Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy最新文献_第7页

Aliphatic amines – Sensing application in aqueous media using supramolecularly stacked acriflavine dye on graphene oxide 脂肪族胺-在氧化石墨烯上使用超分子堆叠吖啶黄染料在水介质中的传感应用

IF 4.3 2区化学

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Pub Date : 2025-04-12 DOI: 10.1016/j.saa.2025.126233

Pavitra Rajendran , Jamuna Kannan , Lakshminarayanan Piramuthu , Erumaipatty Rajagounder Nagarajan , Shanmugam Sivakumar , Narayanan Selvapalam

{"title":"Aliphatic amines – Sensing application in aqueous media using supramolecularly stacked acriflavine dye on graphene oxide","authors":"Pavitra Rajendran , Jamuna Kannan , Lakshminarayanan Piramuthu , Erumaipatty Rajagounder Nagarajan , Shanmugam Sivakumar , Narayanan Selvapalam","doi":"10.1016/j.saa.2025.126233","DOIUrl":"10.1016/j.saa.2025.126233","url":null,"abstract":"<div><div>Supramolecularly stacked acriflavine dye on graphene oxide (GO-Acy) was utilized for the first time to detect aliphatic amines, making it a highly sensitive and selective material. This method involved developing a distinctive, discriminative, and highly selective fluorescent sensor that displayed a ’turn-on’ response to aliphatic amines. The sensor probe operated through supramolecular host–guest interactions between the amines and dyes, enabling the detection of aliphatic amines. Upon the interaction of aliphatic amines with bound Acy dye on graphene oxide, the fluorescent sensor exhibited a release of Acy dyes and a rapid appearance of fluorescence. GO-Acy demonstrated high selectivity for 1,4-butanediamine (BD), exhibiting strong fluorescence intensity and accurately distinguishing it from various aliphatic amines, aromatic amines, and amino acids. The fluorescene emission intensities of GO-Acy at λem = 510 nm was observed after exposure to different amines, with an excitation wavelength of GO-Acy at λex = 450 nm. In addition to its high selectivity, the sensor probe also exhibited excellent sensitivity towards BD, with a limit of detection (LOD) of 9.9 nM. This graphene-based material proved to be a highly effective tool for detecting aliphatic amines in aqueous media, requiring no special experiments while providing both good selectivity and sensitivity. Additionally, GO-Acy@CB[7] demonstrated diverse responses to aliphatic amines, suggesting its ability to discriminate between them through fluorescence quenching. GO-Acy has proven effective in monitoring fish products that release amine vapors during decomposition. Furthermore, test paper strips made with GO-Acy could quickly detect amines in actual fish samples, highlighting the potential of GO-Acy for food quality inspection.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"338 ","pages":"Article 126233"},"PeriodicalIF":4.3,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbazole-disulfonamide-containing macrocycles as powerful anion receptors with tunable selectivity 含咔唑-二磺酰胺的大环作为选择性可调的强阴离子受体

IF 4.3 2区化学

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Pub Date : 2025-04-12 DOI: 10.1016/j.saa.2025.126235

Qinrong Yang , Sha Li , Hong Li , Shengping Liu , Ningjin Zhang , Tao Sun , Xiaoping Bao

{"title":"Carbazole-disulfonamide-containing macrocycles as powerful anion receptors with tunable selectivity","authors":"Qinrong Yang , Sha Li , Hong Li , Shengping Liu , Ningjin Zhang , Tao Sun , Xiaoping Bao","doi":"10.1016/j.saa.2025.126235","DOIUrl":"10.1016/j.saa.2025.126235","url":null,"abstract":"<div><div>The design of synthetic anion receptors with potent anion binding and customizable anion selectivity under competitive solvent conditions remains challenging. Herein, we report easily-synthesized 1,8-disulfonamidocarbazole- and 3,5-diamidopyridine-based hybrid macrocycles 1−3 and reveal their strong anion recognition properties as determined by 1H NMR/UV−vis titration studies, X-ray diffraction measurements, and DFT calculations. While the dithioamidopyridine-based macrocycle 2 displayed strong and selective binding of AcO− in DMSO, modification of the selectivity pattern towards the more basic F− anion was achieved by replacing the thioamides moieties to amides (macrocycle 1). For macrocycle 3 (bearing pyridine N-oxide core), no selectivity was observed among F−, AcO−, and H2PO4− ions. The demonstration of tunable anion selectivity by slight structural modifications in our macrocycles is informative for developing structurally simple anion receptors with the desired selectivity for transmembrane anion transport, anion sensing, and anion sequestration applications.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"339 ","pages":"Article 126235"},"PeriodicalIF":4.3,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143842990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

One-pot synthesis of fluorescent nanoprobes based on D-cys-based CDs and quantitative detection of lysine enantiomers d -cys基CDs荧光纳米探针的一锅合成及赖氨酸对映体的定量检测

IF 4.3 2区化学

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Pub Date : 2025-04-12 DOI: 10.1016/j.saa.2025.126143

Jinqiu Li, Fanghao Wang, Hao Zhang, Duxia Cao, Ruifang Guan

{"title":"One-pot synthesis of fluorescent nanoprobes based on D-cys-based CDs and quantitative detection of lysine enantiomers","authors":"Jinqiu Li, Fanghao Wang, Hao Zhang, Duxia Cao, Ruifang Guan","doi":"10.1016/j.saa.2025.126143","DOIUrl":"10.1016/j.saa.2025.126143","url":null,"abstract":"<div><div>The recognition of amino acid enantiomers is of great significance in drug research and disease diagnosis. However, the similar physical and chemical properties of enantiomers make chiral recognition challenging. Optical characterization is a promising approach to distinguish enantiomers. Carbon dots (CDs) have attracted widespread attention due to their simple synthesis, high economic benefits, and good biocompatibility. Chiral carbon dots, as fluorescent probes, have gradually received more attraction. Here, a fluorescence probe (CYS-CDs + Cu2+) was constructed using D-Cys as chiral source to synthesize chiral carbon dots (CYS-CDs), and Cu2+ as inducer to recognize the chirality of lysine enantiomers(L-/D-Lys). And then, based on the ability of Cu2+ to quench the fluorescence of CYS-CDs and L-Lysine (L-Lys) could restore the fluorescence of the CYS-CDs + Cu2+ probe, so achieve an “on–off–on” detection mode to detect L-Lys. On the contrary, D-Lys cannot restore the fluorescence of CYS-CDs + Cu2+. The probe can distinguish lysine enantiomers not only by fluorescence spectra but also by circular dichroism spectra. And, the probe can be used for the quantitative detection of L-Lys by fluorescence method, of which the detection range is 0–520 μM, and the limit of detection is only 13.70 μM. In addition, a paper-based fluorescent senor was constructed on this basis. This work may be of practical significance to expand the recognition method of amino acid enantiomers.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"339 ","pages":"Article 126143"},"PeriodicalIF":4.3,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A novel fluorescent probe with large stokes shift based on naphthalimide and phenanthroline for specific detection of Ag+ and its application in living cells imaging 基于萘酰亚胺和菲罗啉的新型大斯托克斯位移荧光探针对银离子的特异性检测及其在活细胞成像中的应用

IF 4.3 2区化学

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Pub Date : 2025-04-11 DOI: 10.1016/j.saa.2025.126222

Chenglu Zhang, Jinghao Guo, Yang Zhang, Cui Liu

引用次数: 0

Up-conversion emission characteristics and temperature measurement of core-shell structured NaGdF4: Er3+Tm3+/Yb3+@NaYbF4: xYb3+ (x = 25, 50) phosphors 核壳结构NaGdF4: Er3+Tm3+/Yb3+@NaYbF4: xYb3+ (x = 25,50)荧光粉的上转换发射特性及温度测量

IF 4.3 2区化学

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Pub Date : 2025-04-11 DOI: 10.1016/j.saa.2025.126223

Li Xuecheng, Hao Haoyue, Li Liang

{"title":"Up-conversion emission characteristics and temperature measurement of core-shell structured NaGdF4: Er3+Tm3+/Yb3+@NaYbF4: xYb3+ (x = 25, 50) phosphors","authors":"Li Xuecheng, Hao Haoyue, Li Liang","doi":"10.1016/j.saa.2025.126223","DOIUrl":"10.1016/j.saa.2025.126223","url":null,"abstract":"<div><div>In this study, the intensity and properties of up-conversion luminescence in core–shell structured NaGdF4: Er3+/Tm3+/Yb3+@NaGdF4: Yb3+ phosphors were investigated. After coating the NaGdF4: 0.5Er3+/0.5Tm3+/30Yb3+ (0.5Er/0.5Tm/30Yb) core with NaGdF4: xYb3+ (x = 25, 50) shells, the luminescence intensity of the phosphors was improved. The enhancement factor reached to 3.97 (x = 25) and 1.15 (x = 5) respectively. Owing to the different increase of up-conversion luminescence peak, the emission color changed from blue-green to yellowish-green in NaGdF4: 0.5Er3+/0.5Tm3+/30Yb3+@NaGdF4: 25Yb3+ (0.5Er/0.5Tm/30Yb@25Yb) phosphors. Additionally, the temperature sensing properties of the 0.5Er/0.5Tm/30Yb@25Yb phosphors were examined. A maximum relative sensitivity (Sr) of 0.013 K−1 was observed at 303 K based on florescence intensity ratio of two green emission. And a higher Sr of 0.034 K−1 was recorded at 403 K based on the ratio of green (540 nm) and near-red emissions (800 nm). These findings not only deepen the understanding of the up-conversion processes in core–shell structured phosphors but also promote the development of rare-earth ion core–shell structures for applications in temperature sensing and luminescent displays.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"338 ","pages":"Article 126223"},"PeriodicalIF":4.3,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143824302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A portable platform integrated with smartphones for rapid lactic acid analysis via ratiometric fluorescent imaging 与智能手机集成的便携式平台，可通过比率荧光成像技术进行快速乳酸分析

IF 4.3 2区化学

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Pub Date : 2025-04-11 DOI: 10.1016/j.saa.2025.126224

Wen-Ru Wu , Jing Li , Yue Lin , Fang Luo , Cui-Ying Lin , Bin Qiu , Zhen-Yu Lin , Jian Wang , Fang-Zheng Huang

引用次数: 0

Concentration-Dependent SERS of P3HT in the Ag/P3HT/MBA System: A charge transfer study Ag/P3HT/MBA体系中P3HT浓度依赖性SERS：电荷转移研究

IF 4.3 2区化学

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Pub Date : 2025-04-11 DOI: 10.1016/j.saa.2025.126220

Dongyu Han , Nannan Yang , Xinrui Liu , Chunqiu Xia , Yoonseop Byun , Shuang Guo , Jiku Wang , Lei Chen , Young Mee Jung

{"title":"Concentration-Dependent SERS of P3HT in the Ag/P3HT/MBA System: A charge transfer study","authors":"Dongyu Han , Nannan Yang , Xinrui Liu , Chunqiu Xia , Yoonseop Byun , Shuang Guo , Jiku Wang , Lei Chen , Young Mee Jung","doi":"10.1016/j.saa.2025.126220","DOIUrl":"10.1016/j.saa.2025.126220","url":null,"abstract":"<div><div>Organic semiconductors are widely attracting attention as a new type of surface-enhanced Raman scattering (SERS)-active substrate. To design and fabricate high-performance SERS-active materials based on organic semiconductors, enhancing the SERS activity and exploring the SERS enhancement mechanisms are important. In this study, a sandwich structure of metal/organic semiconductor/probe molecules was fabricated via a layered self-assembly method. By changing the concentration of the poly(3-hexylthiophene) (P3HT) solution to control the thickness of the P3HT thin film, the dielectric environment surrounding the Ag nanoparticles could be changed, and the localized surface plasmon resonance phenomenon could be effectively controlled. The enhancement of the SERS performance of the Ag/P3HT composite system was studied using mercaptobenzoic acid (MBA) as a probe molecule. Our results showed that the increase in the SERS intensity tended to be stable, and the degree of charge transfer reached the maximum value at a P3HT concentration of 10−5 g/mL. Our findings also suggested that the surface plasmon resonance effect at the Ag/P3HT interface promoted transfer of electrons from the conduction band of Ag/P3HT to the lowest unoccupied molecular orbital of MBA, significantly enhancing the SERS intensity. This study, in which the detection limit for MBA molecules was as low as 10−10 mol/L, confirmed the excellent sensitivity and efficiency of the Ag/P3HT composite as a SERS substrate. The combination of the high electromagnetic field performance of Ag with the efficient charge transfer capability of P3HT significantly improved the SERS activity and detection sensitivity. This study broadens the scope of research on SERS substrates and contributes to the elucidation of the SERS mechanism.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"338 ","pages":"Article 126220"},"PeriodicalIF":4.3,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143838234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Developing an aurone-based colorimetric fluorescent probe for fast cysteine sensing in foods, test strips and biological imaging 开发一种用于食品、试纸和生物成像中快速检测半胱氨酸的荧光比色探针

IF 4.3 2区化学

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Pub Date : 2025-04-11 DOI: 10.1016/j.saa.2025.126226

Xiaoyan Cao , Yichi Zhang , Jialing Hu , Yifan Wei , Yingyue Ding , Yanfei Kang , Chuanqing Ren , Qin Wang

{"title":"Developing an aurone-based colorimetric fluorescent probe for fast cysteine sensing in foods, test strips and biological imaging","authors":"Xiaoyan Cao , Yichi Zhang , Jialing Hu , Yifan Wei , Yingyue Ding , Yanfei Kang , Chuanqing Ren , Qin Wang","doi":"10.1016/j.saa.2025.126226","DOIUrl":"10.1016/j.saa.2025.126226","url":null,"abstract":"<div><div>Cysteine (Cys) is integral to both industrial applications and biological processes. In this study, a novel colorimetric fluorescent sensor APA, defined by its intramolecular charge transfer (ICT) properties, was optimized to effectively discriminate Cys from other structurally similar compounds such as homocysteine (Hcy) and glutathione (GSH). We present the aurone-incorporated fluorescent sensor APA, which features a 4-dimethylaminocinnamaldehyde group conjugated to the aurone scaffold and facilitates selective detection of Cys with a limit of detection (LOD) of 25.7 nM. Compared to previous studies, sensor APA exhibits near-infrared properties, a reduced reaction time of just 2 min, and a significant Stokes shift of 190 nm. Notably, APA has been successfully employed for visual imaging of Cys in test strips and quantitative detection in various food samples in real-time (including garlic, carrot, tomato, onion, green pepper, cauliflower, daikon, lotus root, apple, pear, milk powder, bread, and biscuits). Furthermore, APA has proven effective for colorimetric imaging of both endogenous and exogenous Cys in A549 cells as well as zebrafish and mice models demonstrating its practical biological applications. Overall, our findings highlight the potential of APA as one of the most promising designs for sensing Cys within the food industry and biological systems. Additionally, APA-OH serves as an ideal fluorophore for constructing fluorescence sensors aimed at bioimaging.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"338 ","pages":"Article 126226"},"PeriodicalIF":4.3,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143825996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thiourea-based novel fluorescence chemosensor for selective detection of mercuric ion and its application in bio-imaging 基于硫脲的新型汞离子荧光化学传感器及其在生物成像中的应用

IF 4.3 2区化学

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Pub Date : 2025-04-11 DOI: 10.1016/j.saa.2025.126221

Patitapaban Mohanty , Pragyan P. Dash , Swagatika Mishra , Rubi Behura , P. Behera , Monalisa Mishra , Harekrushna Sahoo , Suban K. Sahoo , Bigyan R. Jali

{"title":"Thiourea-based novel fluorescence chemosensor for selective detection of mercuric ion and its application in bio-imaging","authors":"Patitapaban Mohanty , Pragyan P. Dash , Swagatika Mishra , Rubi Behura , P. Behera , Monalisa Mishra , Harekrushna Sahoo , Suban K. Sahoo , Bigyan R. Jali","doi":"10.1016/j.saa.2025.126221","DOIUrl":"10.1016/j.saa.2025.126221","url":null,"abstract":"<div><div>Sensitive and reliable fluorescence chemosensors for the monitoring of Hg2+ levels are very important for the protection of environment and living systems. Herein, a simple thiourea-based irreversible fluorescence and colorimetric chemosensor L has been devised and characterised by various spectral analysis. Probe L selectively detects Hg2+ ion due to the binding site-signalling strategy, where the pyridine ring serves as the fluorophore unit and the thiourea moiety serves as the coordinating site. The incorporation of Hg2+ ions to a DMSO solution of L shows substantial alterations in the UV–Vis spectrum and fluorescence spectra. This alteration in absorption as well as fluorescence profile refers to the increase in the intra-molecular charge transfer (ICT) and chelation-induced enhanced fluorescence (CHEF) of L-Hg2+ complex. For the Hg2+ ion, the detection limit is reached up to 2.5 × 10−8 M, which is calculated from the IUPAC formula CDL = 3σ/slope. The Job’s plot reveals a 1:1 binding stoichiometry between L and Hg2+. Applying Benesi-Hildebrand equation, the binding constant for the L-Hg2+ complex was estimated as 7.54 × 106 M−1. To validate the mechanism involved in the formation of L-Hg2+ complex, the DFT and TD-DFT calculations were performed in the gas phase. L has been used well to identify Hg2+ ions in soil samples over a wide pH range. The receptor L was also applied for cell imaging study.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"338 ","pages":"Article 126221"},"PeriodicalIF":4.3,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A lysosome-targetable multifunctional fluorescent probe based on intramolecular NH…NH2 hydrogen bonding for detection of hypochlorite and cyanides 基于分子内NH2氢键的溶酶体靶向多功能荧光探针用于检测次氯酸盐和氰化物

IF 4.3 2区化学

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Pub Date : 2025-04-10 DOI: 10.1016/j.saa.2025.126180

Aoran Kan , Yingmei Cao , Qiunan She , Yicong Zhou , Yingming Tan , Jie Yang , Jinwu Yan , Zhenjiang Liu , Chuanxiang Liu

{"title":"A lysosome-targetable multifunctional fluorescent probe based on intramolecular NH…NH2 hydrogen bonding for detection of hypochlorite and cyanides","authors":"Aoran Kan , Yingmei Cao , Qiunan She , Yicong Zhou , Yingming Tan , Jie Yang , Jinwu Yan , Zhenjiang Liu , Chuanxiang Liu","doi":"10.1016/j.saa.2025.126180","DOIUrl":"10.1016/j.saa.2025.126180","url":null,"abstract":"<div><div>The creation of a singular fluorescent probe for the detection of various analytes is crucial for comprehending the interactions among analytes in living cells. This study presents a novel multifunctional fluorescent probe, designated Lyso-Nap-Py, which utilizes distinctive intramolecular NH…NH2 hydrogen bonding for the simultaneous detection of hypochlorite and cyanides within living cells. This probe demonstrates the ability to detect cyanides and hypochlorite, offering advantages including high selectivity, fluorescence turn-off at 638 nm, a low limit of detection, and rapid response times. The Lyso-Nap-Py-immobilized test papers demonstrated notable reversible colorimetric changes observable to the naked eye in response to fluctuations in environmental acidity and basicity, showcasing over four cycles of reversibility. The interactions of Lyso-Nap-Py with cyanides and HClO lead to alterations in emissions within the red channels, yielding specific signal responses to various analytes present in cellular lysosomes. Significantly, through the utilization of this singular probe, we accomplished the imaging of exogenous cyanides and hypochlorite, in addition to endogenous hypochlorite, within living cells and zebrafish. Furthermore, the advantageous features of probes that utilize intramolecular NH…NH2 hydrogen bonding demonstrate considerable promise for their use in cellular imaging within lysosomes.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"338 ","pages":"Article 126180"},"PeriodicalIF":4.3,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143824300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0