Marmara Medical Journal最新文献_第8页

Healing effects of L-carnitine on experimental colon anastomosis wound L-肉碱对实验性结肠吻合口伤口的愈合作用

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Marmara Medical Journal Pub Date : 2023-01-16 DOI: 10.5472/marumj.1307971

Emel Kandaş, M. Edremitlioğlu, U. Demir, G. Erbil, M. H. Sehitoglu

引用次数: 0

Incidental findings detected on magnetic resonance imaging scans of the cervical, thoracic and lumbar spine of patients prediagnosed with discopathy 在预诊断为椎间盘突出症的患者的颈椎、胸椎和腰椎的磁共振成像扫描中发现的偶然发现

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Marmara Medical Journal Pub Date : 2022-12-22 DOI: 10.5472/marumj.1307952

S. Kaya, Hakan Hatirli, Muhammed Azad Şahi̇n, Samet Genez, M. Okçu

{"title":"Incidental findings detected on magnetic resonance imaging scans of the cervical, thoracic and lumbar spine of patients prediagnosed with discopathy","authors":"S. Kaya, Hakan Hatirli, Muhammed Azad Şahi̇n, Samet Genez, M. Okçu","doi":"10.5472/marumj.1307952","DOIUrl":"https://doi.org/10.5472/marumj.1307952","url":null,"abstract":"Objective: To determine the frequency and types of incidental findings on magnetic resonance imaging (MRI) scans of the cervical, \u0000thoracic, and lumbar spine in patients with intervertebral discopathy. \u0000Patients and Methods: This retrospective study included 1000 patients (513 females and 487 males, with a mean age of 50.5 years) \u0000with clinically suspected intervertebral discopathy who underwent MRI. Any abnormal findings and congenital anomalies/anatomical \u0000variations unrelated to the primary complaint were referred to as incidental findings. Frequency distributions of the assessed imaging \u0000characteristics were calculated. \u0000Results: Of the 1000 patients, 192 (19.2%) patients were presented with incidental findings. The positive findings in the thoracic spine \u0000(26%) were higher than those in the lumbar (19.8%) and cervical spine (13.7%). The study found vertebral haemangioma to be the \u0000most common finding, followed by Schmorl’s nodes in the thoracic and lumbar spine. Thyroid nodules constituted the most common \u0000finding in the cervical spine, followed by vertebral haemangioma. Renal cysts in the thoracic and lumbar spine and thyroid nodules in \u0000the cervical spine were the most frequent extraspinal findings. \u0000Conclusion: Incidental findings are commonly detected during MRI examination of intervertebral discs, and most are benign findings. \u0000However, incidental findings including clinically essential findings can alter the patient’s treatment or affect the patient’s life. Therefore, \u0000it is crucial to systematically evaluate MRIs without focusing solely on the spine and report incidental findings detected on MRI.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41548184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effects of alpha-lipoic acid (ALA) on the urinary bladder injury in rats exposed to chronic stress: A histochemical study α-硫辛酸对慢性应激大鼠膀胱损伤影响的组织化学研究

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Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1191211

Necati Yurdakul, Esra CIKLER1,3, H. Toklu, S. Şirvancı

{"title":"The effects of alpha-lipoic acid (ALA) on the urinary bladder injury in rats exposed to chronic stress: A histochemical study","authors":"Necati Yurdakul, Esra CIKLER1,3, H. Toklu, S. Şirvancı","doi":"10.5472/marumj.1191211","DOIUrl":"https://doi.org/10.5472/marumj.1191211","url":null,"abstract":"Objective: In the present study, we aimed to investigate the morphological and biochemical effects of alpha-lipoic acid (ALA) on \u0000bladder injury caused by water avoidance stress (WAS) and to show its effect on the number of degranulated mast cells, which \u0000increase after stress. \u0000Materials and Methods: Wistar albino rats were subjected to WAS and the animals in the treatment group were injected ALA. After \u0000the urinary bladder tissues were subjected to routine tissue processing, hematoxylin-eosin staining and periodic acid-Schiff reaction \u0000were applied to observe general morphology and acidic toluidine blue method to investigate mast cells. Biochemical assessments \u0000of malondialdehyde (MDA) and glutathione (GSH) were also obtained. Transmission electron microscope was used for the \u0000ultrastructural, and scanning electron microscope for the topographical analyses. \u0000Results: The experiments showed that chronic stress caused injury in the bladder, increased degranulated and total number of mast \u0000cells and decreased GSH and increased MDA levels. ALA treatment after WAS ameliorated bladder injury in most areas, decreased \u0000degranulated and total mast cell number and increased GSH and decreased MDA levels. \u0000Conclusion: It was concluded that ALA can be a useful agent in the treatment of interstitial cystitis.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45311085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thyroid diseases in patients with active endogenous Cushing’s syndrome 活动性内源性库欣综合征患者的甲状腺疾病

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Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1186788

T. Toptas, Kubra Bercem Kahraman, Zilan Topcu, H. Bostan, P. Kadıoğlu

{"title":"Thyroid diseases in patients with active endogenous Cushing’s syndrome","authors":"T. Toptas, Kubra Bercem Kahraman, Zilan Topcu, H. Bostan, P. Kadıoğlu","doi":"10.5472/marumj.1186788","DOIUrl":"https://doi.org/10.5472/marumj.1186788","url":null,"abstract":"Objective: Data about the impact of Cushing’s syndrome (CS) on thyroid is scarce. We aimed to identify the prevalence of thyroid \u0000diseases in patients with CS. \u0000Patients and Methods: Nineteen patients with CS and 40 healthy participants were included in the study. All patients were tested \u0000for free tri-iodothyronine (fT3), free thyroxine (fT4), thyroid-stimulating hormone (TSH), anti-thyroglobulin (anti-Tg), and antithyroid \u0000peroxidase (anti-TPO) levels, and thyroid ultrasonography (US). \u0000Results: Overt hypothyroidism, subclinical hypothyroidism, and subclinical hyperthyroidism was evident in 5.3%, 5.3%, and 21.1% of \u0000patients with CS; and 2.5%, 7.5%, and 15% of healthy subjects, respectively. fT3 and fT4 levels were lower in patients with CS. None \u0000of the patients with CS and 27.5% of the control group had autoimmune thyroid disease (AITD), which was demonstrated by both \u0000US findings and anti-TPO positivity (P=0.01). Frequency of thyroid nodule was 52.6% and 52.5% in patients with CS and controls, \u0000respectively (P=0.99). \u0000Conclusion: The prevalence of thyroid dysfunction, nodular thyroid disease, and goiter is comparable to healthy population. However, \u0000AITD is less prevalent among patients with CS. Although, hypercortisolism has an impact on hypothalamic-hypophyseal-thyroid \u0000axis, its clinical implication does not seem to be significant.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44868532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of the changes in pulmonary artery diameters with clinical outcomes in hospitalized patients with COVID-19 infection: A crosssectional study COVID-19感染住院患者肺动脉直径变化与临床结局的关系:一项横断面研究

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Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1195539

Aybuke Selcuk, C. Ilgın, S. Karakurt

引用次数: 1

Comparison of respiratory morbidity in late preterm infants and intrauterine growth retarded infants at school-age 学龄期晚期早产儿与宫内发育迟缓儿呼吸道疾病的比较

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Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1195309

M. Us, U. Vatansever, R. Duran, B. Acunaş

{"title":"Comparison of respiratory morbidity in late preterm infants and intrauterine growth retarded infants at school-age","authors":"M. Us, U. Vatansever, R. Duran, B. Acunaş","doi":"10.5472/marumj.1195309","DOIUrl":"https://doi.org/10.5472/marumj.1195309","url":null,"abstract":"Objective: We aimed to determine respiratory morbidity of late preterm infants versus infants with intrauterine growth retardation \u0000(IUGR) at school-age. \u0000Patients and Methods: Late preterm appropriate for gestational age (AGA) infants (34-36, 6/7 weeks) (Group 1), IUGR infants (Group \u00002), extremely preterm AGA (Group 3) and term AGA infants (Group 4) born between 2004 and 2008 were included in this casecontrol \u0000study and assessed for respiratory morbidity at school-age. We evaluated the impact of late preterm compared with IUGR and \u0000term gestation on respiratory morbidity by using validated American Thoracic Society – Division of Lung Diseases (ATS-DLD-78-C) \u0000and the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaires. Questionnaires on wheezing, infectious \u0000respiratory morbidity, and physician-diagnosed asthma panels were constituted and groups were compared. \u0000Results: A total of 160 patients were enrolled in the study and 97 (60.6%) of them were boys. Respiratory morbidities at schoolage \u0000were found to be significantly higher in both late preterm and IUGR groups when compared to term controls. Each weekly \u0000increase in gestational age reduced the risk for wheezing episodes (OR perGW:0.82,95%CI:0.71-0.97, p:0.02). Regarding \u0000infectious respiratory morbidities, there was a significant increase when the number of people living at home increased (OR \u0000perperson:1.79,95%CI:1.12-2.87, p:0.01), and a decrease in female gender (OR:0.41,95%CI:0.17-0.99, p:0.04) and in the week of \u0000gestation (OR perGW:0.84,95%CI:0.71-1.00, p:0.04). Atopic dermatitis (OR:5.26,95%CI:1.57-17.69, p","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47058368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systemic immune-inflammation index and other inflammatory parameters in patients receiving biological or targeted synthetic DMARDs for inflammatory rheumatic disease 接受生物或靶向合成dmard治疗炎性风湿病患者的全身免疫炎症指数和其他炎症参数

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Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1186732

H. H. Gezer, O. Pehlivan

引用次数: 0

Assessment of the factors affecting the loss of workforce in patients with traumatic hand injury 影响手外伤患者劳动力流失因素的评估

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Marmara Medical Journal Pub Date : 2022-10-31 DOI: 10.5472/marumj.1186710

Kardelen Gençer Atalay, Merve Demirci, Ozgur Baysal, Canan Şanal Toprak

引用次数: 0

Parvovirus-induced autoimmune hepatitis: First case in the literature 细小病毒引起的自身免疫性肝炎:文献中的首例