.19). Conclusions: Our results demonstrate that 24% of women with a history of Cesarean section have a niche when examined by TVS and that a niche is associated with postmenstrual spotting.","PeriodicalId":436341,"journal":{"name":"Fayoum University Medical Journal","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124753699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the role of maternal serum high sensitivity C- reactive protein correlation with total and differential leucocytic count in predicting outcome in threatened abortion","authors":"Abdelsamie Abdelsamie, Rehab Elsheshtawy, Hazem Abdel Hameed","doi":"10.21608/fumj.2022.260462","DOIUrl":"https://doi.org/10.21608/fumj.2022.260462","url":null,"abstract":"Introduction: Miscarriage is a common complication of pregnancy occurring in 15% to 20% of all clinically recognized pregnancies. In many cases, the cause of miscarriage cannot be identified; however, among the recognized risk factors of miscarriage are maternal age over 34 years and paternal age over 40 years, previous history of two or more miscarriages, and maternal autoimmune factors. Aim of the study: Maternal serum differential leucocytic count and high-sensitivity C-reactive protein (HSCRP) were evaluated in predicting spontaneous abortion in spontaneous pregnancies presenting with threatened spontaneous abortion. Subjects and methods: 100 pregnant women were divided into two equal groups: the threatened abortion group and the control group. Results: The mean values of WBCs, neutrophils, monocytes, and lymphocytes were significantly higher in the study group. Comparing the level of High sensitivity CRP among the studied groups showed the higher significant mean values of the high sensitivity- CRP in the sera of the study group than in the control group. Conclusion: The current study recommends that increased serum levels of total and differential leucocytic count and serum levels of High sensitivity- CRP are the possible mechanisms involved in the first trimester threatened miscarriage","PeriodicalId":436341,"journal":{"name":"Fayoum University Medical Journal","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127618506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between hysteroscopy finding and chronic Endometritis in Unexplained Primary Infertility","authors":"Abdelsamie Abdelsamie, M. Bakry, Sameh Abou-Beih","doi":"10.21608/fumj.2022.260464","DOIUrl":"https://doi.org/10.21608/fumj.2022.260464","url":null,"abstract":"Introduction: One of the most common conditions in a fertility clinic is unexplained infertility. Only recently, chronic endometritis (CE) has been linked to embryonic transplantation failure and infertility. Aim of the study: To evaluate the role of hysteroscopy in the diagnosis of chronic endometritis (CE) and to determine the correlation between hysteroscopic and histologic findings of CE in patients with unexplained primary infertility. Subjects and methods: The present study was conducted on 25 female patients under the age of 40 years attending the infertility clinic at Mataria teaching hospital complaining of unexplained primary infertility during the period from May 2018 to April 2019. Patients underwent office hysteroscopy (for evaluation of CE by visualized hysteroscopic features of CE as endometrial hyperemia), endometrial interstitial edema, micro-polyps, and visualized endometrial biopsies were obtained. Results: We found that 21 patients (84 %) had chronic endometritis by endometrial biopsies taken after being stained with CD138. The diagnostic accuracy of hysteroscopy in the diagnosis of CE in our study was 52%. The hysteroscopy sensitivity was 48%, the specificity was 75%, the positive predictive was 91%, and the negative predictive was 21%. Conclusion: Chronic endometritis should be considered in the workup of unexplained primary infertility. Hysteroscopy is a useful procedure with high diagnostic accuracy in chronic endometritis screening in asymptomatic infertile women however, endometrial biopsy should be complemented for the CE diagnosis.","PeriodicalId":436341,"journal":{"name":"Fayoum University Medical Journal","volume":"33 7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123038760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of COVID-19 associated cytokine storm in diabetic versus non diabetic patients","authors":"H. Hussein, Mohamed Gomaa, S. Mohammed","doi":"10.21608/fumj.2022.260456","DOIUrl":"https://doi.org/10.21608/fumj.2022.260456","url":null,"abstract":"a novel coronavirus, the so-called severe acute Abstract Introduction: COVID-19, a global pandemic has created a worldwide disaster since its first outbreak in December 2019 in Wuhan, China. Diabetic patients with COVID-19 have a worse prognosis and increased mortality. Cytokine storm is an aggressive inflammatory response to the SARS-CoV-2 virus and is associated with lung damage, multiple organ failure, and a bad COVID-19 prognosis. Aim of the study: The study aimed to evaluate the levels of some cytokine storm parameters in COVID-19 infection, besides a comparison of these levels between diabetic and nondiabetic Egyptian patients. Subjects and Methods: the current cross-sectional study recruited 80 adult individuals. All patients were divided into two groups: 42 diabetic patients with COVID-19 and 38 nondiabetic patients with COVID-19. Patients with diseases of inappropriate cytokine inflammatory load, such as autoimmune diseases or malignancies, were excluded. The medical history and clinical examination were performed. The cytokine storm inflammatory markers, such as C-reactive protein (CRP), Ferritin, Lactate dehydrogenase (LDH), D-dimer, Neutrophil-Lymphocyte Ratio (NLR), and Interleukine-6 (IL-6) were tested, in addition to the examination of the Glycemic state: HBA1C, FBS, and 2HPP. Duration of hospital admission and mode of respiratory support were recorded. Results: The results showed that 61% of diabetic patients needed more intensive care unit (ICU) admission than 36.8% of non-diabetics (P=0.025). The mean serum level of IL-6 was 126.55 ± 45.65 pg/ml in diabetic patients compared to 99.58 ± 52.77 pg/ml in non-diabetic, which was statistically significant (P=0.033). The ROC curve analysis showed that IL-6 was a significant marker of mortality (P<0.001) with a cut-off level >136 pg/mL at 95.65% sensitivity and 87.72% specificity. Furthermore, HBA1C was a significant marker of mortality (P<0.001) with a cut-off value >7.8 % at a sensitivity of 65.22 % and specificity of 63.16 %. Conclusion: Our study confirmed that diabetic patients had significantly earlier onset of cytokine storm, higher inflammatory response, longer hospital admission duration, higher admission rate to ICU, and more need for mechanical ventilation compared to non-diabetics.","PeriodicalId":436341,"journal":{"name":"Fayoum University Medical Journal","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116218667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Metabolic Syndrome in Different Phenotypes of Polycystic Ovary Syndrome and Pregnancy Rate","authors":"A. A. Abdel samie, A. Bosilah, Rehab Elsheshtawy","doi":"10.21608/fumj.2022.260458","DOIUrl":"https://doi.org/10.21608/fumj.2022.260458","url":null,"abstract":"Introduction: Polycystic ovary syndrome (PCOS) is considered one of the most common endocrine and metabolic disorders in women of reproductive age. According to Rotterdam diagnostic criteria, Insulin resistance (IR) plays an important role in the pathophysiology of PCOS. Aim of the study: To study the prevalence of metabolic syndrome in different phenotypes of PCOS and its relation to pregnancy rate. Subjects and methods: The current study recruited 100 patients who were primarily diagnosed with PCOS. These patients (aged between 18-30 years) complained of irregular menstruation, signs of hyperandrogenism, and infertility. Consents were taken from all patients. Cases were classified into four phenotypes (A, B, C, and D). After reporting the clinical history, physical examinations were performed by measuring arterial blood pressure (ABP), height, weight, body mass index (BMI), abdominal circumference (AC), and assessment of clinical signs of hyperandrogenism. the study found that the classic PCOS phenotype (A and B) is the most common representing about 60 % of patients. In comparison, the ovulatory phenotype (C) and the normal-androgenic phenotype (D) represented 27% and 13% of the patients, respectively. It also revealed a statistically significant difference between the four groups of PCOS regarding the presence of Metabolic Syndrome (P< 0.05), with the highest prevalence in phenotype A and the least prevalence in phenotype D. It also revealed a statistically significant difference between the four groups of PCOS regarding the presence of Metabolic Syndrome (P< 0.05), with the highest prevalence in phenotype A and the least prevalent phenotype D. Conclusion: Hyperinsulinemia and hyperandrogenemia can affect fertility in patients with PCOS leading to chronic anovulation.","PeriodicalId":436341,"journal":{"name":"Fayoum University Medical Journal","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122122214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of Serum Pro-adrenomedullin in Diagnosis of Neonatal Sepsis","authors":"N. Samra, Somaia Elgawhary, Wael Mohammed","doi":"10.21608/fumj.2022.252732","DOIUrl":"https://doi.org/10.21608/fumj.2022.252732","url":null,"abstract":"Introduction : Neonatal sepsis is a life-threatening condition that represents one of the major causes of morbidity and mortality among term and preterm infants. Pro-adrenomedullin (Pro-ADM) is the precursor of adrenomedullin, one of the inflammatory mediators. It is a more stable molecule, and its level has been reported to correlate with other acute phase reactants, such as interleukin-6 and C-reactive protein (CRP). Aim of the study: The study aimed to evaluate the value of serum pro-adrenomedullin measurement in the diagnosis of neonatal sepsis. Subjects and Methods: This cross-sectional study enrolled 50 neonates admitted to the neonatal ICU at Beni-suef General Hospital in 2017 and 2018 with clinical and laboratory evidence of sepsis. Normal healthy neonates (N = 30) were recruited as the control. All participants were subjected to history taking, clinical examination, and routine lab investigations, as well as, blood culture and measurement of serum Pro-ADM (using enzyme-linked immunosorbent assay). Results: The mean serum levels of both CRP and pro-ADM were significantly higher in the sepsis group compared to the healthy control neonates. Their diagnostic performances were found to be good with an overall accuracy of 80.4% and 91.3%, respectively. CRP and pro-ADM had comparable values for sensitivity (78% and 98%), specificity (84.4% and 81.2%), positive predictive value (88.6% and 88.9%), negative predictive value (71.1% and 96.3%), respectively. Conclusion: Pro-ADM seems to be a good, reliable diagnostic marker in neonatal sepsis. Pro-ADM levels above 20.1 indicate a high probability of sepsis diagnosis, and it may be a better marker of neonatal sepsis than CRP because it exceeded the performance of the latter.","PeriodicalId":436341,"journal":{"name":"Fayoum University Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129701772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medico-legal study of alleged sexual assault cases in Fayoum and Aswan governorates from 2010 -2016: comparative study","authors":"G. Al-Galad, S. Ghaleb, O. Mohamed, A. Saleh","doi":"10.21608/fumj.2022.252719","DOIUrl":"https://doi.org/10.21608/fumj.2022.252719","url":null,"abstract":"Introduction : Sexual assault is one of the most annoying crimes, which occur in all cultures, worldwide. That affects the health, reputation, and the victim, particularly, females. Aim of the study: The present study aims to recognize the most susceptible age group to be sexually assaulted and demonstrate physical injuries associated with the assault. Subjects and Methods: The study included 265 alleged sexual assault cases of different age groups. All participants were examined medico-legally in the Fayoum and Aswan Departments of Forensic Institute. We collected the retrospective data during the period starting from January 2010 to the end of December 2016. Results: The socio-demographic data of the sexually assaulted victims of the study showed a statistically significant association between the age and gender of the studied victims of sexual assault in Fayoum and Aswan. Male victims were more likely to be sexually assaulted in the age group <18 years (89.47%). Female cases in the age group (18-40 years old) in Fayoum were more subjected to sexual assault, while those less than (18 years old) in Aswan were more subjected to sexual assault. Conclusion: Evaluation of physical abuse yields solid medico-legal opinion in most cases. In contrast, the nature of genital and anal injuries was more confusing. That raises a lot of uncertainties. Therefore, rapid medico-legal assessment of the victims of sexual crimes along with the cautious interpretation of findings is advisable.","PeriodicalId":436341,"journal":{"name":"Fayoum University Medical Journal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127727655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}