Marmara Medical Journal最新文献_第9页

Demographic and microbiological characteristics of tuberculous lymphadenitis and other extrapulmonary tuberculosis cases 结核性淋巴结炎和其他肺外结核病例的人口统计学和微生物学特征

IF 0.2

Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1191093

L. N. Altunal, Buket Erturk Sengel, A. Ozel, M. Aydın, A. Kadanalı

{"title":"Demographic and microbiological characteristics of tuberculous lymphadenitis and other extrapulmonary tuberculosis cases","authors":"L. N. Altunal, Buket Erturk Sengel, A. Ozel, M. Aydın, A. Kadanalı","doi":"10.5472/marumj.1191093","DOIUrl":"https://doi.org/10.5472/marumj.1191093","url":null,"abstract":"Objective: Tuberculosis (TB) is a significant public health problem that remains important worldwide. This study aimed to examine \u0000the demographic characteristics and clinical features of patients with extrapulmonary tuberculosis (EPTB) and also identify the \u0000comorbidities of EPTB. Our secondary aim was to compare tuberculous lymphadenitis (TBL) with other forms of EPTB. \u0000Patients and Methods: This single-center, retrospective, observational study was conducted on patients diagnosed with EPTB in a \u0000training hospital in Turkey between January 1, 2011 and December 31, 2020. The demographic characteristics and clinical features of \u0000the patients were examined. TBL cases were compared with other forms of EPTB cases. \u0000Results: The most common clinical form was TBL. Fever, night sweats, and accelerated erythrocyte sedimentation rate were \u0000significantly more common in the other forms of the EPTB group compared to TBL. The rate of tuberculin skin test positivity was \u0000significantly higher in patients with TBL. The complication rate was 3%, and mortality rate was 4% among all patients. \u0000Conclusions: Extrapulmonary tuberculosis should be considered in the differential diagnosis by evaluating the medical history of \u0000patients who present with organ-specific symptoms, especially in TB endemic countries. The clinic may differ according to the organ \u0000involvement. TBL may be seen with milder symptoms compared to other clinical forms.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":"9 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41292900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the efficacy of several sclerosing agents for pleurodesis in rats 几种硬化剂治疗大鼠胸膜穿孔术的疗效评价

IF 0.2

Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1191101

C. Balta, M. Kuzucuoğlu, Figen Aslan, Ali Cem Yekdeş

{"title":"Evaluation of the efficacy of several sclerosing agents for pleurodesis in rats","authors":"C. Balta, M. Kuzucuoğlu, Figen Aslan, Ali Cem Yekdeş","doi":"10.5472/marumj.1191101","DOIUrl":"https://doi.org/10.5472/marumj.1191101","url":null,"abstract":"Objective: This study aims to evaluate the efficiencies and effects of different sclerosing agents. \u0000Materials and Methods: Thirty-five female Wistar-albino rats were included in this study and divided into five groups randomly. \u0000Isotonic saline (group 1), iodopovidone (group 2), rifamycin (group 3), autologous blood (group 4), talc (group 5) were given into \u0000intrapleural space. On postoperative 28th day, ipsilateral and contralateral pleural and parenchymal fibrosis and inflammation were \u0000evaluated. \u0000Results: There were statistically differences between control and other groups on macroscopically pleural fibrosis examination \u0000(p=0.004, p=0.001, p=0.001, p=0.000, respectively). Microscopically pleural fibrosis were determined in all groups when compared \u0000to control group (p=0.023, p=0.023, p=0.035, p=0.001, respectively). There were no significant differences between sclerosing agent \u0000groups (p>0.05). Significant differences were observed according to microscopic pleural inflammation evaluation between talc group \u0000and other groups. There was superiority in talc group according to intraparenchymal inflammation grade compared to other groups \u0000(p=0.010, p=0.042, p=0.030, respectively). Macroscopically, fibrosis and microscopically, inflammation were significantly observed \u0000between talc and other groups in the contralateral pleura (p = 0.037and p=0.009, respectively). \u0000Conclusion: Iodopovidone, autologous blood, talc, and rifamycin can be used as effective pleurodesis agents. However, we found that \u0000rifamycin and autologous blood are safer as effective pleurodesis agents. We think that these two agents can be used in patients with \u0000secondary lung diseases due to their less intraparenchymal inflammation rates. It may be advantageous to prefer other sclerosing \u0000agents which has lower costs and less side effects comparing to talc.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70885480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of social support, depression, and illness perception on treatment adherence in patients with multiple sclerosis 社会支持、抑郁和疾病感知对多发性硬化症患者治疗依从性的影响

IF 0.2

Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1192560

Derya Gi̇rgi̇n, Z. Tosun, N. Turgut, S. Guler

引用次数: 0

Relationship between disease severity, perceived stress, and depression in patients with seborrheic dermatitis 脂溢性皮炎患者的疾病严重程度、感知压力和抑郁之间的关系

IF 0.2

Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1195298

Esra Saraç

{"title":"Relationship between disease severity, perceived stress, and depression in patients with seborrheic dermatitis","authors":"Esra Saraç","doi":"10.5472/marumj.1195298","DOIUrl":"https://doi.org/10.5472/marumj.1195298","url":null,"abstract":"Objective: A significant proportion of patients with seborrheic dermatitis state that disease attacks are triggered by psychological \u0000stress and disease severity increases during stressful times. This study aimed to determine the relationship between disease severity \u0000and perceived stress and depression levels in patients with seborrheic dermatitis. \u0000Patients and Methods: The patients’ demographic characteristics, medical history, and Seborrheic Dermatitis Area Severity Index \u0000(SDASI), Perceived Stress Scale (PSS), and Beck Depression Inventory (BDI) scores were recorded, and the relationship between \u0000disease severity and the scale scores were statistically analyzed by comparing disease severity groups and using correlation analyses. \u0000Results: The study included 120 patients with seborrheic dermatitis. The mean age of the patients was 29.5±8.2 years, and the female/ \u0000male ratio was 49/71. According to disease severity, 66 (55%) patients were classified as mild, 30(25%) moderate, and 24 (20%) as \u0000severe seborrheic dermatitis. When the scale scores were evaluated, a significant positive correlation was found between SDASI and \u0000PSS (r=0.767, p","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49643914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Partial healing effects of St. John’s wort oil on the rat excisional wound model 圣约翰草油对大鼠切除性创伤模型的部分愈合作用

IF 0.2

Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1186858

Ayse Nilhan Aksu, T. Bilgiç, C. Kayhan, Zumrut Mine Isik Saglam, N. Caf

{"title":"Partial healing effects of St. John’s wort oil on the rat excisional wound model","authors":"Ayse Nilhan Aksu, T. Bilgiç, C. Kayhan, Zumrut Mine Isik Saglam, N. Caf","doi":"10.5472/marumj.1186858","DOIUrl":"https://doi.org/10.5472/marumj.1186858","url":null,"abstract":"Objective: St. John’s wort (SJW) oil (Hypericum perforatum) has been used for its immunomodulatory and anti-inflammatory effects. \u0000Several studies have shown the efficacy of SJW on wound healing. The aim of this study is to assess the effectiveness of SJW using a \u0000combination of biochemical, histopathological and laser Doppler evaluations. \u0000Materials and Methods: Sixteen young Wistar albino rats were used as case and control groups (having 8 in each group). After \u0000anesthesia protocol, 6 mm punch biopsy was taken from six separate sites on the rats’ dorsal skin. Three wounds were stitched (closed \u0000wounds); three wounds were left as they were (open wounds). SJW oil was administered topically to case group once a day for 14 days. \u0000Controls did not receive any treatment. \u0000Results: There was no statistical difference in blood perfusion between the groups. No statistical difference was present between the \u0000groups in GPx (glutathione peroxidase)values. Rat MDA (malonyldialdehyde) values were higher in the case group compared to the \u0000control group. SJW oil was found to be beneficial and effective within some histological parameters. \u0000Conclusion: SJW may be an effective salve within some parameters. Nevertheless, this judgment is uncertain due to the low sample \u0000size. We encourage further studies on this promising natural medicine.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45702202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of tocilizumab therapy in severe COVID-19 pneumonia patients and determination of the prognostic factors affecting 30 days mortality 托珠单抗治疗COVID-19重症肺炎患者的疗效及影响30天死亡率的预后因素测定

IF 0.2

Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1191126

L. Delen, U. Kasapoğlu, Abdullah Gok, O. Cagasar, B. Tetik, E. Oksuz

{"title":"Efficacy of tocilizumab therapy in severe COVID-19 pneumonia patients and determination of the prognostic factors affecting 30 days mortality","authors":"L. Delen, U. Kasapoğlu, Abdullah Gok, O. Cagasar, B. Tetik, E. Oksuz","doi":"10.5472/marumj.1191126","DOIUrl":"https://doi.org/10.5472/marumj.1191126","url":null,"abstract":"Objective: In coronavirus disease – 19 (COVID-19) patients, cytokine storm develops due to the increase of pro-inflammatory \u0000cytokines. Tocilizumab (TCZ), has been used in the treatment of COVID-19 patients and successful results have been obtained. The \u0000aim of this study was to determine the efficacy of TCZ and also investigate the prognostic factors affecting the success of treatment \u0000and mortality in COVID-19 patients treated with TCZ. \u0000Patients and Methods: Between March 2020 and August 2021, a total of 326 confirmed severe COVID-19 pneumonia patients, treated \u0000in the intensive care unit, were included in the study. \u0000Results: The mean age of the patients was 63.02±11.58 years, and 203 (62.3%) of the patients were male. Patients treated with TCZ \u0000therapy had a longer survival time compared with the standard therapy (p=0.012). It was found that type of respiratory support \u0000(HR:2.19, CI:1.10-4.36, p=0.025) and hyperlactatemia on the day of TCZ therapy admission (HR:2.93 CI:1.53-5.64, p=0.001) were the \u0000significant and independent prognostic factors of survival in severe COVID-19 pneumonia patients treated with TCZ. \u0000Conclusion: Tocilizumab therapy improved 30-days survival in critically ill COVID-19 pneumonia patients. Also, among the patients \u0000treated with TCZ, types of respiratory support and hyperlactatemia on the day of TCZ admission were the independent prognostic \u0000factors.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48643577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Viper bite in an urban area : A case report 城市毒蛇咬伤一例报告

IF 0.2

Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1191161

Hasan Demir, Aykut Ozkan, Melis Efeoglu Sacak, Nurseli Bayram, Boran ISIN UNAL, Cansu Tiris, Murat Gol, A. Denizbasi

引用次数: 0

Prevalence of cervical high-risk human papillomavirus and cytological abnormalities in elderly Turkish women 土耳其老年妇女宫颈高危型人乳头瘤病毒的患病率和细胞学异常

IF 0.2

Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1186851

C. Yalçınkaya

{"title":"Prevalence of cervical high-risk human papillomavirus and cytological abnormalities in elderly Turkish women","authors":"C. Yalçınkaya","doi":"10.5472/marumj.1186851","DOIUrl":"https://doi.org/10.5472/marumj.1186851","url":null,"abstract":"Objective: Cervical cancer (CC) screening ends at the age of 65 in Turkey, as in many countries. However, about a quarter of CCs \u0000occurs in women over the age of 65. Persistent high-risk human papillomavirus(HR-HPV) infection is the most important factor \u0000leading to CC. In this study, we aimed to investigate the prevalence of cervical HR-HPV and cytological abnormalities in Turkish \u0000women aged 65 and over. \u0000Patients and Methods: A total of 467 women between the ages of 66-84 who were referred to the gynecology outpatient clinics for any \u0000reason between January 2010 and December 2021 were included in the study. Pap smears (liquid-based) of patients were screened for \u0000HPV DNA typing using the COBAS test system and evaluated cytopathologicaly. \u0000Results: The mean age of women was 72.4 years. The prevalence of HR – HPV was 5.1% (n = 24), HPV-16 and HPV-18 subtypes \u0000constituted 58.4% of all positive cases. The rate of cervical HR-HPV and cytological abnormalities were not statistically different \u0000between age groups. Of the women with a positive HR-HPV test in Pap smear, cytological abnormalities were found to be more \u0000frequent when compared to HR-HPV negatives (95.8%, n=23 vs 4.3%, n=19, p","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47062921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unilocular and multilocular thymic cysts: A study on the possible histomorphological and/or clinical differences 单房和多房胸腺囊肿：可能的组织形态学和/或临床差异的研究

IF 0.2

Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1192193

E. Bozkurtlar

引用次数: 0

Investigation of the lawsuits regarding down syndrome 唐氏综合症相关诉讼案件调查

IF 0.2

Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1186743

H. Kaymakçalan

{"title":"Investigation of the lawsuits regarding down syndrome","authors":"H. Kaymakçalan","doi":"10.5472/marumj.1186743","DOIUrl":"https://doi.org/10.5472/marumj.1186743","url":null,"abstract":"Objective: To examine the number of cases filed about Down syndrome in terms of its numbers, causes and consequences, to provide \u0000an overview of what doctors should pay attention to when informing and consulting patients and during follow-up and recommend \u0000solutions for decreasing the number of malpractice cases. (Discussing the legal aspect of the decisions is beyond the scope of this \u0000research.) \u0000Materials and Methods: ‘Down’, ‘Down sendromu’ ‘Down’s, ‘trizomi 21 ‘, ‘trisomi 21’ and ‘trisomy 21’ was written to ‘ https:// \u0000karararama.yargitay.gov.tr/ ‘ and ‘https://karararama.danistay.gov.tr/’ web addresses search engines and the data was examined with \u0000Microsoft Excel or with R version 4.0.5 ( 2021-03-31) for bias and frequency table was used and the results were examined. \u0000Results: A total of 53 cases were found. 49 supreme court and 4 Council of State court decisions are found. The cases are from \u000027.10.2009 to 13.10.2021.. \u0000Conclusion: A total of 39 different Down syndrome cases were examined, as 6 of the 53 cases were related to the same cases and 8 \u0000of them were cases not related to Down syndrome. 28 cases are “doctor negligence”, 5 are “reckless killing”, 1 “material mixing in the \u0000genetic center”, 1 “unauthorized use of the child’s photo”, 1 “stealing money from the child”, 1 “intentionally injuring the child”, 1 \u0000‘inheritance request for the child’ and 1 on ‘guardianship’.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42031558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0