Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy最新文献

{"title":"Machine learning pipeline with custom grid search for colorectal Raman spectroscopy data","authors":"Daniela Janstová ,&nbsp;Jakub Tomeš ,&nbsp;Jan Vališ ,&nbsp;Alla Synytsya ,&nbsp;Zuzana Kováčová ,&nbsp;Jaromír Petrtýl ,&nbsp;Vladimír Setnička ,&nbsp;Jan Mareš","doi":"10.1016/j.saa.2025.126749","DOIUrl":"10.1016/j.saa.2025.126749","url":null,"abstract":"<div><div>Colorectal cancer remains a major health burden, and its early detection is crucial for effective treatment. This study investigates the use of a handheld Raman spectrometer in combination with machine learning to classify colorectal tissue samples collected during colonoscopy. A dataset of 330 spectra from 155 participants was preprocessed using a standardized pipeline, and multiple classification models were trained to distinguish between healthy and pathological tissue.</div><div>Due to the strong class imbalance and limited data size, a custom grid search approach was implemented to optimize both model hyperparameters and preprocessing parameters. Unlike standard GridSearchCV, our method prioritized balanced accuracy on the test set to reduce bias toward the dominant class. Among the tested classifiers, the Decision Tree (DT) and Support Vector Classifier (SVC) achieved the highest balanced accuracy (71.77% for DT and 70.77% for SVC), outperforming models trained using traditional methods.</div><div>These results demonstrate the potential of Raman spectroscopy as a rapid, non-destructive screening tool and highlight the importance of tailored model selection strategies in biomedical applications. While this study is based on a limited dataset, it serves as a promising step toward more robust classification models and supports the feasibility of this approach for future clinical validation.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"345 ","pages":"Article 126749"},"PeriodicalIF":4.6,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144860565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eu3+ doped carbon dots as a ratiometric fluorescence probe for highly sensitive detection of trace tetracycline in milk","authors":"Yachu Meng,&nbsp;Xincheng Sun,&nbsp;Jinling Xing,&nbsp;Chuan Dong","doi":"10.1016/j.saa.2025.126811","DOIUrl":"10.1016/j.saa.2025.126811","url":null,"abstract":"<div><div>The Eu³⁺-doped carbon dots (CDs-Eu³⁺) with high sensitivity and ratiometric fluorescence property is constructed as a luminescence probe for detection of tetracycline (TC). The as-prepared probe emits intrinsic blue fluorescence at 443 nm (quantum yield: 8.7%), characteristic of carbon dots (CDs). In the presence of TC, the probe demonstrate a dual response mechanism: the blue fluorescence of probe is selectively quenched via inner filter effect (IFE). Simultaneously, the TC induced antenna effect enhances the characteristic Eu³⁺ emission at 620 nm through chelation. The ratio of fluorescence intensity I₆₂₀/I₄₄₃ increases linearly in the TC concentration range of 0.01 μM to 240 μM with low detection limit of 3.83 nM. The probe exhibits remarkble sensitivity and selectivity, successfully applied in TC detection from milk samples with recoveries between 97.70 and 104.9%. This approach lays the groundwork for detecting multiple antibiotic residues across various samples. Furthermore, to facilitate practical applications, we constructed a sensing system utilizing smartphones which enables rapid, facile, and visual TC detection, which may offer a promising utilization for real-time and semi-quantitative assay of TC.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"345 ","pages":"Article 126811"},"PeriodicalIF":4.6,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144841194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reversible solid-state chromatic luminescence photoswitching in a dual-emitting MOF hybrid for advanced anticounterfeiting","authors":"Xuefang Huang ,&nbsp;Zixian Wu ,&nbsp;Junzheng Luo,&nbsp;You Zhou","doi":"10.1016/j.saa.2025.126812","DOIUrl":"10.1016/j.saa.2025.126812","url":null,"abstract":"<div><div>The engineering of smart materials exhibiting solid-state chromatic photoluminescence (PL) switching under light stimuli remains critically imperative for next-generation anticounterfeiting technologies. Here, we present a dual-emitting metal organic framework (MOF) hybrid that exhibits light-responsive chromatic PL switching in the solid state. This hybrid is constructed by encapsulating spiropyran dye molecules within a robust, luminescent zirconium-based MOF host, PCN-128 W. The host features a highly porous structure with large open channels, which facilitate dye encapsulation and provide the necessary conformational freedom for spiropyran photoisomerization. The host–guest confinement not only ensures close proximity for efficient intermolecular coupling, but also significantly enhances the dye's PL efficiency by suppressing the nonradiative decay pathways that exist in solid aggregates. Leveraging efficient host-guest Förster resonance energy transfer (FRET), the resulting hybrid exhibits weak blue emission (481 nm) from the MOF and strong red emission (634 nm) from the dye. Upon visible light irradiation, spiropyran undergoes photoisomerization from its open-ring (MC) to closed-ring (SP) form, leading to a rapid PL color switch from red to blue. This transition is driven by enhanced host emission coupled with quenched dye emission due to FRET deactivation. The PL color change is fully reversible, with dark treatment triggering spiropyran's return to the MC form and FRET reactivation. Time-resolved PL measurements confirm the dynamic modulation of FRET via dye isomerization. Motivated by these results, we designed and fabricated anticounterfeiting patterns using a high-security triple-layered information encryption strategy, demonstrating the promising potential of this hybrid in advanced information anticounterfeiting.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"345 ","pages":"Article 126812"},"PeriodicalIF":4.6,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144810171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly SERS active composite of silver nanospheres-decorated Ag nanostar/ZIF-8 for determination of diquat and thiram residues","authors":"Wei Zhang ,&nbsp;Kuang Luo ,&nbsp;Wenjie Chen,&nbsp;Min Chen,&nbsp;Ning Cai,&nbsp;Jumei Li","doi":"10.1016/j.saa.2025.126813","DOIUrl":"10.1016/j.saa.2025.126813","url":null,"abstract":"<div><div>In surface-enhanced Raman scattering (SERS) measurements, the creation of “hot spots” and the effective concentration of analytes in these areas are crucial for enhancing detection sensitivity. In this work, a novel composite with highly SERS activity, Ag nanospheres decorated Ag nanostar/ZIF-8 composite (Ag NS/ZIF-8/Ag) was achieved via first coating the Ag nanostars with the metal-organic framework ZIF-8, known for its strong molecular adsorption capabilities, followed by the electrostatic self-assembly of Ag nanospheres. The composites produce numerous hotspots due to the abundant plasmonic nanogaps, including the interstitial space between the Ag nanostar and Ag nanospheres, as well as internanogaps between neighboring Ag nanospheres, resulting in outstanding SERS performance. It was successfully applied for the quantitative and simultaneous detection of diquat and thiram in fruit juice, achieving detection limits of 5.0 × 10⁻⁸ mol/L and 1 × 10⁻⁸ mol/L, respectively, with recovery rates ranging from 86.6 % to 118.4 %. Notably, under UV light exposure, the composite was able to degrade pesticides efficiently within 80 min. Additionally, its reusability was demonstrated by sustaining strong SERS activity over five continuous detection cycles. These results emphasize the capability of Ag NS/ZIF-8/Ag composites for sensitive pesticide detection via SERS.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"345 ","pages":"Article 126813"},"PeriodicalIF":4.6,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144810169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Halogen substituted 4-thio-2′-deoxyuridines as photosensitizers for the photodynamic therapy of prostate cancer. An in vitro study","authors":"Anna Czaja,&nbsp;Magdalena Datta,&nbsp;Janusz Rak,&nbsp;Magdalena Zdrowowicz","doi":"10.1016/j.saa.2025.126802","DOIUrl":"10.1016/j.saa.2025.126802","url":null,"abstract":"<div><div>Photodynamic therapy (PDT) is a minimally invasive modality that employs a photosensitizer (PS) and light exposure source within the PS's optimal absorption range to induce selective cytotoxic effects. This study investigates 5′-bromo-4-thio-2′-deoxyuridine (BrSdU) and 5′-iodo-4-thio-2′-deoxyuridine (ISdU), both modified nucleoside (MN)-based photosensitizers. The presence of the sulfur atom in their thionucleoside structures shifts their maximum absorption to approximately 350 nm, enabling efficient activation under UVA irradiation and minimizing the inner filter effect observed with conventional halogenated nucleosides. MTT assays confirm that BrSdU and ISdU exhibit negligible dark cytotoxicity in PC3 prostate cancer cells. In contrast, clonogenic assays reveal that UVA irradiation of BrSdU/ISdU-labeled cells significantly enhances cell lethality. Mechanistic analysis demonstrates that the combined treatment induces (1) a decrease in viable cell population with a concomitant increase in early apoptotic cells, (2) G2/M phase cell cycle arrest, (3) elevated levels of DNA double-strand breaks compared to UVA-only controls, and (4) no significant alteration in intracellular reactive oxygen species (ROS) levels. These results suggest that BrSdU and ISdU function as effective UVA-activated photosensitizers, mediating DNA-targeted photodynamic damage through mechanisms largely independent of ROS generation, and hold promise for further development in targeted cancer therapies.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"345 ","pages":"Article 126802"},"PeriodicalIF":4.6,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A colorimetric and ratiometric fluorescent probe for metabisulfite detection and its application in food safety analysis","authors":"Xianjun Xu,&nbsp;Yanxin Zhang,&nbsp;Liting Tang,&nbsp;Liqiang Yan","doi":"10.1016/j.saa.2025.126800","DOIUrl":"10.1016/j.saa.2025.126800","url":null,"abstract":"<div><div>Metabisulfite (S₂O₅²⁻) plays a critical role in the chemical, pharmaceutical, and food industries. However, excessive residues or prolonged exposure to S₂O₅²⁻ can pose significant risks to human health. To enable rapid, effective, and convenient detection of its content, a colorimetric and ratiometric fluorescent probe (CQ1) based on the coumarin-quinoline scaffold has been developed. This probe allows for the highly selective detection of S₂O₅²⁻ through characteristic fluorescence ratio variations (F₄₈₅/F₇₀₆), with a low limit of detection (LOD) of 1.68 μM, relative standard deviations (RSD) ranging from 1.05 % to 2.67 %, and recovery rates between 91.6 % and 102.57 %. The probe has been successfully utilized in diverse practical applications, including portable test strips, and wearable gloves for dynamic monitoring of S₂O₅²⁻ residues on vegetable surfaces, as well as direct ratiometric and colorimetric detection of S₂O₅²⁻ in preserved fruits and nuts. These findings demonstrate that the probe offers a promising method for the monitoring and analysis of S₂O₅²⁻ in the field of food safety.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"345 ","pages":"Article 126800"},"PeriodicalIF":4.6,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144828009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial-extract mediated gold nanoparticles: Enhanced uptake, oxidative stress, and cytotoxicity in HepG2 cells with biofilm inhibition and antibiotic synergy","authors":"Atheer Alamrani,&nbsp;Jayda G. Eldiasty","doi":"10.1016/j.saa.2025.126763","DOIUrl":"10.1016/j.saa.2025.126763","url":null,"abstract":"<div><h3>Background</h3><div>Gold nanoparticles (AuNPs) are widely studied for cancer therapy due to their biocompatibility and unique physicochemical properties. However, limitations in cellular uptake and biological activity remain. Green synthesis using bacterial extracts offers a sustainable alternative that may improve therapeutic outcomes. This study compares the biological and physicochemical performance of chemically synthesized AuNPs <strong>(Chem-AuNPs)</strong> with those produced via bacterial biosynthesis <strong>(Bacterial-AuNPs)</strong> in HepG2 liver cancer cells and pathogenic bacteria. AuNPs were synthesized via classical citrate reduction or bacterial extract-mediated biosynthesis. Characterization included UV–Vis, TEM, DLS, XRD, and EDX. Cytotoxicity, ROS generation, mitochondrial membrane potential (ΔΨm), and gene expression were assessed in HepG2 cells. Biofilm inhibition and antibiotic synergy (checkerboard assay) were evaluated against multi-drug resistant bacterial strains. Bacterial-AuNPs were smaller and more monodisperse (PDI = 0.18) compared to Chem-AuNPs (PDI = 0.32)., with enhanced cellular uptake (95 % vs. 70 %) and ROS induction (3.0- vs. 2.0-fold). NAC co-treatment confirmed ROS-mediated cytotoxicity. Bacterial-AuNPs significantly inhibited biofilm formation and exhibited strong synergy with antibiotics (FICI ≤0.5) in key pathogens. The primary uptake mechanism was identified as clathrin-mediated endocytosis, with caveolae-mediated uptake contributing at higher concentrations. <strong>Bacterial-AuNPs</strong> demonstrate superior cellular uptake, ROS generation, and mitochondrial dysfunction, key mechanisms in cancer cell apoptosis. Biogenically synthesized AuNPs demonstrate superior anticancer and antimicrobial activity compared to chemically synthesized counterparts. These findings highlight the potential of bacterial-extract-mediated AuNPs as multifunctional therapeutic agents in oncology and infectious disease contexts.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"345 ","pages":"Article 126763"},"PeriodicalIF":4.6,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144841068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluorescent sensor for bisphenol S based on pH adjustment and polydopamine nanoparticles","authors":"Anqi Hu ,&nbsp;Anlan Huang ,&nbsp;Yunpeng Shang ,&nbsp;Chaoqun Ma ,&nbsp;Lei Li ,&nbsp;Taiqun Yang ,&nbsp;Hui Gao ,&nbsp;Jiao Gu ,&nbsp;Chun Zhu ,&nbsp;Guoqing Chen","doi":"10.1016/j.saa.2025.126799","DOIUrl":"10.1016/j.saa.2025.126799","url":null,"abstract":"<div><div>Initially, it was considered as a feasible solution to replace the harmful bisphenol A with structurally similar bisphenol S (BPS). However, with the deepening of research, BPS has also been pointed out to have similar endocrine-disrupting effects and physiological hazards to bisphenol A. Therefore, it is necessary to develop an efficient and convenient method for BPS detection. By combining pH adjustment and the polydopamine nanoparticles (DPA-PDs), which were synthesized according to a one-step hydrothermal method with dopamine hydrochloride as the precursor, a ratiometric fluorescence sensing platform for BPS has been constructed in this work. The analyte BPS has weak fluorescence in acidic and neutral environments. However, deprotonated BPS exhibits stronger fluorescence emission at 460 nm in an alkaline environment, and the synchronously enhanced absorption bands of BPS overlaps with both the excitation spectrum and emission spectrum of DPA-PDs. Consequently, the fluorescence of DPA-PDs can be quenched by BPS based on the inner filtration effect, and the intrinsic fluorescence of BPS is positively correlated with the concentration of BPS. The limit of detection for the single-signal sensing model based on the intrinsic fluorescence of BPS is as low as 0.075 μM, and the limit of detection for the ratiometric fluorescence sensing model based on the enhanced BPS versus quenched DPA-PDs is 0.257 μM. The proposed method does not require composite materials with complex preparation processes, and the advantages of sensitivity, rapidity and simplicity are conducive to the application in BPS monitoring.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"345 ","pages":"Article 126799"},"PeriodicalIF":4.6,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144826746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of spectroelectrochemical processes of JC-1 cyanine dye combined with gold nanoparticles, an important indicator of mitochondrial membrane potential: theoretical and EC-SERS studies","authors":"Kacper Jędrzejewski ,&nbsp;Oliwier Misztal ,&nbsp;Janusz Cukras ,&nbsp;Krystian Pupel ,&nbsp;Łukasz S. Borowski ,&nbsp;Barbara Pałys","doi":"10.1016/j.saa.2025.126801","DOIUrl":"10.1016/j.saa.2025.126801","url":null,"abstract":"<div><div>JC-1 dye (5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide) exhibits unique fluorescent properties related to its ability to form monomers and J-type aggregates depending on the redox potential. In this work, electrochemical surface-enhanced Raman spectroscopy (EC-SERS) was used for the first time to monitor the structural changes of JC-1 dye in the presence of gold nanoparticles in real time under the influence of the potential. DFT modeling and PED analysis of JC-1 monomer provided assignments for its key vibrational modes. These assignments helped interpret the spectral changes observed experimentally upon J-aggregate formation, facilitating the identification of bands characteristic of the aggregated state and related molecular reorientations. The influence of electrode type, electrolyte pH and laser wavelength on the change in the SERS spectrum was investigated. The results showed that EC-SERS is a sensitive method capable of detecting subtle conformational and orientational changes of JC-1 molecules, including reorientation with respect to the electrode surface and specific interactions with gold atoms. These observations open new possibilities for using EC-SERS to analyze complex fluorescent and electroactive systems under electrochemically controlled conditions.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"345 ","pages":"Article 126801"},"PeriodicalIF":4.6,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144810168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orange ratiometric fluorescent probe for sensitive detection of phoxim","authors":"Xinyue Huang ,&nbsp;Lei Jiang ,&nbsp;Lin Yuan ,&nbsp;Wensi Ma ,&nbsp;Xintao Cui ,&nbsp;Jiaxuan Liu ,&nbsp;Xiuling Ji ,&nbsp;YujiaoTu","doi":"10.1016/j.saa.2025.126785","DOIUrl":"10.1016/j.saa.2025.126785","url":null,"abstract":"<div><div>Pesticides are chemicals widely utilized in various industries, particularly agriculture, to manage pests and enhance crop yields. However, the excessive use of pesticides, such as phoxim, poses threats to the environment, food safety, and human health. Thus, it is crucial to use pesticides judiciously, limiting their application to what is necessary. Fluorescent probes have garnered attention for their cost-effectiveness, straightforward preparation, and high sensitivity, positioning them as promising candidates for detecting phoxim. In this context, orange ratiometric fluorescent carbon dots were synthesized using Rhodamine B and NaOH as precursors through a hydrothermal method. The synthesized Rh B<img>Na CDs were then purified via dialysis, thin-layer chromatography, and chromatographic columns to develop an accurate and precise ratiometric fluorescent probe. This nanoprobe demonstrated excellent linear ranges for detecting phoxim levels in various food samples. It exhibited a low detection limit of 4.486 nM for phoxim concentrations ranging from 0 to 25 μM and can accurately detect concentrations between 25 and 250 μM. Moreover, it proved sensitive in identifying phoxim content in samples of red grapes, green grapes, tomatoes, and pitayas.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"345 ","pages":"Article 126785"},"PeriodicalIF":4.6,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144810170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}