Zahraa Khalid Ahmed Al-Tameemi, Razia Khanam, Preetha J Shetty
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引用次数: 0
Abstract
Bisphenol A (BPA) is widely used around the world in the production of Polycarbonate (PC) plastics. Notably, the ubiquitous 5-gallon water bottles in the UAE are primarily made of PC plastic, making them a significant concern as bottled water is the region's main supply of drinking water. These bottles undergo temperature variations during storage and transportation, potentially leading to harmful BPA (Bisphenol A) leaching. This study analyzed 40 PC 5-gallon water bottles from two local brands A and B, with 20 bottles per brand, under two conditions: room temperature and outdoor sunlight exposure for a month. BPA levels were assessed at 0, 15, and 30 days, following ethical approval. Liquid-liquid extraction and ELISA assays were conducted, with comprehensive kit validation. The results revealed a significant increase in BPA concentration over time, particularly in bottles exposed to elevated temperatures (Day 30 outdoor-stored samples exhibited the highest concentration at 9.05 ± 2.30 μg/L). Brand B consistently exhibited higher BPA concentrations across different samples and environments. This study emphasizes the link between BPA content and storage time, highlighting the need for preventive measures to reduce BPA exposure. Individuals should be aware of potential health risks associated with prolonged storage in plastic containers and consider safer alternatives.
双酚 A(BPA)在全球广泛用于聚碳酸酯(PC)塑料的生产。值得注意的是,在阿联酋,无处不在的 5 加仑水瓶主要由 PC 塑料制成,由于瓶装水是该地区的主要饮用水供应,因此这种水瓶备受关注。这些瓶子在储存和运输过程中会受到温度变化的影响,有可能导致有害的双酚 A(BPA)浸出。这项研究在室温和室外阳光照射两种条件下,对 40 个 PC 5 加仑水瓶进行了分析,这些水瓶分别来自当地的两个品牌 A 和 B,每个品牌 20 个水瓶,分析时间为一个月。在获得伦理批准后,分别在 0 天、15 天和 30 天对双酚 A 水平进行了评估。进行了液液萃取和酶联免疫吸附测定,并对试剂盒进行了全面验证。结果表明,随着时间的推移,双酚 A 的浓度明显增加,尤其是在暴露于高温下的瓶子中(第 30 天室外存放的样品浓度最高,为 9.05 ± 2.30 μg/L)。在不同的样品和环境中,品牌 B 始终表现出较高的双酚 A 浓度。这项研究强调了双酚 A 含量与储存时间之间的联系,突出了采取预防措施减少双酚 A 暴露的必要性。人们应该意识到长期储存在塑料容器中对健康造成的潜在风险,并考虑使用更安全的替代品。
期刊介绍:
The Nepal Journal of Epidemiology is a international journal that encompasses all aspects of epidemiology. The journal encourages communication among those engaged in the research, teaching, and application of epidemiology of both communicable and non-communicable disease, including research into health services and medical care. Also covered are new methods, epidemiological and statistical, for the analysis of data used by those who practise social and preventive medicine. It provides the most up-to-date, original, well designed, well interpreted and significant information source in the multidisciplinary field of epidemiology. We publish manuscripts based on the following sections: 1.Short communications 2.Current research trends 3.Original research 4.Case reports 5.Review articles 6.Letter to editor