Universities' Journal of Phytochemistry and Ayurvedic Heights最新文献

Cyperus scariosus rhizome essential oil - physio-chemical characteristics and anxiolytic potential 香柏根精油理化特性及抗焦虑潜能

Universities' Journal of Phytochemistry and Ayurvedic Heights Pub Date : 2023-06-24 DOI: 10.51129/ujpah-2022-34-1(5)

V. Parcha, Pankaj Bhandari

{"title":"Cyperus scariosus rhizome essential oil - physio-chemical characteristics and anxiolytic potential","authors":"V. Parcha, Pankaj Bhandari","doi":"10.51129/ujpah-2022-34-1(5)","DOIUrl":"https://doi.org/10.51129/ujpah-2022-34-1(5)","url":null,"abstract":"Essential oils are important plant products that often have a complicated composition made up of the volatile plant components. Numerous biological actions are reportedly connected to essential oils, and a new class of aromaceuticals is being developed. The market for essential oils has increased since they are used to cure these types of ailments as a result of the emergence of various mental issues due to changing living standards, such as depression, anxiety, sleeplessness, and stress. Studies on animal models have shown that the mode of action of essential oils, which cause physiological changes in the brain, involves a number of neurotransmitter systems. Despite mounting proof that essential oils have quantifiable effects on animal behavior. Therefore the current study is proposed to investigate the physical and chemical characteristics of the essential oil obtained from the rhizome of Cyperus scariosus and assess its anxiolytic effects on the central nervous system in rodent models. Hydro distillation was used to extract the essential oil from the rhizomes of the plant. Total yield, physical properties like viscosity, specific gravity, refractive index, acidity, saponification, iodine no, etc were examined .Further to determine its impact on the central nervous system in a rodent model studies were performed at a dose level of 250 mg/kg body weight and compared to the benchmark medication caffeine @100 mg/kg body weight. The essential oil has a sustainably stimulating impact on the central nervous system in a proportion of 88% compared to caffeine's 68%, according to CNS locomotors count and physicochemical features that were in good accordance with literature value.","PeriodicalId":432227,"journal":{"name":"Universities' Journal of Phytochemistry and Ayurvedic Heights","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128525357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification and quantification of cinnamic acid derivatives in Cichorium intybus seed and its extract by High- Performance Liquid Chromatography with Diode-Array Detector (HPLC-DAD) and Electrospray Ionization Mass Spectrophotometry (LC-MS/MS) 高效液相色谱-二极管阵列检测器(HPLC-DAD)和电喷雾电离质谱法(LC-MS/MS)鉴定和定量菊科种子及其提取物中肉桂酸衍生物

Universities' Journal of Phytochemistry and Ayurvedic Heights Pub Date : 2023-06-24 DOI: 10.51129/ujpah-2022-34-1(1)

N. Prakash, D. Reddy, R. Sundaram, U. Babu, L. Sharath, I. Bindu, Chennu Surendra

{"title":"Identification and quantification of cinnamic acid derivatives in Cichorium intybus seed and its extract by High- Performance Liquid Chromatography with Diode-Array Detector (HPLC-DAD) and Electrospray Ionization Mass Spectrophotometry (LC-MS/MS)","authors":"N. Prakash, D. Reddy, R. Sundaram, U. Babu, L. Sharath, I. Bindu, Chennu Surendra","doi":"10.51129/ujpah-2022-34-1(1)","DOIUrl":"https://doi.org/10.51129/ujpah-2022-34-1(1)","url":null,"abstract":"A sensitive method coupling high-performance liquid chromatography (HPLC) with diode –array detector (DAD) and electrospray ionization mass spectrometry (MS) was optimized for separation, identification, and quantification of cinnamic acid derivatives in Cichorium intybus seed and its extract. Cinnamic acid derivatives such as chlorogenic acid, caffeic acid and Chicoric acid were quantified using respective standards. Apart from 4-o-Caffeoylqunic acid, other cinnamic acid derivative such as 3-o-caffeoylquinic acid was also identified and quantified by UV and MS/MS spectra and calculated as total caffeoylquinic acids using 4-o-caffeoylqunic acid as standard in the seed and its extract. Other cinnamic acid derivatives such as 1,3-dicaffeoylqunic acid, 1,4-dicaffeoylquinic acid, 3,5-dicaffeoylquinic acid, 3, 4-dicaffeoylquinic acid, dicaffeoylquinic acid-1 and dicaffeoylquinic acid-2 (two unknown) were identified and quantified by UV and MS spectra and calculated as total dicaffeoylquinic acids using chlorogenic acid standard in the seed and its extract. The total cinnamic acids were quantified by calculating the sum of chlorogenic acid, caffeic acid, chicoric acid, total caffeoylquinic acids(4-o-caffeoylquinic acid and 3-o-caffeoylqunic acid) and total dicaffeoyl-quinic acids(1,3-dicaffeoylqunic acid, 1,4-dicaffeoylquinic acid, 3,5-dicaffeoyl-quinic acid, 3, 4-dicaffeoylquinic acid, dicaffeoylquinic acid-1 and dicaffeoyl-quinic acid-2). The Phytochemical screening of C. intybus seed and its extract revealed that this plant is a rich source of cinnamic acid derivatives so, these markers (cinnamic acid derivatives) can used for routine quality control of Cichorium intybus seed and its extract.","PeriodicalId":432227,"journal":{"name":"Universities' Journal of Phytochemistry and Ayurvedic Heights","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125426238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extraction and dyeing of eco-friendly natural dye from Lodh bark on wool fabrics and optimization of procedure for dyeing using herbal mordants 羊毛织物上环保天然染料的提取染色及草本媒染剂染色工艺的优化

Universities' Journal of Phytochemistry and Ayurvedic Heights Pub Date : 2023-06-24 DOI: 10.51129/ujpah-2022-34-1(4)

Naveen Kumar, Shyam Vir Singh, M. Purohit

引用次数: 0

Primary and secondary metabolites identification in Hamelia patens leaves 哈梅内伊叶片初级和次级代谢产物的鉴定

Universities' Journal of Phytochemistry and Ayurvedic Heights Pub Date : 2023-06-24 DOI: 10.51129/ujpah-2022-34-1(7)

S. Tyagi, Ashok Kumar, A. Garg, I. P. Pandey

引用次数: 0

Formulation and evaluation of Chocolate Lozenges for cessation of smoking 戒烟用巧克力含片的配方及评价

Universities' Journal of Phytochemistry and Ayurvedic Heights Pub Date : 2023-06-24 DOI: 10.51129/ujpah-2022-34-1(9)

D. Raina, Manish Kumar, Banti Rana, Prachi Mall

引用次数: 0

Antibacterial activity of stem bark extract of traditionally used Terminalia bellirica (Gaerth.) Roxb. 传统药材白莲茎皮提取物的抑菌活性研究Roxb。

Universities' Journal of Phytochemistry and Ayurvedic Heights Pub Date : 2023-06-24 DOI: 10.51129/ujpah-2022-34-1(3)

Shyam Vir Singh, Naveen Kumar, Ankita Singh, J. S. Jangwan

{"title":"Antibacterial activity of stem bark extract of traditionally used Terminalia bellirica (Gaerth.) Roxb.","authors":"Shyam Vir Singh, Naveen Kumar, Ankita Singh, J. S. Jangwan","doi":"10.51129/ujpah-2022-34-1(3)","DOIUrl":"https://doi.org/10.51129/ujpah-2022-34-1(3)","url":null,"abstract":"Medicinal Plants have been practised for hundreds of centuries by tribes all over the world. From the earliest times until the end of nineteenth century plants are still the common source of medicinal treatment yet. Using natural, plant-derived medicines that are “healthier” than prescription drugs derived from synthesized products is something that appeals to consumers. In this study, the plant Terminalia bellirica was taken for study due to the mesmerizing medicinal properties of the plant. The antibacterial activities of acetone, ethyl acetate, benzene and methanol extracts of Terminalia bellirica stem bark were tested for four pathogenic bacterial strains by agar disc diffusion method. Among the various extract, acetone extracts showed good antibacterial activity and maximum zone of inhibition was obtained for Staphylococus aureus (zone size 8mm) followed by Pseudomonas aurogenosa (10mm). The results are given in Table-1. Methanol extract showed antibacterial activity against E. coli (zone size 8mm). On the other hand ethyl acetate and benzene extract was found to be totally unaffected against these bacterial strains.","PeriodicalId":432227,"journal":{"name":"Universities' Journal of Phytochemistry and Ayurvedic Heights","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130486463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cell based models for validation of safety of cosmetic products and ingredients 化妆品和成分安全性验证的细胞模型

Universities' Journal of Phytochemistry and Ayurvedic Heights Pub Date : 2023-06-24 DOI: 10.51129/ujpah-2022-34-1(2)

Nikhil Singh

引用次数: 0

Antimicrobial potentials of plant extracts against drug resistant bacteria 植物提取物对耐药细菌的抑菌活性研究

Universities' Journal of Phytochemistry and Ayurvedic Heights Pub Date : 2023-06-24 DOI: 10.51129/ujpah-2022-34-1(6)

S. Farooq, Z. Mehmood, A. K. Dixit

{"title":"Antimicrobial potentials of plant extracts against drug resistant bacteria","authors":"S. Farooq, Z. Mehmood, A. K. Dixit","doi":"10.51129/ujpah-2022-34-1(6)","DOIUrl":"https://doi.org/10.51129/ujpah-2022-34-1(6)","url":null,"abstract":"Antimicrobial resistance (AMR) is a serious and growing threat to human health. The development of new antibiotics is limited and slow. The tradition of synergy in herbal medicine is being used as a source of research ideas. The in vitro findings were that most of the research reported synergy both within plants and between plants and antibiotics. Whole plant extracts and combinations of compounds were shown to be more effective antimicrobials than isolated constituents. New sources of antimicrobial drugs need to be identified and improved strategy should be developed to combat multidrug resistance problem in pathogenic bacteria. Plant extract and phytochemicals demonstrating antimicrobial action needs to be exploited for their synergistic action between extracts and with antibiotics to exploit it in modern phytomedicine and combinational therapy. In the present study alcoholic extracts of medicinal plants were screened for their antimicrobial efficacy against drug resistant bacteria. The extracts of Hemidesmus indicus,and Carum copticum, showed promising action against one or more drug resistant bacteria with MIC ranged from 0.53 mg/ml to 7.80 mg/ml which has indicated their potential to be exploited in antimicrobial therapy and combination drug therapy after careful evaluation in vivo model.","PeriodicalId":432227,"journal":{"name":"Universities' Journal of Phytochemistry and Ayurvedic Heights","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127325964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective role of Withania somnifera root extract on lipid peroxidation of Erythrocytes 苦参根提取物对红细胞脂质过氧化的保护作用

Universities' Journal of Phytochemistry and Ayurvedic Heights Pub Date : 2022-12-24 DOI: 10.51129/ujpah-2022-33-2(1)

M. A. Abu Zaid, M. Chauhan, Swarndeep Chauhan

{"title":"Protective role of Withania somnifera root extract on lipid peroxidation of Erythrocytes","authors":"M. A. Abu Zaid, M. Chauhan, Swarndeep Chauhan","doi":"10.51129/ujpah-2022-33-2(1)","DOIUrl":"https://doi.org/10.51129/ujpah-2022-33-2(1)","url":null,"abstract":"Withania Somnifera (Ashwagandha) is an important medicinal plant that has been used in Ayurvedic and indigenous medicine. It is also known as Indian ginseng. It exerts antioxidant, anti-inflammatory and immune modulatory activities. In the present study, we studied the free radical scavenging activity of Withania Somnifera root extract. The radical scavenging effect of the extract was studied by its effect on hydroxy radicals generated by Fe-ascorbate-H2O2 system. Our results showed that Withania Somnifera root extract (1-10,000 µg/ ml) resulted in a significant dose dependent increase in percent inhibition of hydroxylation. Further, we studied the in vitro effect of Withania Somnifera root extract on Lipid peroxidation in terms of MDA level of human erythrocytes. Our results showed a significant dose dependent decrease in lipid peroxidation at a concentration of (1-1000 µg/ ml) as evident by decrease in level of MDA. Maximum effect was observed at 100-1000 µg/ ml. Withania Somnifera root extract thus can act as a potential antioxidant containing compound and protects erythrocytes from oxidative damage by either directly scavenging the free radical, sparing it or activating other enzymatic processes. At higher concentration (10,000 µg/ ml), Withania Somnifera extract increased the oxidative stress as evident from erythrocyte MDA level which became significantly more than the maximum effect shown at 1000 µg/ ml of extract.","PeriodicalId":432227,"journal":{"name":"Universities' Journal of Phytochemistry and Ayurvedic Heights","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124209740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inhibitory activity of organic solvent extracts of Murraya koenigii on Staphylococcus aureus 金银花有机溶剂提取物对金黄色葡萄球菌的抑制活性研究

Universities' Journal of Phytochemistry and Ayurvedic Heights Pub Date : 2022-12-24 DOI: 10.51129/ujpah-2022-33-2(11)

Sonakshi Chandra

{"title":"Inhibitory activity of organic solvent extracts of Murraya koenigii on Staphylococcus aureus","authors":"Sonakshi Chandra","doi":"10.51129/ujpah-2022-33-2(11)","DOIUrl":"https://doi.org/10.51129/ujpah-2022-33-2(11)","url":null,"abstract":"Staphylococcus aureus is one of the most in famous and widespread bacterial pathogen. This pathogen can cause a wide variety of diseases, ranging from moderately severe skin infections to fatal pneumonia and sepsis. Treatment of Staph. aureus infections is complicated due to antibiotic resistance. There has been ongoing and increasing interest in the extraordinarily high number of toxins and other virulence determinants that Staph. aureus produces and how they impact disease. In the past few decades, a more dangerous form of Staph.aureus has emerged. This form is known as Methicillin-Resistant Staph.aureus and usually referred to by the acronym MRSA. Keeping in view of the problem of Antimicrobial Resistance(AMR).This study was designed to explore antibacterial activity of a common kitchen herb Murraya koengii against pathogenic gram positive Staphylococcus aureus.Four different plant extracts were prepared using solvents- Methanol, Hexane, Aqueous and Ethanol+Aqueous (1:1) and tested against Staphylococcus aureus by using Kirby bauer Disc diffusion method. Methicillin antibiotic disc was used as the positive control.","PeriodicalId":432227,"journal":{"name":"Universities' Journal of Phytochemistry and Ayurvedic Heights","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124434488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0