International Journal of Medical Laboratory Research最新文献

{"title":"A RARE CASE OF SMALL BOWEL PNEUMATOSIS INTESTINALIS","authors":"N. Ganesan, S. Vidhyalakshmi, R. Kartikayan, M. Muruganand","doi":"10.35503/ijmlr.2020.5105","DOIUrl":"https://doi.org/10.35503/ijmlr.2020.5105","url":null,"abstract":": Pneumatosisintestinalis (PI) also called as pneumatosiscystoidesintestinalis) is the presence of multiple gas/ air filled cysts in the bowel wall. The pathogenesis is poorly understood and is probably multifactorial. The presentation may be either an incidental diagnosis or may be associated with various gastrointestinal diseases. We report a case of 76- year- old male presented with intestinal obstruction symptoms, diagnosed to be small bowel PI associated with lymphangiectasia. In this report we emphasize the pathogenesis of PI due to lymphatic disruption.","PeriodicalId":420042,"journal":{"name":"International Journal of Medical Laboratory Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123772496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IMPACT OF ROAD TRAFFIC INJURY ON JOB LOSS AND FINANCIAL COSTS: A PILOT STUDY FROM A TERTIARY CARE CENTRE","authors":"Simon P, Geevarughese NM, Bhat K, George T, Colin Md, D’souza S, Varghese Nk, Chacko J, Baliga MS","doi":"10.35503/ijmlr.2022.7302","DOIUrl":"https://doi.org/10.35503/ijmlr.2022.7302","url":null,"abstract":"Introduction: Global studies have shown that majority of those affected in road traffic accidents (RTA) are young and bread winners of their families. Depending on the part afflicted, most non-fatal injuries have either temporary disability or life-long sequels, which require job modification, rehabilitation and integration back into work and society. However, despite recovery the traumatic experience and disability impact the affected individual and their family. Through this pilot study, an attempt was made to understand the impact of RTA on an individual’s financial status, cost cutting behaviour and sleep affection. Methods: Data was collected during follow-up of patients who were treated for traumatic injuries. Patients were assessed by a selfdesigned questionnaire regarding their financial burdens arising out of injury and treatment, sacrifices in regular life, return to work and losses incurred due to the trauma. Results: A total of 162 patients volunteered to be a part of the study and 76.5% earned below ₹25,000 per month. Data indicated 25% had to pledge their valuables to pay for hospital charges, 79% cut costs on luxury goods and 75% cut on non-essential and recreational activities. At the end of one-month post-accident, more than 43% of participants needed to spend more than thirty minutes to fall asleep and 21% had disturbed sleep. Conclusion: Lower economic status, rural place of residence, lack of insurance and treatment at private health facilities are the key drivers for increased risk of high healthcare expenditure on road traffic injuries. On an individual basis, these cause costly rehabilitation, difficult work atmosphere, sacrifices in personal life and delayed comeback to societal living.","PeriodicalId":420042,"journal":{"name":"International Journal of Medical Laboratory Research","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133133885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CLINICO-LABORATORY PROFILE OF PATIENTS AFFECTED WITH PULMONARY TUBERCULOSIS: RETROSPECTIVE OBSERVATIONS FROM A TERTIARY CARE HOSPITAL","authors":"A. Challapalli, F. Fazal, M. Pais, M. Adnan, RP Jakribettu, R. Boloor, Mohan R Baliga","doi":"10.35503/ijmlr.2020.5203","DOIUrl":"https://doi.org/10.35503/ijmlr.2020.5203","url":null,"abstract":"Background: Globally, tuberculosis (TB) is one of the top 10 causes of death and India, is one among the leading contributors. This study was undertaken to assess the clinic-laboratory profile of the patients diagnosed with Pulmonary TB (PTB) and evaluate differences between dead and alive PTB patients. Material and methods: : This is a retrospective study, conducted in the patients diagnosed with PTB from January 2016 to December 2018. The clinical, hematological and biochemical parameters of the patients diagnosed with Pulmonary TB at the time of presentation to the tertiary care hospital was noted and compared among the age matched healthy individuals. We further looked for prognostic factors among the tuberculosis patients who died and survived. Results: A total of 209 patients were diagnosed with PTB during the study period. The prevalence of TB was higher in males. Most of the TB patients belonged to the age group 31-60 years. Among the PTB patients, cough with expectoration was the most common symptoms followed by fever and breathlessness. Nearly 50% patients had symptoms for less than 2 weeks. The right upper zone was the most common zone involved radiologically. When compared to healthy individuals, TB patients had significantly low haemoglobin, while there was raise in total leukocyte count, platelet count ESR, Blood urea, and LFT. The mortality in TB patients was associated with low haemoglobin, lower differential macrophage count and lower globulin. Conclusion: In our study population, PTB was common in males, and in age group of 31-60 years. Patients with Cough with expectoration with 2 weeks duration, anaemic, leucocytosis and raised ESR must be investigated extensively for Pulmonary TB. Patients (PTB) with were severe anaemia and lower differential macrophage count had higher mortality rate.","PeriodicalId":420042,"journal":{"name":"International Journal of Medical Laboratory Research","volume":"120 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134263491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPARISON OF ANTIBIOTIC SUSCEPTIBILITIES OF CARBAPENEM RESISTANT AND CARBAPENEMSUSCEPTIBLE PSEUDOMONAS AERUGINOSA STRAINS AND INVESTIGATING SOME CARBAPENEMASE GENES IN CARBAPENEM RESISTANT STRAINS","authors":"Vecihe Azizoğlu, B. Ozer, A. Gundoğdu","doi":"10.35503/ijmlr.2021.6303","DOIUrl":"https://doi.org/10.35503/ijmlr.2021.6303","url":null,"abstract":"Aim: It was aimed to compare the antimicrobial susceptibility of carbapenem resistant (CRPA) andsusceptible P. aeruginosa (CSPA) strains and to determine the presence of carbapenemasegenes in CRPA strains. Methods: Fifty CRPA and 251 CSPA were included into the study. Antibiotic susceptibilities were determined using the automated system. The presence of carbapenemasegenes (blaIMP, blaSPM, blaAIM, blaNDM, blaOXA-48, blaKPC) in CRPA strains were investigated by multiplex polymerase chain reaction method. Results: CRPA isolates were found to be more resistant to amikacin, aztreonam, gentamicin, netilmicin, tobramycin, ciprofloxacin, levofloxacin, cefepime, ceftazidime, piperacillin, piperacillin / tazobactamthan CSPA. Amikacin, aztreonam, ceftazidime, ciprofloxacin, colistin, cefepime, gentamicin, levofloxacin, netilmycin, piperacillin, tobramycin, piperacillin/tazobactam MIC values of CRPA strains were found to be higher than MIC values of CSPA strains. The multidrug resistance (MDR) rate was 14,6% and higher in the CRPA group. Inthe CRPA strains, among blaIMP, blaVIM, blaSPM, blaNDM, blaKPC, blaAIM and blaOXAgenes, blaIMP was found in one strain and blaVIM gene in three strains. Conclusions: The carbapenem resistance and MDR rate in ours tudy, were found to be lesser than the rates in our country. It was found that CRPA were also more resistant to other antibiotics than CSPA. IMP and VIM type enzymes were found in our study. Together with other studies conducted in our hospital, this study showed that carbapenemases were not common in P. Aeruginosa strains isolated in our hospital. Identifying these enzymes epidemiologically is important in preventing the spread of resistance. KEYWORD: P. aeruginosa, antibiotic, resistance, carbapenem, carbapenemase RESEARCH ARTICLE Corresponding Author: Prof. Burcin Ozer, MD, PhD HatayMustafa Kemal University, School of Medicine, Department of Medical Microbiology, TayfurSokmen Campus, 31060, Alahan/HATAY/TURKEY ISSN No. 2456-4400 Int J Med Lab Res 2021, 6(3):16-26 International Journal of Medical Laboratory Research (Vol. 6 Issue 3, December 2021) www.ijmlr.com/IJMLR© All rights are reserved","PeriodicalId":420042,"journal":{"name":"International Journal of Medical Laboratory Research","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130033412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COLLISION TUMOR OF OVARY: SEROUS ADENOCARCINOMA AND MATURE CYSTIC TERATOMA","authors":"S. Rahar, S. Khetarpal","doi":"10.35503/ijmlr.2019.4207","DOIUrl":"https://doi.org/10.35503/ijmlr.2019.4207","url":null,"abstract":"Collision tumor is tumors which are composed of two histologically distinct tumors in the same organ without any intermixing of two components. Simultaneous coexistence of high grade serous adenocarcinoma with mature cystic teratoma is quite rare with only five cases reported till date. In this case report, we present an ovarian collision tumor in a 60 year old female.","PeriodicalId":420042,"journal":{"name":"International Journal of Medical Laboratory Research","volume":"284 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132871242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TWENTY-YEAR TRENDS IN ANTIMICROBIAL RESISTANCES AMONG PSEUDOMONAS AERUGINOSA CLINICAL ISOLATES","authors":"J. Intra, Claudia Siracusa, M. R. Sala, V. Leoni, P. Brambilla, D. Carcione","doi":"10.35503/ijmlr.2021.6304","DOIUrl":"https://doi.org/10.35503/ijmlr.2021.6304","url":null,"abstract":"We retrospectively analyzed the antimicrobial data of P. aeruginosa strains isolated from hospitalized subjects and outpatients over a 20-year period (2000-2019). A total of 2,588 unique P. aeruginosa strains, 588 from outpatients (23 %) and 2,000 from hospitalized subjects (77 %), were retrieved. Except gentamicin and ciprofloxacin, which showed significant antibiotic decreasing trends, all the antimicrobial agents tested did not show significantly changes in both groups (p < 0.01). There were significant increasing resistance trends for all antibiotics, except gentamicin and ciprofloxacin in P. aeruginosa strains isolated from respiratory tract samples (p < 0.05), and for meropenem and piperacillin-tazobactam in urine samples from subjects with and without urinary catheter (p < 0.05). Moreover, there was a significant increase in multidrug resistant isolates (p < 0.05). Monitoring antibiotic resistances at local and regional levels are required in order to reduce inappropriate antimicrobial consumption, to increase the focus on antimicrobial stewardship. KEYWORD: Antibiotic resistance, Pseudomonas aeruginosa, Epidemiology, Carbapenem resistance, Surveillance","PeriodicalId":420042,"journal":{"name":"International Journal of Medical Laboratory Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114430376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TEETH AS A SOURCE OF DNA FOR FORENSIC INVESTIGATION - A REVIEW","authors":"Saisha Nayyer, A. Jaiswal","doi":"10.35503/ijmlr.2022.7205","DOIUrl":"https://doi.org/10.35503/ijmlr.2022.7205","url":null,"abstract":"Teeth are one of the most resilient structures in the human body, with respect to incineration, immersion, trauma, mutilation, and decomposition, and thus, are used in forensic investigations. Hard tissues like Teeth apart from bones are rich sources of DNA. The calcified nature of bones and teeth helps to keep them preserved when other parts of the body are destroyed or degraded in mass disasters. Teeth are frequently chosen sources of DNA because of their special makeup and location within the jawbone, which offers more protection to DNA than bones. Teeth with larger pulp and multi-root contain many pulp cells and have more tooth cementum, compared to single-root teeth. Regardless of the sort of laboratory process adopted or the time since death, studies have shown that molars and premolars are suitable candidates for obtaining DNA profiles. The aim of this article is to collate all information regarding tools and methodologies pertaining to isolating DNA from tooth samples and highlighting its importance in forensic science. This article puts forth a literature review referring to the main studies on DNA from the tooth that involve the utilization of teeth for purposes like human identification, all the while making an overview of the evolution of this technology in the last years, highlighting the importance of techniques used to isolate and analyse DNA from teeth in forensic sciences.","PeriodicalId":420042,"journal":{"name":"International Journal of Medical Laboratory Research","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115927535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“A ROBUST METHOD FOR REDUCING SAMPLE RETRIEVAL TAT IN CLINICAL LABORATORY SETUP AT ZERO ADDED INVESTMENT.”","authors":"Anurag Yadav, Ramlingareddy, Avinash Ss, M. M.","doi":"10.35503/ijmlr.2022.7203","DOIUrl":"https://doi.org/10.35503/ijmlr.2022.7203","url":null,"abstract":"Background: The concept of Total Laboratory Automation (TLA) is shifting towards the automation in individual process i.e., Task Targeted automation (TTA). Sample storage is one of the key areas in the Total Testing Process (TTP), hence we developed a robust method to reduce the TAT for blood sample retrieval in clinical biochemistry laboratory with zero added investment. We compared the sample retrieval time (TAT) improvement in sample retrieval with the old conventional and the new method of sample storage. Material and method: study was conducted at a medium-large scale lab with average sample of 1000-1200 per day. The blood sample vacutainers are stored in the refrigerator at controlled temperature for the duration of 48hrs as the lab policy. We requested the technicians to retrieve 10 patient samples from the storage for the duration of 5 days, with different person allotted each day. The samples for day were stored and retrieved the requested sample by conventional & new method. Result: our new method has shown a good improvement in the TAT for the retrieval of the stored blood sample for the retesting or the added parameter for testing on request. The conventional method had an average time to identify and retrieve sample was 9.2mins, which was significantly decreased to 1.4mins with the new method of sample storage and retrieval system. Conclusion: Study emphasis this procedure / process will help the small and medium scale laboratories in having a robust method of sample storage and retrieval at a very short TAT with a minimal or no extra investment.","PeriodicalId":420042,"journal":{"name":"International Journal of Medical Laboratory Research","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123319772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}