Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy最新文献

{"title":"Silver-modified titanium-based MXene as a promising SERS substrate for the characterization of cytotoxic agent cyclophosphamide: Experimental and DFT study","authors":"Shehu Mohammed ,&nbsp;Abdulaziz A. Al-Saadi","doi":"10.1016/j.saa.2025.126055","DOIUrl":"10.1016/j.saa.2025.126055","url":null,"abstract":"<div><div>The emergence of new generations of two-dimensional (2D) nanostructured materials with unique electronic features and efficient charge transfer properties can significantly impact the performance of surface-enhanced Raman scattering (SERS) substrates leading to a fast and reliable spectroanalytical ultra-low concentration detection of bioactive molecules. Due to its short-range charge transfer and superior plasmonic effects, the titanium carbide (Ti₃C₂T_x) family of MXenes has been proven to be a promising candidate for a wide range of optics and sensing-related applications. In this work, the synthesis and characterization of 2D Ti₃C₂T_x MXene layered sheets were carried out. A charge transfer bridging between Ti₃C₂T_x and cyclophosphamide (CPA) drug molecules was successfully established by incorporating silver nanoparticles (AgNPs), resulting in a significantly enhanced Raman response and achieving up to 1 × 10⁻¹⁰ M detection limit of CPA in aqueous media. Spectroscopic and DFT results indicate that the oxazaphosphorine ring, with its heterocyclic nature and multiple electron-rich sites, plays a major role in facilitating the charge transfer mechanism, resulting in a strong analyte-substrate interaction. Given their impressive performance and cost-efficient synthesis protocols, silver-modified metal-based MXene nanocomposites hold great potential for developing a new class of stable SERS substrates, enabling reliable detection in biomedical samples.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"336 ","pages":"Article 126055"},"PeriodicalIF":4.3,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human serum albumin-encapsulated near-infrared hemicyanine photosensitizers for viscosity imaging and enhanced photodynamic therapy","authors":"Wei Chen ,&nbsp;Haoyang Xiao ,&nbsp;Jiaqi Xing ,&nbsp;Jiarao Sun ,&nbsp;Yanfeng Wang ,&nbsp;Jing Shi","doi":"10.1016/j.saa.2025.126060","DOIUrl":"10.1016/j.saa.2025.126060","url":null,"abstract":"<div><div>The research successfully developed a novel dual-function near-infrared photosensitizer, <strong>CyI</strong>, which is encapsulated with human serum albumin (HSA) to form <strong>CyI-HSA</strong> nanocomplex that can simultaneously monitor the viscosity of cancer cell and enhance the efficacy of photodynamic therapy (PDT). <em>In vitro</em> experiments demonstrated that compared with <strong>CyI</strong> alone, <strong>CyI-HSA</strong> has superior water solubility and high photostability, and can effectively prevent aggregation-caused quenching (ACQ) caused by π-π stacking. Additionally, singlet oxygen quantum yield of <strong>CyI-HSA</strong> as high as 27.4 % under 658 nm laser irradiation, indicating significant PDT potential. Cellular experiments further revealed that <strong>CyI-HSA</strong> can monitor intracellular viscosity with high sensitivity, while generating a substantial amount of singlet oxygen, promoting PDT and cell apoptosis. Treatment of HepG-2 cells with 1 µmol/L <strong>CyI-HSA</strong> reduced cell viability by only 13 % (Laser = 100 mW cm⁻²). Therefore, as a kind of nano-photosensitizer integrating diagnostic and therapeutic functions, <strong>CyI-HSA</strong> has a broad prospect in the application of near-infrared hemicyanine photosensitizers in photodynamic therapy.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"336 ","pages":"Article 126060"},"PeriodicalIF":4.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of variable optimization algorithms for PLS regression models of kerosene content in edible oils","authors":"Wangfei Luo ,&nbsp;Jihong Deng ,&nbsp;Hui Jiang ,&nbsp;Quansheng Chen","doi":"10.1016/j.saa.2025.126045","DOIUrl":"10.1016/j.saa.2025.126045","url":null,"abstract":"<div><div>Edible oils may become contaminated with harmful substance residues during transportation, posing a serious threat to food safety and public health. This study utilized Fourier Transform Near-Infrared (FT-NIR) Spectroscopy to extract spectral data for kerosene content in soybean and corn oil. Three feature selection models, Competitive Adaptive Reweighted Sampling (CARS), Bootstrapping Soft Shrinkage (BOSS), and Iteratively Variable Subset Optimization (IVSO), were applied to Savitzky-Golay (SG) preprocessed data. Using the selected features, Partial Least Squares (PLS) regression models were developed. The CARS-optimized PLS model demonstrated superior generalization performance, achieving an RMSEP of 2.4520 <span><math><mrow><mi>m</mi><mi>g</mi><mo>·</mo><msup><mrow><mi>k</mi><mi>g</mi></mrow><mrow><mo>-</mo><mn>1</mn></mrow></msup></mrow></math></span>, a Predictive correlation coefficient (<span><math><msub><mi>R</mi><mi>P</mi></msub></math></span>) of 0.9711, and a relative prediction deviation (RPD) of 4.2562. These results indicate the feasibility of constructing a quantitative model for detecting kerosene content in soybean and corn oil using FT-NIR Spectroscopy with feature selection algorithms.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"336 ","pages":"Article 126045"},"PeriodicalIF":4.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143629429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SERS-based approaches in the investigation of bacterial metabolism, antibiotic resistance, and species identification","authors":"Zhun Nie ,&nbsp;Zhijun Huang ,&nbsp;Zhongying Wu ,&nbsp;Yanlong Xing ,&nbsp;Fabiao Yu ,&nbsp;Rui Wang","doi":"10.1016/j.saa.2025.126051","DOIUrl":"10.1016/j.saa.2025.126051","url":null,"abstract":"<div><div>Surface-enhanced Raman scattering (SERS) is an inelastic scattering phenomenon that occurs when photons interact with substances, providing detailed molecular structure information. It exhibits various advantages including high sensitivity, specificity, and multiple-detection capabilities, which make it particularly effective in bacterial detection and antibiotic resistance research. In this review, we review the recent development of SERS-based approaches in the investigation of bacterial metabolism, antibiotic resistance, and species identification. Although the promising applications have been realized in clinical microbiology and diagnostics, several challenges still limit the further development, including signal variability, the complexity of spectral data interpretation, and the lack of standardized protocols. To overcome these obstacles, more reproducible and standardized methodologies, particularly in nanomaterial design and experimental condition optimization. Furthermore, the integration of SERS with machine learning and artificial intelligence can automate spectral analysis, improving the efficiency and accuracy of bacterial species identification, resistance marker detection, and metabolic monitoring. Combining SERS with other analytical techniques, such as mass spectrometry, fluorescence microscopy, or genomic sequencing, could provide a more comprehensive understanding of bacterial physiology and resistance mechanisms. As SERS technology advances, its applications are expected to extend beyond traditional microbiology to areas like environmental monitoring, food safety, and personalized medicine. In particular, the potential for SERS to be integrated into point-of-care diagnostic devices offers significant promise for enhancing diagnostics in resource-limited settings, providing cost-effective, rapid, and accessible solutions for bacterial infection and resistance detection.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"336 ","pages":"Article 126051"},"PeriodicalIF":4.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143628628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A H2O2 responsive self-activatable fluorescent probe and pro-photosensitizer based on a pyridine-chalcone skeleton","authors":"Yawen Zhang ,&nbsp;Chao Wang ,&nbsp;Jing Zhang ,&nbsp;Aiping Jia ,&nbsp;Yuxia Liu ,&nbsp;Siwei Bi ,&nbsp;Guang Chen","doi":"10.1016/j.saa.2025.126050","DOIUrl":"10.1016/j.saa.2025.126050","url":null,"abstract":"<div><div>Hydrogen peroxide (H₂O₂) is closely associated with various physiological and pathological processes, particularly in tumor microenvironment. It has been designed for the activation and release of fluorescent probes and tumor-related drugs. In this work, we proposed a self-activatable fluorescent probe and pro-photosensitizer (pro-PS) <strong>MN-BP</strong> based on a pyridine-chalcone photosensitizer (PS) <strong>MN</strong> and a H₂O₂ responsive boronate moiety. The endogenous H₂O₂ in tumor cells triggers partial release of PS <strong>MN</strong> from the pro-PS <strong>MN-BP</strong>. Under light irradiation, the generated PS <strong>MN</strong> can produce Reactive oxygen species (ROS) and be partially converted to H₂O₂ to proceed the self-activatable process. The generated H₂O₂ can be used as an activator to accelerate the release of PS <strong>MN</strong>, thus amplifying the effect of photodynamic therapy (PDT) by generating more ROS. In addition, the enhanced fluorescence of pro-PS <strong>MN-BP</strong> can be used for the detection of H₂O₂ and the visualization of photosensitizer, so as to realize the real-time monitoring and regulation of the PDT process.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"336 ","pages":"Article 126050"},"PeriodicalIF":4.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating near-infrared spectroscopy as a rapid and cost-effective method for fatty acid profiling in Senegalese sole (Solea senegalensis)","authors":"Víctor M. Fernández-Cabanás ,&nbsp;Ismael Hachero Cruzado","doi":"10.1016/j.saa.2025.126042","DOIUrl":"10.1016/j.saa.2025.126042","url":null,"abstract":"<div><div>This study evaluates the potential of near-infrared spectroscopy (NIRS) as a rapid and cost-effective technique for estimating the fatty acid profile of Senegalese sole (<em>Solea senegalensis</em>).</div><div>Traditionally, lipid profiling in aquaculture products has relied on gas chromatography (GC), a highly accurate but time-consuming, costly and complex method requiring extensive sample preparation. In contrast, NIRS offers a non-invasive, rapid and accurate alternative for predicting chemical composition. While NIRS has shown success in lipid profiling for fatty fish species, its application to lean fish, such as Senegalese sole, presents challenges due to low lipid concentrations and overlapping spectral signals.</div><div>In this study, Senegalese sole were fed experimental diets varying in marine protein and lipid content. Lipid profiles of 75 tissue samples were analysed using both GC and NIRS, with fatty acid content expressed as percentage of total fatty acids (% TFA) and as µg fatty acid per mg dry tissue (µg FA/mg dry tissue). Calibrations were developed using Modified Partial Least Squares Regression (MPLSR) and the prediction accuracy was assessed using calibration statistics.</div><div>The results showed that dietary lipids significantly influenced the fatty acid composition of Senegalese sole, consistent with previous findings for marine fish. NIRS calibrations were most accurate when fatty acid content was expressed as µg FA/mg dry tissue, giving better predictions than % TFA. The best calibrations were obtained for oleic acid, the dominant fatty acid in Senegalese sole, with an R²cv of 0.83 and a ratio of standard deviation/cross validation error (RPD) of 2.44. Fatty acid group predictions were more accurate for monounsaturated fatty acids (MUFA) than for the other groups, with an R²cv of 0.85 and an RPD of 2.60.</div><div>These results demonstrate the potential of NIRS as a rapid and cost-effective method for fatty acid profiling in Senegalese sole, particularly for the estimation of mono- and polyunsaturated fatty acids (MUFA and PUFA). However, further research is needed to improve the accuracy and robustness of NIRS prediction models. Expanding the calibration dataset to include greater variability in diet, season and cultivation conditions will improve the reliability of the method for wider applications.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"336 ","pages":"Article 126042"},"PeriodicalIF":4.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143628624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of mono-substituents on the polarity-sensitive fluorescent probe properties of pyrene","authors":"Haiyan Wang ,&nbsp;Jing Zhang ,&nbsp;Yong Zhang","doi":"10.1016/j.saa.2025.126049","DOIUrl":"10.1016/j.saa.2025.126049","url":null,"abstract":"<div><div>This study investigates the effects of mono-substituents (i.e., hydroxyl, methyl, amino and nitro groups) on the polarity-sensitive fluorescent probe properties of pyrene (Pyr) using fluorescence, UV–vis, and circular dichroism absorption spectroscopy. The results indicate that the four mono-substituents altered the fluorescence spectral characteristics of Pyr to varying degrees, with the most to least influential order being: nitro, amino, hydroxyl, and methyl. 1-Aminopyrene (1-APyr) and 1-nitropyrene (1-NPyr) are deemed unsuitable for use as polarity-sensitive fluorescent probes due to their limited or absent spectral characteristics. The I₃₈₆/I₄₀₆ and I₃₇₆/I₃₉₆ ratios of 1-HPyr and 1-MPyr decrease as solvents polarity increases, contrasting with the I₃₇₂/I₃₈₄ ratio of Pyr. Thus, 1-hydroxypyrene (1-HPyr) and 1-methylpyrene (1-MPyr) also exhibit polarity-sensitive characteristics similar to Pyr, and their solubility in PBS buffer surpasses that of Pyr at 298 K. Moreover, 1-HPyr and 1-MPyr are practicable for detecting the polarity of human serum albumin (HSA) under simulated physiological conditions. The results underscore the potential of the polarity-sensitive mono-substituents of Pyr in biological applications, particularly in probing protein polarity and conformational changes, and further providing a potential tool for the related research in biochemistry and pathology.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"336 ","pages":"Article 126049"},"PeriodicalIF":4.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PySpectro: A modular 3D printed, machine learning assisted optical device for recognition and quantification of samples","authors":"Cristian Grazioli,&nbsp;Michele Abate,&nbsp;Nicolò Dossi","doi":"10.1016/j.saa.2025.126058","DOIUrl":"10.1016/j.saa.2025.126058","url":null,"abstract":"<div><div>Over the past decade, science and technology have achieved great advancements driven by the synergy between materials and manufacturing processes; coupled with the growth of informatics, which offers powerful tools to process and interpret data, new analytical devices have been developed. This work describes a modular 3D printed instrument that utilizes the AS7262 light sensor coupled with a LED to perform absorbance and reflectance measurements. The mode of operation can be switched by conveniently attaching different 3D printed parts. An Arduino Nano is used for operating the electronics, and a python-based software is employed for data handling. The device, beside spectra acquisition, allows rapid identification and quantification of samples through a database and machine learning (ML) algorithms. A recursive methodology for regression specifically designed allowed sample quantification in a range spanning around 2.5 orders of magnitude with errors generally below 10%. PySpectro was used on homogeneous solution and on PADs (Paper-based Analytical Devices) for food dyes and phosphomolybdic assay for phosphate. The device may find applications in any colorimetric detection also outside the laboratory environment and can be a time-saving tool for fast preliminary determinations or educational purposes.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"336 ","pages":"Article 126058"},"PeriodicalIF":4.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Luminescence depletion imaging of SrAl2O4:Eu2+, Dy3+ using solid state laser in dark field microscopy","authors":"Fatemeh Dehnavi,&nbsp;Nader Shokoufi","doi":"10.1016/j.saa.2025.126052","DOIUrl":"10.1016/j.saa.2025.126052","url":null,"abstract":"<div><div>Numerous studies have been conducted on the SrAl₂O₄:Eu²⁺, Dy³⁺ phosphor (SAOED). One feature frequently ignored is that the radiation from the laser in this phosphor turns off the luminescence emission, which may impact these materials’ potential applications. We studied the photoluminescence (PL) emission behavior of SrAl₂O₄:Eu²⁺, Dy³⁺ phosphor under laser irradiation. The results show that lasers deplete the luminescence. Experimental results showed that applying of 532 nm and 660 nm lasers resulted in a depletion in emission intensity. This depletion was confirmed by histograms and 3D intensity plots, which revealed a shift toward lower intensity values. Additionally, the phosphor coated with SiO₂ showed successful encapsulation, was validated by SEM and EDX analysis, and the photoluminescence spectra showed a slight decrease in emission intensity due to the silica coating. The purpose of this study is to implement a method for suppressing luminescence emission using a laser and apply it to microscopic applications and chemical analysis. This method involves laser-induced depletion of sample luminescence emission and dark-field imaging. The combination of spectroscopic, microscopic, and image processing methods allows for sample observation and analysis. The purpose of this project is integrating these techniques to provide an efficient approach to studying and analyzing samples at a microscopic level.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"336 ","pages":"Article 126052"},"PeriodicalIF":4.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143636839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-wavelength emission nitrogen-doped carbon dots as fluorescent nanosensing platform for the detection of ascorbic acid and their application in bioimaging tracking","authors":"Zhi-Li Jia ,&nbsp;Kun-Peng Lin ,&nbsp;Yi Zhang ,&nbsp;Pei-De Zhu ,&nbsp;Zhen-Dong Zhu ,&nbsp;Xu-Le Wang ,&nbsp;Qing-Yan Zhu ,&nbsp;Hang-Kai Shen ,&nbsp;Zi-Xuan Guo ,&nbsp;Zi-Ying Wang ,&nbsp;Xue-Lin Zhao ,&nbsp;Meng Xu","doi":"10.1016/j.saa.2025.126028","DOIUrl":"10.1016/j.saa.2025.126028","url":null,"abstract":"<div><div>Vitamins are indispensable active components of the human body, and their abnormal levels are often closely related to various diseases. Therefore, searching for ultra-sensitive and accurate vitamin detection strategies is essential and significant for clinical examination and diagnosis. In this paper, multi-wavelength emission fluorescent nitrogen-doped carbon dots (N-doped CDs) were synthesized by a one-step solvothermal method using four-leaf green fluorescent extract, O-phenylenediamine, and β-cyclodextrin as the raw materials, and N, N-dimethylformamide as the solvent. The CDs can achieve controllable fluorescence changes with multi-wavelength emission at different excitation wavelengths and exhibit good photoluminescence optical properties. In addition, the fluorescence emission peak intensities of the N-doped CDs at 400, and 470 nm excitation wavelengths decreased with increased AA content. They showed good linearity in the 0.6–1.4, and 0.1–0.5 μM ranges, with detection limit coefficients of 0.12, and 0.14 μM, respectively. Moreover, due to their excellent photostability and good biocompatibility, N-doped CDs have been successfully applied to the bioimaging and biosensing of exogenous AA in 4T1 cells, as well as in vivo imaging tracking of Kunming (KM) mice.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"336 ","pages":"Article 126028"},"PeriodicalIF":4.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143628625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}