Cyperus scariosus rhizome essential oil - physio-chemical characteristics and anxiolytic potential

Abstract

Essential oils are important plant products that often have a complicated composition made up of the volatile plant components. Numerous biological actions are reportedly connected to essential oils, and a new class of aromaceuticals is being developed. The market for essential oils has increased since they are used to cure these types of ailments as a result of the emergence of various mental issues due to changing living standards, such as depression, anxiety, sleeplessness, and stress. Studies on animal models have shown that the mode of action of essential oils, which cause physiological changes in the brain, involves a number of neurotransmitter systems. Despite mounting proof that essential oils have quantifiable effects on animal behavior. Therefore the current study is proposed to investigate the physical and chemical characteristics of the essential oil obtained from the rhizome of Cyperus scariosus and assess its anxiolytic effects on the central nervous system in rodent models. Hydro distillation was used to extract the essential oil from the rhizomes of the plant. Total yield, physical properties like viscosity, specific gravity, refractive index, acidity, saponification, iodine no, etc were examined .Further to determine its impact on the central nervous system in a rodent model studies were performed at a dose level of 250 mg/kg body weight and compared to the benchmark medication caffeine @100 mg/kg body weight. The essential oil has a sustainably stimulating impact on the central nervous system in a proportion of 88% compared to caffeine's 68%, according to CNS locomotors count and physicochemical features that were in good accordance with literature value.