Nepal Journal of Epidemiology最新文献_第2页

One year analysis of Prospective Memory Clinics Registry in Qatar: A Critical Tool for Dementia Research and Policy Planning. 卡塔尔前瞻性记忆诊所登记一年分析：痴呆症研究和政策规划的重要工具。

IF 1.7

Nepal Journal of Epidemiology Pub Date : 2024-09-02 eCollection Date: 2024-09-01 DOI: 10.3126/nje.v14i2.69364

Hanadi Al Hamad, Navas Nadukkandiyil, Mani Chandran, Pravija Talapan Manikoth, Brijesh Sathian

{"title":"One year analysis of Prospective Memory Clinics Registry in Qatar: A Critical Tool for Dementia Research and Policy Planning.","authors":"Hanadi Al Hamad, Navas Nadukkandiyil, Mani Chandran, Pravija Talapan Manikoth, Brijesh Sathian","doi":"10.3126/nje.v14i2.69364","DOIUrl":"10.3126/nje.v14i2.69364","url":null,"abstract":"Background: The Global Dementia Observatory (GDO) is a monitoring and accountability tool for the Global Action Plan on Public Response to Dementia 2017-25. Evidence from dementia registries may be utilized to better address WHO efforts in member countries, as well as to improve clinical practice and public health policy. The goal of this study was to analyze one-year data from a prospective memory clinic registry.Methods: This study was a baseline analysis of prospective memory clinics registry data of Qatar from January 1, 2023, through December 31, 2023.Results: This study investigated the demographic, clinical, and lifestyle characteristics of 464 participants who were enrolled in memory clinics. Mild neurocognitive disorders were the most prevalent diagnoses in both sexes, affecting 61.5% of male patients and 63.7% of female patients. Dementia was slightly more common in men (19.8% vs. 18.9%), although delirium was more common in women (1.9% vs. 0%). In terms of risk factors, the analysis revealed that females were more likely to be obese (36.8% vs. 16.7% in males), while males had higher rates of diabetes (61.1% vs. 51.9% in females), hypertension (69.4% vs. 62.7% in females), and smoking (17.1% vs. 3.8% in females).Conclusion: The findings of this study highlight the differences in dementia risk factors between genders and races, highlighting the need for customized interventions. Furthermore, the registry is a great resource for policymakers and healthcare professionals, providing evidence-based suggestions to improve dementia care, increase the well-being of patients and caregivers, and maximize resource allocation.","PeriodicalId":43600,"journal":{"name":"Nepal Journal of Epidemiology","volume":"14 2","pages":"1323-1332"},"PeriodicalIF":1.7,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11396565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bisphenol-A Leaching from Polycarbonate 5-Gallon Water Bottles in the UAE: A Comprehensive Study. 阿联酋 5 加仑聚碳酸酯水瓶中的双酚 A 沥滤：综合研究。

IF 1.7

Nepal Journal of Epidemiology Pub Date : 2024-06-30 eCollection Date: 2024-06-01 DOI: 10.3126/nje.v14i1.59934

Zahraa Khalid Ahmed Al-Tameemi, Razia Khanam, Preetha J Shetty

{"title":"Bisphenol-A Leaching from Polycarbonate 5-Gallon Water Bottles in the UAE: A Comprehensive Study.","authors":"Zahraa Khalid Ahmed Al-Tameemi, Razia Khanam, Preetha J Shetty","doi":"10.3126/nje.v14i1.59934","DOIUrl":"https://doi.org/10.3126/nje.v14i1.59934","url":null,"abstract":"Bisphenol A (BPA) is widely used around the world in the production of Polycarbonate (PC) plastics. Notably, the ubiquitous 5-gallon water bottles in the UAE are primarily made of PC plastic, making them a significant concern as bottled water is the region's main supply of drinking water. These bottles undergo temperature variations during storage and transportation, potentially leading to harmful BPA (Bisphenol A) leaching. This study analyzed 40 PC 5-gallon water bottles from two local brands A and B, with 20 bottles per brand, under two conditions: room temperature and outdoor sunlight exposure for a month. BPA levels were assessed at 0, 15, and 30 days, following ethical approval. Liquid-liquid extraction and ELISA assays were conducted, with comprehensive kit validation. The results revealed a significant increase in BPA concentration over time, particularly in bottles exposed to elevated temperatures (Day 30 outdoor-stored samples exhibited the highest concentration at 9.05 ± 2.30 μg/L). Brand B consistently exhibited higher BPA concentrations across different samples and environments. This study emphasizes the link between BPA content and storage time, highlighting the need for preventive measures to reduce BPA exposure. Individuals should be aware of potential health risks associated with prolonged storage in plastic containers and consider safer alternatives.","PeriodicalId":43600,"journal":{"name":"Nepal Journal of Epidemiology","volume":"14 1","pages":"1302-1309"},"PeriodicalIF":1.7,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11396560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Micro and Nano-plastic particles: What are they and do they effect cardiovascular health? 微塑料颗粒和纳米塑料颗粒：它们是什么？它们会影响心血管健康吗？

IF 1.7

Nepal Journal of Epidemiology Pub Date : 2024-06-30 eCollection Date: 2024-06-01 DOI: 10.3126/nje.v14i1.64183

Indrajit Banerjee, Jared Robinson, Brijesh Sathian, Indraneel Banerjee, Edwin R van Teijlingen, Bedanta Roy, Ashok Pratap Singh

引用次数: 0

Impact of nanoparticles on human health and disease. 纳米粒子对人类健康和疾病的影响。

IF 1.7

Nepal Journal of Epidemiology Pub Date : 2023-12-31 eCollection Date: 2023-12-01 DOI: 10.3126/nje.v13i4.61245

Bedanta Roy, Karthikeyan Murugesan, Maghimaa Mathanmohun, Brijesh Sathian

{"title":"Impact of nanoparticles on human health and disease.","authors":"Bedanta Roy, Karthikeyan Murugesan, Maghimaa Mathanmohun, Brijesh Sathian","doi":"10.3126/nje.v13i4.61245","DOIUrl":"10.3126/nje.v13i4.61245","url":null,"abstract":"Nanoparticles (NPs) are small particles with a surface area ranging from 1 to 100 nm in diameter that are rampantly used in different fields, e.g., medicine, engineering, and others. Because of their unique properties, such as their tiny size, magnetic properties, quantum size effects, and macroscopic quantum tunnelling effects, they are crucial for a wide range of potential applications. NPs play a significant role in the treatment of vascular disorders, the production of vaccines, and the development of drug carriers for diverse therapies due to their bioavailability, targeting ability, and efficacy. However, significant risks to the environment and health are also associated with it. NPs cause necrotic plasma membrane rupture or apoptosis, which leads to cell death. NPs interfere with cell signalling, endosomal membranes, and organelles like the nucleus or mitochondria, affecting their function. NPs cause autophagic cell death, which causes a stress response and sterile inflammation. The primary routes for the entry of NPs into the human body are inhalation, ingestion, and skin contact. NPs accumulate in the respiratory system based on their size, shape, and surface properties. NPs can cause lung inflammation and fibrosis, disrupt the endocrine system by attaching to hormone receptors, and produce reactive oxygen species (ROS) associated with DNA damage, oligospermia, and male infertility. Carcinogenic properties of NPs cause mutations, apoptosis, and inflammatory responses. Collaborative research between ecologists and epidemiologists may enlighten ways to reduce the harmful effects of NPs.","PeriodicalId":43600,"journal":{"name":"Nepal Journal of Epidemiology","volume":"13 4","pages":"1294-1297"},"PeriodicalIF":1.7,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10823378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139651874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Addressing the inequalities in global genetic studies for the advancement of Genetic Epidemiology. 解决全球遗传研究中的不平等问题，促进遗传流行病学的发展。

IF 1.7

Nepal Journal of Epidemiology Pub Date : 2023-12-31 eCollection Date: 2023-12-01 DOI: 10.3126/nje.v13i4.61271

Brijesh Sathian, Edwin van Teijlingen, Bedanta Roy, Russel Kabir, Indrajit Banerjee, Padam Simkhada, Hanadi Al Hamad

引用次数: 0

Nomophobia: An emerging problem 虚拟恐惧症：一个新出现的问题

IF 3.9

Nepal Journal of Epidemiology Pub Date : 2023-12-23 DOI: 10.3126/nje.v13i3.58932

Indrajit Banerjee, J. Robinson, A. Kashyap, B. Sathian

引用次数: 0

Need for evidence synthesis for quality control of healthcare decision-making 医疗决策质量控制需要证据综述

IF 3.9

Nepal Journal of Epidemiology Pub Date : 2023-12-23 DOI: 10.3126/nje.v13i3.61004

B. Sathian, E. V. Van Teijlingen, Israel Junior Borges Do Nascimento, M. Khatib, Indrajit Banerjee, P. Simkhada, Russell Kabir, Hanadi Al Hamad

{"title":"Need for evidence synthesis for quality control of healthcare decision-making","authors":"B. Sathian, E. V. Van Teijlingen, Israel Junior Borges Do Nascimento, M. Khatib, Indrajit Banerjee, P. Simkhada, Russell Kabir, Hanadi Al Hamad","doi":"10.3126/nje.v13i3.61004","DOIUrl":"https://doi.org/10.3126/nje.v13i3.61004","url":null,"abstract":"Systematic reviews that are out-of-date delay policymaking, create controversy, and can erode trust in research. To avoid this issue, it is preferable to keep summaries of the study evidence. Living evidence is a synthesis approach that provides up-to-date rigorous research evidence summaries to decision-makers. This strategy is particularly useful in rapidly expanding research domains, uncertain existing evidence, and new research that may impact policy or practice, ensuring that physicians have access to the most recent evidence. Addressing global challenges – ranging from public health crises to climate change or political instability - requires evidence-based judgements. An obsolete, biased, or selective information poses risks of poor decisions and resource misallocation. The relatively nascent practice of living evidence proves invaluable in maintaining continuous interest and team engagement. The concept of living evidence has been particularly relevant during the COVID-19 pandemic due to the rapidly evolving nature of the virus, the urgent need for timely information, and the continuous emergence of new research findings. Although the COVID-19 pandemic accelerated the adoption of evidence systems, researchers and funders of research should rigorously test the living-evidence model across diverse domains to further advance and optimize its methodology.","PeriodicalId":43600,"journal":{"name":"Nepal Journal of Epidemiology","volume":"10 3","pages":""},"PeriodicalIF":3.9,"publicationDate":"2023-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139161624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Strengthening Healthcare through Academic and Industry Partnership Research. 通过学术和行业合作研究加强医疗保健。

IF 3.9

Nepal Journal of Epidemiology Pub Date : 2023-08-31 eCollection Date: 2023-08-01 DOI: 10.3126/nje.v13i2.58243

Brijesh Sathian, Edwin van Teijlingen, Padam Simkhada, Indrajit Banerjee, Hemanth Kumar Manikyam, Russell Kabir

引用次数: 0

The effect of COVID-19 on the mental health of the people in the Indian subcontinent: A scoping review. 新冠肺炎对印度次大陆人民心理健康的影响：范围界定综述。

IF 1.7

Nepal Journal of Epidemiology Pub Date : 2023-08-31 eCollection Date: 2023-08-01 DOI: 10.3126/nje.v13i2.52766

Russell Kabir, Ancy Chandrababu Mercy Bai, Haniya Zehra Syed, Md Rakibul Hasan, Divya Vinnakota, Sujita Kumar Kar, Rakesh Singh, Brijesh Sathian, S M Yasir Arafat

{"title":"The effect of COVID-19 on the mental health of the people in the Indian subcontinent: A scoping review.","authors":"Russell Kabir, Ancy Chandrababu Mercy Bai, Haniya Zehra Syed, Md Rakibul Hasan, Divya Vinnakota, Sujita Kumar Kar, Rakesh Singh, Brijesh Sathian, S M Yasir Arafat","doi":"10.3126/nje.v13i2.52766","DOIUrl":"10.3126/nje.v13i2.52766","url":null,"abstract":"Indian subcontinent has high mental heath burden and low resources to cope the mental health challenges. Assessment of impact of COVID-19 pandemic on the mental health would help to prioritize the resource allocations. We aimed to assess the impact of COVID-19 on the mental health of people in the Indian subcontinent. Following the PRISMA 2020 guideline, a scoping review was performed by systematically searching the PubMed, Scopus, and Embase databases to identify original studies that assessed mental health conditions during the COVID-19 pandemic in the Indian subcontinent. In this review, a total of 34 studies conducted between 2020 and 2022 were analyzed. The prevalence of anxiety disorders was found to range widely, from 2.5% in North Indian urban slum to 53% in Bangladesh and 21.7% in Pakistan. Similarly, the prevalence of depression varied widely, with rates ranging from 3.5% in North India to 29.8% in Pakistan. The prevalence of stress-related problems ranged from 18.3% in Pakistan to 59.7% in Bangladesh. Factors such as female gender, married status, healthcare workers, and mental illness were identified as important predictors of anxiety and depressive disorders. The impact of COVID-19 pandemic on mental health in Indian subcontinent varies widely based on study population and methods. Therefore, a cautious interpretation is needed while generalizing the study results.","PeriodicalId":43600,"journal":{"name":"Nepal Journal of Epidemiology","volume":"13 2","pages":"1268-1284"},"PeriodicalIF":1.7,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10219160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Promising Future for Complex Innovative Trial Design in Clinical Research. 临床研究中复杂创新试验设计的前景。

IF 3.9

Nepal Journal of Epidemiology Pub Date : 2023-03-01 DOI: 10.3126/nje.v13i1.53722

Brijesh Sathian, Edwin van Teijlingen, Indrajit Banerjee, Mohammad Asim, Russell Kabir

引用次数: 0