Precision and Future Medicine最新文献

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Survival rate and death risk for associated pulmonary arterial hypertension: A retrospective population-based study 伴发肺动脉高压的存活率和死亡风险:基于人群的回顾性研究
IF 0.5
Precision and Future Medicine Pub Date : 2024-03-31 DOI: 10.23838/pfm.2023.00142
Sujin Kim, Shin Yi Jang, Soo Yeon Lee, S. Seo, S. Yi, C. Lee, Eun Jeong Cho, Kyeongsug Kim
{"title":"Survival rate and death risk for associated pulmonary arterial hypertension: A retrospective population-based study","authors":"Sujin Kim, Shin Yi Jang, Soo Yeon Lee, S. Seo, S. Yi, C. Lee, Eun Jeong Cho, Kyeongsug Kim","doi":"10.23838/pfm.2023.00142","DOIUrl":"https://doi.org/10.23838/pfm.2023.00142","url":null,"abstract":"Purpose: This study aimed to assess the survival rate (SR) and death risk for associated pulmonary arterial hypertension (aPAH; 10th revision of the International Statistical Classification of Diseases [ICD-10], I27.2) in Koreans.Methods: The data were collected from the Korean National Health Insurance Service from 2006 through 2017 (n= 15,448). We analyzed the SR using the Kaplan-Meier method and carried out Cox proportional hazards analyses.Results: Patients’ mean age upon aPAH diagnosis was 60.1±24.0 years, and 60.7% of the patients were female. The 10-year SR of aPAH was 46.3% (95% confidence interval, 45.0 to 47.6). The factors associated with an increase in the adjusted death risk included age of 0 to 9 years, advancing age, male sex, lower income level, and comorbidities including diabetes mellitus, myocardial infarction, heart failure, hemorrhagic stroke, chronic kidney disease, malignant neoplasm, hereditary hemorrhagic telangiectasia, and systemic lupus erythematosus.Conclusion: The 10-year SR of aPAH was over 46%. The risk of death from aPAH was significantly higher with advancing age, sex, lower income level, and comorbidities.","PeriodicalId":42462,"journal":{"name":"Precision and Future Medicine","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140358159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding hikikomori syndrome in clinical settings: a case series 在临床环境中了解蛰居综合征:病例系列
IF 0.5
Precision and Future Medicine Pub Date : 2024-03-31 DOI: 10.23838/pfm.2024.00009
Ji Hyun An, Sohee Park, J. Jung, Jin Pyo Hong
{"title":"Understanding hikikomori syndrome in clinical settings: a case series","authors":"Ji Hyun An, Sohee Park, J. Jung, Jin Pyo Hong","doi":"10.23838/pfm.2024.00009","DOIUrl":"https://doi.org/10.23838/pfm.2024.00009","url":null,"abstract":"Hikikomori syndrome (HS), a phenomenon characterized by social withdrawal and isolation, has attracted significant attention in both academic and clinical settings. However, understanding the diverse nature of HS remains a challenge due to its multifaceted etiology and presentation. This paper aims to shed light on this phenomenon by examining three representative typologies of HS in clinical settings. Through detailed case analyses, we categorize HS into three main types: HS associated with neurodevelopmental disorders; HS triggered by the onset of mental illness; and HS emerging gradually with age-related challenges. By elucidating these typologies, we provide insights into the complex interplay of psychological, social, and developmental factors contributing to HS, thereby facilitating more tailored approaches for the evaluation of and intervention into this syndrome in clinical practice.","PeriodicalId":42462,"journal":{"name":"Precision and Future Medicine","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140359561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of colistin resistance via heteroresistance modeling in Klebsiella pneumoniae: A diagnostic study 肺炎克雷伯氏菌通过异抗性模型产生对可乐定的耐药性:诊断研究
IF 0.5
Precision and Future Medicine Pub Date : 2024-02-14 DOI: 10.23838/pfm.2023.00184
Jungyu Seo, K. Ko
{"title":"Development of colistin resistance via heteroresistance modeling in Klebsiella pneumoniae: A diagnostic study","authors":"Jungyu Seo, K. Ko","doi":"10.23838/pfm.2023.00184","DOIUrl":"https://doi.org/10.23838/pfm.2023.00184","url":null,"abstract":"","PeriodicalId":42462,"journal":{"name":"Precision and Future Medicine","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139777662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Durable response to first-line treatment with AZD3759 (zorifertinib) in a patient with epithelial growth factor receptor mutated non-small cell lung cancer and untreated multiple brain metastasis 一名上皮生长因子受体突变的非小细胞肺癌患者接受AZD3759(佐非替尼)一线治疗后出现持久反应,且多处脑转移瘤未经治疗
IF 0.5
Precision and Future Medicine Pub Date : 2024-02-14 DOI: 10.23838/pfm.2023.00170
Junho Lee, Myung-Ju Ahn, Sehhoon Park
{"title":"Durable response to first-line treatment with AZD3759 (zorifertinib) in a patient with epithelial growth factor receptor mutated non-small cell lung cancer and untreated multiple brain metastasis","authors":"Junho Lee, Myung-Ju Ahn, Sehhoon Park","doi":"10.23838/pfm.2023.00170","DOIUrl":"https://doi.org/10.23838/pfm.2023.00170","url":null,"abstract":"","PeriodicalId":42462,"journal":{"name":"Precision and Future Medicine","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139779285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paraneoplastic neurological syndrome associated with onconeural autoantibodies: report of two cases 与肿瘤自身抗体相关的副肿瘤性神经综合征:两个病例的报告
IF 0.5
Precision and Future Medicine Pub Date : 2024-02-14 DOI: 10.23838/pfm.2023.00149
Panagiotis Kalmoukos, Christina Kouparani, Nikoletta Moscha, Dimitrios Kouroupis, Evangelia Giza, Georgios Sapouridis, Elisavet Simoulidou, A. Varouktsi, S. Chatzimichailidou, Konstantinos Petidis, A. Pyrpasopoulou
{"title":"Paraneoplastic neurological syndrome associated with onconeural autoantibodies: report of two cases","authors":"Panagiotis Kalmoukos, Christina Kouparani, Nikoletta Moscha, Dimitrios Kouroupis, Evangelia Giza, Georgios Sapouridis, Elisavet Simoulidou, A. Varouktsi, S. Chatzimichailidou, Konstantinos Petidis, A. Pyrpasopoulou","doi":"10.23838/pfm.2023.00149","DOIUrl":"https://doi.org/10.23838/pfm.2023.00149","url":null,"abstract":"","PeriodicalId":42462,"journal":{"name":"Precision and Future Medicine","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139779256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of colistin resistance via heteroresistance modeling in Klebsiella pneumoniae: A diagnostic study 肺炎克雷伯氏菌通过异抗性模型产生对可乐定的耐药性:诊断研究
IF 0.5
Precision and Future Medicine Pub Date : 2024-02-14 DOI: 10.23838/pfm.2023.00184
Jungyu Seo, K. Ko
{"title":"Development of colistin resistance via heteroresistance modeling in Klebsiella pneumoniae: A diagnostic study","authors":"Jungyu Seo, K. Ko","doi":"10.23838/pfm.2023.00184","DOIUrl":"https://doi.org/10.23838/pfm.2023.00184","url":null,"abstract":"","PeriodicalId":42462,"journal":{"name":"Precision and Future Medicine","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139837261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Durable response to first-line treatment with AZD3759 (zorifertinib) in a patient with epithelial growth factor receptor mutated non-small cell lung cancer and untreated multiple brain metastasis 一名上皮生长因子受体突变的非小细胞肺癌患者接受AZD3759(佐非替尼)一线治疗后出现持久反应,且多处脑转移瘤未经治疗
IF 0.5
Precision and Future Medicine Pub Date : 2024-02-14 DOI: 10.23838/pfm.2023.00170
Junho Lee, Myung-Ju Ahn, Sehhoon Park
{"title":"Durable response to first-line treatment with AZD3759 (zorifertinib) in a patient with epithelial growth factor receptor mutated non-small cell lung cancer and untreated multiple brain metastasis","authors":"Junho Lee, Myung-Ju Ahn, Sehhoon Park","doi":"10.23838/pfm.2023.00170","DOIUrl":"https://doi.org/10.23838/pfm.2023.00170","url":null,"abstract":"","PeriodicalId":42462,"journal":{"name":"Precision and Future Medicine","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139838970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paraneoplastic neurological syndrome associated with onconeural autoantibodies: report of two cases 与肿瘤自身抗体相关的副肿瘤性神经综合征:两个病例的报告
IF 0.5
Precision and Future Medicine Pub Date : 2024-02-14 DOI: 10.23838/pfm.2023.00149
Panagiotis Kalmoukos, Christina Kouparani, Nikoletta Moscha, Dimitrios Kouroupis, Evangelia Giza, Georgios Sapouridis, Elisavet Simoulidou, A. Varouktsi, S. Chatzimichailidou, Konstantinos Petidis, A. Pyrpasopoulou
{"title":"Paraneoplastic neurological syndrome associated with onconeural autoantibodies: report of two cases","authors":"Panagiotis Kalmoukos, Christina Kouparani, Nikoletta Moscha, Dimitrios Kouroupis, Evangelia Giza, Georgios Sapouridis, Elisavet Simoulidou, A. Varouktsi, S. Chatzimichailidou, Konstantinos Petidis, A. Pyrpasopoulou","doi":"10.23838/pfm.2023.00149","DOIUrl":"https://doi.org/10.23838/pfm.2023.00149","url":null,"abstract":"","PeriodicalId":42462,"journal":{"name":"Precision and Future Medicine","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139839010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of acute invasive fungal sinusitis in an immunocompetent patient on glatiramer acetate therapy 一名接受醋酸格拉替雷治疗的免疫功能正常患者的急性侵袭性真菌性鼻窦炎病例
IF 0.5
Precision and Future Medicine Pub Date : 2023-12-31 DOI: 10.23838/pfm.2023.00114
Melanie Hicks, J. Bishop, Brenton T. Bicknell, J. Grayson, B. Woodworth, D. Cho
{"title":"A case of acute invasive fungal sinusitis in an immunocompetent patient on glatiramer acetate therapy","authors":"Melanie Hicks, J. Bishop, Brenton T. Bicknell, J. Grayson, B. Woodworth, D. Cho","doi":"10.23838/pfm.2023.00114","DOIUrl":"https://doi.org/10.23838/pfm.2023.00114","url":null,"abstract":"Acute invasive fungal sinusitis (AIFS) is a rapidly progressing, life-threatening infection. The advent of immunomodulatory therapies has expanded the population susceptible to AIFS. In this case report, we describe a patient who defies the conventional profile of AIFS. This 70-year-old woman is immunocompetent and non-diabetic, with a history of multiple sclerosis (MS) and ongoing treatment with glatiramer acetate (GA), immunomodulator. She came to the emergency room due to acute vision changes, and images revealed an enhancing mass in the left pterygopalatine fossa. The diagnosis of AIFS was confirmed by biopsy in the operating room. Subsequently, anti-fungal therapies were initiated with a follow-up operative debridement. Follow-up magnetic resonance imaging (10 months since treatment) showed no progression of AIFS. GA was discontinued since the diagnosis, and MS has remained stable. Recognizing this unique group of atrisk patients is crucial, as early detection and treatment play a pivotal role in preventing significant morbidity and mortality.","PeriodicalId":42462,"journal":{"name":"Precision and Future Medicine","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139132311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Central positional nystagmus due to acute medial medullary infarction 急性内髓梗死引起的中枢性位置性眼球震颤
Precision and Future Medicine Pub Date : 2023-11-13 DOI: 10.23838/pfm.2023.00093
Seong-Joon Lee, Yoon Seob Kim, Jin Soo Lee, Ji Man Hong
{"title":"Central positional nystagmus due to acute medial medullary infarction","authors":"Seong-Joon Lee, Yoon Seob Kim, Jin Soo Lee, Ji Man Hong","doi":"10.23838/pfm.2023.00093","DOIUrl":"https://doi.org/10.23838/pfm.2023.00093","url":null,"abstract":"A 70-year-old male with risk factors for vascular disease presented with dizziness and instability. The patient showed horizontal geotropic nystagmus when turning his head while lying down, with larger slow phase velocity observed when turning to the left. There were no other neurological deficits. Video head impulse tests and vestibular evoked myogenic potentials were normal. The initial magnetic resonance imaging (MRI) findings were negative; however, the patient experienced subsequent right-side weakness, right tilting, and recurrent episodes of vertigo. A follow-up MRI revealed an acute left medial medullary infarction, which seems to have caused the paroxysmal geotropic central positional nystagmus in this patient.","PeriodicalId":42462,"journal":{"name":"Precision and Future Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136281460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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